Suprax in children with pneumonia

Pneumonia in a child 3 years old - a question for doctors and experienced moms

Answers:

M.P.

the clinical and bacteriological efficacy of cefixime (suprax) has been proven in the treatment of respiratory organs in children. With pneumonia, this drug is not basic, but it can be used. If therapy is already begun then do not interrupt the course. If the temperature is kept for three days, then there will only be an occasion to change the antibiotic.
pneumonia is hard to hear, of course the X-ray is better or call home a clinical blood test done.

Xenia Smyrnova

it is better to go to the hospital, there are procedures done and under supervision, we stayed so three days, and then when it became clear that there was no pneumonia, we left

Natalia Sermyagina

And to you did or made renngen and the analysis of a blood? Watch for the temperature, for a cough (should cough). And in general, the doctor is constantly asking about everything, shake.

Julia Khutornaia

so that there was no stagnation in the lungs, we put the child on a higher pillow and a massage (tapping) of the back, and did not offer an X-ray?

Nataly

an antibiotic for one day will not cure, but the fact that he acted, says that the temperature was normal, It is necessary to drink at least 5-6 days and all is normalized, and cough as the residual phenomena can be within 2 weeks

Natalia

One day it is too early to judge the inefficiency of treatment. The antibiotic is not weak, it is appointed quite adequately. The temperature may still rise, but there must be a downward trend. And the coughing will last a long time, especially in the morning. until the lungs are cleared. Days through 5 children it would be nice to show the doctor (if there is a temperature - then call the doctor again) - listen to the lungs. If the child has attended a kindergarten, do not rush to leave - give the child to stay at home until full recovery.

Irina Zvonkova

be sure to take a picture after the treatment.. we had a sluggish secretive pneumonia flowing for 3 months without temperature... asked to take a picture since there was a cough.. to which the doctors responded no need.. eventually sent to a sanatorium for a month the daughter was 3 years old there was no one found pneumonia... after the institute of pediatrics complications on the heart.. were treated for a long time... health to your baby ...

Big girls do not cry

X-ray the lungs to the child. it seems to me that he has no pneumonia. and the question of the ineffectiveness of the antibiotic is set 72 hours after the start of its administration.

Boris Aizikovich

in general, for the treatment of pneumonia, there is a standard of used drugs from antibiotics to them does not apply the drug Supraks

Irinka

2 Weeks ago, we were discharged (a child of 4 years) from the hospital, everything was almost the same, just did not have time to appoint antibiotic, the fever rose 39.9 - 2 days in a row, did not take a shot of pneumonia, but to the hospital put it. Of course I did not want to go to the hospital, but now I do not regret it. Procedures helped (UHF, inhalation, antibiotic - Amoxiclav). Nedelku home until full recovery (strengthening immunity), and now we go to the garden, but with caution. Nerves are wasted. Health to you and your baby!

Julia Borisovna

I do not see in your question that the child is given an X-ray, on the basis of which it is possible to diagnose and prescribe antibiotics.

Helena

Hello, Nastya! No experienced doctor, even under question such a diagnosis without x-rays and blood tests will not be put!
I bastard, how can I prescribe so many medicines to a child without getting test results!!! !
Coughing can be the result of anything, ARD, bronchitis, yes, up to banal allergies. Nastya, do the tests for the baby!
Did your child's teeth all grow up?

Antibiotic Suprax

Suprax is an antibiotic of the third generation, which contains the active ingredient zymixin.

Supraks - indications for use

This drug is prescribed and used for:

• infectious diseases of the respiratory tract (pneumonia, tracheitis, bronchitis, whooping cough, etc.);
• infectious diseases of the urogenital system;
• for the treatment of inflammatory processes of ENT organs (angina, pharyngitis, otitis, sinusitis, etc.).

The area of ​​application of the suprax is rather wide. This drug belongs to one of the most powerful antibiotics, because of what it is referred to as the so-called stock. Supraks is logical and necessary to use in the case when other, more "sparing" drugs do not have the necessary action. It is undesirable to use the antibiotic suprax to begin treatment of the disease, since in the future the organism may become addicted to this drug.

Suprax in the form of a suspension is the most optimal treatment option for angina and bronchitis in children. If the attending physician prescribes the correct course of treatment with suprax, given all contraindications, allergy indications and drug tolerability. With the optimal dosage and duration of the course, suprax is very well tolerated by children. In hospitals, with the help of this drug, acute forms of pneumonia are treated.

Suprax in otitis media is a very effective drug. It quickly penetrates into the lesions, as its maximum concentration in the blood is reached in four hours. In tissues, this drug is delayed for a long time. Patients are well tolerated with this medication. All these properties suggest that suprax is suitable for the treatment of acute otitis media in children.

Widely used antibiotic supraks with sinusitis, he safely eliminates the pathogens of the disease. In use, this drug is convenient - taking the medicine twice a day and treatment course for three to six days.

Supraks is a release form

The main forms of production of suprax are:

• capsules that contain 200 mg or 400 mg of the active substance;
• granules;
• a suspension which, due to its quick action, as well as a pleasant taste, is used mainly in the treatment of children.

It should be remembered that suprax, like any other drug, is quite individual in its composition, and therefore not suitable for everyone. Many are allergic to an antibiotic. In the treatment with suprax, not all have positive body reactions to this drug. Therefore, about this antibiotic you can hear both positive and negative feedback.

Suprax side effects and contraindications

To this medicine, as well as to some other antibiotic, there are a number of contraindications.

It is forbidden to take suprax to people who are allergic to penicillin and cephalosporin drugs. Caution should be taken supraks to patients with kidney or liver disease. Do not recommend taking it to women during pregnancy and lactation of young children, as well as infants up to 6 months of age.

Side effects of the drug:

• for the digestive tract: dysbacteriosis, jaundice, stomatitis, glossitis, as well as provoking the conditionnausea, vomiting, diarrhea, flatulence;
• for the hematopoietic system: anemia, leukopenia, bleeding;
• for the central nervous system: the appearance of migraine, dizziness, tinnitus;
• for the urogenital system: vaginitis;
• for urinary system: impaired renal function, interstitial nephritis;
• various reactions due to allergy to suprax: manifestation of itching and redness of the skin, itching around the genital area, increasing the number eosinophils in the blood, urticaria, fever, various diseases of the skin and mucous membrane, anaphylactic shock.

In order to avoid diseases associated with the violation of intestinal microflora, as well as microflora of mucous membranes membranes of the mouth, vagina, it is necessary to take probiotics simultaneously with suprax (lacidophil, acipol and etc.).

WomanAdvice.ru

Pneumonia: symptomatology and timing of treatment

When diagnosing pneumonia, the timing of treatment and ways to identify immediately is quite difficult. This topic excites many people who come into contact with such a common, but very dangerous disease. To skip the beginning of effective opposition of an infection means to complicate all process of treatment and even to drive illness in the chronic form fraught with serious complications.

Modern medical products can resist the disease and quickly put on the patient's feet with various types of lesions and the presence of different pathogens. When pneumonia is diagnosed, the timing of treatment depends on numerous factors, both external and those that are determined by the individual characteristics of the body. But in any case it is important that the therapy is timely and lasts until complete cure.

Features of the disease

Pneumonia combines a number of pulmonary diseases characterized by inflammation of the lung tissue, which occurs most often as a result of infection with damage to the alveoli and interstitial tissue. The disease can manifest immediately as an independent process (primary type) or become a complication of another disease (secondary type).

The timing and schedule of treatment are largely determined by the degree and localization of the lesion:

1. Total form: the inflammatory process covers the entire body.
2. Focal variety: defeat is localized as a separate focus.
3. The share form: one pulmonary lobe is damaged.
4. Segmental view: one or more segments of the organ are affected.
5. Unilateral pneumonia: the inflammation covers one lung.
6. Two-sided form: both lungs are affected.

By the nature of the development of the disease, pneumonia is divided into a typical (standard treatment regimens), atypical (individual treatment regimens are required, taking into account the specific causative agent), and a stagnant a type. The most common pathogens are the following viruses: chlamydia, streptococcus, staphylococcus, pneumococcus and mycoplasma.

The severity of the manifestation of the disease is divided into light, medium and severe degrees. The pathogenesis of pneumonia can be acute, prolonged and chronic. The acute form, as a rule, lasts 3-7 days, a protracted type can appear 2-3 weeks, and the chronic form can last for years. In addition, any variety is complicated and uncomplicated.

Symptoms and clinical picture

To determine the treatment regimen, it is necessary to differentiate the type of pneumonia according to the above classifications. Primary diagnosis is carried out according to the characteristic symptoms and clinical picture of the development of the disease. The acute form of the disease manifests itself in specific variants:

1. Croupous pneumonia (lobar): a sudden increase in temperature to 40 ° C, chills, general weakness, pain in the chest, cough (at first dry, then with phlegm).
2. Focal type: the temperature rises gradually, but the signs, although they develop more slowly, are similar.
3. Developed focal pneumonia: begins in the form of acute respiratory viral infections (runny nose, general weakness, perspiration, cough, aches, the temperature rises to 39 ° C) for 3-4 days, then raising the temperature to 40 ° C, increasing cough and malaise.
4. Overgrowth from ARVI: after a cold, which lasts for 7-10 days, pneumonia develops with weakened symptoms.

In general, pneumonia in adults is characterized by the following symptoms:

• very high temperature, coughing (sometimes with traces of blood);
• feverish condition;
• headache;
• abundant sweating, especially at night;
• difficulty breathing and shortness of breath, chills;
• pain in the chest, worse when coughing;
• weakness;
• nausea, until vomiting;
• diarrhea;
• tachycardia of the heart.

At the atypical form of the disease, the manifestation of symptoms is not very obvious and they increase gradually. To treat pneumonia is necessary already at the first manifestations of symptoms.

Treatment of the disease

The therapeutic strategy for pneumonia has several directions:

• strengthening diet, saturated with vitamins and proteins;
• effective antibacterial and antiviral therapy;
• detoxification activities;
• symptomatic therapy.

With mild form of the disease, active therapy with medicinal preparations lasts up to 5 days, and for more severe cases - not less than 10 days.Treatment should last as long as the symptoms appear and the process on the roentgenogram is noticeable. After the elimination of the main signs should continue to take antibiotics within 2-3 days. The end of the course of treatment is determined by the results of complex laboratory and instrumental examinations.

Antibiotic therapy

The main treatment of pneumonia is carried out by the introduction of potent antibiotics, which destroy pathogens. However, to determine the type of pathogen, time is required: bacterial culture, samples, various studies. In some cases, the detection of infection can last for 7-10 days, and delaying the initiation of treatment aggravates the patient's situation.

With this in mind, antibiotics of a wide spectrum of action (Suprax, Ceftriaxone) are prescribed on the first day of the detection of the symptoms of the disease to provide the concentration of the antibacterial component in the blood. When there is a suspicion of an atypical form for adults, a combination of several drugs is used: Suprax with Clarithromycin or Ceftriaxone with Sumamed.

Since the first days of therapy is enhanced by the additional administration of anti-inflammatory drugs, resorptives and vitamin complexes, and they are administered intravenously or intramuscularly.

Immediately as the specific type of agent is determined, targeted antibiotic therapy is applied (usually 3-7 days after the first signs are found). Drugs can be prescribed in addition to the previously accepted course of treatment or in return. The following antibiotics are recommended:

• pneumococcal infection: Benzylpenicillin, Aminopenicillin, Cefotaxime, Macrolide;
• Hemophilus influenzae: Amoxicillin or Aminopenicillin;
• Staphylococcus aureus: Oxacillin, 1st and 2nd generation cephalosporins;
• Chlamydial infections: Macrolides, Tetracyclines, Fluoroquinolone;
• Legionella: Erythromycin, Rifampicin;
• E. coli: Third generation cephalosporins.

Features of treatment of the disease

Even if the selected broad-based antibiotic does not immediately give a positive effect, it should be administered for at least 3 days to create the desired blood content. In some complicated variants, the following therapy is recommended:

1. Pneumonia of the middle stage in people under 60 years of age: Avelox for 5 days in combination with Doxycycline, which is prescribed for 2 weeks.
2. Aggravated disease and for people over 60 years: Avelox in combination with Ceftriaxone for a period of not less than 10 days.
3. Severe form of pneumonia, regardless of the age of the patient: a combination of Levofloxacin with Ceftriaxone, Fortum or Cefepime for a period until the appearance of signs of recovery.
4. With complicated severe form: Sumamed with Tavanik, Fortum with Tavanik, Targotsid with Meronem, Sumamed with Meronem.

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Treatment of congestive form of the disease

Congestive pneumonia is characterized by implicit symptoms and prolonged course. Most often it develops in elderly people and people with a weakened body. Therapy with antibiotics of this type of illness lasts no less than 14 days. The following antibiotics are prescribed: Cefazolin, Cyphran or Penicillin of a protected type. The course of such medication continues for 15-20 days.

If the congestive form proceeds with background heart failure, then an additional intake of glycosides and diuretics is recommended. Complex treatment also includes bronchodilators and expectorants, as well as multivitamins.

In general, with proper treatment of congestive pneumonia, recovery occurs after 20-25 days.

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The duration of treatment of pneumonia depends on a number of factors and severity of the disease. The acute form with proper therapy is cured within 7-10 days. Weakened patients, the elderly and children under 3 years old must be treated in a hospital under the supervision of specialists.

respiratoria.ru

Tzedek

Tzedeks is considered a semisynthetic cephalosporin antibiotic of the third generation, intended for oral use.

The internationally patented term for the drug is Ceftibuten.

This description of the drug Zedex is a simplified and augmented version of the official version of the annotation to the medication. Before making a decision about the use of a medicinal product, it is recommended that consult the doctor and read the manufacturer's annotation that comes with the drug.

The information provided by us is for informational purposes, it should not be used as an instruction for independent treatment.

Remember: only an expert should make a decision about the need to use this or that drug, and also prescribe a dosage and treatment regimen.

Indications for use Cedex

Medicated medication Cedex is used to treat infectious conditions that were caused by bacteria sensitive to the action of the drug.

• Infectious diseases of the upper parts of the respiratory system, in particular, inflammation of the nasal sinuses, nasopharynx, as well as children's and adult scarlet fever.
• Infectious diseases of the lower divisions of the respiratory system: inflammation of the bronchi (acute bronchitis, chronic bronchitis), lungs (pneumonia), in patients who are able to take oral medication.
• Inflammation of the middle ear in pediatrics.
• Infectious diseases of the urinary system, with complications and without them: inflammation of the bladder, urinary ducts, etc.
• Inflammation of the stomach and intestines, provoked by bacteria Salmonella, Escherichia, Shigella, Helicobacter.
• Diarrhea.

Tzedek in angina

Angina (acute form of tonsillitis) requires the appointment of antibiotics, in particular, Tsedeksa, if the disease is caused by microbes, which happens in most cases. Less often, the disease can be caused by a viral and fungal infection: in such cases, the use of antibiotics is impractical.

The most common cause of angina is staphylococcus, or β-hemolytic streptococcus g. A. Bacteria enter the inflamed zone (tonsils) from both the external environment and the bloodstream from other foci of infection in the body.

Cedex in angina may be prescribed only by a doctor, taking into account the identified pathogen and the severity of the disease. The drug should be treated under the supervision of a medical specialist, strictly following the treatment regimen.

Tzedek at otitis

Otitis is an otolaryngological disease that occurs with an inflammatory reaction in the ear. To treat such a disease without the help of antibiotics, which will suppress the development of pathogenic microorganisms in the middle ear, is impossible. Therapy with antibiotics is the basis of treatment of acute purulent otitis media.

Cedex in otitis is most often prescribed when there is no possibility for some reason to determine sensitivity of the bacterial flora to the action of antibiotics, because the preparation of Cedex has a fairly wide spectrum of action. Sometimes, in severe cases, the combined use of several antimicrobial agents is possible, which greatly extends the range of action of drugs.

Tzedek in pneumonia

Pneumonia - an inflammatory disease of the lungs, can be a consequence or complication of the inflammatory process in the bronchi. In the treatment of pneumonia necessarily include antibiotic therapy, since pathogens are usually caused by infectious microbial agents.

Of course, when choosing a drug for the treatment of pneumonia, many factors must be taken into account. This is the presence of contraindications, and the development of "addiction" of microbes to antibiotics, and the speed of getting the drug into the infectious focus. However, one of the defining properties when choosing a drug is the spectrum of antibiotic action.

Tzedek in pneumonia, as a rule, is a preparation of the "first line the first choice. It can be replaced by an alternative drug only when allergic reactions occur.

Often, doctors use a combination of antimicrobial agents to accelerate the healing process and achieve the required level of active substance in the body.

Tzedek for children

Antimicrobial drug Tsedeks often used in pediatrics, more often simultaneously with immunostimulants and vitamin complexes. What makes Tzedek good for children?

The active substance of this drug is ceftibuten - a rather strong antibacterial component, which is often used to treat diseases in which any other antibiotics are powerless. Tsedeks an order of magnitude stronger, for example, penicillin preparations and even some representatives of its own cephalosporin group.

Of course, Tsedeks also has shortcomings: it does not have the action of enterococcal and staphylococcal infection, as well as some other types of microbes.

Nevertheless, this does not prevent active use of the drug in the following childhood diseases:

• angina, scarlet fever, inflammatory processes in the ear and sinuses of the nose;
• acute course of bronchitis and pulmonary inflammation;
• some microbial lesions of the digestive tract, in particular, the small intestine and stomach;
• children's pyelonephritis and cystitis;
• infectious lesion of the osteoarticular apparatus, skin.

Form of issue

Tzedek is produced in the following dosage forms:

• Cedex tablets are capsules for oral administration, white, dense, with a black designation on the surface of the Cedax® capsule. Inside the capsule contains a light powder, possibly with a yellowish or brownish tinge;
• Tzedex powder is a powdery substance for making an oral suspension, with a yellowish tint and a cherry flavor.

Each capsule is represented by: an active component of ceftibutene dihydrate, g, as well as additional constituents (fibers of microcrystalline cellulose, sodium carboxymethyl starch, magnesium stearate). The capsule wall consists of gelatin, sodium lauryl sulfate and titanium dioxide. The designation "Cedax®" on the surface of the capsule is made with a pharmaceutical carcass that consists of pharmaceutical glaze, iron oxide, monoethyleneglycol monoethylate, E 322 additive lecithin, simethicone.

Capsules Cedex consist of two parts, glued together with a special substance, consisting of gelatin and polysorbate.

Powdered substance for the manufacture of suspension: 1 g of substance contains, 44 g of ceftibutene. 1 ml of the finished suspension contains 36 g of active substance.

Suspension Cedex should be a homogeneous consistency, a yellowish light shade, with a pleasant aroma of cherries. The cherry flavor gives the preparation Cedex syrup, obtained from cherries.

Pharmacodynamics

The active substance of the drug, like many other β-lactam antibiotics, has an antimicrobial effect based on the suppression of the formation of the bacterial membrane. Cedex affects a sufficiently large number of bacteria synthesizing β-lactamase, as well as penicillin-resistant microbial cells.

The active substance CEDEX has resistance to plasmid penicillinase and cephalosporinase, except cephalosporinase, synthesized by cytobacteria and enterobacteria, as well as bacteroides, morganella and serrations. Like other β-lactam antibacterial drugs, Cedex is not recommended for use in infectious diseases by bacteria, which have a stability associated with a change in membrane permeability, or with a modification of penicillin-binding proteins.

Cedex is used when the body is affected by the following bacteria:

• Gram (+) bacteria (streptococci, excluding penicillin-resistant strains);
• gram (-) bacteria (hemophilic rod, moraxell, escherichia, klebsiella, indolpositive (including vulgar) proteus, salmonella, shigella, etc.).

There is no evidence of the clinical activity of the drug for streptococcus groups C and G, as well as for some gram (-) bacteria that do not produce a large number of chromosomal cephalosporinases. Tzedex is inactive with respect to most anaerobic bacteria, including bacteroids.

Pharmacokinetics

Through oral administration, Cedex is absorbed more than 90%, leaving the body mostly through the urinary system. The peak level of the active substance in the blood is found 120-180 minutes after a single dose of 400 mg (, g). The limiting plasma concentration may be from 15 to 17 μg / ml. Binding of the active ingredient of the preparation with plasma proteins is from 62 to 64%. The concentration of the main derivative of ceftibutene (active substance) in the blood or urinary excreta can be only 10% of the amount of the active substance.

Biological availability of the drug has a direct dependence on the dosage. The drug taken at a dose of less than or equal to r can be bioavailable at 75-94%.

Stable level of active substance in the blood (with the drug twice a day) is found after the fifth dose.

The half-life of the active substance is about 150 minutes. This period can not vary from the dosage, nor from the frequency of taking the drug.

The effectiveness of the drug does not depend on the time of food intake, however, when using Zedex during or immediately after eating food, its absorption slows down.

The active component easily enters the tissue structures and body fluids. It is found in the liquid medium of the middle ear, in the nasal, tracheal and bronchial secretions.

Ceftibuten is found in the urinary fluid for a day after use, g of the drug. The limiting level in urine is 264 μg / ml: this limit can be detected during the first 240 minutes. About a day after a single use of the drug, its amount in the urinary fluid can be 1, mcg / ml.

Precise information on the content of the drug in cerebrospinal fluid is not available. It is assumed that this amount may not be sufficient for the therapeutic effect.

In elderly patients, a stable concentration of the active ingredient (with Tzedek twice a day) is observed after the fifth dose.

Use of Tzedex during Pregnancy

Specially targeted studies of the use of Cedex during pregnancy have not been conducted. Experiments were made only on animals. As a result of the experiments, the pathological effect of the drug on the course of the pregnancy period, as well as on the development of the fetus and the newborn baby, was not revealed.

But, even considering all of the above, doctors do not advise to appoint Tsedeks to pregnant women safely. Antibiotics are drugs that can harm gradually, and one can never say with certainty about the harmlessness of a given drug. Tzedeks during pregnancy appoint, only well commensurate the possible danger of the drug and its benefits in treatment.

The active substance of the drug is not found in the milk of the nursing mother, but even here experts advise caution. If possible, Zedex should be avoided while breastfeeding.

Contraindications

• Propensity to allergic reactions to antibiotics of the cephalosporin group or to other auxiliary components.
• Children under 6 months of age (no studies have been performed on experimental use of the drug in half-year-old children).
• Children under 10 years can take only suspension of the drug. The encapsulated form presents difficulties for dosing the drug in younger children.
• Hereditary disorders of carbohydrate metabolism, including the failure of fructose, the inability to absorb glucose or galactose, etc.

The drug can be administered with great care, with a tendency to allergic reactions to drugs of the penicillin group, with chronic and acute lesions of the digestive tract, with severe kidney failure, as well as patients being treated hemodialysis.

Side effects of Tzedek

Of the most common side effects of Tzedeks can be identified:

• bouts of nausea;
• stool disorder;
• pain in the head.

More rarely you can observe:

• development of the inflammatory process of the gastric mucosa;
• pain in the epigastric region;
• dizziness, fatigue, drowsiness;
• skin rashes;
• fits of vomiting;
• a disorder of taste sensations;
• rhinitis or sinusitis.

Very rare symptoms may appear:

• accession of infection with clostridia;
• decrease in the number of hemoglobin leukocytes and eosinophils in the blood;
• convulsive conditions.

When you use any of the representatives of antibiotic cephalosporin series, including Cedex, there may be signs allergies (skin rash, itching, breathing disorder, bronchial spasm, anaphylactic shock, Quincke edema, toxic-epidermal phenomena necrolysis). Quite often, and such manifestations as dysbiosis, liquid stool, inflammation of the intestinal mucosa. Prothrombin time and MNO increase in the blood. The kidneys can be affected: the development of toxic nephropathy, renal dysfunction, internal bleeding, and sometimes there is a glucosuria.

Dosing and Administration

How to take Zedex?

The drug is intended only for internal administration. The duration of therapy can be, on average, 5-10 days. Infectious diseases caused by streptococcus pyogenes should be treated with a course of at least 10 days.

The optimal daily dosage of Cedex for adults is, g (encapsulated drug). Reception is conducted regardless of eating.

For the treatment of microbial sinusitis, inflammation in the bronchi and infectious lesions of the urinary system, Cedex is supposed to take a, g / day at a time.

For the treatment of community-acquired pneumonia in patients who are not contraindicated for oral treatment, the optimal dosage should be, g twice a day at regular intervals. The duration of such treatment is from 5 to 10 days, taking into account the presence of complications and the type of disease.

Patients with functional disorders of renal function should take into account that the pharmacokinetic properties of Cedex in the absence of kidneys do not undergo significant changes. For this reason, a change in dosage and treatment regimen may be required only with a lowered creatinine clearance <50 ml per minute. If such clearance is defined as 30-49 ml per minute, then the daily amount of the drug should be reduced to, g. If the clearance is 5-29 ml per minute, then it is recommended to switch to a daily intake, g of the drug.

Sometimes specialists prefer to change the frequency of the drug. For example, Cedex is allowed to use once every two days, with a clearance of 30 to 49 ml per minute, or once every three days with a clearance of 5 to 29 ml per minute.

Patients who undergo hemodialysis procedures up to 3 times per week, the drug is prescribed by, at the end of each procedure.

In childhood, it is preferable to prescribe a suspension of the drug, taking 60-120 minutes before or after eating.

How to take Zedex to children?

Tzedek produced in various dosage forms. However, when treating children, a special, children's version of the drug is used, which is produced and released in powder form. From such a powdery substance, a suspension for oral administration may be further prepared.

Cedex powder, in addition to the active ingredient, is represented by sucrose, xanthan gum, silica, simethicone, titanium dioxide, preservative E 211 and polysorbate, as well as a substance that gives a pleasant suspension cherry flavor.

How to breed Tzedek?

Concerning how to take Zedex to children, it is necessary to highlight the following points:

• in a special measuring container, which is attached to the preparation, pour 25 ml of water;
• ½ of this volume of water is poured into a jar with a powdered preparation and carefully shaken;
• add the remaining volume of water and mix again until uniform.

In pediatrics, the dose of the drug is calculated as 9 mg / kg per day, with the maximum dosage can not be more than 400 mg / day. Most often, the medication is taken once a day, in severe cases, the dose is divided into two doses.

If the child is more than 10 years old, or his body weight is more than 45 kg, then the adult dosage of the drug (, g / day) may be prescribed to him.

In order to determine the dosage of the drug was more convenient, a special spoon-dispenser with risks of 45g, 9g, 35g, and 85g was attached to the powder in the package.

Overdose

Overdose of Cedex does not occur with severe symptoms of intoxication. Studies that were conducted in adult healthy patients suggest that a single dose of the drug at a dosage of 2 g does not give rise to complicated adverse effects. At the same time, all the results of clinical and laboratory tests were in the limit of normal indices.

Antidote to the drug Tsedeks not developed: for this reason, if you suspect an overdose it is recommended to do a gastric lavage, you can also take activated charcoal or another sorbent preparation.

A large amount of the drug can be removed from the body through hemodialysis. Whether peritoneal dialysis will be effective in overdose is not tested.

Interactions with other drugs

Experimental way was established medication of Tzedex and other medications, such as anti-acid agents (aluminum and magnesium compounds) in large dosages, ranitidine hydrochloride, bronchodilator a theophylline. No suspicion of a significant effect of these drugs on each other was found. The effect of Tzedex on the blood content or on the pharmacokinetic properties of theophylline during oral administration has not been determined.

Data on the drug interaction with any other medications was not obtained.

Any antibiotic of the cephalosporin group, including Cedex, may sometimes have an effect on the prothrombin index, leading to its elongation. In particular, this applies to patients who have previously taken oral anticoagulant drugs.

Such patients require constant monitoring of the prothrombin index, vitamin K can be prescribed additionally.

There was no evidence of any influence of Cedex on laboratory and biochemical analyzes.

Storage conditions

The encapsulated form of the drug is stored, as a rule, in places inaccessible to children's antics, with temperature indices ranging from + 2 ° to + 25 ° C.

Powdery substance for use as a suspension should be stored in dry, darkened places, in the temperature range of + 2 ° to + 25 ° C.

special instructions

Price of Tsedex

The price of medication Cedex may differ depending on the price policy of a particular pharmacy network. Price Tsedeksa should be specified from managers and representatives of a pharmacy directly when ordering the drug. Since the prices for medicines can change rapidly for many reasons, then if the price suits you, the drug should be booked in advance.

Average prices for Tzedeks in Ukraine are as follows:

• Tsetde in powder, 36 mg / ml, 30 ml, Schering-Plow - from 12 to 14 $;
• Cedex, capsule form 5 pcs., Schering-Plow - approximately $ 19-20 per package.

Analogues of Tsedex

Often, the pharmaceutical market offers similar medicines, the main part of which is a similar active ingredient, with possibly another dosage form, or with the use of other additional substances.

However, not all drugs have such analogs. This is due, most often, to the inexpediency of their release, or to the impossibility of additional production. Impossibility is due to the regulation of processes in the pharmaceutical market, defined strategy of pharmaceutical companies that produce medicines, as well as some economic reasons.

It is to such a means, which has no analogues, refers to Tzedek. The active ingredient Ceftibuten is not represented in any other known pharmaceutical product.

Of course, if necessary, you can consult a doctor and replace Zedex with another cephalosporin, but this will not be the same, but a completely different drug. Self-replacement of one cephalosporin antibiotic by another is strongly discouraged.

Suprax or Tzedek?

Most often the drug Tsedeks replaced with another representative of β-lactam antibiotic cephalosporins Supraks. This drug is not a direct analogue of Cedex, since it contains in its composition another active ingredient - Cefixime.

However, Suprax is also a representative of the third generation of antibiotics, and is also available as a powdered substance for suspensions and in a capsule form. The drug has a broad antimicrobial effect, but Suprax can not be called a cheap substitute for Cedex: the price for Suprax ranges from $ 35 to $ 55 per package.

If you are faced with the dilemma of what to take, Suprax or Tzedex, contact your doctor: only an expert can determine the appropriateness of a particular drug in your particular case. It is impossible to make an independent replacement: since the preparations are different, sometimes dosage adjustment and the drug administration schedule may be required.

Reviews of Tzedek

If treatment is prescribed by a qualified specialist, then treatment with Tzedex can usually be very effective. When treating many diseases, especially in pediatrics, reviews about Tzedeks are quite positive.

However, it must be remembered that uncontrolled use of antibiotics, and Tzedex is no exception, can lead to very, very unpleasant consequences. Follow the scheme of reception, do not skip the time of drug use, do not understate and do not increase the dosage yourself. The course of Zedex therapy should be completed completely. That is, if you are prescribed a course of treatment for 10 days, and you felt improvement after 5 days, then stop the treatment with the drug in no case it is impossible: the therapeutic course should be brought to an end, otherwise you risk acquiring a chronic course of the disease, or you can buy a number complications.

If you have a long-standing problem with the intestines, then take the drug with caution. At sensations of negative influence of a preparation on intestinal function it is necessary to pay to this attention of your doctor.

Do not forget that during the period of Zedex therapy, however, as with any other antibiotic of a wide range of effects, there may be a change in the intestinal microflora, which in turn will lead to a disorder of the stool and inflammation of the mucosa intestines. Talk with your doctor about the necessary measures to prevent such a condition, so as not to disturb the intestinal function. Drink sour-milk products: fresh yogurt, natural yogurt, leaven, eat home-made cottage cheese and sauerkraut.

Shelf life

The shelf life of Cedex is up to 2 years, after which it is necessary to get rid of the drug.

The finished suspension (diluted powder) can be stored for 14 days in a refrigerator.

Active substances Tsedeks

Ceftibuten

Pharmacological group

Antibiotics: Cephalosporins

pharmachologic effect

Antibacterial Wide Spectrum Action Drugs

Manufacturer

Schering-Plow Central East AG, Switzerland

ATC code

J01DD14 Ceftibuten

ICD-10 code

A02.0 Salmonella enteritis A09 Diarrhea and gastroenteritis of allegedly infectious origin A38 Scarlet fever H66 Purulent and unspecified otitis media H66.9 Otitis media unspecified J01 Acute sinusitis J02.9 Acute pharyngitis, unspecified J03.9 Acute tonsillitis, unspecified J18 Pneumonia without clarification of agent J20 Acute bronchitis J42 Chronic bronchitis, unspecified K29.5 Chronic gastritis, unspecified K52 Other non-infectious gastroenteritis and colitis N39.0 Urinary tract infection without established localization

ilive.com.ua

Antibiotics for bronchitis in children and adults

Bronchitis is a common disease that in recent years has been chronic in the population, and the signs of bronchitis in adults vary and depend on many factors.

Before the treatment of bronchitis it is necessary to find out the cause that caused the disease. Unfortunately, antibiotics for adults are prescribed empirically in adults, and in some states their purpose is completely inappropriate.

It is known that bronchitis without antibiotics is easily treated if the inflammation has a viral origin, since the virus is not treated with antibacterial agents.

If you take antibiotics during ARVI - this only interferes with the body's defense mechanisms to fight the virus, they depress immune system, lead to the development of dysbacteriosis, allergies, develop the resistance of microorganisms to the drug drug.
Depending on the type of bronchitis the doctor is prescribed the appropriate treatment:

Types of bronchitis

• Acute bronchitis

It is an inflammatory process in the bronchi that occurs most often against the background of Orvi, the flu. With a normal immune response, the body can cope with the virus and in this case antibiotics are not shown. But with the accession of a bacterial infection - pneumococci, staphylococci, streptococci, with a severe course of acute bronchitis without antibiotics is indispensable. Symptoms of acute bronchitis: purulent sputum (yellow or green) with a strong cough, temperature 3, -3, C, chest pain. The doctor prescribes expectorants, mucolytic agents for improving the excretion of sputum (bromhexine, lazolvan, chest collection), showing inhalation. With a dry, painful, unproductive cough, the anticancer preparations are shown (Sinekod, Libexin). Well helps therapeutic exercises, physiotherapy, vibrating massage. With timely and adequate treatment, the disease passes quickly, residual phenomena in the form of a cough may persist for 3-4 weeks after the illness.

• Chronical bronchitis

If the number of days of illness in two years exceeds three months, such bronchitis is considered chronic. It is distinguished by the presence of a strong cough with mucus. This can be due to smoking (see. lung cancer and smoking), occupational hazard, allergic reaction and respiratory tract infections.

Separately stands out atypical forms of bronchitis. Mycoplasmal and chlamydial bronchitis are special types of inflammation of the bronchi and lungs, which are caused by such atypical pathogens as chlamydia and mycoplasma. Recently, these bronchitis have become more often diagnosed. Mycoplasmal and chlamydial bronchitis and pneumonia develop slowly, are accompanied by intoxication, have a recurrent and protracted nature, are difficult to treat. In patients other than cough, there is a high body temperature, chills, muscle aches.

Which antibiotic is better

The table provides a choice of treatment depending on the type of bronchitis:

Types of bronchitis	additional characteristics	Treatment choice
Acute bronchitis	Viral etiology	Expectorants, Inhalation Bed rest Abundant drink Bronchitis without antibiotics
Chronic uncomplicated bronchitis	Less than 4 exacerbations per year	Aminopenicillins Macrolides
Chronic complicated bronchitis	More than 4 relapses per year, the patient's age is more than 65 years	Amoxicillin, Amoxiclav Cephalosporins Macrolides
Chronic bronchitis with concomitant diseases	The presence of chronic diseases, diabetes, kidney, heart failure	Fluoroquinolones (in resistant flora, contraindicated in children)
Chlamydia bronchitis	It develops in children and in adults with weakened immunity	Tetracyclines Macrolides Fluoroquinolones
Mycoplasma bronchitis	It develops in children and in adults with weakened immunity	Macrolides

• Aminopenicillins - first-line drugs

This is Amoxicilin (average price 50-100 rubles.), Amoxiclav (average price 250-280 rubles), Augmentin (price 120-180 rub.), Arlette (price 240-260 rubles). Such antibiotics destroy the bacterial cell walls, acting only on microbes, without harming the body. The disadvantage is that penicillins very often cause allergic reactions in patients.

• Macrolides - second-line drugs

Azithromycin (Sumamed price 540-560 rub. Azithromycin, Azitrox, Hemomycin, Z-factor, Azitrus 140 rub., Azicid, Azitral), Midekamycin (Macropen price 220-230 rubles.). Violate the production of protein in the cells of bacteria, so the microbes stop multiplying.

• Fluoroquinolones - appointed with inefficiency, allergic reactions to the first 2 rows

Levofloxacin (price 430-670 rub.), Ofloksatsin (price 30 - 170 rubles.), Moxifloxacin (Avelox price 1100-1200 rub.). Quite expensive drugs, refer to antibiotics of a wide spectrum of action, are contraindicated to children, cause dysbacteriosis, are considered to be preparations of the reserve.

• Cephalosporins

Cefazolin (10-12 rubles a bottle for 1 injection), Ceftriaxone (17-50 rubles per bottle for 1 in.), Cefalexin (capsules 40-50 rubles. for 16 pcs.), Cefixim (Suprax, Panzef, Ixim).

What is the best antibiotic for bronchitis?

This is the one to which the causative agent of the disease is most sensitive. How to determine this, and what antibiotics to drink with bronchitis? The most correct choice of a drug will be after the result of bacterial culture of phlegm on sensitivity to antibacterial agents. The disadvantage of such an analysis is the duration of the result, as well as the fact that the analysis is not done because of savings in reagents or lack of laboratories. Most often, the doctor prescribes a broad spectrum antibiotic according to the standard of treatment.

Antibiotics for children

The use of antimicrobial agents in children with colds is unacceptable, their administration is justified only in case of complication development:

• This may be the case when after the flu virus, ARVI after 4-5 days, the deterioration of the general condition of the child, the rise of high fever, a wet cough with purulent sputum. In this case, call a doctor.
• The safest and most effective drugs that can be prescribed for children are aminopenicillins and macrolides. Cephalosporins and macrolides are prescribed if there is an allergy to penicillins.
• During and after taking antibiotics, the child should take probiotic drugs in between using antibiotics, and after end of the course of treatment to continue the use of Bifiform, Rio Flora Immuno, Acipola, Bifidumbacterin, Linex for another 2-4 weeks (cm. a complete list of probiotics, analogues of Linesque).

The main rules for taking antibiotics

• Continuity of the course of treatment. The doctor evaluates the patient's condition and determines the duration of therapy, usually enough 5-7 days, with macrolide treatment - 5 days.
• Take exactly the time. It is necessary to observe the frequency of reception and maintain the same time intervals (24, 12, 8, 6 hours), that is, if an antibiotic is prescribed 3 times a day, then it is taken every 8 hours. This is necessary to maintain a constant concentration of the drug in the blood. Some antibiotics should be drunk 1 time per day (every 24 hours), others 2 (every 12 hours), some three (8 hours).
• Monitor the effect of the antibiotic. If there is no improvement within 72 hours, then the causative agent to this antibacterial agent is stable and should be changed.
• Continue treatment 2-3 days after the obvious improvement, recovery (see, for example, 11 rules for the correct intake of antibiotics).

For any malaise, cough, temperature, always consult a doctor. Distinguish manifestations of diseases, differentiate the disease, which drug should be chosen better for bronchitis and how to correctly take it, only a specialist can do it. Trust doctors, then you will not have to deal with the situation of complications from untimely or incorrect treatment, as well as with unreasonable intake of medications.

zdravotvet.ru

Antibiotic suprax - for children and adults. Instructions for use of the antibiotic suprax

Infectious diseases - an urgent problem of the present, which is faced by doctors of all specialties. However, one can not but appreciate the wide significance of antibiotics in the fight against such diseases. For a long time people have died from various infections, which now with the help of antibiotics are cured in a few days. One of the best medicines that can cure various diseases is the antibiotic Suprax. It can be used by adults and children from 6 months.

Instructions for use of the third generation antibiotic Suprap

Cephalosporin antibiotics of the 3rd generation are active against many groups of microbes. Suprax in the radar is the most effective semi-synthetic drug that destroys pathogens of infection and bacteria by suppressing them. Sensitivity to the drug shows different pathogens, which cause diseases of the kidneys, soft tissues, respiratory tract. Sometimes it can be prescribed in the treatment of mild forms of gonorrhea.

On the pharmacological market, the drug is available as a suspension for children, capsules and pellets for adults. Children are best suited for taking a suspension that has an orange or caramel flavor. Take SUPRAX should be taken once a day before meals or after, for a duration of 7 days, without interrupting the course of treatment. The daily dose should be determined by the attending physician in accordance with the patient's body weight.

From what tablets and syrup Supraks solute

Indications for use of Suprax:

• respiratory tract infections;
• diseases of the urinary system (cystitis, pyelonephritis, urethritis);
• infections of the nose, throat, ear;
• pneumonia;
• diseases of bones and soft tissues;
• a number of inflammatory processes in tonsils (tonsillitis, similar);
• pharyngitis;
• bronchitis;
• sinusitis;
• sinusitis;
• otitis and ear inflammation.

Contraindications:

• Do not use an antibiotic for an allergic reaction or for intolerance to its components;
• It is not recommended to use Suprax when breastfeeding: it is better to stop feeding while you are being treated;
• Children under 6 months of age should also not take the medicine: there are no relevant clinical studies;
• with care it is necessary to apply Suprax to the elderly, it is less often prescribed for chronic kidney disease.

Active substance

In the annotation to the drug it is written that the active active substance of the antibiotic Supraks is a cefixin. It is characterized by high efficiency, a large spectrum of antibacterial action, safety of its use in children, starting from 6 months. The cefixin is active against various microorganisms. Often it is used:

• with angina;
• respiratory tract infections;
• pharyngitis;
• sinusitis;
• acute bronchitis;
• otitis;
• gram-negative infections in children.

How and how many days to take

Before treatment, it is necessary to make an analysis for susceptibility to the antibiotic Suprax. As a rule, the drug is taken only once a day. Rules:

1. Children who are more than 12 years old (weighing more than 50 kg) and adults are prescribed Suprapax 400 mg per tablet per day. Treatment should not last more than 10 days.
2. For children, the drug is calculated based on body weight - 8 mg / kg. Take one day or once or twice 4 mg / kg with an interval of 10 hours, the course of 6 to 10 days.
3. In case of kidney diseases, the dose should be reduced.

Suspension for children

Suspension of Suprax is prescribed to babies from six months to 12 years. Breeding it is necessary from granules. To do this, you first need to shake the bottle, then add 40 ml of boiled water to it. In this case, pour in only 20 ml of water, shake the bottle, and only then add the remaining liquid. Then shake the bottle until a uniform consistency is formed. Photo of the medicine in ready form can be found on the Internet. Before each use, the suprakx bottle should be shaken well. Ready mix can be stored not in the refrigerator (no longer than 10 days). Dosage for children depends on the weight, age of the child:

from 6 months. up to a year or 4 ml;	Once a day, up to 10 days
2-4 years - 5 ml;
5-11 years - 6 or 10 ml.

Capsules for adults

Suprax for adults, as a rule, is released in the form of capsules. Take them one capsule once a day, regardless of the food intake. The course of treatment should not exceed 10 days. Often this drug is prescribed only for a week. Exceptions will be diseases that are caused by pyogenic streptococcus. The course of treatment is exactly 10 days. With kidney disease, the dose of the drug is reduced by half or a quarter, based on the level of functioning of the kidneys. Do not drink alcohol while taking medicine.

Is it possible to have Suprax during pregnancy?

It is not recommended to use the antibiotic of the third generation of Suprax during pregnancy. A physician with a serious degree of infectious disease can prescribe the drug, while assessing the possible risks for the child. Pregnant Suprax is prescribed only when the remaining antibacterial agents have not had the desired effect. In the lactation period, if you need to use the drug for a while, you should stop breastfeeding.

Side effects

There are several side effects:

• changes in blood composition;
• severe dizziness, headaches;
• vomiting, nausea, dry mouth, appetite disorders, diarrhea, bloating, dysbiosis, etc .;
• allergic reactions;
• from the side of the urinary tract - disruption of the kidneys.

Overdose of suprax can appear as an aggravation of all listed side effects. As a rule, the symptoms from the side of the stomach or intestine may be especially strong. If an overdose has occurred in the child, you need to call the hospital urgently. During the waiting period of the doctor, the patient should be rinsed with a well-ventilated stomach and given activated carbon in accordance with the body weight.

Analogs and Substitutes

Analog	Manufacturer	approximate cost
Panzef	Macedonia	200-350 rubles.
Cemidixor	China	200-300 rubles.
Ixim Lupine	India	400 rubles.
Cefix	Jordan	200-300 rubles.
Ceforal Solutab	Italy	500 r.

Before using cheap analogues of the antibiotic Suprax Solutab, one should make sure that the basic The active substance in the preparation is cefixime, and its quantity is not less than in the package of the preparation of the original. If you need to buy more packages, the total cost can sometimes be even higher than the original. Unfortunately, no Russian manufacturer offers suprax supplements.

Reviews about the medicine

Katya, 34: Suprax for a child is the fastest and most effective antibiotic. Its main advantage is that you should not drink insipid tablets, but simply dilute the suspension, which tastes like strawberry yogurt. Supraks already several times saved my children (age 5 and 7 years) with acute otitis and bronchitis.

Igor, 29 years old: I have chronic maxillary sinusitis. I tried different antibiotics: there were expensive drugs and not very much. I read the description about suprax and began to take it. What I want to note: it helps right away, the improvement comes less than a day later. When my disease is not always possible to go homeopathy, so this powerful help is just a rescue.

Irina, 38 years old: My daughter is 5 years old. After another visit to the kindergarten came home with a high fever. The local doctor determined angina, prescribed antiviral drugs first. For 4 days, the improvement did not come. The doctor decided to start drinking antibiotic Suprax. The temperature was asleep the next day.

sovets.net

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