Omaron

Omarone refers to a combination of drugs that can improve blood circulation and metabolic processes in the brain tissues.

It carries a nootropic, antihypoxic and vasodilating effect - the vessels of the brain expand especially well.

Interneuronal transmission in the central nervous system also improves, cell resistance to hypoxia increases, protein and energy exchange, and a number of other effects achieved with the joint action of the two active substances of the drug.

Clinical and pharmacological group

A drug that improves cerebral circulation and brain metabolism.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Omaron in pharmacies? The average price is at the level of130 rubles.

Form of issue and composition

The preparation is produced traditionally in the form factor of flat-cylindrical tablets with a risk, the color is white, light marble is permissible.

Basic substances:

Piracetam;
Cinnarizine.

Also contains a number of excipients:

lactose monohydrate;

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colloidal silicon dioxide;
calcium stearate monohydrate;
crospovidone;
povidone K30;
magnesium hydroxycarbonate hydrohydrate.

The drug is packaged in 10-pack squares, in one typical cardboard pack, there may be 3, 6 or 9 such cells.

Pharmacological effect

Omarone - a combined drug that has antihypoxic, nootropic, vasodilating action. Piracetam, due to the acceleration of energy and protein metabolism, improves the metabolic processes in the brain cells. It accelerates the processing of glucose by neurons and increases their resistance to hypoxia, is able to improve regional blood circulation in the ischemic zone.

Piracetam activates metabolic processes in the brain by increasing energy and protein metabolism, accelerating the utilization of glucose by cells and increasing their resistance to hypoxia. It improves interneuronal transmission in the central nervous system, improves regional blood flow in the ischemic zone.
Cinnarizine is a selective blocker of slow calcium channels, which inhibits the entry of calcium ions into cells and reduces them the content in the depot of the plasmolemma, reduces the tone of the smooth muscles of the arterioles and their response to biogenic vasoconstrictors. Has a vasodilating property, without having a significant effect on blood pressure. It shows moderate antihistamine activity, reduces the excitability of the vestibular apparatus and the tone of the sympathetic nervous system. Increases the elasticity of erythrocyte membranes, their ability to deform, reduces the viscosity of the blood.

When taken orally, the tablets are completely absorbed in the gastrointestinal tract. The maximum concentration of the substance in the blood is reached in 3-5 hours, and in the cerebrospinal fluid - about 2-7 hours. Medicinal substances pass well BBB, spreading across all tissues of the body. The brain accumulates in the occipital, parietal, frontal lobes and the cerebellum. Pyracetam is not metabolized in the body, and 95% of the substance is excreted in the urine after 26-30 hours. Cinnarizine binds 90% to blood proteins, its metabolites are completely eliminated after 4 hours by kidneys and intestines.

Indications for use

What helps? Omarone is prescribed concurrently with other drugs in the treatment of diseases of the central nervous system, accompanied by a decrease in intellectual-mnestic functions:

Depression;
Ménière's syndrome;
Vestibular disorders;
Migraine (for prevention);
Kinetosis in adults and children (for prevention);
Encephalopathy post-traumatic or post-toxication;
Psycho-organic syndrome with predominance of adynamia and asthenia;
Lack of intellectual development in children;
Insufficiency of cerebral circulation (recovery after hemorrhagic and ischemic stroke, atherosclerosis of cerebral vessels).

Contraindications

Absolute:

Lactase insufficiency, lactose intolerance, glucose-galactose malabsorption syndrome;
The period of pregnancy and breastfeeding;
Children under five;
Psychomotor agitation;
Parkinsonism (including Parkinson's disease);
Hemorrhagic stroke;
Severe renal and / or hepatic insufficiency;
Huntington's disease;
Hypersensitivity to any of the components of the drug.

Relative (take with care):

Extensive surgical interventions;
Increased intraocular pressure;
Severe atherosclerosis of cerebral vessels;
Chronic renal failure;
Diseases of the kidney and / or liver;
Violation of hemostasis;
Severe bleeding;
Porphyria;
Epilepsy;
Hyperthyroidism;
Propensity to neurotic reactions.

Dosage and route of administration

The instructions for use indicate that Omaron tablets are administered orally, during or after a meal.

Adults - 1-2 tablespoons. 3 times / day for 1-3 months, depending on the severity of the disease. It is possible to conduct repeated courses of treatment - 2-3 times a year.
Children over 5 years - 1-2 tables. 1-2 times / day. Do not use for more than 3 months.

For the prevention of kinetosis: adults - 1 tab., Children over 5 years - 1/2 tab. 30 minutes before the start of travel, with repeated admission (if necessary) every 6-8 hours.

In chronic renal failure (creatinine clearance 20-80 ml / min) - 1 tab. 2 times / day.

Side effects

Omarone can cause unwanted reactions from various systems of organs. The instruction to the preparation warns about the following possible side effects:

Musculoskeletal: rigidity of muscles.
Skin: dermatitis, itching, rashes, keratosis, hyperhidrosis.
Immune system: hypersensitivity and exacerbation of allergic reactions.
Mental reactions: depression, anxiety, hallucinations, increased excitability.
Digestive: dry mouth, dyspepsia, nausea, abdominal pain. Diarrhea, cholestatic jaundice.

A prolonged course of treatment can lead to an increase in body weight. Also, some patients experienced increased sweating, increased blood pressure, thrombophlebitis, increased sexual arousal.

Overdose

Overdose causes the component of the drug - cinnarizine because of its anticholinergic activity. Symptoms are as follows: impaired consciousness, vomiting, decreased blood pressure, diarrhea with blood, and spastic pain in the epigastric region.

Treatment: gastric lavage, intake of enterosorbents (activated charcoal, Polysorb, Smecta, Enterosgel), symptomatic therapy according to indications.

special instructions

Before you start using the drug, read the special instructions:

It is not recommended to drink alcohol during treatment.
In the period of treatment in patients with arterial hypotension, a more significant decrease in blood pressure is possible.
With prolonged use, it is recommended to monitor liver and kidney function (especially in patients with chronic renal failure).
Distortion of the results of the doping test and allergic skin tests is possible; 4 days before the test, the drug should be withdrawn.

Drug Interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

May intensify the effect of oral anticoagulants.
Vasodilating agents enhance the effect of the drug.
Improves tolerability of antipsychotic drugs and tricyclic antidepressants.
With the simultaneous use of piracetam enhances the central effects of thyroid hormones (possible tremor, anxiety, irritability, sleep disturbances).
With simultaneous use, it is possible to strengthen the sedative effect of drugs that depress the central nervous system, as well as ethanol, nootropic and antihypertensive agents.

Reviews

We picked up some reviews of people who used the drug Omaron:

Lyudmila. The microinsult was transferred, there were awful headaches, noise in ears, etc. Has made a tomography: a microinsult. 2 years saw Betaserc and analogues, Vinpocetine, Sermion, and others. 3 times a day. 5 years I drink Omaron and Sermion in turn after 3 months, once a day. and Betaserc also once a day. Now I'm not complaining about my health. I complain only about old age, but I try to hold on. I am 75 years old. All of health!
Pauline. In the complex treatment of my daughter (vestibular disorders), Omaron was prescribed along with other drugs. I would like to note that we did not notice any special improvements in the use of this medication, but headaches, which were already exhausted from time to time - on the contrary, they intensified and we had to replace the drug. Of course, I do not exclude that it was personal immunity to the drug, but we do not use it anymore ..
Paul. According to the description, the drug is very good. Only here is one question - Omaron comes as a remedy for a depressive state (including), and in "side effects" it is indicated that most often when taking the drug there is depression. All the same, any drugs should be taken on the advice of a doctor and under his supervision and not engage in self-medication, otherwise you can be cured to the incurable.

Doctors do not recommend using Omaron, whose reviews indicate positive dynamics during treatment, more than 3 months. Some patients note the resumption of symptoms with the cancellation of Omaron. To date, Omaron is one of the most effective and harmless drugs for normalizing cerebral circulation and improving memory.

Analogues

Structural analogs for the active substance:

Combbitropyl;
NooCam;
Piracesine;
Fezam.

Also Omaron's aalogues are represented by a rather extensive list of drugs with a similar effect, the most famous of which are:

Avia Sea;
Aviomarine;
Aminalon;
Anvifen;
Validol;
Vertigohel;
Vinpotropil;
Dramina;
Kinedryl;
Kokkulin;
Combbitropyl;
Noophen;
Pipolphen;
Pyrroxane;
Ciel;
Torekan;
Fezam;
Fenibut;
Cinnarizine.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 ° C. Shelf life of the drug is 3 years. At the end of this period, the use of the medicinal product is prohibited.