Neurox

Neurox is a drug that is used as an antioxidant to improve blood flow in the brain, antidepressant and anticonvulsant effects on the body.

The drug has a stabilizing effect on the body after stressful situations. It is used for ONMI, TBI, with encephalopathy, MI, for personality disorders and other diseases of the nervous system.

It is produced by the Russian pharmacological company Sotex. The drug has become widespread because of the large list of indications for use, the small number of serious adverse reactions and the low probability of overdose.

Clinical and pharmacological group

Antioxidant drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Neurox cost in pharmacies? The average price is at the level of310 rubles.

Form of issue and composition

Dosage form - solution for intravenous and intramuscular administration: slightly yellowish or colorless, transparent (in ampoules of 2 or 5 ml, 5 ampoules in outline cell packaging, 1, 2, 4 or 10 packages are placed in a cardboard bundle; in ampoules of 10 or 20 ml, in contour cell packs of 1 ampoule, 1 carton is placed in a cardboard bundle).

instagram viewer

Composition of 1 ml of solution:

active substance: ethylmethyl hydroxypyridine succinate 50 mg;
additional components: sodium disulfite - 1 mg; water for injection - up to 1 ml.

Pharmacological effect

Pharmacological group - nootropic, antioxidant, anticonvulsant drugs. The active substance has a variety of mechanisms of action on the body, especially on nerve tissue, heart muscle.

Pharmacological actions: prevention of seizures;

improvement of mental processes;
antidepressant properties;
increase of resistance of the organism to negative influences of negative factors (ethanol, shock, intoxication);
improvement of blood properties, decrease in the probability of thrombus formation;
inhibition of lipid peroxidation (antioxidant properties);
protection of cell membranes, in particular neurons;
elimination and prevention of tissue hypoxia;
protection of the nervous system from the negative effects of stress;
stimulation of blood flow in the brain;
decreased LDL levels (anti-atherogenic properties);
normalization of metabolic processes in the heart muscle, especially in ischemia (with infarction).

Indications for use

Indications for Neurox are:

anxiety disorders accompanying neurotic and neurosis-like conditions;
abstinent alcoholic syndrome, characterized by a predominance of vegetative-vascular and neurosis-like disorders (for cupping purposes);
primary open-angle glaucoma of various stages (in combination with other drugs);
encephalopathy;
disorders of cerebral circulation of the acute course (as part of combined treatment);
craniocerebral trauma and the resulting disorders;
acute myocardial infarction (appointed from the first day in combination with other drugs);
syndrome of vegetative (neurocirculatory) dystonia;
cognitive disorders of the atherosclerotic nature of the lung course;
acute intoxication with antipsychotics (antipsychotic drugs).

Contraindications

Neuroks can not be used in the following diseases and conditions:

pregnancy and breast-feeding;
increased sensitivity of the organism to the components of the drug;
severe diseases accompanied by acute impairment of kidney or liver function (acute renal and hepatic insufficiency);
children of any age.

With caution Neurox is used for allergic diseases and reactions that the patient had in the past. During treatment, you should be careful when driving a car and doing other jobs that require increased concentration and speed of response.

Dosage and route of administration

In the instructions for use, it is indicated that Neurox is injected with V / m or I / in (jet or drip). With the infusion method of administration, the drug should be diluted in 0.9% sodium chloride solution.

With the infusion method of administration, the drug should be diluted in 0.9% sodium chloride solution. Jet Neurox injected slowly for 5-7 minutes, drip - at a speed of 40-60 drops per minute. The maximum daily dose should not exceed 1200 mg.

In acute intoxication with antipsychotic drugs, the drug is administered IV in a dose of 200-500 mg / day for 7-14 days.
With abstinence alcohol syndrome Neuroks injected in / m or / in the drip in a dose of 200-500 mg 2-3 times a day for 5-7 days.
With open-angle glaucoma of various stages as part of complex therapy, Neurox is administered in / m at 100-300 mg / day, 1-3 times / day for 14 days.
With neurocirculatory dystonia, neurotic and neurosis-like conditions, the drug is administered in / m at 50-400 mg / day for 14 days.
In acute violations of the circulatory blood circulation Neuroks used in complex therapy in the first 10-14 days - in / in the drip for 200-500 mg 2-4 times / day, then - in / m 200-250 mg 2-3 times / day for 2 weeks.
For mild cognitive impairment in elderly patients and with anxiety disorders, the drug is used in / m at a dose of 100-300 mg / day for 14-30 days.
In case of craniocerebral trauma and consequences of craniocerebral traumas, Neuroks is used for 10-15 days IV infusion of 200-500 mg 2-4 times / day.
In dyscirculatory encephalopathy in the phase of decompensation, Neurox should be administered intravenously or in droplet at a dose of 200-500 mg 1-2 times / day for 14 days. Then - in / m at 100-250 mg / day for the next 2 weeks.
For the course of prophylaxis of dyscirculatory encephalopathy, Neurox is administered at a dose of 200-250 mg 2 times / day for 10-14 days.
With acute myocardial infarction as part of complex therapy, Neurox is administered iv or I / m for 14 days, against a background
traditional therapy of myocardial infarction (including nitrates, beta-adrenoblockers, ACE inhibitors, thrombolytics, anticoagulant and antiaggregant drugs, as well as symptomatic drugs according to indications). In the first 5 days Neurox is administered intravenously, in the following 9 days the drug can be injected / m.

Side effects

In most cases, the drug is well tolerated by patients, but in individuals with increased individual sensitivity, the following side effects may occur:

Fat in the body;
Pershenie in the pharynx and in the nose;
Chest pain, lack of air;
Dryness in the mouth and appearance of an unpleasant aftertaste with a "metallic" hue.

With prolonged use of the drug appears nausea, bloating, sleep disturbance, irritability.

People with a high risk of allergic reactions can develop severe skin rashes, angioedema, anaphylactic shock.

Overdose

In case of an overdose, there may be insomnia or, on the contrary, drowsiness. If the drug is administered intravenously, a slight increase in blood pressure (BP) is possible within 90 to 120 minutes after administration. After this time, the symptoms of BP come to normal on their own, the state of health is restored within a day.

When insomnia is sometimes prescribed drugs from the tranquilizers (for example, Diazepam) in the minimum dosage.

special instructions

During the period of treatment, patients should be careful when driving and other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Drug Interactions

Strengthens the action of benzodiazepine anxiolytics, antiepileptic (carbamazepine), antiparkinsonian (levodopa) drugs, nitrates.

Reduces the toxic effects of ethanol.

Reviews

We picked up some reviews of people who used Neurox:

Larissa. During an attack, she only took 2 ml. slowly, but the headache after it is terrible. But the attack was removed, Which attack???? I do not know if it's Simpato-adrenal crises or Astheno Neurotic or??? But such attacks. that the end of the world seems to have come. Mexidol is better tolerated and relieves seizures. And Neurox is probably better suited for torture.
Valentina. Has appointed or nominated the neurologist from a noise in a head of 10 nyxes / m, but the hum has amplified and the pressure which is difficult for knocking down by habitual preparations raises, the head splits. I did not fit.
Nastya. The husband suffered an ischemic stroke. Several rehabilitation courses passed, but there were mild neurological disorders, anxiety. The polyclinic was prescribed this drug. They injected intramuscularly, after a week of treatment, noticed positive improvements. There are several ampoules left, we will continue to be treated.