Anuran Ears Drop: Instructions for Use

Anauran are ear drops, shown to patients with external (chronic and acute forms) and average (in the preperforative stage, when the tympanic membrane under pressure of the liquid did not burst) otitis.

Also, the drug is an excellent local remedy for the treatment of exudative otitis media found in a patient in chronic form, and when there are various purulent complications after the intervention in the ENT surgeon.

On this page you will find all information about Anuran: the full instruction on the application to this medication, the average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used ear drops Anauran. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug with antimicrobial and local anesthetic action for topical application in ENT practice.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Anauran cost? The average price in pharmacies is at the level of360 rubles.

Form of issue and composition

The drug is released in the form of drops of the ear: a clear clear liquid without a smell (in bottles of dark glass of 25 ml with a lid-dropper, 1 bottle in a carton).

1 ml of drops contains the components:

• active: polymyxin In sulphate - 10 thousand. ME, neomycin - 5 mg (which corresponds to 3.75 thousand. ME), lidocaine hydrochloride - 40 mg;
• auxiliary: purified water, glycerol, propylene glycol, benzalkonium hydrochloride.

Pharmacological effect

The drug has antibacterial and analgesic effects. Neomycin has a disastrous effect on most types of pathogenic microorganisms, but it has an insignificant effect on Streptococcus spp.

Polymyxin has a powerful bactericidal effect, but it has no activity on fungi and Gram-positive cocci. It performs a local-irritant function. Lidocaine quickly eliminates pain and itching.

Pharmacokinetic studies of the drug were not conducted. This is due to the fact that it is intended solely for local use. The appearance of systemic effects is unlikely.

Indications for use

The main active components of the remedy are broad-spectrum antibiotics. Therefore, the drops produced under the name Anauran are effectively used against virtually all types of infections with bacterial etiology.

Instructions for use indicate the following diseases:

• complication in the form of suppuration after anthropoidectomy or anthropoidoidotomy;
• tympanoplasty - sanation of the middle ear and restoration of the position of the bones in this area;
• inflammation of the auricle of a chronic or acute type;
• infectious otitis media (the drum cavity is inflamed, that is, the middle ear).

Anauran ear drops are for topical use only.

Contraindications

As such effects, which can cause problems in the patient, ear drops with antibiotic "Anauran" do not have. The patient should not have any allergies to all of the components of the drug declared by the manufacturer. However, the manufacturer warns that:

1. Children under 1 year old, pregnant women and lactating mothers should take the medicine only under supervision the doctor in case of acute necessity (when the benefit for the patient exceeds the possible risks);
2. predisposed to ear allergic reactions (itching, exfoliation of the outer ear tissue, hyperemia) should also be taken with caution.

Also, the manufacturer warns that "Anauran" can not be taken longer than 7 days, as long-term use of the medicine can lead to the above allergies.

Application in pregnancy and lactation

Pregnant and lactating women should apply Anauran only in special cases and exclusively under the supervision of a doctor.

Instructions for use Anauran

The instructions for use indicate that Anauran is for topical use. Drops should be added to the external ear canal, using a special pipette. It is recommended to keep the head inclined for some time after applying drops. The duration of the course of therapy and the dose of the drug Anuran is determined by the doctor, given the nature and severity of the disease, and concomitant therapy (in case of severe infections, additional prescription of systemic antimicrobial agents is recommended).

• Adults, as a rule, are recommended to apply 4-5 drops from two to four times a day.
• Children, as a rule, are recommended to apply 2-3 drops three times or four times a day.

The recommended duration of treatment is from 3 to 7 days. Do not use the drug Anauran for more than 7 days in a row (except when the doctor advises otherwise).

Side effects

The most common are allergic reactions that quickly disappear after discontinuation of the drug and do not require treatment: itching, flaky skin, redness.

The drug is very poorly absorbed into the total blood flow with topical application and contains a small dose of medicinal substances, as a result of which systemic effects are absent in most cases.

However, with prolonged admission, nephro- and ototoxicity may manifest due to the Neomycin that is part of the drug.

Overdose

Information about the overdose is not known at this time.

special instructions

1. Use of the drug is allowed only with ear diseases. Persistent infections require an additional intake of antibacterial agents.
2. If the need to prescribe the drug to pregnant women is mandatory, the doctor's control. Such patients can be prescribed drops only if the benefit of taking it significantly exceeds the existing risks. Women who are breastfeeding should use Anauran after a medical consultation.
3. Admission to children under one year is strictly under constant medical supervision and only when absolutely necessary.
4. A long course can provoke the emergence of resistance of microorganisms to the components of the drug Anauran.

Drug Interactions

Do not use the drug together with antibiotics of the aminoglycoside group (Streptomycin, Gentamycin, Monomycin, Kanamycin, Amycomycin). This can lead to increased ototoxic effect.

Reviews

Many patients are satisfied with the drug, since the desired therapeutic effect is created with the classical dosage indicated in the instructions. It is noted that the remedy is well tolerated by children, it relieves painful symptoms.

Negative reviews are rare, often associated with the side effects that arise from a violation of the admission scheme. Some patients with hypersensitivity on the third day or later have an itch, which is the result of fungal attack.

But the likelihood of developing candidiasis is higher if antibiotic suspensions or tablets are used simultaneously with topical administration of drops.

Analogues

Analogues of ear drops "Anauran" in domestic medicine are absent - none of the manufacturers produces drugs with similar composition. In cases where it is impossible to adopt this drug, you can pay attention to:

• "Otipaks";
• "Otinum."

In addition, the patient can always receive the active substances that make up the "Anauran", in its pure form - polymyxin B with neomycin and lidocaine. Also, one should not forget that a similar medication should be approved by an otorhinolaryngologist, since "Anauran" is incompatible with certain preparations of the otorhinolaryngological spectrum.

Storage conditions and shelf life

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