Indinol is a selective modulator of estrogen receptors.
Non-hormonal biologically active additive, which has antiestrogenic and antiproliferative effect, which is a universal corrector of pathological hyperplastic processes in the tissues and organs of the female reproductive system (mammary gland, cervix, ovaries, endometrium and myometrium).
On this page you will find all information about Indinol Forto: full instructions for use with this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Indinol Forte. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
Selective modulator of estrogen receptors.
Conditions of leave from pharmacies
It is released on prescription.
Price list
How much is Indinol Forto? The average price in pharmacies is at the level of2 500 rubles.
Form of issue and composition
The medicine is available in packages of 30, 60, 120 pieces, and Indinol Forto - 60, 90, 120 capsules.
- The active ingredient of Indinol is indole-3-carbinol (indolcarbinol, indotriol) - a substance obtained by extraction from plants of the cruciferous family. In Indinola contains 100 mg of indole-3-carbinol per 1 tablet or capsule.
- Capsules and tablets contain the following excipients: magnesium stearate, microcrystalline cellulose, corn starch, lactose.
Pharmacological effect
The drug belongs to the group of selective modulators of estrogen receptors. This tool is a multifunctional corrector of pathological processes of a hyperplastic nature in the tissues of the mammary glands. Indinol helps to provide a positive therapeutic effect in the treatment of disorders that are provoked by excessive levels of estrogens. It is effective in the treatment of hormone-dependent epithelial tumors.
Indinol helps normalize the balance of estrogens, prevents their negative effects and blocking of hormone-independent mechanisms that activate the pathological growth of cells in the tissues of the mammary glands and uterus. The drug acts selectively and completely eliminates the transformed abnormal cells that have increased proliferative activity.
The drug helps block a number of signaling mechanisms that stimulate pathological growth of cells in the mammary glands, suppressing the signal cascades from the corresponding receptors.
Indications for use
What helps? Indigo Forto is used as part of complex treatment for tumoral and hyperplastic diseases of female reproductive and reproductive organs, in combination with other methods: surgical intervention, immunostimulation, radiation and chemotherapy.
For preventive and curative purposes, Indinol as part of complex therapy is used in women with conditions that occur against the background of hormonal disorders:
- endometriosis;
- adenomyosis;
- dysplasia of the cervix;
- premenstrual syndrome;
- ovarian cysts;
- mastopathy;
- endometrial hyperplasia without atypia;
- uterine myoma;
- papillomas on the female genitalia;
- cancers of the ovaries;
- cancers in the mammary gland;
- cervical cancer;
- papillomavirus infectious disease.
In addition, Indinol is appointed as a preventive remedy for the above diseases after surgery.
Contraindications
This drug can only be used as prescribed by the doctor after a preliminary comprehensive examination. Before you start taking the drug, you need to study the attached instructions in detail, since the capsules have serious limitations and contraindications:
- Lactase insufficiency and a symptom of malabsorption;
- Age of girls under 18;
- Individual intolerance to drug components;
- Congenital lactose intolerance;
- Period of gestation and breastfeeding.
Application in pregnancy and lactation
The drug Indinol Forto is not prescribed to women for treatment during the period of bearing a child. Data on the safety of the active ingredient on fetal fetal development are absent.
Capsules of the drug are not prescribed to patients during breastfeeding, as it is not known whether the drug penetrates into the milk and how it could affect the baby. If a woman needs therapy, she should think about stopping lactation.
Instructions for use
The instructions for use indicate that patients over 18 years of age are prescribed 1 capsule of Indinol 2 times a day. The medicine is taken before meals without opening it, washing it down with the necessary amount of liquid.
For the therapeutic effect to be obvious, the duration of the course of treatment should be at least 4-6 months. After that, take a break for several months and again repeat the course to avoid the development of a relapse of the disease.
Side effects
According to preclinical and clinical data, when taking indinol in therapeutic doses, the drug is generally well tolerated.
In individual cases, the following are possible:
- Pain in the epigastric region;
- Violations of the menstrual cycle;
- Decrease in the concentration of creatinine, eosinophilia, increased levels of prolactin, estradiol, follicle-stimulating and thyroid-stimulating hormones.
It is worth noting that the number of patients with adverse events from women receiving placebo differs only slightly - 26.9% for Indinol and 20.0% for placebo. All the revealed side effects were poorly expressed and mostly passed independently, in some cases the appointment of symptomatic therapy was required.
Overdose
In case of an overdose, diarrhea, nausea and vomiting may occur.
The specific antidote of indolcarbinol is unknown. Treatment is symptomatic.
special instructions
The duration of the course of treatment should be coordinated with the attending physician in order to reduce the development of negative consequences for the body.
Drug Interactions
Given the influence of indolcarbinol on the activity of cytochrome P450 isoenzymes, caution should be exercised when combined with medicinal drugs in the metabolism of which isoenzymes of cytochrome P450 (indirect anticoagulants, glucocorticosteroids, oral hypoglycemic drugs, antiarrhythmics, antiepileptic drugs, foxglove preparations, sex hormone preparations), t. may need to adjust their dose.
Reviews
We picked up some feedback from people about the preparation of Indinol Forto:
- Zhenya. I've been getting rid of mastopathy for a year now, and the results have only just begun to appear, since I started taking mastopol. Prior to this, I drank a few dietary supplements, I spent a lot of money, but zero sense. Mastopol costs inexpensively and I already feel that the chest does not hurt so much, although the treatment lasts only 3 weeks.
- Catherine. Indinol has applied at the insistence of a friend, she is a mammologist. The fact is that when I had a period of menstruation, my chest ached wildly. I read a lot about this on the Internet, I thought it was normal. But the girlfriend said that such a phenomenon can not be left without attention. So I started taking this drug. There were no side effects, the treatment helped. But I did not like the period of the course, it is very long. A question for the future: how can this process be accelerated?
- Jamala. I have mastopathy. Have registered indinol for two months. Saw for almost a month, then stopped, tk. stopped to go monthly. Before taking indinol, there were irregularities with the cycle, it was difficult to restore and went on regularly for three months, and after taking indinol stopped at all and there is even no sign that they will go again. Of course, I was very upset. If someone has a violation, it is better not to drink it.
Reviews about Indino Forto are contradictory. Some women write that the drug is really effective: it stops the pain syndrome with mastodynia and inhibits the growth of fibroaden, while it does not cause side effects. Others, on the contrary, indicate a lack of therapeutic effect in their case and the occurrence of undesirable reactions. Almost all patients note the high cost of the drug, which is especially noticeable when passing a full 6-month course of treatment.
Analogues
The following analogues of Indinol with the prefix Forte, produced by foreign manufacturers, which can be bought in pharmacies or online stores of dietary supplements:
- Intrinol;
- Agnukaston;
- Bromocriptine;
- Mastodinone;
- Norkolut;
- Projest;
- Cyclodinone;
- Indole Forte (produces domestic Evalar);
- NOW Foods indole-3-carbinol;
- Brest-Kare;
- Remens;
- Femsin;
- Climaton.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Shelf life - 2 years.
Keep out of the reach of children, protected from light and moisture, at temperatures up to 25 ° C.
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