Rince

width = Rinsa is a combined medicine, antipyretic, antihistamine, analgesic, anticongestive, psychostimulating action, for relief of symptoms of acute respiratory-viral infection.

The use of Rince must begin with the first signs of a cold and other infectious diseases (influenza, ARVI), which are caused by fever, acute rhinitis and headaches.

With a cold, the drug quickly improves well-being.

Clinical and pharmacological group

The drug for symptomatic therapy of acute respiratory diseases.

Terms of sale from pharmacies

You can buy without a doctor's prescription.

Price

How much does Rince cost in pharmacies? The average price is at the level of165 rubles.

Composition and form of release

Pharmaceutical form of Rinza - tablets: flat, round, pink, with white and dark pink patches, with bevelled edges and separation risk on one side (10 pcs. Each). in aluminum / PVC blister or aluminum / aluminum blister, in a cardboard bundle of 1 or 2 blisters).

Composition of 1 tablet:

Active components: caffeine - 30 mg, paracetamol - 500 mg, phenylephrine hydrochloride - 10 mg, chlorphenamine maleate - 2 mg;
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Additional substances: sodium carboxymethyl starch (type A), talc, magnesium stearate, sodium methylpahydroxybenzoate, povidone (K30), corn starch, silicon dioxide colloid, dye Crimson (Ponso 4R).

pharmachologic effect

Rinsa is a combined preparation. Among the ingredients are four main components, each of which has its own therapeutic effect.

Paracetamol suppresses the synthesis of cyclooxygenase and affects the hypothalamic centers of thermoregulation and pain, which is responsible for its analgesic and antipyretic properties.
Phenylephrine - refers to alpha-adrenomimetics, it has a vasoconstrictive effect, due to which reduces edema of the mucous membrane of the nasal cavity, appendages of the sinuses, upper respiratory tract and manifestation coryza.
Chlorphenamine belongs to the blockers of histamine H1 receptors and is characterized by an antiallergic effect, expressed in the elimination of exudative manifestations, reduction of puffiness and hyperemia of the mucous membranes of the upper respiratory tract and paranasal sinuses, a decrease in the severity of itching of the throat, nose and eye.
Caffeine is a psychostimulator that helps to overcome general weakness and drowsiness. It somewhat strengthens the effect of the remaining components.

Information about the pharmacokinetic profile of Rince is not available at the moment. However, it is known that paracetamol is absorbed rather quickly from the middle parts of the gastrointestinal tract and intensively binds to plasma proteins. Its maximum concentration in the blood plasma is reached about 1 hour after admission. Paracetamol also penetrates the blood-brain and placental barriers.

Indications for use

Doctors often prescribe Rinza - instructions for the use of the drug contains indications for use:

symptomatic treatment of colds;
therapy of acute viral respiratory infections, influenza, acute respiratory infections;
treatment of diseases accompanied by fever, rhinorrhea, pain syndromes, sinusitis, pharyngitis (the drug lowers the temperature).

Contraindications

Absolute contraindication to the beginning of this drug is individual hypersensitivity to one or more active components or excipients.

Pathologies in which the drug is not prescribed:

atherosclerosis of the heart arteries;
hypertonic disease;
erosive and ulcerative lesions of the digestive tract (in the phase of exacerbation);
bleeding in the gastrointestinal tract;
"Aspirin triad" (intolerance to salicylates, etc.) NSAIDs in combination with bronchial asthma and polyposis of the nose or paranasal sinuses);
severe functional kidney failure;
hepatic insufficiency (incl. on the background of alcoholism);
hepatitis and others. active liver disease;
diabetes.

Rinza is contraindicated in children and adolescents under 15 years of age.

Intended use for pregnancy and lactation

Pregnancy and lactation are contraindications for taking Rince.

Dosage and route of administration

As indicated in the instructions for use, Rince tablets are taken orally.

Single dose - 1 tablet. The recommended frequency of taking the drug is 3-4 times a day (maximum - 4 tablets a day).

The duration of the treatment course is up to 5 days.

Side effect

Taking Rince tablets can lead to the development of unwanted reactions from various organs and systems, which include:

The system of breathing - spasm of smooth muscles of the walls of the bronchi with their constriction (bronchospasm).
Nervous system - sleep disturbance (poor falling asleep), increased excitability, dizziness.
Cardiovascular system - increased heartbeats (tachycardia), increased blood pressure.
Body of vision - increased level of intraocular pressure, paresis of accommodation, mydriasis (dilated pupils).
The urinary system is the development of renal colic, inflammation of the kidney tissue (interstitial nephritis).
Blood and red bone marrow - a decrease in the number of platelets (thrombocytopenia), granulocytes (granulocytopenia) per unit volume of blood, anemia (anemia).
Digestive system - dryness in the oral cavity, nausea, periodic vomiting, pain in the stomach (upper abdomen), toxic effects on the liver.
Allergic reactions - rash, skin itching, reaction in the form of nettle burn (urticaria), swelling of tissues with preferential localization in the face and external genital area (angioedema Quincke).

The development of negative reactions is the basis for stopping the use of Rince tablets and going to the doctor.

Overdose

When an overdose of the drug may appear such symptoms as pallor of the skin, anorexia, nausea, vomiting, hepatonecrosis, increased activity of hepatic transaminases, an increase in prothrombin time.

In this case, it is recommended to wash the stomach and the appointment of activated charcoal, symptomatic therapy, the introduction of methionine after 8-9 hours after an overdose and acetylcysteine after 12 hours.

special instructions

Do not take concomitantly with other drugs containing paracetamol.

During the period of application of the Rinz preparation, one should refrain from drinking alcohol, sleeping pills and anxiolytic drugs (tranquilizers).

The patient should be informed that if the drug has become unusable or has expired, then do not throw it into sewage or into the street. It is necessary to place the drug in a bag and put it in a garbage container. These measures will help protect the environment.

Interaction with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

Furazolidone, MAO inhibitors - possibly the development of hyperpyrexia, excitation, hypertensive crisis under the influence of chlorphenamine;
Tricyclic antidepressants - the adrenomimetic effect of phenylephrine increases;
Halothane - the threat of ventricular arrhythmia increases;
Guanethidine - reduces its hypotensive effect under the influence of phenylephrine, and simultaneously increases the alpha-adrenostimulating activity of the latter;
Sedatives, MAO inhibitors, ethanol - their effectiveness is enhanced;
Phenothiazine derivatives, antiparkinsonian and antipsychotic agents, antidepressants - the threat of constipation, dry mouth, urinary retention is aggravated;
Glucocorticosteroids - the risk of glaucoma increases;
Diuretic drugs - their effectiveness decreases under the action of paracetamol;
Ethanol - increases the sedative effect of antihistamines;
Barbiturates, carbamazepine, diphenin, rifampicin and other inducers of microsomal liver enzymes - the threat of hepatotoxic action of paracetamol is aggravated.

Reviews

We offer you to get acquainted with the opinions of people who used the drug Rince:

Anna. Rinza is my salvation from the common cold! this is the only thing that helps, even better than drops from the common cold, since there is Phenyloaffrine. And the price at it is qualitatively lower than offered in drugstores of newfangled preparations. Highly recommend!
Elena. My husband is unwell, I wanted to take a rifle, but the doctor did not advise me very much. He says that there is phenylephrine, and he harms the heart, makes him straight for wear and tear. So I bought my husband Antigrippin, which produces natural products, and the composition is understandable, is not harmful to the heart. The husband drinks these tablets effervescent and is easy for him, Monday he has already gathered for work, then a couple of days ago he almost prepared to die, so a good medicine.
Timothy. At work I got infected from a colleague of ARVI, I felt the temperature in the morning, my muscles began to break. I realized that these are signs of an approaching flu and began to act. I bought Rince's pills in the pharmacy, drank them on instructions for five days, and the disease receded, never having begun. I will keep the drug at hand, because the season of epidemics is just beginning.

Analogues

There are direct and indirect analogues of Rinza, which coincide with the original drug in its active composition or similar action on the body for colds and respiratory diseases. Popular substitutes for the drug are tablets:

Rinicold;
Flute;
Agicold;
Gripout;
Milistan;
Nolgripp;
Coldcourt;
Coldrin;
Lorkold;
Radicold;
Gripflex.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The shelf life of Rince tablets is 3 years. The preparation is important to store in the original factory packaging, dry, protected from light and inaccessible to children at an air temperature of no more than + 25 ° C.