Piascladin 300

Piascladin 300 is a phytopreparation regulating metabolic processes in the cartilaginous tissue. Has a symptomatic analgesic and anti-inflammatory effect on the joints.

It helps to slow down the degenerative process in the cartilaginous tissue of joints, reduces joint pain associated with this process, restores motor function.

In the experimental studies it was proved that the drug has a regenerating effect on the cartilage, stimulating the synthesis of collagen in articular chondrocytes. The effect of unsaponifiable soybean oil and avocado oil compounds increases the production of collagen and inhibits the stimulating effect of interleukin-1 (IL-1) on the synthesis of collagenase.

Clinical and pharmacological group

A drug that regulates metabolism in cartilage tissue.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Piascladin 300 cost in pharmacies? The average price in 2018 is at the level of1 400 rubles.


Form of issue and composition

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Piascladin 300 is available in the form of capsules (type I) with an opaque white casing and a white cap that has the marking "Р 300 the contents - brown paste (15 pieces in blisters, in a cardboard bundle 1 or 2 blister).

Active ingredients (in 1 capsule):

  • Unsaponifiable compounds of soybean oil - 200 mg;
  • Unsaponifiable compounds of avocado oil - 100 mg.

Auxiliary components: silicon colloidal dioxide, butylhydroxytoluene.

Composition of capsule body and capsule: up to 100% gelatin and 2% titanium dioxide.

Composition of the capsule sealing solution: gelatin and polysorbate 80.

The composition of ink for the labeling of the capsule: isopropanol, propylene glycol, potassium hydroxide, shellac, butanol, ethanol, concentrated ammonia solution, iron oxide black.

Pharmacological effect

The action of Piascladin 300 includes the correction of the metabolism of the cartilaginous tissue.

This drug has anti-inflammatory and analgesic effects on the joints. Piascladin 300 slows down degenerative processes in the cartilaginous tissue of the joints, reduces pain and restores motor function. Application of the drug has a regenerating effect on cartilage, and also stimulates the synthesis of collagen in articular chondrocytes.

Piascladin 300 due to the soya bean and avocado oil contained in it, stimulates the effect of IL-1 on the synthesis of collagenase, increases the production of collagen; activating the degradation of proteoglycans, prevents the destruction of cartilage; stimulates the synthesis of hyaline cartilage and macromolecules of periodontal tissue, which significantly reduces loss of teeth.

Indications for use

Piascladin is widely used in rheumatology and dentistry. Its use is shown in therapy:

  1. Osteochondrosis of the spine.
  2. Periodontitis.
  3. All kinds of osteoarthritis (periarthritis, arthrosis of various joints like coxarthrosis, gonarthrosis, tenosynovitis, etc.).


The manufacturer in the instructions to the drug indicates a number of contraindications:

  1. Lactation and pregnancy;
  2. Age to 18;
  3. Individual intolerance to the drug or its individual components.

Use in pregnancy and lactation

Since the safety of the effect of the drug on intrauterine development of the fetus is not established, and experience the use of this drug among future mothers is not available, the capsules are not prescribed for treatment pregnant women.

It is not known whether the components of the drug are excreted in breast milk and how this can affect the baby, so Piaskledin capsules are not prescribed for the treatment of nursing mothers. If therapy is necessary, the question of completing breastfeeding should be addressed.

Dosage and route of administration

In the instructions for use, it is indicated that Piascladin 300 is ingested 1 capsule per day, preferably in the morning while eating, with 250 ml of water. The course of treatment is 6 months.

An increase in the duration and holding of repeated courses of treatment is possible after consultation with the doctor.


Side effects

Like any other drug, Piascladin 300 has several possible side effects. The most common of these is allergies.

In addition, there may be changes in liver transaminase activity, alkaline phosphatase, γ-glutamyltransferase, and bilirubin.


Currently, cases of overdose with Piascladin 300 are not described, however, in order to avoid negative reactions it is not recommended to exceed the dose specified in the instructions. When accidentally ingesting a large number of capsules, you should induce vomiting, rinse the stomach to the patient and give take enterosorbents.

special instructions

At the initial stage of treatment, the use of Piascladin 300 can be combined with the intake of NSAIDs and / or analgesics.

Does not affect the activity requiring increased concentration of attention and speed of psychomotor reactions.

Drug Interactions

Information on the drug interaction of Piascladin 300 with other drugs / substances is absent.


We picked up some reviews of people who used the drug Piascladin 300:

  1. Oksana. I took NSAID for several years, because the osteochondrosis of the spine brought me almost to disability. From the pains she did not know where to put herself. Neither to bend - nor to straighten up at times could not. The treatment with Piascladin 300 and Don powder helped. I took these funds once a day. This treatment was given to me by a district rheumatologist. It was necessary to drink drugs for 3 months, but only after the end of the 2 month intake Piaskladin for some reason disappeared from pharmacies. It's a pity. I really liked his action. I believe that the integrated approach played an important role here. But my back began to hurt much less. As the drug will be on sale, I will immediately continue the course further.
  2. Natalia. For the first time with Piaskladin 300 met, when the doctor appointed me for osteochondrosis, then he only appeared. Then I almost crawled to the reception, my back ached so much. I'm allergic to most drugs, so I can not take them. After a week of taking these capsules, I already noticed a significant reduction in the pain syndrome, I was able to return to work. Now, every other year and a half I spend a preventive reception of this drug for 3 months. Osteochondrosis practically does not disturb.


Piascladin 300 is not unique in its kind, so there are many of its analogs.

Analogs of the agent for an effective substance:

  • Intralipid;
  • Nutriflex;
  • Lipofundin;
  • Oliklinomel;
  • Smokkabiven;
  • Smoklypide;

Similar to the therapeutic effect of drugs:

  • Alfolutop;
  • Glucosamine Sulphate 750;
  • Dimexide;
  • Diprospan;
  • Clynoril;
  • OrtoOsteo;
  • Chondramine;

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store at a temperature of 15-25 ° C in a place inaccessible to children and protected from light.

Shelf life - 3 years.

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