Ibuprofen is an antipyretic, analgesic, anti-inflammatory drug.
Indications for use are various inflammatory processes caused by the action of inflammatory prostaglandins. The composition of the drug includes two complementary molecules that block negative modifications of metabolites of arachidonic acid.
On this page you will find all information about Ibuprofen: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ibuprofen tablets. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
NSAIDs.
Conditions of leave from pharmacies
Released without a doctor's prescription.
Price list
How much is Ibuprofen? The average price in pharmacies is at the level of25 rubles.
Form of issue and composition
Tablets Ibuprofen - round, smooth, biconvex white.
- Each tablet contains 200 mg or 400 mg of active ingredient.
- Auxiliary substances - magnesium stearate, talc, lactose, potato starch, silicon dioxide colloid, Povidone 25.
For 10, 20 and 100 pieces per pack.
Pharmacological effect
The active substance of the drug is ibuprofen, a derivative of phenylpropionic acid.
Ibuprofen is most effective for inflammatory pains. By antipyretic effect sufficiently close to acetylsalicylic acid. Suppresses the adhesion of platelets, improves microcirculation and reduces the intensity of inflammation. With external application Ibuprofen in the form of an ointment has a strong analgesic effect, reducing flushing, morning stiffness and swelling.
The drug is classified as one of the most important medicines of the World Health Organization, its effectiveness and safety has been studied and clinically tested.
Indications for use
What helps the pill Ibuprofen? The main indications for prescribing the drug are:
- Inflammatory diseases of the spine and joints (including rheumatic and rheumatoid arthritis, deforming osteoarthritis, ankylosing spondylitis, gouty arthritis).
- Moderate or weak pain syndrome of different origin (including migraine, headache, myalgia of non-rheumatic and rheumatic origin, toothache, postoperative pain, neuralgia, primary algodismenorea, sore throat and in the ears, posttraumatic pains).
- Feverish syndrome with infectious and "cold" diseases.
Contraindications
the NSAID from any manufacturer, for example, Ibuprofen Hemofarm instructions for use does not recommend that anyone suffering from any form of allergic reaction to its active ingredient, aspirin, should be admitted. When the body reacts in the form of bronchial, rhinitis, anaphylaxis spasm to any NSAID, Ibuprofen does not recommend using the instructions for use.
Do not take it in any form:
- during pregnancy;
- after bypass;
- at a hyperreaction of an organism on any component of the agent;
- with diseases of the blood system associated with a violation of its coagulation;
- with internal hemorrhages (especially intracranial) or suspicion of them;
- in diseases of the digestive system, accompanied by ulceration of its mucosa and perforation of ulcers;
- with progressive renal pathology, especially in chronic renal failure.
Age restrictions depend on the form of the drug. For example, children's suspension is not given to children under 3 years old. "Adult" forms of the drug can be administered to children from 6 years of age. Ibuprofen Akrikhin instructions for use in the form of suppositories does not recommend the use for treatment of babies up to 3 months.
Application in pregnancy and lactation
Ibuprofen is the drug of choice for pain and heat during pregnancy, because during this time period for the body of a woman he is safer than most other analgesics and antipyretics.
In the first 2 trimester of pregnancy, it does not adversely affect the development of the fetus, does not provoke bleeding (as opposed to aspirin) and does not create a threat of miscarriage.
Ibuprofen is contraindicated in the last trimester of pregnancy.
First, the drug inhibits the contraction of the musculature of the uterus. Secondly, its use can cause closure of Botallov duct and development of pulmonary hypertension in the child. Thirdly, the medicine has the property of blocking the hormones responsible for the generic process.
Ibuprofen during breastfeeding does not affect the quality and secretion of milk, so it can be used to treat lactating women.
Instructions for use
The instructions for use indicate that tablets should be swallowed by washing with water, preferably during or after a meal. Do not take more than 4 hours.
- Adults, seniors and children over 12 years of age: in tablets of 200 mg 3-4 times a day; in tablets of 400 mg 2-3 times a day. The daily dose is 1200 mg (do not take more than 6 tablets of 200 mg (or 3 tablets of 400 mg) for 24 hours.
- Children from 6 to 12 years (with a body weight of more than 20 kg): 1 tablet 200 mg not more than 4 times / day. The interval between taking the tablets is at least 6 hours.
The course of treatment without consulting a doctor should not exceed 5 days. If symptoms persist, consult a physician. Do not exceed the indicated dose!
Side effects
There are several side effects in different body spectra, which should be noted:
- common problems - fatigue and malaise;
- in the gastrointestinal tract - ulcer and intestinal disorders, flatulence, dyspepsia;
- immune function - hypersensitivity, asthma, anaphylaxis;
- kidney system - organ dysfunction, nephropathy and nephritis;
- blood and lymphatic system - leukopenia, thrombocytopenia, anemia;
- infectious nature - meningitis, rhinitis in the presence of autoimmune disorders;
- sensory organs - problems with sight, hearing, noise sensations, dizziness;
- cardiovascular activity - puffiness, problems with fluid retention, insufficiency;
- CNS - anxiety and sleep problems, prolonged depression, neuritis, pain in the head, a state of drowsiness.
Observance and consideration of these factors ensures a quick recovery. Information about the preparation ibuprofen, instruction on the use of the tablet, price, reviews, analogs are given for informational purposes.
Overdose
If the daily or single dose of Ibuprofen is exceeded, then the following symptoms occur:
- metabolic acidosis;
- coma;
- acute renal insufficiency;
- lowering of blood pressure;
- rapid or slow heart rate;
- pain in the abdomen, nausea, vomiting;
- drowsiness, drowsiness, depressive state;
- headache, tinnitus;
- atrial fibrillation and respiratory arrest.
With these conditions, treatment is applied:
- gastric lavage (effective within the first hour after taking the drug);
- Activated charcoal (used to reduce the absorption of medication in the gastrointestinal tract);
- alkaline drink and forced diuresis;
- symptomatic therapy (observe blood pressure, heart rate and general condition).
When the first measures are taken, it is necessary to seek qualified help and call an ambulance.
special instructions
- With long-term use, control of the peripheral blood picture and the functional state of the liver and kidneys is necessary.
- If it is necessary to determine 17-ketosteroids, the drug should be discontinued 48 hours before the test.
- To reduce the risk of developing adverse events from the gastrointestinal tract, the lowest effective dose should be used. When symptoms of gastropathy appear, careful monitoring including esophagogastroduodenoscopy, a blood test with determination of hemoglobin and hematocrit, and analysis of feces for latent blood are shown.
During the treatment period, one should refrain from drinking alcohol and activities that require an increased concentration of attention and speed of psychomotor reactions.
Drug Interactions
- Caffeine increases the analgesic effect of ibuprofen;
- When interacting with serotonin reuptake blockers, the risk of bleeding from the gastrointestinal tract increases;
- When treating with induction of microsomal oxidation, the risk of intoxication increases;
- Ibuprofen is not recommended with simultaneous treatment with other NSAIDs;
- At appointment with anticoagulants the risk of a bleeding increases;
- Barbiturates and preparations with ethanol increase the concentration of ibuprofen in blood plasma;
- Reduces the effects of vasodilators, furosemide and hydrochlorothiazide;
- Increases the activity of antiaggregants, indirect anticoagulants, fibrinolytic drugs, hypoglycemic drugs and insulin, sulfonylurea derivatives;
- With simultaneous treatment with cephalosporins, the frequency of hypoprothrombinemia increases, the risk of nephro- and hepatotoxic effects increases;
- Kolestyramin and antacids reduce the absorption of ibuprofen.
Reviews
We picked up some feedback from people about the Ibuprofen drug:
- Larissa. Earlier from pains in a stomach or belly used Nurofen by advice or council of the friend and me efficiency of a preparation completely arranged. Afterwards, the pharmacist advised in the pharmacy to take a more profitable and equally effective Ibuprofen. Since that time I drink it from headaches, menstrual pains, dental pains. The agent does not give me side effects.
- Igor. Ibuprofen, Paracetamol and other anti-inflammatory drugs help me equally well. The only difference between the first and the rest is the reaction rate. So, if you drink these pills, it becomes better after an hour. Paracetamol needs more time to act. At a price, both drugs are budgetary and available to anyone.
- Victor. Very strong drug. There was a temperature of 40, fever, delirium, put on his feet for 3 doses, but immediately it became clear that as a candy you can not eat him and treat as little as possible with the minimum dose. Also noticed his influence on perception, has a mild intoxicating effect, greatly soothes and leaves only pleasant memories of the reception (something like a narcotic effect, to control the machine after taking a little difficult). Personally, I noticeably hit the kidneys, and so for myself, I concluded that it must be washed down with plenty of water. Very pleased with the price and the ability to replace expensive drugs such as teraflu or pentaflucin. For myself, I made a choice, in the case of Orvi or influenza treatment will be treated with ibuprofen, it's worth it.
Find bad reviews about Ibuprofen in tablets, candles or syrup, perhaps, not. The drug is regarded as an effective and sufficiently safe means.
Its advantages are:
- low price;
- fast effect;
- the possibility of using for the treatment of pregnant women and children of any age;
a large number of dosage forms (this allows you to correctly select the minimum effective dose).
As a minus in the reviews, the presence of contraindications and the risk of developing side effects inherent in NSAIDs are usually mentioned.
Analogues
Analogues for the active ingredient are the following:
- Moment of 400;
- Advance;
- Nurofen;
- Ibuprom;
- Dolgit;
- Solpaflex;
- Ibuklin;
- Burana;
- Deblock.
Before using analogues, consult your doctor.
Storage conditions and shelf life
The drug is recommended to keep in places with a low level of humidity at a temperature not exceeding + 25 ° С.
Shelf life of tablet forms is 3 years. Keep away from children!
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