How to take Pirantel tablets from worms: instructions for use

Pirantel is an anthelmintic medication used for diseases caused by various intestinal parasites (ascariasis, enterobiasis, ankylostomiasis, etc.).

It causes neuromuscular blockade in sensitive helminths, which facilitates their removal from the digestive tract without stimulation and stimulation of migration of affected worms. It acts on parasites in the early phase of development and on their mature forms, does not affect the larvae during their migration in tissues.

The drug can be used not only in adults, but also in children from 6 months, which makes it quite convenient for treating common helminthiases. But its use is fraught with a certain risk, therefore it should be remembered that it is necessary to give the children to Pirangel only according to the doctor's order and strictly following the instructions.

Clinical and pharmacological group

Anthelmintic preparation.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much are Piarantel tablets in pharmacies? The average price is at the level of30 rubles.

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Form of issue and composition

The following dosage forms of Pirantel are available:

Suspension for oral administration: homogeneous, yellow (15 ml in bottles of dark glass, with a measuring cap in the kit, 1 set in a pack of cardboard).
Tablets: biconvex, yellow, oval, with a risk on one side (3 pcs. in blisters or strips of aluminum foil; 1 blister or strip in a pack of cardboard).

The 5 ml suspension consists of:

Active substance: pyrantel pamoate - 0.735 g (corresponds to the content of pyrantel - 0.25 g).
Auxiliary components: purified water, chocolate flavor S 2761 and flavoring "ice cream" (artificial and natural aromatic substances, natural, dye caramel, water, propylene glycol), polysorbate 80, sorbitol 70% solution, propylparaben, methylparaben, xanthan gum, sucrose, sorbic acid.

The composition of 1 tablet includes:

Active substance: pyrantel pamoate - 0.72 g (corresponds to the content of pyrantel - 0.25 g).
Auxiliary components: talcum purified, sodium carboxymethyl starch, magnesium stearate, corn starch, gelatin.

Pharmacological effect

Pyrantel is an anthelminthic agent that acts on nematodes (class of round worms-parasites). The drug has an effect on both helminths, which are in the early stage of development, and on their mature forms. Pirantel is unable to act on the larvae of parasites migrating in tissues.

The drug is effective against such types of parasites as ascariasis (Ascaris lumbricoides), pinworms (Enterobius vermicularis), pathogens trichocephalosis (Trichostrongylus orientalis and Trichostrongylus colubriformis) and hookworm (Ancylostoma doudenale, Necator americanus).

The mechanism of action of the drug is based on its ability to cause neuromuscular blockade in sensitive parasites, which makes it easier to remove them from the digestive tract. The use of pyrantel does not stimulate the migration of diseased helminths.

Indications for use

If the study of feces showed the presence of helminths in the body, roundworms, hookworms - this will serve as an indication for the appointment of Pirantel. According to the instructions to take the medicine is necessary when stating such diagnoses as:

Ascaridosis - infection with ascarids;
trichocephalus - lesion of the gastrointestinal tract by nematodes;
ankylostomiasis - infection with worms, leading to anemia;
neckaroz - helminthiasis caused by the multiplication of parasitic roundworms;
enterobiosis - when infected with pinworms.

Use Pirantel not only for the treatment of helminthiosis, but also for the prevention of parasitic diseases. Then in a single dose to take medicine is necessary not only for the sick person, but also for his family members. Preferred forms: tablets - for adults, suspension for a child. In addition, it is desirable to sanitize the premises, give tablets from worms to pets. For testing after 2-3 days, it is necessary to take tests of feces.

Contraindications

Absolute for tablets:

myasthenia gravis (period of therapy);
age is less than 3 years;
individual intolerance of the components contained in the preparation.

Relative (diseases / conditions, in which case the appointment of Pirantel requires caution):

liver failure;
pregnancy;
the period of breastfeeding.

Absolute for suspension:

liver failure;
myasthenia gravis;
age younger than 6 months;
combined therapy with levamisole and piperazine;
rare congenital intolerance to fructose;
lactation period;
individual intolerance of the components contained in the preparation.

Relative (diseases / conditions, in which case the appointment of Pirantel requires caution):

anemia;
exhaustion of the body;
age from 6 months to 6 years and weight less than 10 kg;
pregnancy.

Use in pregnancy and lactation

In pregnancy, you can use this medicine solely on strict indications, carefully comparing the benefits for the future mother and harm to the fetus. During breast feeding the drug is not used.

Dosage and route of administration

The instructions for use indicate that Pirantel tablets are thoroughly chewed and taken orally, during or after a meal, washed down with water (1 cup).

Recommended doses:

children aged 3 to 6 years: 1 piece;
children aged 6 to 12 years: 2 pcs .;
children aged 12 years and adults weighing less than 75 kg: 3 pcs .;
adults weighing more than 75 kg: 4 pcs.

To avoid self-invasion, a second course of therapy is allowed after 21 days after the first.

In cases of isolated ascariasis take 5 mg of funds per 1 kg of weight (once), ascaridosis and enterobiosis, and mixed infestations with these parasites - a dose intended for the course based on a calculation of 10 mg per 1 kg of weight (once).

In the treatment of ankylostomidosis, a combination of non-carotenosis with ascariasis or other combined helminthic lesions take 10 mg per kg of body weight per day for 3 days, with the treatment of massive infestations of Necator americanus - 20 mg per 1 kg of body weight per day for 2 days.

Pirentel suspension - instructions for use

Suspension for children is used according to the indications, before shaking it should be shaken.

Patients with ascariasis and enterobiasis are prescribed an average dose of 10-12 mg per 1 kg of weight in one dose. Children after 6 months should receive syrup in a dose of 2.5 ml per 10 kg of weight in one session. Adult patients (up to 75 kg) receive 15 ml per 1 reception. If a person weighs more than 75 kg, one drink should drink 20 ml of the drug. To improve the effectiveness in the treatment of enterobiosis, you should carefully follow all the rules of personal hygiene. It is recommended to have another course of therapy three weeks later.

Patients with ankylostomiasis in endemic areas or in case of severe invasion the drug is prescribed, based on a dosage of 20 mg per 1 kg of weight for 2 or 3 doses, treatment lasts 2-3 days. Dosage per day is calculated as follows:

children after 6 months receive 5 ml of syrup per 10 kg of weight;
with a weight of 75 kg - 30 ml of syrup per day;
with a weight of 75 kg - 40 ml of syrup per day.

Under the condition of mild invasion of Ankylostoma duodenale, it is sometimes sufficient to take a single dose of 10 mg per 1 kg.

Side effects

Against the background of taking the drug, the development of pain and stomach cramps, diarrhea, vomiting, nausea, lack of appetite. In rare cases, there is a transient increase in the concentration of aspartate aminotransferase in the blood serum, fever, rash, weakness, insomnia / drowsiness, dizziness, headache.

In isolated cases, paresthesia, hallucinations with confusion, hearing impairment were recorded.

Overdose

When ingesting a large number of tablets or independently exceeding the dose recommended by the doctor, the patient develops signs overdose, which are expressed by the intensification of the above-described side effects and severe disorders of the nervous system.

Treatment of an overdose consists in the immediate washing of the stomach and the introduction of enterosorbents. If necessary, symptomatic therapy is performed. Antidote preparation is not present.

special instructions

After taking Pirantel laxatives are not prescribed. In the treatment of enterobiasis, all co-residents must be treated simultaneously. Careful hygiene (cleaning the living quarters and cleaning clothes to destroy helminth eggs) serves as a preventive measure against reinfection. 14 days after treatment with Pirantel, parasitological control tests should be performed.

Considering possible side effects from the nervous system during the use of the drug, care must be taken when engage in potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Drug Interactions

Increases the concentration of theophylline in plasma.

Do not use with piperazine. These funds act antagonistically.

Reviews

We picked up some reviews of people who took pills Pirentel:

Anton. I noticed that my 5-year-old daughter began to eat poorly and complain about pain in the tummy. After receiving the results of the tests, the doctor advised taking Pirantel according to the instructions. Plus, that the medicine is sold as a suspension, so there were no problems with acceptance. The drug did not cause side effects and helped us get rid of the worms.
Jeanne. At me after reception pirantela 3 tablets (74 kg) a week after reception there was a rope-like white something sm 10-12..hotya saw for prophylaxis with the child, ran out of the toilet and still shakes... a little shocked... how it's all disgusting then.
Cyrus. At me the senior daughter after this preparation almost day in reanimation was. And friends, decided to drink the whole family, as a doctor recommended. The whole family and not slazili from the toilet. Crazy vomiting and diarrhea were almost two days. So look yourself.
Anton. An excellent product. We apply it twice a year as a preventive measure, since there are many animals in our house. These are cats and dogs, parakeets and guinea pigs. The medicine is quite inexpensive, well tolerated. In any case, no side effects have occurred either with my wife or children. So you need to protect yourself from parasites, otherwise health problems are guaranteed.

Comments of doctors

Some reviews of parasitologists:

Andrei Pavlovich: Now there is a huge range of anthelmintic drugs. But most of them lead to the death of helminths right in the human body. This leads to intoxication and poor health of the patient. But not in the case of Pirantel. It has an effect on worms and practically does not harm human health. So I really like this drug. Unfortunately, it does not affect all types of parasites. Pirantel is appointed most often. Especially with enterobiasis and ascariasis. Rarely patients complain of adverse reactions. There may be a decrease in appetite and discomfort in the stomach. This is due to the fact that the helminths become immobile. But the drug itself does not cause such reactions.
Nadezhda Dmitrievna: Over the long years of work in parasitology I was convinced for a long time that Pirantel is the safest anthelmintic preparation. It has an excellent mechanism of action: it is not absorbed into the blood, does not affect the functionality of the liver, practically is completely eliminated from the body, after application, after a few hours, it acts on the worms. To understand how to take pyrantel 250 in adult tablets, you need not only read the instructions, but also consult a doctor. Naturally, I do not prescribe this drug during pregnancy. Especially in the first trimester. On the following terms, treatment, perhaps, if there is an urgent need. I really like that for small children the separate form of release made is a suspension. It is convenient to give it to young children over 6 months old. But in this case the dosage should be prescribed only by a doctor.

Analogues

Structural analogs for the active substance:

Helmintox;
Nemocide;
Pirantela pamoat.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Tablets should be kept away from children, in a place protected from light and heat. Shelf life from the date of manufacture of the drug is 3 years, at the end of this period the medicine is disposed of.