Universal assistance in the shortest time for a small price is acetylsalicylic acid.
It helps from a lot of ailments and pressing problems. In addition to the well-known useful properties, acetylsalicylic acid from headache is used by almost all people in a variety of situations.
On this page you will find all information about Acetylsalicylic acid: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Acetylsalicylic acid. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
NSAIDs. Has anti-inflammatory, analgesic and antipyretic effect, and also inhibits platelet aggregation.
Conditions of leave from pharmacies
Available without a prescription.
Price list
How much does Acetylsalicylic acid cost? The average price in pharmacies is at the level of15 rubles.
Form of issue and composition
Acetylsalicylic acid is available in tablets. The composition is represented by a different amount of active substance - 100, 250, 50 mg, supplemented with citric acid and potato starch.
Pharmacological effect
After taking acetylsalicylic acid in the body decreases hyperemia, decreases the permeability of capillaries at the site of inflammation - all this leads to a noticeable analgesic and anti-inflammatory effect. The drug quickly penetrates into all tissues and fluids, absorption occurs in the intestine and liver.
The action of acetylsalicylic acid:
- Reduces elevated body temperature, while not affecting normal performance;
- Eliminates pain of mild to moderate intensity;
- Acetylsalicylic acid dilutes blood, disrupts aggregation of platelets - reduces the load on the heart muscle, reduces the risk of heart attack;
- Provides a persistent anti-inflammatory effect 24-48 hours after the start of the drug.
The drug can be taken for the prevention of thrombosis, strokes, reducing the risk of circulatory disorders in the brain.
Indications for use
What helps these pills? Indications for Acetylsalicylic acid are:
- Feverish syndrome;
- Ischemic heart disease, thromboembolism, atrial fibrillation and myocardial infarction (as a prophylactic agent);
- Acute rheumatic fever, rheumatic chorea, Dressler's syndrome, rheumatoid arthritis;
- Diseases of the spine, which are accompanied by pain syndromes (lumbago, sciatica, osteochondrosis);
- Migraine, as well as head, joint, muscle, menstrual and dental pain, neuralgia, osteoarthritis;
- Acute thrombophlebitis, an infarct of the lung.
Contraindications
Tablets can not be taken in the following cases:
- "Aspirin triad";
- Hemophilia;
- Hypoprothrombinemia;
- Vitamin K deficiency;
- Renal and / or hepatic insufficiency;
- Deficiency of glucose-6-phosphate dehydrogenase;
- Children under 15;
- Reye's Syndrome;
- Portal hypertension;
- Hemorrhagic diathesis;
- The aortic dissecting aneurysm;
- I and III trimester of pregnancy, as well as lactation;
- Increased sensitivity to salicylates, incl. acetylsalicylic acid;
- Presence in the anamnesis of information about urticaria, rhinitis caused by taking this medication and / or other non-steroidal anti-inflammatory drugs;
- Exacerbations of erosive-ulcerative lesions of the gastrointestinal tract;
- Gastrointestinal bleeding;
With caution, under careful medical control use of medicines for liver and kidney problems, gastrointestinal problems in history, bronchial asthma, increased bleeding, decompensated chronic heart failure, in the second trimester of pregnancy and during anticoagulant therapy.
Application in pregnancy and lactation
Contraindicated in the I and III trimesters of pregnancy. In the second trimester of pregnancy, one-time administration is possible on strict indications.
Has a teratogenic effect: when applied in the first trimester leads to the development of cleavage of the upper palate, in the third trimester - causes inhibition of labor (inhibition synthesis of prostaglandins), premature closure of the arterial duct in the fetus, hyperplasia of the pulmonary vessels and hypertension in the small circulation.
Acetylsalicylic acid is excreted in breast milk, which increases the risk of bleeding in the child due to disturbance of function of thrombocytes, therefore, do not use acetylsalicylic acid in the mother during lactation.
Instructions for use
In the instructions for use, it is indicated that the acetylsalicylic acid tablets are intended for oral administration, preferably after eating, with milk, ordinary or alkaline mineral water.
- To apply to adults acetylsalicylic acid the instruction recommends 3-4 times a day for 1-2 tablets (500-1000 mg), with the maximum daily dose - 6 tablets (3 g). The maximum duration of the use of acetylsalicylic acid is 14 days.
- In order to improve the rheological properties of the blood, and also as an inhibitor of the adhesion of platelets, 1½ tablets of acetylsalicylic acid is prescribed per day for several months. With myocardial infarction and for the prevention of secondary myocardial infarction, the instruction for acetylsalicylic acid recommends taking 250 mg per day. Dynamic disorders of cerebral circulation and cerebral thromboembolism suggest taking ½ tablets of acetylsalicylic acid with a gradual dose of up to 2 tablets per day.
- Duration of treatment (without consulting a physician) should not exceed 7 days with an appointment as an analgesic and more than 3 days as an antipyretic.
Under the supervision of a doctoracetylsalicylic acid is prescribed to children in the following single doses: over 100 years, 100 mg for adults, 150 mg for the third year, 200 mg for 4 years, 250 mg for children over 5 years.
Side effects
Before starting the use of acetylsalicylic acid tablets, the patient should consult a doctor. If the dose is exceeded or uncontrolled and prolonged use of this drug, the following side effects may develop:
- Visual impairment;
- Bleeding - intestinal, nasal, gingival, gastric;
- Pain in the epigastric region, nausea, vomiting;
- Diarrhea;
- Dizziness and weakness;
- Loss of appetite;
- Development of acute renal failure;
- Bronchospasm, in severe cases development of angioedema and anaphylactic shock;
- Change in the clinical picture of blood - a decrease in the number of hemoglobin and platelets;
- Disorders in the work of the liver and kidney
Overdose
When using the drug in large quantities that do not meet the recommended dosage, negative body reactions are possible. Overdose leads to the appearance of the following problems:
- dehydration of the body;
- problems with hearing and vision;
- tremor;
- violation of acid-base balance and electrolyte;
- confusion of consciousness;
- nausea, accompanied by vomiting, the presence of pain in the abdomen;
- drowsy condition.
In rare cases, abuse of the drug leads to metabolic acidosis and coma.
special instructions
- Acetylsalicylic acid even in small doses reduces the excretion of uric acid from the body, which can cause an acute attack of gout in predisposed patients. When performing long-term therapy and / or using acetylsalicylic acid in high doses, it is necessary to observe the doctor and regularly check the level of hemoglobin.
- Before surgical intervention, to reduce bleeding during surgery and in the postoperative period, it is necessary to cancel the intake of salicylates for 5-7 days.
- The use of acetylsalicylic acid in pediatrics is contraindicated, since in the case of viral infection in children under the influence of acetylsalicylic acid, the risk of developing the Reye syndrome increases. Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, enlargement of the liver.
Compatibility with alcohol
Alcohol during ASA is contraindicated. This combination can cause gastric and intestinal bleeding, as well as severe hypersensitivity reactions.
Drug Interactions
With simultaneous use with acetylsalicylic acid:
- Antidiabetics - lowering blood sugar;
- Antatsida, containing magnesium and / or aluminum hydroxide, slow down and reduce the absorption of acetylsalicylic acid;
- Calcium channel blockers, drugs that limit the intake of calcium or increase the excretion of calcium from the body - increases the risk of bleeding;
- The effect of heparin and indirect anticoagulants, methotrexate, phenytoin, valproic acid increases;
- Acetylsalicylic acid can reduce plasma concentrations of indomethacin, Iroxicam;
- The effectiveness of uricosuric drugs decreases;
- Griseofulvin - absorption of acetylsalicylic acid is possible;
- GCS - increased risk of ulcerogenic effects and the occurrence of gastrointestinal bleeding;
- The effectiveness of diuretics (spirolactone, furosemide) decreases;
- Other NSAIDs increase the risk of side effects;
- Alcohol - an increased risk of gastrointestinal ulcers and bleeding;
- Inhibitors of serotonin reuptake - the risk of developing gastrointestinal bleeding increases;
- The concentrations of digoxin, barbiturates and lithium salts in blood plasma increase;
- Decreased efficacy of captopril and enalapril (with acetylsalicylic acid in high doses);
- Caffeine - increases the rate of absorption, plasma concentration and bioavailability of acetylsalicylic acid, the risk of adverse reactions;
- Inhibitors of platelet aggregation - an increased risk of bleeding.
Reviews
Practically all the comments about ASK are positive. The drug is inexpensive, effective, well-studied, has a wide range of applications. Tablets excellently remove inflammation and fever, and regular intake of ASA in small doses reduces the riskcardiovascular complicationsin predisposed patients.
Minuses of the drug are usually called potentially side effects. However, as most people note, in order to avoid them, during the treatment period, it is enough simply to follow certain rules: at least, Before taking the pill, you should carefully read the instructions and give up alcohol for the entire treatment period.
Analogues
Structural analogs for the active substance:
- Aspicor, Aspirin, Aspirin Cardio, Acecardol, Acetylsalicylic Acid, Cardi ASA, Cardiomagnet, Colfarit, Mikristin, Plolidol 100, Plolidol 300, Polokard, Taspir, Trombo ACC, Thrombogard 100, Trombopol, Uppsarin UPA.
Before using analogues, consult your doctor.
Aspirin and Analgin
Acetylsalicylic acid is aspirin or analgin? Aspirin is a derivative of salicylic acid. Acetylsalicylic acid, often called aspirin, was obtained by replacing one hydroxyl group. Therefore, analgin is a completely different drug.
Storage conditions and shelf life
Store at a temperature not exceeding 30 ° C in a place inaccessible to children.
Shelf life - 5 years. Do not use after the expiration date printed on the package.
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