From this article you will learn: TromboAss or Cardiomagnum - which is better. Pros and cons of both drugs. In which cases it is better to take the first, and in what - the second.
Contents of the article:
- Composition of preparations
- Side effects and contraindications
- Pros and cons of TromboAC and Cardiomagnet
ThromboAC and Cardiomagnin are prescribed in the same cases. Namely: for primary and secondary prevention of infarction and ischemic stroke, with stable and unstable angina, to prevent thrombosis and thromboembolism after surgical interventions.
Both drugs can be taken only as directed by a doctor. Cardiologist or therapist can prescribe you Cardiomagnum or TromboAss.
Contraindications and side effects of drugs are also identical.
TromboAss and Cardiomagnum have the same active substance - acetylsalicylic acid. This explains the same indications, contraindications and side effects. However, the price of these two medicines varies.
Next, you will learn: what is the difference between these drugs, and which of them is better in what cases.
Composition of preparations
The main active substance is the same - acetylsalicylic acid. Therefore, both drugs have the following effects:
- Antiaggregant( prevent the formation of blood clots).
- Antipyretic.
- Analgesic.
- Anti-inflammatory.
Effects are indicated in descending order, that is, even a small dosage is sufficient to demonstrate antiaggregant effect, but more clinically significant anti-inflammatory action will require more acetylsalicylic acid.
In the amount in which acetylsalicylic acid is present in the preparation TromboACS( there are tablets of 50 and 100 mg), as well as in the Cardiomagnet( 75 or 150 mg), it has only antiaggregant effect, the remaining effects are not pronounced.
There are no other active substances in the TromboASC preparation. But Cardiomagnesium has an additional active substance - magnesium hydroxide. It has a positive effect on the gastrointestinal tract: it lowers the acidity of the stomach and stimulates the intestinal peristalsis. This is a significant plus in the direction of Cardiomagnet, as acetylsalicylic acid increases acidity and irritates the gastric mucosa. Because of this, side effects from the digestive tract are very common: heartburn, nausea, vomiting, stomach pain. The presence of magnesium hydroxide in the composition reduces the risk of these unpleasant symptoms.
However, it costs a cardiomagnet more expensive than TromboAss. As of April 2017, TromboACS costs about 100 rubles per package in pharmacies in Moscow, and Cardiomagnesium costs about 200 rubles( this is an average of both dosages).
The rest of the preparations are completely identical.
Side effects and contraindications
They are the same for both drugs.
Side effects of | Nausea, vomiting, heartburn, pain in the stomach, dizziness, tinnitus, a tendency to bleeding and bruising( most often bleeding gums), allergic reactions. |
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Absolute contraindications | Gastric or intestinal ulcers in the acute phase, exacerbation of gastritis with high acidity, gastrointestinal bleeding, hemorrhagic diathesis, bronchial asthma, pregnancy( 1 and 3 trimesters), breastfeeding, chronic renal or hepatic failure, or heart failure in severedegree, an allergy to acetylsalicylic acid. Also, the drug should be canceled a few days before surgery, even minor, for example, dental. |
Relative contraindications( possible use with caution) | Child age, advanced age, chronic renal or hepatic insufficiency mild, gout, peptic ulcer without exacerbation, chronic gastritis with increased acidity, 2nd trimester of pregnancy, drug allergy to other non-steroidal anti-inflammatory drugsdrugs in the anamnesis. |
However, when taking Cardiomagnesium, there is a lower risk of side effects from the gastrointestinal tract, since magnesium hydroxide reduces the irritating effect of acetylsalicylic acid on the mucous membranes of the stomach and intestines.
If to you the lower price of TromboASS is compared with Cardiomagnum, you can reduce the negative effect of the active substance on the mucous membranes of the gastrointestinal tract yourself. To do this, take the tablet with a lot of alkaline mineral water( you can consult a gastroenterologist for choosing the right mineral water) or milk.
The presence of magnesium hydroxide in the Cardiomagnum has minuses. In case of violations of the kidneys and prolonged use of the drug may develop hypermagnesia - an excess of magnesium in the blood( manifested by the depression of the central nervous system: drowsiness, lethargy, slow heartbeat, impaired coordination).Therefore, patients with renal impairment should be appointed TromboAss, rather than Cardiomagnesium.
Pros and cons of drugs compared to each other
Cardiomagnet | Thromboss |
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Plus Cardiomagnetics - less risk of side effects from the stomach and intestines, since in the composition there is an additional substance - magnesium hydroxide. 1.5 times larger dosage of the main active substance( 150 and 75 mg versus 100 and 50 mg in thromboAC) | The benefits of the TromboAss preparation: the price is slightly lower, caution is possible with mild renal insufficiency. |
Cons: a higher price, it is undesirable to apply for kidney disease. | Minus - in the composition there are no additional substances that neutralize the irritating effect of acetylsalicylic acid on the stomach and intestines. |
When choosing between two TromboAss or Cardiomagnesium medications, it is advisable to stop at:
- Cardiomagnet if you are prone to increased gastric acidity and other gastrointestinal disorders.
- TromboAss if you suffer from kidney disease.
Also, these drugs have a lot of other analogues with the same active substance( Aspirin, Acetylsalicylic acid, Aspirin Cardio, Accecardol, etc.).It is worth paying attention to them also.