Ambene analogue, composition and indications for the use of drugs

"Ambene analogue, instructions for use, feedback

"Ambene" is a complex action drug intended for intramuscular administration. This product is suitable for the treatment of diseases in which the nervous system and joints are affected.

Components of the medicine, acting on the body, effectively fight with microbes, relieve pain, eliminate heat, stop inflammatory processes. Let's consider more in detail the drug Ambene.

Composition, analogs, reviews, instructions are described in the article.

The medication is available in the form of ampoules and in syringes. The preparation includes two ampoules, each containing different substances. Each is applied separately, making deep intramuscular injections.

Analog "Ambene injections of the original drug have a similar effect. Previously, the drug was issued in the form of two solutions with different composition (A and B), which needed to be combined among themselves.

In the first composition of Ambene there were components that render antipyretic, analgesic and anti-inflammatory hormonal action (dexamethasone, lidocaine, phenylbutazone, saliciamidacetate sodium). The second solution consisted of lidocaine and vitamin B12.

Currently, the drug is produced, in the ampoules of which both compounds are already connected.

pharmachologic effect

Effectively removes inflammation, with virtually no side effects after using the drug Ambene. The analog works the same way.

Phenylbutazone - NSAID, due to which pain goes away, heat is removed, diuretic and anti-inflammatory effects are provided. Salicylic amide acetate also has analgesic properties, its presence in the formulation contributes to better dissolution of the components.

Vitamin B12 is necessary for the normal implementation of metabolic processes in which nucleic acids and lipids participate.

Vitamin allows to remove the degenerative changes that occurred in the tissue due to the disease (neuritis, osteochondrosis).

Lidocaine provides a painless introduction of the drug. All the components that are present in the Amben are perfectly combined and strengthen each other's action.

Since the medicine has a powerful effect on the body, it is administered in small doses.

The analogue of the drug "Ambene" has in its composition other substances, but their effect is directed to achieve the same result, which completely allows you to replace the original with the appearance of such a necessity.

Indications for use

The drug treats joint diseases in an acute form and neurological diseases, which also occur acutely.

It is suitable for the treatment of osteochondrosis, arthritis, spondylitis, gout, arthrosis, can be used with radiculitis and in the treatment of a condition such as neuralgia.

This tool relieves pain in the presence of changes in the spine, which occurred due to degenerative processes. "Ambien" eliminates the unspecified joint pains and the symptoms that accompany their injuries.

Short-term treatment of acute conditions occurs using the drug "Ambene analogs. The reviews show that both types of therapy can be successfully implemented.

The choice of medicines is individual, what does not fit one person, can help to cope with the problem to another.

When hypersensitivity to the components of "Ambien" and other contraindications, the doctor chooses the most suitable analogue.

Contraindications

Taking medication is prohibited in many cases, since corticosteroids often have a large number of contraindications. Do not always allow the reception of "Ambien" instructions for use. Analogues in this case will replace the original and will have the same effect.

For example, "Ambene" is not prescribed for systemic mycosis and lupus erythematosus, with herpes, lymphadenitis, chickenpox.

Contraindications are poliomyelitis, mumps, acute gastritis, pancreatitis, ulcer, some disorders heart activity, as well as violations in the thyroid gland, serious violations in the functioning of the liver and kidney.

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The drug is not suitable for use in cases of excessive sensitivity to its components, planning of vaccination and after it. To the list of contraindications are stomatitis, glaucoma, myasthenia gravis.

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You can not use Ambene with Sjogren's syndrome, bearing a child and breastfeeding it. Children under the age of 14 and elderly people are prescribed an analogue of the drug Ambene. You should make a choice in favor of another remedy after the surgery.

Use of the drug, dosage

By applying the medicine "Ambien" pain sensations of an acute nature that are present in the joints are eliminated. This drug allows you to conduct short-term treatment courses aimed at eliminating pain in the spine and neuritis.

Usually, patients are prescribed a drug for use at an interval of one day. However, it can not be used more than 3 times in one week.

"Ambene the analogs are pricked with strict adherence to the instructions. If necessary, repeat the course when the doctor says.

It usually takes place a few weeks after the completion of the first course.

It is very important to make an injection correctly. The drug is injected deeply and slowly. Thus the patient should be in a lying position. Do not inject into another position. If the package includes two ampoules, first a solution of A is drawn into the syringe, followed by solution B.

Side effects

"Ambene analogs, generics are capable of causing some side effects. For example, violations of the functioning of the digestive tract, changes in the formula of blood, anemia.

There may be manifestations of allergic reactions, a decrease in blood pressure, a general deterioration in well-being, lack of sleep or a bad sleep, the appearance of a headache and other side effects.

As the reviews show, the human body rarely responds to the drug with negative reactions. Complications arise if the drug is used for a long time or without strict adherence to the instructions.

The place where the injection was done can be painful. In addition, it is possible to develop inflammatory processes in the tissues and their necrosis.

If undesirable reactions are noted on the part of the body, hemodialysis, artificial ventilation of the lungs and other measures aimed at improving the patient's well-being are required. In the most severe cases, the use of the drug "Diazepam" is required, it is administered intravenously.

special instructions

The medicine "Ambene analogs of this remedy, have in their instructions special instructions that should be taken into account before starting treatment.

Vitamin, present in the "Ambien is able to change the picture of blood, when it is checked by people, suffering from anemia, and phenylbutazone - to influence the results of the analysis when testing the thyroid glands.

Care is needed in the presence of certain diseases, their presence should be discussed with the attending physician.

Drug Interactions

"Ambene analogues of the medicine are combined not with all means.

This drug interferes with the normal action of oral contraceptives, it negatively affects the effect of medications that can reduce blood pressure, inhibits the action of "Sulfinpyrazona." When combined, the toxic effect of Methotrexate is enhanced.

The action of "Ambene" weakened by "Rifampicin" and barbiturates, anabolic steroids - on the contrary. The combination of anti-inflammatory drugs is very dangerous for health, as is the use of alcohol during the treatment period.

If necessary, take another remedy with the medicine "Ambene" should consult a doctor.

Analogues and cost of the drug, reviews

The basic information about the drug "Ambene instructions for use, price, reviews, analogs allow you to choose the most suitable method of treatment. Its price is an average of 5 thousand. rub.

The analogue of "Milgamma" is the closest to the original preparation. Depending on the indications, the doctor can prescribe together with this substitute "Dexamethasone and with "Movalis" - "Neurobion".

As an analogue, an infiltration blockade based on "Lidocaine" and "Dexamethasone" can be applied, but only on the appointment of a specialist.

As patients report, a positive result of treatment appears quickly enough. Judging by the reviews, the main advantage of "Ambene" is its quick action.

This drug sometimes helps very much, especially when there are no other ways to eliminate the negative symptoms of the disease, but it needs to be done as quickly as possible.

In general, the medication is effective, but both some doctors and buyers believe that the substitutes are no worse.

A source: http://.ru/article/218895/ambene-analog-instruktsiya-po-primeneniyu-otzyivyi

Ambien

Composition of Ambien

The composition of the drug, issued in ampoules or syringes contains:

• 2 ml of solution №1 mgdexamethasone, 4 mglidocaine hydrochloride, 50 mgsodium hydroxide, 375 mgphenylbutazone, water for injections,sodium salicylamide;
• 1 ml of solution №2 - 2 mglidocaine hydrochloride mgcyanocobalamin, purified water.

Form of issue

Ambene is produced in double ampoules of dark glass, in cardboard packages of 3 or 10 pieces.

Also, the drug is sold in syringes with two chambers, in packages of 3 or 10 syringes.

pharmachologic effect

Anesthetic, anti-inflammatory, uricosuric, antipyretic action.

Pharmacodynamics and pharmacokinetics

The action of the drug is due to its constituent components.

Dexamethasone-glucocorticoid, which has a pronouncedanti-inflammatoryaction.

Getting into the body, the substance interacts with specific receptors, penetrates into the nucleus of the cell, affects the formationmRNA.

Thus, the process of protein formation changesribosomes, especiallylipoprotein, responsible for the formation of specific responses of the body to inflammatory processes,allergyetc. Mediators of inflammation cease to stand out frommast cellsandeosinophils. This substance is practically absentmineralocorticoidactivity.

Lidocaine hydrochlorideanesthesia locally, during the injection of the drug into the muscle, the patient practically does not feel pain.

PhenylbutazoneNon-steroidal anti-inflammatory agent, is a derivativepyrazolone. Reduces body temperature, anesthetizes and relieves inflammation. Possessesuricosuriceffect.

Cyanocobalamin- a vitamin Bhematopoietic, metabolicandantianemic action.

The substance is involved in lipid and carbohydrate metabolism, regeneration of nerve cells, is a part ofnucleic acids, is able to strengthenanalgesic effectfacilities.

Salicylamide sodiumanesthetizes and improves the solubility of the drug.

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Due to the fact that the components of the agent mutually reinforce each other, the dosage of dexamethasone can be significantly reduced.

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The drug still has a long shelf life. The medicine can be stored for so long due to the fact that solutions No. 1 and No. 2 are separated from each other.

After the injection was injected intramuscularly, the active substances quickly enter the systemic circulation.

Phenylbutazonebinds well to plasma proteins and penetrates the placenta, has the property of excreted in breast milk.Metabolismis slow. Half-life is about three hours.

Indications for use

Ambene is appointed:

Contraindications

The injections are contraindicated:

• atallergies, on any of the components of the medicine;
• elderly patients;
• with violations in the work of the kidneys, liver,thyroid gland;
• patients suffering fromgastritis, stomach ulcer;
• atmyasthenia gravis, myelosuppression, Sjogren's syndrome;
• atheart failure, arrhythmiasandmyocardial infarction;
• if the patient is infected with a virusherpes, mumps, poliomyelitis, chicken pox;
• when developinglymphadenitisafter the introduction of the vaccineBCG;
• pregnant and lactating women;
• at the systemmycosis, glaucoma, myopathies;
• sicksystemic lupus erythematosus, temporal arteritis, stomatitis;
• athemorrhagic diathesis, pancreatitis,
• in the period before (2 months) and after (14 days)vaccination;
• children under 14 years;
• after surgical interventions.

Side effects

During the administration of the drug, the following side effects may develop:

• headache, insomnia, disturbance of the psyche, hearing or sight;
• anorexia, nausea and vomiting,diarrhea, gastralegia, increased levels of hepatic enzymes, bleeding and damage can rarely occurGIT;
• itching on the skin,fever, Lyell's syndromeorStevens-Johnson, bronchospasm;
• agranulocytosis, leukopenia, pancytopenia, decreaseHELL, thrombocytopenia.

Rarely possible:mycosis, decreaseimmunity, abscessand pain at the injection site,sialadenitis, Isenko-Cushing syndrome, lymphadenopathy.

Instructions for use Ambene (Method and dosage)

As a rule, the medicine is prescribed for 1 injection per day. Injections are made every day or every other day, but not more often 3 times a week.

If there is a need for another course, you should wait a few days.

The injections are made intramuscularly, deeply, slowly. The drug in the syringe should be first recruited from ampoule A, then from B.

Instructions for use Ambene in a syringe

• Remove the protective rubber cap from the end of the syringe, put the needle provided with the syringe on it.
• Slowly move the piston until the first drop appears on the end of the needle, with both chambers with the solution in the syringe to be mixed.
• The drug should be administered immediately after the procedures described above.
• The temperature of the solution should be of the order of 36-37 degrees.

Overdose

In case of an overdose, adverse reactions can be significantly increased, up to the statecoma.

As therapy is shownartificial ventilation, various resuscitation measures,antiepileptic drugs(eg,Diazepam), hemodialysis.

Interaction

You can not inject the funds 2 months before or 14 days after vaccination.

The drug reduces the effect of drugs that lowerHELL.

When combined with otherNSAIDsand means containing alcohol, the probability of bleeding andperforationsatGIT.

Combined reception Ambene withsulfonamidesandlithium preparationscan increase plasma concentrations of the latter.

When the drug is combined with derivativessulfonylureasandinsulinmay develophyperglycemiaorhypoglycemia.

The product significantly increases toxicityMethotrexateandPhenytoin.

With simultaneous administration of the drug withanticoagulants of indirect action, Dipyridamole, Heparin, sulfinpyrazoneIt is necessary to adjust the dosage of the products, depending on thePTI.

Drug enhances sleeping pillsbarbiturates.

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The drug should be gently combined with variouscardiac glycosides, it can slow down or on the contrary speed updigitalizationpatients.

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Ambien in combination withdiureticscan lead to the development ofhyperkalemia, reducediuresisandsodium syrup.

The medicine is not recommended to be combined withoral contraceptives, due to a decrease in their effectiveness.

The effect of the drug is enhancedmethylphenidateandanabolic steroid.

Terms of sale

You need a prescription.

Storage conditions

Keep the drug in its original packaging, in a dark, cool place. Keep away from children.

Shelf life

36 months.

special instructions

If you want to investigate the functionthyroid gland, then you can carry out the tests not earlier than 14 days after the end of treatment with the drug.

Analogues of Ambien

There are no structural analogues of the preparation. Instead of the drug, doctors are most often prescribed:Milgamma, Movalis, Neurobion, Dexamethasoneand injectionsLidocainein various combinations.

In pregnancy and lactation

The drug is not prescribed forof pregnancy. During the reception of the fundslactationit is recommended to stop.

Reviews about Amben

On the Internet they write mostly good reviews about Amben, the medicine quickly and permanently suppresses the pain syndrome and relieves inflammation. Side effects with respect to the intake and dosage regimen do not occur.

Price Ambienne

You can buy the medicine for about 600-800 rubles, for 1 ampoule.

How much does it cost to buy Ambene in Moscow?

The price of injections Ambene is about 860 rubles per ampoule.

NOTE! Information about medicines on the site is a reference-generalizing, collected from public sources and can not serve as a basis for making a decision about the use of medications in the course of treatment. Before applying Ambene, always consult with your doctor.

A source: http://medside.ru/ambene

Ambien

Ambene belongs to the group of non-steroidal anti-inflammatory drugs in combination with glucocorticosteroids.

Form of issue and composition

The drug is available as a solution for intramuscular injection. It is located in double ampoules of type A and B. In one package contains 3 or 10 pieces of ampoules of each kind. Also included is a syringe with two chambers for each solution, a napkin and a patch.

The composition of Ambene solution A (volume - 2 ml):

• , 2 mg dexamethasone;
• 4 mg of lidocaine hydrochloride;
• 375 mg of phenylbutazone;
• 4, 8 mg of sodium hydroxide;
• 150 mg of sodium salicylamide acetate;
• 167, 2 mg of water for injection.

In solution B (volume - 1 ml) contains:

• , mg of cyanocobalamin;
• 2 mg of lidocaine hydrochloride;
• 99, mg water for injection.

Indications for use Ambien

The use of Ambene is effective in the short-term therapy of acute conditions caused by joint inflammation (arthritis), osteoarthritis, radiculitis, neuralgia, degenerative diseases of the spine, accompanied by a violation of the structure of the tissue and severe pain syndrome, athletic injuries.

Contraindications

Refuse the use of the drug recommended to persons with hypersensitivity to NSAIDs, acute gastritis, duodenal ulcer and stomach, acute myocardial infarction, other diseases of the myocardium, accompanied by conduction disorders, chronic heart failure in the phase decompensation. Also, according to the instructions to Ambene, the medication is not suitable for patients with severe impairment of kidney, thyroid or liver function. In addition, contraindications are:

• Viral infections, including chicken pox, poliomyelitis, herpes;
• Glaucoma, myopathy, Sjogren's syndrome, myasthenia gravis;
• Systemic mycosis;
• Systemic lupus erythematosus, temporal arteritis, hemorrhagic diathesis, rheumatic polymyalgia;
• Stomatitis, pancreatitis;
• Lymphadenitis associated with the introduction of BCG, a period of 2 months before and 2 weeks after vaccination;
• Surgical interventions;
• Breastfeeding, pregnancy;
• The elderly age and age is less than 14 years.

Method of application and dosage Amben

Ambene solution should be administered intramuscularly, deep into the gluteus muscle. It is recommended to observe the frequency of no more than 3 injections in 7 days, one injection every day or every other day. The interval between the two courses should not be less than a few weeks.

To obtain an injectable solution, first draw liquid from ampoule A, then from ampoule B.

Side effects of Ambien

The use of Ambene can affect the work of the nervous system, causing excitement, dizziness, sleep disturbance, headache. In rare cases - mental disorders, hearing and hearing disorders.

From the cardiovascular system may appear leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, aplastic anemia, there is less evidence of hypotension and orthostatic collapse.

Reactions from the digestive system can manifest as anorexia, gastralgia, nausea, ulcerogenic effect, diarrhea, vomiting, less often - in violations of liver function and bleeding of the gastrointestinal tract.

Among other adverse reactions are noted: mycosis, pain in the area of ​​injection, Isenko-Kuschchyna syndrome, renal dysfunction, sialoadenitis, abscess, decreased immunity, lymphadenopathy.

special instructions

In connection with the fact that phenylbutazone, which is part of Amben, affects the function of the thyroid gland, Analyzes associated with its study are conducted no earlier than 2 weeks after discontinuation of therapy with the help of Ambien.

In addition, due to the content of cyanocobalamin in the drug, the use of Ambene can distort clinical and laboratory parameters in patients with pernicious anemia and funicular myelosis.

Ambene should be taken with caution to patients with impaired renal function, with diabetes, tuberculosis, epilepsy, bronchial asthma, mental disorders, lung diseases in chronic form, bronchial asthma, amoebiasis, bacterial infections in acute or chronic phase.

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It is recommended to treat with a minimum dose of the drug in order to avoid the development of negative reactions.

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Injections are administered under completely sterile conditions. To prevent the appearance of irritation at the injection site, the needle should be inserted deeply into different areas.

For the time of treatment Ambien is recommended to adjust the diet of patients in such a way that food is supplied protein, potassium, vitamins in the right amount, while it is necessary to reduce the intake of carbohydrates, fats and culinary salt.

Analogues of Ambien

Currently, there is no description of drugs, the mechanism of action and composition of which is similar to the mechanism of action and composition of Ambien.

Terms and conditions of storage

The drug is stored for no more than three years in a place protected from light, where the temperature does not reach 25 ° C.

A source: http://spraa03.net/ambene.html

Ambien: description of the drug, principle of action and effectiveness

For the treatment of diseases of the musculoskeletal system of man, there are many different drugs.

Modern medicines are able to exert a complex effect on pathological conditions, due to which the effectiveness of treatment increases and the patient quickly recovers.

One of such medicines is Ambene (Ambene).

The drug copes well with diseases that affect the peripheral nervous system and joints.

Ambene acts on pathology in several directions at once.

This is due to the presence of five active components in the drug, in particular:

• dexamethasone, which removes the inflammatory process;
• lidocaine hydrochloride, relieving pain;
• phenylbutazone, which removes heat and swelling of tissues;
• sodium acetate salicylamide, which improves the solubility of the drug;
• cyanocobalamin (vitamin B12), which promotes the regeneration of nerve cells and improves lipid metabolism.

The active substances are dissolved in distilled water.

Form of issue

German company Merckle produces Ambene in the form of two solutions for injections in ampoules, which are labeled as A and B.

Ampoules contain a different composition of the substances listed above. Preparations are mixed with each other only before introduction into the muscle.

Paired ampoules are packed in cardboard boxes of three or ten pieces.

The medication can be purchased in syringes, which have two chambers for different formulations. The syringes are packed in boxes of three or nine pieces.

One tablet contains 200 mg of sodium phenylbutazone.

The drug has anti-inflammatory, antipyretic, uricosuric and analgesic properties.

Dexamethasone refers to glucocorticoids - steroid hormones that actively suppress inflammatory processes.

Due to the action of this substance, mast cells stop producing mediators of inflammation.

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Phenylbutazone, as well as the first substance, fights inflammatory processes. He is a member of the group of nonsteroidal anti-inflammatory drugs (NSAIDs).

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Vitamin B12 supplements the action of Ambien with the normalization of metabolic processes affecting the nerve fibers, and restores the nerve tissue.

This component is used to eliminate degenerative tissue changes in osteochondrosis, neuritis, etc.

Lidocaine allows injections to be painless. Salicylamide sodium acetate also acts as an anesthetic, and also promotes rapid solubility of the drug.

Due to this, the dose of steroid hormone is significantly reduced, and the desired effect is preserved.

Pharmacokinetics

Active substances easily enter the systemic circulation and are able to overcome the placental barrier, so the drug begins to act after the injection almost immediately.

The metabolism of the drug is slow, providing a lasting therapeutic effect. Substances begin to be excreted from the body after seven to eight hours.

The drug leaves the body with urine, feces, breast milk.

The drug is widely used to eliminate inflammatory phenomena in the musculoskeletal system, as well as in neuralgia. The medicine can be used in tablets, but in acute processes, the most effective are injections of Ambien, as they quickly eliminate the severe pain syndrome.

Indications for use

Medication is often prescribed for the treatment of various joint diseases - arthritis, gout, spondylitis, rheumatism, osteoarthritis, as well as with degenerative disorders in the spine.

Ambien injections are suitable for the treatment of neuralgic diseases, pain syndromes in the joints of unexplained etiology, dorsalgia, lesions of the brachial and lumbosacral plexus.

The drug is used in the case of sports or other injuries, which are accompanied by acute pain. Ambene injections are done during the rehabilitation period after surgery on the joints or spine.

Contraindications

The medication is great for the treatment of joints, however, Ambene has a complex formula and is not suitable for everyone.

The drug can not be used in the presence of the following pathologies:

• glaucoma;
• systemic lupus erythematosus;
• hemorrhagic diathesis;
• severe pathologies of the heart, kidneys, liver;
• gastritis;
• myasthenia gravis;
• pancreatitis;
• disorders in the thyroid gland;
• myopathy;
• temporal arteritis;
• zaaminellosis;
• dry Sjogren's syndrome;
• stomatitis;
• ulcers in the digestive tract;
• myelosuppression;
• viral infections;
• rheumatic polymyalgia.

In addition to this pathology, Ambien injections do not make pregnant and lactating women, children under the age of fourteen, elderly people.

The drug can not be used during the vaccination (two months before the procedure and fourteen days after the introduction of the vaccine), with the risk of developing allergic reactions to the components of the drug (bronchospasm, urticaria, etc.), hypersensitivity to drugs and surgical interventions.

Ambien injections can cause disorders in various organs and systems of the body, in particular:

• On the part of the gastrointestinal tract the patient may experience diarrhea, nausea, vomiting, bleeding from the gastrointestinal tract, the development of hemorrhagic pancreatitis.
• In a cardiovascular system, failures can be expressed by lowering the pressure.
• The patient may suffer from various allergic manifestations, from rashes on the skin, to acute spasm of the bronchi.
• Possible negative changes in the blood system, in the form of development of leukopenia, thrombocytopenia, anemia and a number of other pathologies.
• The patient may have headaches, dizziness, sleep, hearing, vision and psyche.
• Other side effects include suppression of immunity, sialadenitis, hypercortisy, lymphadenopathy, impaired renal function.

Treatment with Ambene should be carried out strictly according to the instructions. To exclude negative reactions of the body, therapy should be carried out under the supervision of a doctor.

In some cases, you may need to adjust the dosage of the drug. For pills and injections, there are treatment regimens that must be followed scrupulously. Let us consider them in more detail.

Ampoules

Doing injections with Ambene's medicine can be done only three times in seven days.

Usually the medication is administered after 24 hours, but daily injections are allowed, but not more than three. If the pain does not pass, then the doctor must prescribe another medicine.

Do not exceed the indicated dosage, as this is fraught with the development of serious pathologies.

The duration of therapy is determined individually by the attending physician. Ambene (medication in ampoules) is syringed one by one, first from ampoule A, then from B.

If injections are acquired in syringes, the medicine is mixed in them by moving the piston towards the needle. Before injecting, the solution should be heated to body temperature (approximately).

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During the procedure, the patient should assume a supine position. Injection is done slowly, deep into the muscle.

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Tablets are swallowed without chewing, and washed down with water. On the first day, it is permissible to take three tablets, and in the following days they drink one tablet in the morning and in the evening, with the same interval of time. Treatment is carried out for seven to ten days.

Overdose

If you do not comply with the dosage restrictions Ambene, the patient runs the risk of serious bodily harm.

A person who has exceeded the dose may suffer from headaches, dizziness, dyspnea, vomiting, bradycardia, renal or hepatic insufficiency, mental disorders, lowering blood pressure, pulmonary edema, seizures. In severe cases, the patient falls into a coma.

Interaction

Ambien is a medicine that must be combined very carefully with other medicines, since it has a significant effect on the action of various substances. It can not be combined with other anti-inflammatory drugs containing ethanol, as this can lead to bleeding from the digestive tract.

For the same reason, during the treatment it is forbidden to drink alcoholic beverages. To bleeding can also lead simultaneous reception of Ambene medication with anticoagulants.

When combined with methotrexate and phenytoin, Ambene enhances the toxic effect of these drugs, and when taking with barbiturates - a hypnotic effect.

With admission with diuretics, a potassium deficiency in the blood can develop. Anabolic steroids increase the therapeutic effect of Ambien, and inductors of microsomal liver enzymes - reduce.

Ambene should be used cautiously (preferably only under the supervision of a doctor) for people who suffer from diabetes mellitus, chronic lung diseases, epilepsy, hay fever, bronchial asthma, hypertension or hypotension, bacterial infections, thromboembolism, mental disorders, tuberculosis, osteoporosis, amebiasis.

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During the course of treatment, the patient needs to adjust the diet - include in the diet products rich in protein, vitamins and potassium, to exclude or significantly limit salt intake. Older and weakened people who have chronic diseases, it is necessary to reduce the dosage of Ambene medication as much as possible.

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A physician should select the individual therapy regimen. If side effects appeared in the form of fever, allergic reactions, and fecal masses turned to dark color, then the drug should be discontinued. Long-term treatment should only take place with the permission of the doctor.

In this case, it is necessary to monitor the work of the liver, kidneys and the state of peripheral blood. If the patient takes anticoagulants, then you should periodically take tests for coagulability.

Ambene: analogues, drug substitutes and patient reviews

If there are no contraindications to admission and the dosage of Ambene is observed, then the drug is tolerated well.

But what if you can not apply Ambien?Analogues, drug substitutes are best chosen together with a doctor, since other medicines contain a number of contraindications.

Replace the drug is also necessary in case of side effects. There are no structural analogs and substitutes for Ambene, no other preparation has such a composition of active components. However, according to the curative effect, you can choose a variety of medications.

Ambene can be replaced by Milgamma, Rumalon, Deximethasone, Artiflex, Nerobion, Lidocaine, Don, Movalis.

It is also useful to read reviews of patients about therapy with one or another drug.

Patients leave a lot of positive feedback about the drug Ambien. People note a rapid analgesic effect, especially in the joints.

Some patients write that this drug is very effective in treating diseases of different parts of the spine. Reviews of adverse events are rare.

Basically, patients are unhappy with the fact that it is difficult to buy medicines in Russia, especially in remote regions.

Price

Ambene, like its analogs (substitutes) can be found in online pharmacies in Russia or order an original drug in Germany - the country of the manufacturer.

In large cities, courier delivery is carried out, and the medicinal product is sent to the regions by cash on delivery. The price of the medicine varies depending on the number of ampoules, the form of the drug and the seller's price tag.

Ambene is not a cheap medication, the average prices in online pharmacies are as follows:

• Ampoules in the amount of 10 pieces - from 5000 rubles;
• Tablets in the amount of 50 pcs - from , 00 rubles.

Storage conditions and shelf life

Ampoules must be stored at a temperature not exceeding twenty-five degrees. It is inadmissible to get the drug into the hands of children. The shelf life of Ambene is three years.

A source: http://med88.ru/preparaty-dlja-sustavov/ambene/

Ambene injections - instructions for use, price, reviews and what are they for?

Diseases of the musculoskeletal system are very common these days, which must be eliminated in any way.

To relieve unpleasant symptoms in diseases of the nervous system and joints, Ambene is used - the drug complex effect, the effect of which is due to the pronounced antipyretic, anti-inflammatory effect.

Components that are part of the medicine are aimed at fighting microbes, removing heat, pain, etc. Ambene belongs to the category of combined drugs, it can be called an emergency aid for various ailments.

Form of release, composition and packaging

Ambien injections are administered intramuscularly.Issued in the form of a solution, the package contains 6 double ampoules with a solution of 1 and 2 ml.

In addition, the preparation can additionally be completed with a syringe of colorless glass and a patch made of PVC.

A unique feature of this drug is that two solutions are combined before administration.

So, let's consider what active substances form the basis of the drug Ambien?

1. Dexamethasone.The first component, which is a hormone-glucocorticoid. Characterized by a pronounced persistent anti-inflammatory effect. Side effects are minimized.
2. Phenylbutazone.It refers to the number of non-steroidal anti-inflammatory drugs that relieve pain and fever. It is important to note the bright diuretic effect.
3. Salicylamide-o-acetate sodium.It is important to emphasize the analgesic property of this component, which, in combination with other components, contributes to their better dissolution.
4. Vitamin B12.It allows successfully overcome such diseases as neuritis and osteochondrosis. In addition, it favors the treatment of degenerative changes in the nervous tissue.
5. Lidocaine.It helps to minimize pain when the drug is administered. In this way, the transfer is much easier and, most importantly, painless.

Cost

The price of the drug varies depending on the region. Not less important is the pharmacy network and other characteristics. To get this drug is incredibly difficult, it is rare in our country, so the price of it reaches fabulous marks.

Packaging, which includes10 ampoules, will cost a resident of Russia approximatelyin 4000-6000 rubles. Agree, not so cheap! If you have not met this drug in a pharmacy, it is recommended to contact a company that purchases medicines in Germany.

Ambene injections - pharmacology and description

The amazing effect of the miracle means is due to the substances in the Ambene. Inflammation inhibits dexamethasone. "Glucocorticoid assistant" after the adherence to the sections of the cell membrane. Then the medicine keeps the way to the nucleus and affects the synthesis of RNA.

It is because of this that protein synthesis undergoes transformation. itprovides a decrease in the level of proteins in the blood.

The activity of excretion of inflammatory mediators is significantly reduced.

The main purpose of non-steroidal components is to calm acute pain and lower the temperature.

The benefits of vitamin supplements in Ambene are in the prevention of anemia.

Indications for use

It is recommended to use the medication for patients who have joint diseases in an acute form. These include neurological ailments, which can lead to acute side effects.

The use of injections "Ambene" will be successful for patient patients:

• Gout;
• Osteochondrosis;
• Osteoarthritis;
• Arthritis;
• Spondylitis;
• Radiculitis.

Thanks to injections, the pain sensations localized in the spine are successfully removed. The effect of the drug is due to the fact that it depresses the pains in the joints.

Contraindications

In some cases, the drug may be harmful because of the presence of corticosteroids in the Ambene.

So, the drug is strictly prohibited for people who have the following diseases and conditions:

1. Pancreatitis.
2. Acute form of gastritis.
3. The ailments of the cardiovascular system.
4. Failure in the functioning of the thyroid gland.
5. Ulcer disease of duodenum.
6. Acute disorders in the work of the kidneys and liver.
7. Parotitis, poliomyelitis.
8. The launched form of myocardial infarction.
9. Sjogren's syndrome.
10. Glaucoma.

Do not advise to apply the drug Ambene to childrenunder 14 years of age.

In addition, it is strictly forbidden to use the medicine for women in an "interesting" position, as well as nursing mothers and the elderly.

If you have recently survived the operation, then you should also avoid using Ambene, giving your choice in favor of its counterpart.

Mode of application

It is important to pay a visit to a doctorthat he correctly appointed the frequency of injections, relying on the individual characteristics of the patient. Single injections, which are carried out every day, are the most popular. In rare cases, resort to the option of introducing a solution every other day.

The course of treatment consists of three intramuscular injections.If necessary, a qualified doctor may prescribe an additional course.

Before making the injection, a solution is prepared.To do this, first dial solution A in a syringe, then add it with solution B. Then, with a slight movement of pressure on the piston, the solution in the syringe is mixed.

It is important to know! The solution should be stored under temperature conditions that are as close as possible to body temperature.

Side effects

It is worth remembering that the nervous system can react quite sharplyon the introduction of an "unfamiliar" substance inside.

The use of Ambene is fraught with the appearance of complications of a negative nature if the drug has been used for a rather long time and was incorrectly injected.

In view of the use of injections, the following adverse reactions may follow from the body:

1. Deterioration of general condition.
2. Disturbances in the work of the digestive tract.
3. Headache.
4. Psychosis.
5. Insomnia.

In addition, the body can respond to the injected drug with vomiting, diarrhea, loss of appetite. In the hematopoietic system, changes in the composition of blood cells can be observed, as well as their ratio. Under the influence of the drug, a sharp decrease in blood pressure is possible, as well as the development of bradycardia.

In addition, the effect of Ambene provides activation of liver enzymes, so their content in venous blood increases dramatically. Cases of allergic reaction and eczema after application of the drug are not uncommon.

Overdose

Use of the drug in large doses ensures the appearance of unpleasant symptoms in the form of nausea, vomiting, dizziness, fever, pulmonary edema, anemia, heart failure, respiratory depression and even coma. Therefore, observe the precautions when using the drug and follow the instructions clearly.

Interaction with other drugs

If you want to reduce pressure, then the combination of Ambene with drugs designed to reduce pressure, will not bring a bright effect. "Ambene" has a disastrous effect on the effect of certain medications, for example,"Sulfinpyrazona."

It is not recommended to apply Ambene in conjunction with"Metatrescate", since you will only increase the toxic effect on your body.

The effect of the drug Ambene in the power to weaken the drug calledRifampicin. Anabolic steroids act differently.

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Be wary of combining drugs that have a persistent anti-inflammatory effect, since thiscan cause irreparable harm to health.Refuse and from the use of alcoholic beverages during the treatment of "Ambien".

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Consult an experienced doctor, before you start taking Ambene in combination with other medications.

special instructions

The substance phenylbutazone in the drug has the ability to exerta strong effect on thyroid function, therefore, the analysis for the study of this body, which you have planned, will have to be postponed for a certain period. Namely, analyzes can be carried out not earlier than through2 weeksafter the end of the course of treatment.

Note! The component of cyanocobalamin in the drug can actually distort the results of laboratory studies in patients with funicular myelosis, as well as pernicious anemia.

Be attentive to the medicine "Ambien", if you suffer from tuberculosis, mental disorders, acute lung diseases, epilepsy, and diabetes mellitus.

At the beginning of treatmentthe patient is prescribed a minimal dose of the drug.

This is especially applicable to patients of senile age and patients with weakened immunity.

To avoid redness, irritation in the area where the injection was administered, insert the needle deeply, but very slowly and carefully. The above manipulations must be carried out in accordance with all the rules.

During the treatment with the drug Ambeneenrich your diet with products that are sources of beams, potassium, fiber and vitamins.

To maintain health, it is important that all these trace elements enter the body.

At the same time, minimize the intake of fat, carbohydrates, and also table salt.

Reviews

Opinions about the drug "Ambene" vary, on the Internet you can find reviews both in a supportive and in a negative way.

Vladimir, 38 years old, Moscow:"For a long time I suffer from osteochondrosis, unbearable pains in the back tortured me, it reached up to the fact that I did not want to live.

Until I came across the drug Ambien! I decided to prick it strictly according to the doctor's recommendations.

And you know,the result of me simply shocked, of course, in a positive way!I know that this is a product of excellent quality. "

Vitaliy, 50 years old, Ekaterinburg:"When I went to the pharmacy, on the shelf of the store window in the drugstore, I immediately saw the unique drug Ambene. It turns out that it is intended for the treatment of the spine, which I needed.

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But that's the trouble - the medicine is absolutely not worth the money! It must be treated properly, and not only to remove pain.

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It would be advisable to use analogues of this medicine, so thatI do not advise, except that I recommend those people who do not peck at the money".

Analogues

If, in view of the individual characteristics, "Ambien" does not suit you, then the doctor can prescribe you an analogue of this medicine.

The drug most similar in effect to Ambien iscombination of Dexamethasone with Milgamma.

Very successful recognizedThe combination of Neurobion with the same Milgamma.

A source: http://SpinaSpina.com/lechenie/preparaty/ukoly-ambene-instrukciya.html