Structure instruction: on application

Instruction for the preparation Structum 500: indications for use, price, reviews

Diseases of the joints and spine develop, as a rule, after 40-50 years against the background of natural age changes. Less often - due to metabolic disorders in young people, as a result of occupational injuries and sports loads.

First of all, cartilaginous tissue is affected: arthroses and intervertebral hernias occur. Fortunately, modern medicine has effective chondroprotectors, among which the French drug Structum has proved itself well.

Price, instructions for use, patient reviews and analogues - later in the article.

Structum belongs to the group of chondroprotectors, i.e. it protects the joints from destruction (chondros - cartilage, protect - protect).

The main component of Structum is chondroitin (chondroitin sodium sulfate). Normally, the substance is produced in sufficient quantities inside the joint bag.

With its lack, the viscosity, density and the volume of joint fluid are reduced, the regeneration of tissues is slowed down - the cartilage deforms and collapses.

With age, the production of chondroitin decreases, and with increased loads, the normal amount may not be enough, and then an additional source is required.

The drug stimulates the regeneration and growth of cartilage, inhibits the processes of their destruction.

• Due to the synthesis of hyaluronic acid it normalizes the density, viscosity and volume of the joint fluid.
• Promotes the accumulation and retention of calcium in bone tissue, thereby restoring it.
• Stimulates the active growth of cartilaginous tissue.
• It removes local inflammation, reduces pain, and returns mobility to the organ.

Forms of issue

It is registered as a medicinal product and is manufactured by the French company Pierre Fabre Medicament Production in capsules of 250 and 500 mg in blisters or bottles:

• 250 mg - 100, 60 or 30 pieces / pack;
• 500 mg - 60 pieces / pack.

Despite the fact that the medicine is released without a prescription, its reception should be agreed with the doctor in advance.

Structum is appointed as an independent agent or as part of complex therapy for the treatment of diseases and pathological conditions:

• osteoarthritis;
• osteochondrosis;
• osteoporosis;
• injury during the rehabilitation period.

Contra-indications and limitations

• Intolerance to the components of the drug or gelatin shell.
• Age is less than 15 years.

According to the instructions, it is not recommended to use the drug during pregnancy and lactation.

Patients with bleeding should be used with caution.

In rare cases, Structum can cause skin allergic reactions, vomiting or nausea.

Overdose is possible with a single use of a large amount of the drug or after a long reception, when the daily dose exceeds 3 g per day.

Symptoms:

• disorders of the digestive tract - diarrhea, nausea, vomiting;
• hemorrhagic rash.

Method of application and duration of treatment

The drug should be taken orally 500 mg 2 times a day in the morning and in the evening, with a sufficient amount of water - a capsule of Structum 500 mg or 2 250 mg at a time.

The duration of the first course of treatment with the drug is at least six months.

For a month, 60 capsules of Structum 500 mg or 120 capsules of 250 mg are enough.

The therapeutic effect persists for a long time, so a second course should be discussed with your doctor. The manufacturer guarantees a curative effect for 3-5 months after cancellation, in fact, the period is determined individually by the patient's condition.

Average prices in Russian pharmacies

The cost of the drug Structum depends not only on the form of release, but also on the wholesale and retail margins of the network in which the medicine is purchased. The spread of prices can reach several hundred rubles.

• Structum 500 mg (60 units / pack) - from 1500 to 2000 rubles;
• Structum 250 mg (60 units / pack.) - from 900 to 1500 rubles.

The means by which a drug can be substituted are divided into two groups:

1. synonyms (otherwise called generics), drugs with the same active substance and dosage;
2. analogs, which, in addition to chondroitin, contain other active components (for example, glucosamine).

Synonyms

Chondroitin sulfate.
Under such an international name, a drug with a 250 and 500 mg active ingredient is produced by Russian manufacturers. From Structum is different only at a lower price (1000-1500 rubles.); a month's course is cheaper than a French equivalent.

It is also sold in ampoules of 100 mg for injections. Chondroxide (Russia).
Tablets 250 mg in packages of 30-100 pcs. from the company Nizhpharm. The only disadvantage of this synonym is that 500 mg is not convenient for taking a dosage; however, it is more than offset by a favorable price of 450-500 rubles.

for packing 60 pcs.

Analogues

Kondronov (India).

Tablets with 200 mg of chondroitin and 250 mg of glucosamine. Because of the reduced dosage, the drug will have to be taken according to the instructions for 2 tablets 2-3 times a day. The average price is 350-450 rubles. for packing 30 tab., which is enough for a week. Artra (France).

It is characterized by an increased dosage of active ingredients - 500 mg of chondroitin and 500 mg of glucosamine. The cost is 1400-1600 for 60 capsules. Teraflex (USA).
Contains 400 mg of chondroitin and 500 mg of glucosamine, which also protects the cartilage tissue and promotes its regeneration.

Since the drug is not synonymous with Structum, the choice should be agreed with the attending physician in advance.

Instruction for use recommends taking Teraflex twice a day on a capsule (in the first 3 weeks a three-time appointment is given). The price is 1500-1800 rubles. for 100 capsules.

Complex dietary supplements with chondroitin for athletes are produced in the USA and Europe under different brands: Cybermass, Weider, Ultimate Nutrition, etc.

They can be bought in pharmacies and specialized stores, determining for themselves the optimal dosage of the active substance.

Accepted biologically active supplements to support joints under high loads, but not for treatment.

Choosing a cost-effective analogue of the Structum 500, you need to read the instructions for use, study reviews those patients who have already taken similar drugs and choose the optimal daily dosage recommended by doctor.

Reviews about the drug

Anna, 30 years old.

"There was a serious knee injury, damaged the meniscus. The doctor appointed Structum 500 for the restoration of cartilage.

Saw 3 months, every morning and before going to bed, did not notice any pobochek. Cartilage, indeed, began to grow rapidly from the first weeks, as shown by the X-ray.

The drug is effective, I recommend. "

Vera Ivanovna, 63 years old.

"Structum is a good medicine, with it I almost do not remember problems with joints, but for pensioners it turns out expensive if you drink it constantly.

I switched to domestic Chondroitin, and did not notice any difference. Helps the same, the instructions are no different, the indications for use are the same, and at a price - several times cheaper.

Now I'm buying only him. "

Maxim, 35 years old.

"A couple of years ago, my back ached. Has passed or has taken place inspection, have found an intervertebral hernia. The doctor prescribed physiotherapy, swimming and Structum 500. I took two times for six months, as a result, the back does not bother at all! "

Maria, 45 years old.

"I suffer from arthrosis of the joints of the foot. It is not treated, and it is necessary to maintain and protect the joints all the time, so that the disease does not progress. Periodically I drink courses Structum 500 (3 times a year). It helps! For two years, the pain decreased, now with the loads they almost do not feel. "

Igor Nikolayevich, 68 years old.

"I have been suffering from osteochondrosis for about ten years. On the advice of a doctor, he once took Structum 500, hoping for relief.

I do not advise anyone. "

A source: http://pomogispine.com/lechenie/lekarstva/struktum.html

Structure: Instructions for use

The drug Structum represents a pharmacological group of medicines, drugs regulating metabolic processes in the cartilaginous tissue, as well as protecting it from negative effects (chondroprotectors). It is used to treat various pathologies of the structures of the musculoskeletal system, accompanied by damage to the cartilaginous tissue.

Composition and form of release

The drug Structum is manufactured in a dosage form gelatin capsules for oral administration (oral administration).

They have a casing of blue color, the contents are in the form of a powder of whitish cream coloring, small sizes (size No. 0).

The main active ingredient of the drug is chondroitin sulfate in the form of a sodium salt, its content in one capsule is 500 mg. It also includes auxiliary substances, which include:

• Carmine indigo.
• Gelatin.
• Titanium dioxide.

Capsules of Structum are packaged in a blister of 12 pieces. Cardboard pack contains 5 blisters with capsules (60 capsules), as well as instructions for using the drug.

Pharmacodynamics and pharmacokinetics

The main active component of capsules Structum chondroitin regulates metabolic processes (metabolic processes) in tissues of hyaline and fibrous cartilage.

It stimulates synthetic processes, in particular the formation of glycosaminoglycans, which are the main structural component of the intercellular substance of the cartilaginous tissue.

Due to this, the drug reduces the intensity of the course of degenerative processes, accompanied by damage to the cells and intercellular substance of the cartilaginous tissue.

To a lesser extent chondroitin influences the metabolic processes in bone tissue, it promotes its speedy recovery, and also reduces the severity of resorption (leaching) of calcium salts, imparting strength to the mineral matrix. Due to such biological effects, this drug has a protective effect on the cartilaginous tissue (chondroprotective effect), and also reduces the severity of the inflammatory reaction.

After taking the capsule of Structum, the active ingredient inside is fast enough and is absorbed into the systemic bloodstream 70% from the intestinal lumen by 70%. Chondroitin is evenly distributed in tissues, followed by accumulation in cartilage and bone. Partly it is excreted in the urine by the kidneys.

Indications for use

Receiving capsules Structum is indicated as a means of pathogenetic therapy (treatment aimed at reducing the severity of manifestations pathological process due to the restoration of the functional state of the cartilage and bone tissue) diseases accompanied by malnutrition and destruction of cartilaginous tissue (degenerative-degenerative processes) - osteochondrosis, osteoarthritis with localization in any joints.

Contraindications for use

Absolute medical contraindication to the reception of capsules of Structum is an individual intolerance any of the components of the drug, which mainly leads to the development of an allergic reaction. Also, the drug is not used in patients under the age of 15, since its safety and effectiveness for children remain unproven.

Dosing and Administration

Capsules of Structum are intended for oral administration. They are taken whole, without chewing and drinking with a sufficient amount of water.

The average therapeutic dosage and regimen for adults and adolescents over 15 years is 50 mg (1 capsule) 2 times a day. The duration of the initial course of therapy should be at least six months.

If necessary, after a certain period of time, the course of treatment can be reassigned, while its duration and regime application of the medicinal product the doctor sets individually, depending on the degree of severity, the effectiveness of the previous course of therapy.

Side effects

Against the background of taking the drug capsule Structum, it is possible to develop negative pathological reactions from various organs and systems, these include:

• The digestive system - nausea, accompanied by periodic vomiting.
• Allergic reactions - a rash on the skin, its itching, characteristic changes resembling a nettle burn (hives), the appearance of red spots (erythema).

If adverse side effects occur, the capsules should be discontinued and consult a medical professional who will determine whether to continue the course of therapy.

special instructions

Before taking capsules Structum, it is important to carefully read the instructions to the drug. There are several specific indications that should be taken into consideration during the application of this medication, including:

• With special care under medical supervision, as well as laboratory monitoring of the functional state coagulating system of blood (hemostasis) the drug is used in individuals with concomitant disorders of formation a thrombus.
• The active ingredient of capsules of Structum can enhance the therapeutic effects of drugs of the pharmacological group with indirect coagulants, fibrinolytic and antiplatelet agents, therefore, when combined, medical supervision and laboratory monitoring of the functional state hemostasis.
• Since there is no reliable, reliable data on the safety of this drug on the body of a developing fetus and an infant, its use for pregnant and lactating women is not recommended.
• The active component of this drug does not directly affect the nervous system, so against its background employment is allowed to engage in work, coupled with the need for sufficient concentration and speed of psychomotor reactions.

In the pharmacy chain, Structum capsules are dispensed without a doctor's prescription. If there is any doubt about the use of this medication, it is recommended that you consult with a medical professional.

Overdose

If there is a significant one-time excess of the recommended therapeutic dose of Structum capsules, nausea, vomiting, and diarrhea may develop.

In case the taken dose exceeds 3 g, there may be a pinpoint bleeding in the skin (hemorrhagic rashes).

In such cases, washing of the stomach, intestines, intake of intestinal sorbents (activated charcoal), as well as symptomatic therapy in a hospital are performed.

Analogues of Structum capsules

Similar in composition and therapeutic effect for the capsules of Structum are the preparations Artradol, Mukosat, Hondroguard.

Terms and conditions of storage

The shelf life of capsules of Structum is 3 years. They must be stored in intact original packaging, dark, dry, inaccessible to children at an air temperature of not more than + 25 ° C.

Structure price

The average cost of packing Structum capsules (60 capsules) in pharmacies in Moscow varies between 1419-1735 rubles.

A source: http://bezboleznej.ru/struktum

What helps Structum? Instructions for use, price, analogues

A drug of anti-inflammatory and chondroprotective action is Structum. Instructions for use indicate that the drug regulates the metabolism in the cartilage tissue, stimulates their regeneration. From what tablets Strutkum help you can learn from the instructions.

Form of issue and composition

The drug is produced in the form of capsules of 250 and 500 mg. Tablets, as a form of release, are not used in the manufacture of the drug.

Structum 500 mg is available for 12 capsules in blisters.

One capsule of Structum, the instruction for use reports this, contains an active substance - chondroitin sodium sulfate 250 mg or 500 mg.

pharmachologic effect

Chondroitin sodium sulfate, the main active ingredient of Structum, is a complex-structured mucopolysaccharide belonging to the group of glycosaminoglycans. Chondroitin sulfate is obtained from the cartilage of the trachea of ​​healthy young chickens by deep purification and fermentation.

Most analogues of Structum contain chondroitin with a lower degree of sulfation.

It is due to the high degree of sulfidity of chondroitin contained in the Structome that this substance is capable of attracting and retaining the maximum permissible amount of liquid in the cartilage. Thanks to this, the elasticity and elasticity of the cartilage in the joints increases.

Pharmacological market today provides a large number of different chondroprotectors, but it is in Structum that the structure of chondroitin has the greatest similarity with the human.

In addition, the chondroitin contained in Structome has the lowest molecular weight in comparison with active substance of analogues of Structum, due to this, he operatively penetrates through synovial shell. The accumulation of chondroitin in the synovial membrane allows for a certain time to nourish and restore cartilaginous tissue in the joints.

In addition, chondroitin normalizes the structure of hyaluronic acid, since it is the main component for its formation.

In turn, quality hyaluronic acid reduces the friction of the joint surfaces by lubricating them.

Due to this effective complex effect, this drug has a stronger therapeutic effect on joints in comparison with the analogues of Structum, contributing to their fastest recovery.

After taking the drug more than 70 percent of it is absorbed in the digestive tract. The maximum concentration in blood plasma is observed after 3-4 hours, in synovial fluid - after 4-5 hours. Bioavailability is about 13%.

Tablets Structum: what helps the medicine

Indications for use include:

• parodontopathy;
• osteoarthrosis and other degenerative-dystrophic diseases of the spine and joints;
• osteoporosis;
• fractures (for more rapid formation of bone callus);
• intervertebral osteochondrosis.

Contraindications according to the instructions

Drug Structum instructions for use prohibit taking in the following cases:

• thrombophlebitis;
• bleeding and a tendency to bleeding;
• hypersensitivity to the ingredients of the drug Structum, from which tablets can cause allergies;
• the period of pregnancy and breastfeeding (due to insufficient data);
• children's age till 15 years (as there are no exact data on safety and efficacy of the drug);
• the period of lactation.

Structum preparation: instructions for use

Apply Structum is allowed to patients older than 15 years. Adults and adolescents begin taking the drug from a dosage of 1 g per day (500 mg 2 times a day).

The duration of treatment is usually 6 months. The therapeutic effect of the drug persists for 3-5 months after the end of the course of treatment.

If necessary, repeated courses can be appointed, the duration of which is determined individually. Apply Structum only orally, capsules should be washed down with water.

After the beginning of the use of Structum, the therapeutic effect is felt not immediately, but in a few weeks, since time must pass for the accumulation of chondroitin in the synovial fluid. It should be taken into account that the metabolic process in bone-cartilaginous tissues does not proceed as intensely.

However, after a long course of treatment, patients will still feel the positive effect of the drug for many more months.

Adverse Events

The medicine can cause in some cases:

1. nausea;
2. vomiting;
3. urticaria;
4. itching.

Interaction

If the drug is used simultaneously with indirect anticoagulants, fibrinolytics and antiaggregants, the effect of the latter is enhanced.

At pregnancy and thoracal feeding

Structum is not recommended for use during pregnancy and lactation (breastfeeding) because of the lack of sufficient clinical data.

Analogues of the drug Structum

The identical active substance is analogous:

• Chondroxide.
• Mukosat.
• Chondrolon.
• Chondroitin sodium sulfate.
• Artradol.
• Hondrogaard.
• Kartilag Vitrum.
• Artra Chondroitin.
• Arthrin.
• Chondroitin.
• Honsurid.

To the preparations intended for therapy of an arthrosis, carry analogues:

1. Coxib.
2. Dona.
3. Orthophene.
4. Arthra.
5. Rheumatic Gel.
6. Dicclore.
7. Triamsinolone.
8. Gumisol.
9. Dexamethasone phosphate.
10. Diphene.
11. Piroxicam.
12. Brufen.
13. Terfalex.
14. Aktasulid.
15. Picture Composite.
16. Rumalon.
17. Kenalog.
18. An arthrovitis.
19. Dicluberl.
20. Alflutop.
21. Voltaren Emulgel.
22. Brufen retard.
23. Fastum gel.
24. Cigapan.
25. Chondrolon.
26. Ibuprofen.
27. Diclofenac.
28. Nimesil.
29. Sabelnik Evalar.
30. Elderin.
31. RONIDASE.
32. Donalgin.
33. The Unium.
34. Ketonal.
35. Indomethacin.
36. Diprospan.
37. Mesulide.
38. Glucosamine sulfate.
39. Naproxen.

Which is better: Arthra or Structum?

Based on the comparison of the formulations, it can be concluded that the effect of Arthra is more complex, since it contains additionally glucosamine, which protects the cartilaginous tissue from various damage. In other respects, it is worth remembering that injectable drugs have greater bioavailability, and the treatment of joint pathology should be multicomponent.

Price

Tablets Structum buy in Moscow can be for 1600 rubles. The price of the drug in Kiev and Ukrainian cities is 750 hryvnia. In Minsk, pharmacies offer to buy a remedy for 64-90 bel. rubles. In Kazakhstan, it costs 8830 tenge.

Reviews

About the structure of opinion are not fundamentally different from reviews about other drugs of identical composition.

Forums containing reviews of patients about Structum, say that chondroitin drugs are most effective as part of a comprehensive treatment, including procedures that enhance blood supply and treatment gymnastics.

The doctors' testimonies testify to the greater effectiveness of injecting preparations before other forms of release (tablets and capsules).

"It's amazing, but after taking capsules, my joints started to ache more."

"I've been taking it for almost a month, the pain and clicking have gone away. I think after the course of admission I will forget for a long time about my joints. "

"I drank this chondroprotector together with an artron flex glucosamine 750 mg for 6 months. Parallel nyxes alflutop, mowali, imalin. The result is satisfied. "

"Positive dynamics appeared already during the first course of admission - somewhere in a month of admission became to note the greater mobility of the joints, which allowed me to more actively engage in physical exercises. "

"The drug really works, and really, it helps. The only thing that depresses is the fact that the price of Structum continues to creep up, in connection with which, I plan to return to Piaskledin no less than time-tested. "

"Do not rely entirely on the" magic "capsule - it is necessary in the literal sense to do your physical and start with at least a small walk, and who has the opportunity, then resort to massage. This is an important and necessary feature of the application of any chondroprotector. "

A source: http://remedy.ucoz.ru/index/struktum_instrukcija_po_primeneniju_analogi_cena_ot_chego_pomogaet/0-509

Structum (500 mg): instructions for use of the drug and its analogues

• Action of the medicine
• Indications and contraindications for use
• Form release of the drug. Mode of application
• Efficiency
• Prices and reviews
• Analogues and reviews

To date, the problem of locomotor system diseases has become urgent. Unfortunately, they affect not only the elderly, but also young people.

Therefore, new drugs are being developed to eliminate such problems. One of such medicines is "Structum".

Instructions for use, reviews and price are given below.

Effect of the drug

Tablets "Structum" refer to a group of chondroprotectors, that is, means that protect cartilage and joints from destruction.

This effect is due to the content of the substance chondroitin sulfate in the preparation, namely its main active ingredient - sodium salt.

It should be noted that chondroitin is practically the basis of cartilaginous tissue, so it is extremely important for the normal state of cartilage.

Another action of the drug is stimulation of the synthesis of hyaluronic acid, which is responsible for the normal viscosity of the synovial fluid (and this liquid also has a direct effect on the state cartilage). There is also an antiseptic effect of chondroitin, which helps fight inflammation of the tissue.

Indications for use, contraindications and side effects

In what cases is the drug "Structum" shown? It can help with certain diseases of the musculoskeletal system. It is worth mentioning some of them:

1. arthrosis (in particular, primary);
2. osteoarthritis of large joints;
3. osteoarthritis of the spine;
4. intervertebral osteochondrosis;
5. osteochondrosis of the joints;
6. other diseases of joints and spine of a degenerative-dystrophic nature.

Now for contraindications. Here is their list:

• phlebitis and thrombophlebitis;
• pregnancy;
• the period of breastfeeding;
• age up to 15 years (no data on the use of the drug by people of this age group);
• bleeding of any kind and inclination to them;
• hypersensitivity to certain components and substances of the drug.

As for side effects, they arise in rare cases, but still have a place to be.

Most often, the receiving medication has digestive disorders: nausea, flatulence, sometimes diarrhea, or, on the contrary, constipation.

If the patient is inclined to allergic reactions, then he may have a rash or slight edema. In all these cases, the drug should be discontinued.

Form of release and method of use

The drug is produced in three dosage forms: in the form of capsules of blue color with a volume of 500 mg ("Structum 500 ") and 250 mg (" Structum 250 "), in the form of film-coated tablets, as well as in the form of a solution for injections.

How and in what doses is it worth taking the drug? This should tell the attending physician after a thorough examination. But more often doctors recommend taking 1 capsule of the drug (500 mg) twice a day.From the reception of food the application does not depend.

Swallow the capsule whole, not chewing and squeezed with enough water.

Sometimes in the first three weeks of the course the patient should take 1500 mg per day (it is better to divide the dose twice and take two capsules at once: 500 mg and 250 mg at the same time). Then the daily dose can be reduced to 500 mg.

Now about injections. The solution is injected intramuscularly in, mg at a time. Nips are done every other day. if the tolerance of the drug is good, then the doctor can double the dose. usually the course of treatment includes 25-35 injections. Repeated therapy can be prescribed in six months.

Effectiveness of the drug

When can we expect the effect of using the product? The main substance is perfectly absorbed in the intestine and enters the blood after 3-4 hours.

And its main goal, namely cartilage and synovial fluid components reach about 5 hours later. It is there that the drug will accumulate.

And given this most cumulative effect, it can be noted thatChanges will be observed only after 3-4 weeks (sometimes later) after the application is started.But the effect persists for a long time.

In the next 5-7 months, the substances will still be contained in the cartilage, then gradually begin to be removed from there (and then the treatment will need to be repeated).

Prices and reviews

What is the price of "Structum" tablets? They cost about 1000 rubles (for 60 tablets of 500 mg). Approximately the same value have capsules (the number and volumes are the same).

As for ampoules with a solution for injection, they can be purchased for about the same price. You can buy the drug in any pharmacy, and also order online.

It is worth noting that prices can vary (in the range of 100-200 rubles).

Now reviews of patients about the drug "Structum". We offer to familiarize with some of them:

Appealed to the doctor, he advised "Structum" and the course of massage. After 4 months, I actually saw the results. But it is unclear what exactly helped: massage or medicine.

I think that the integrated approach played a role. "

And here is what Albina writes: "For a long time I suffer from osteochondrosis of the thoracic and cervical spine. The doctor advised "Structum". I drank it for six months, but I saw absolutely no results. "

Maria: "I have osteoarthritis of the hip joint, which really hinders me from living. What only I did not try! And then the doctor offered to try to start the reception of "Structum". I drank it for 5 months and realized that I live a normal life.

The doctor said that I was in a small percentage of patients to whom this drug actually helps so much that all the symptoms of the disease disappear. "

Physicians refer to the drug rather skeptically, but still often it is prescribed as an additional therapy.

Drug analogues

There are some analogues of the drug "Structum". Their first group as the main substance also contains chondroitin sulfate. These are preparations such as: "Chondrolon "Chondroxide "Chondroitin "Mukosat "Structonin "Artrotsels" and others.

The second group of analogues in the composition has not only chondroitin sulfate, but also glucosamine, which also has a positive effect on the joints. To such means it is possible to carry: "Teraflex "Artra" and others.

And the third group of analogs contains natural components, namely concentrates of cartilaginous tissue of sea fish and animals, as well as extracts of soybeans. Let us list such medicines: Aflutop, Piaskladin, Rumalon.

Which is better: "Structum" or "Teraflex"? Even a doctor can not answer this question, because everything depends on the individual, his illness and the body's response to the components of the remedy. So you can find out everything only by experience.

Health to you!

A source: https://vashaspina.ru/struktum-500mg-instrukciya-po-primeneniyu-preparata-i-ego-analogi/

Structum - instructions for use, analogues, reviews, price

Structum is a drug that improves the process of restoring the cartilaginous tissue and normalizes the metabolism in it.

Active substance

Chondroitin Sulfate Sodium.

Form of issue and composition

Structum is produced in the form of gelatin capsules of light blue color. Inside the capsules there is a white-cream fine powder, in which small lumps (conglomerates) can be contained. Capsules of 250 and 500 mg are on sale.

Structum, capsules	1 capsule
Chondroitin Sodium Sulphate	250 or 500 mg
Auxiliary components: talc, gelatin, indigo carmine, titanium dioxide (for making a capsule shell).

Indications for use

The drug is recommended for the treatment of degenerative diseases of the spine and joints - arthropathies, osteoporosis, osteochondrosis (spine).

Contraindications, dosage

Structum is not assigned for individual intolerance to its components. The drug is contraindicated in the presence of thrombophlebitis.

Instructions for use Structum (method and dosage)

Adults and children over 15 years old start taking the drug at a dosage of 1 g per day (500 mg 2 times a day). The duration of treatment is usually 6 months.

The therapeutic effect of the drug persists for 3-5 months after the end of the course of treatment.

If necessary, repeated courses can be appointed, the duration of which is determined individually.

Apply Structum only orally, capsules should be washed down with water.

After the beginning of the use of the drug, the therapeutic effect is felt not immediately, but in a few weeks, since time must pass for the accumulation of chondroitin in the synovial fluid.

The exchange process in bone-cartilaginous tissues proceeds not very intensively.

However, after a long course of treatment, patients will still feel the positive effect of the drug for many more months.

Side effects

Often, the drug is well tolerated by most patients without causing side effects. However, sometimes allergic reaction, nausea and vomiting can develop.

Overdose

Overdosing occurs if the prescribed dosage is exceeded for 3 or more days. Symptoms: nausea, vomiting, diarrhea, hemorrhagic eruptions. Symptomatic treatment is performed.

Analogs of Structum

To the analogues of Structum are the following medicines: Arthron Khondreks, Structonin, Mukosat, Chondroguard, Cartilag Vitrum, Arthrin, Chondroitin Sulphate, Chondroxide (gel, ointment, tablets), Honsurid, Chondrolon. Nimulid, Diacerein, Aponil, Sigan, Arthron Khondreks.

pharmachologic effect

Chondroitin sodium sulfate, the main active ingredient of Structum, is a complex-structured mucopolysaccharide belonging to the group of glycosaminoglycans. Chondroitin sulfate is obtained from the cartilage of the trachea of ​​healthy young chickens by deep purification and fermentation.

Most analogues of Structum contain chondroitin with a lower degree of sulfation.

It is due to the high degree of sulfonation of chondroitin contained in the preparation that this substance is capable of attracting and retaining the maximum permissible amount of liquid in the cartilage. Thanks to this, the elasticity and elasticity of the cartilage in the joints increases.

Pharmacological market today provides a large number of different chondroprotectors, but it is in Structum that the structure of chondroitin has the greatest similarity with the human.

The accumulation of chondroitin in the synovial membrane allows for a certain time to nourish and restore cartilaginous tissue in the joints.

Chondroitin normalizes the structure of hyaluronic acid, since it is the main component for its formation. At the same time, high-quality hyaluronic acid reduces the friction of the joint surfaces by lubricating them.

Due to this effective complex effect, this drug has a stronger therapeutic effect on joints in comparison with the analogues of Structum, contributing to their fastest recovery.

The drug inhibits the process of bone resorption, activates their healing, for example, in fractures, and also reduces the withdrawal of calcium from the body in case of osteoporosis.

When taking the drug, the original thickness of the cartilage remains, due to which the shock of the joints is better absorbed. The pharmacodynamics of this drug has been studied in detail.

Absorbed Structum with oral intake of up to 70%, the maximum flow into the blood is observed after 3-4 hours, and into the joint fluid after 4-5 hours. The drug is characterized by low bioavailability, which is only 13%.

Such indicators are achieved mainly due to the complex structure of the chondroitin molecule. The process of removing the drug from the body is performed by the organs of the urinary system.

special instructions

Very carefully Structum is prescribed for patients with increased bleeding of various origins.

At pregnancy and thoracal feeding

The drug intake during pregnancy and during lactation is contraindicated.

In childhood

Apply Structum to children over 15 years of age.

In old age

Information is absent.

Drug Interactions

Simultaneous reception of Structum with other drugs can enhance the effect of indirect anticoagulants, fibrinolytics and antiplatelet agents.

Conditions of leave from pharmacies

They are released by prescription.

Terms and conditions of storage

Keep out of the reach of children. The temperature should not exceed + 25 ° C. Shelf life - 3 years.

Price in pharmacies

The price of Structum is 60 capsules of 500 mg starting at , 97 rubles.

A source: http://dolgojit.net/struktum.php

Instructions for the use of the drug Structum and its analogs with prices and reviews

Structum is a drug for the treatment of diseases of the musculoskeletal system. Its action is aimed at regulating and restoring metabolic processes in the cartilaginous tissue.

The testimonies indicate that the course of treatment with a medicine helps to eliminate the symptoms of joint damage, as a result, their functioning becomes better.

Consider how the structure works, what indications and contraindications to its use exist, as well as average prices.

Description

The drug is available in the form of capsules for oral administration. The active ingredient is chondroitin sulfate, and also auxiliary components are included.

Given the quantitative content of the active component, Structum is available in two dosage versions. These are gelatin capsules 250 and 500 mg each. Outwardly they are blue, inside is a white or creamy powder.

The drug has an effect on the joints, and in particular on the cartilaginous tissue. This effect is that this composition causes the following effects:

• Stimulation of regeneration.
• Anti-inflammatory effect.
• Anesthetic effect.
• Chondrostimulation.
• Decreased calcium loss.
• Slowing of bone resorption and activation of the processes of its restoration.
• Reduction of pain syndrome.
• Increase the mobility of articular surfaces relative to each other and increase the volume of movements in them.
• Suppression of interleukin-1beta, which has a negative effect on the structure of the cartilage.
• Activation of the production of proteoglycans, hyaluronic acid.
• Prevention of compaction of cartilaginous tissue.

That is, as a result of metabolic transformations, Structum stimulates the formation and development of the main cells of the cartilaginous tissue - chondrocytes.

The composition of the drug helps to retain the liquid. This increases the elasticity of the cartilage, and its damping function is performed better.

This effect is confirmed by the feedback.

However, the composition of the agent affects not only the cellular elements. The drug improves the formation of intercellular substance of the cartilaginous tissue. Improvement of cartilage nutrition is caused by stimulation of intraarticular fluid formation.

When recommended and not recommended

The instruction is recommended for use in the following cases:

1. Arthritis.
2. Osteoarthritis.
3. Osteoporosis.
4. Traumatic damage to the elements of the musculoskeletal system.
5. Osteochondrosis.
6. Spondylosis.

Contraindications include individual intolerance of the components that make up the drug. Also, Structum should not be administered to children under 15 years of age.

This is due to the fact that no significant clinical studies on its use in children have been conducted.

A similar situation is observed with regard to pregnant women and breastfeeding women. In connection with this, it is not recommended to take a drug of this category of patients.

Method of use

Instructions for use recommend taking Structum in a daily dose of 1 g. That is, if it is a capsule with a dosage of 500 mg, it will be optimal to take one pill in the morning and one in the evening. The reviews point out that such a method of application is quite convenient.

The duration of the course of treatment is usually about six months. However, only the doctor can determine the optimal daily dosage, the frequency and duration of the drug.

It is worth noting that the positive effect can persist for 3 or even 5 months after the completion of the course of therapy. If necessary, the doctor may prescribe a second course of treatment.

But the reviews say that, as a rule, one course is enough.

With caution should be used medicine for people with a tendency to bleeding. It is also important to remember that the drug is able to enhance the effect of anticoagulants, antiplatelet agents and fibrinolytic agents.

Since the main component of the agent is a natural component of the structural elements of the joint, the development of side effects is rare.

And even if they arise, their severity is small, and they disappear after the drug is discontinued. Against the background of the application, allergic reactions may occur in the form of urticaria, pruritus, dermatitis.

Rarely there are such dyspeptic disorders as nausea.

Cost and similar means

In the pharmacy you can find analogues of the drug. The most famous tablet form is Dona, Teraflex. Their composition is similar. Reviews note that some of them are cheaper, respectively, are more affordable.

It is difficult to unequivocally determine which medicine is better from the proposed ones. Feedback indicates the good effectiveness of such drugs. And this is not surprising, because they have a similar composition and mechanism of action. The table shows the price of the most popular analogs.

Preparation and analogues	Price
Structum 250 mg, No. 60	1200 rubles.
Structum 500 mg, No. 60	1500 rubles.
Dona 750 mg tablets, No. 60	1800 rub.
Teraflex Capsule No. 30	600 rubles.
Teraflex Capsule No. 60	1300 rub.
Teraflex Capsule No. 100	2000 rub.

Structum has established itself as a drug for the treatment of various joint diseases. It is quite easy to apply the medicine. The most important thing is that the course of treatment can be carried out at home.

The composition of the remedy allows to restore the function of the joints, and this removes many limitations and makes the quality of life better. The patients' comments point out that the effectiveness and simplicity of the instructions for use makes it possible to make adherence to treatment better.

And even the price is not an obstacle to treatment.

A source: http://ProKoksartroz.ru/preparaty/struktum