Nyz tablets

Nyz is an analgesic and antipyretic drug from the group of non-steroidal anti-inflammatory drugs.

It is mainly prescribed as a symptomatic drug in the complex therapy with different conditions and diseases, accompanied by an increased body temperature, pain syndrome and inflammatory process.

The main areas of application of Naise is the therapy of osteoarthritis and osteoarthritis, as well as relief of pain syndrome of various etiologies and localization (for example, trauma, dental, menstrual pain, ear, nose, throat, etc.) and a decrease in body temperature when infections.

Clinical and pharmacological group

NSAIDs. Selective inhibitor of COX-2.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Naise cost in pharmacies? The average price in 2018 is at the level of210 rubles.

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Form of issue and composition

The main component of the drug is nimesulide. It has a good absorption, the maximum amount of it appears in the blood after 1-2 hours. It is excreted from the body almost completely through bile and kidneys.

Also the preparation includes additional elements:

• calcium phosphate;
• cellulose;
• starch (more often corn);
• talc;
• magnesium stearate;
• flavoring additives;
• aspartame;
• sodium glycolate;
• silicon dioxide (colloidal).

Nyz is round on both sides convex tablets, which include 100 mg of the main element. One blister consists of 10 pieces. It can also be produced in the form of granules for suspension, ointment or gel. All types of medicines are packed in cardboard packaging.

Pharmacological effect

Nimesulide (the active ingredient) exerts anti-inflammatory, antipyretic and analgesic effects on the human body.

Nise is effective in diseases associated with inflammation, pain and swelling. It suppresses the aggregation of platelets, and also significantly reduces bronchospasm, which is triggered by the action of acetaldehyde and histamine. In addition, Naise slows the formation of toxins and has an antioxidant effect.

Gel with topical application reduces morning stiffness, relieves swelling and weakens the pain in the joints.

Indications for use

What helps Nyz? There are many reasons for prescribing the drug. The most common:

• radiculitis;
• osteochondrosis;
• Acute lower back pain;
• Bechterew's disease;
• elevated temperature;
• defeat of joints from rheumatism;
• Rheumatoid arthritis (as well as psoriatic and other species);
• exacerbation of gout;
• pain of muscles and joints;
• bursitis (inflammation of mucous bags, often in the region of the joints);
• inflammatory processes of different origins;
• pain: headache, dental, menstrual.

Contraindications

Before starting therapy with the drug, you should carefully read the attached instructions. Nyz tablets are contraindicated in patients with the following conditions:

1. Aspirin triad;
2. Individual intolerance to the drug composition;
3. Pregnancy and the period of breastfeeding;
4. Chronic erosive processes in the organs of the digestive tract in the period of exacerbation;
5. Gastrointestinal bleeding or suspicion of it;
6. Pronounced violations of the liver and kidneys;
7. Acute hepatic or renal insufficiency;
8. Age of children under 12 years for this dosage form;
9. Atopic dermatitis or bronchial asthma.

With caution, the Nyz drug is prescribed for patients with arterial hypertension and type 2 diabetes mellitus.

Use in pregnancy and lactation

Naize can have a negative impact on fertility, pregnancy and fetal development, so the drug is not recommended for use throughout the child's gestation period, and at the planning stage pregnancy.

Also, it is contraindicated to use Naize in breastfeeding, since it is not known whether the drug is excreted into milk.

Dosage and route of administration

The instructions for use indicate that Nyz tablets should be applied at the lowest effective dose at the lowest possible short course. Tablets are taken with a sufficient amount of water, preferably after eating. If there are diseases of the digestive tract, it is advisable to take the drug at the end of the meal or after eating.

• Adults and children over 12 years - inside 1 tab. 2 times / day. The maximum daily intake for adults is 200 mg.

Patients with chronic renal failure require a reduction in the daily dose to 100 mg.

Side effects

According to reviews, Nyz may cause the following side effects when taken orally:

1. Headache and dizziness;
2. Anaphylactic shock, skin rash or bronchospasm;
3. Fluid retention, hematuria, prolonged bleeding time;
4. Heartburn, nausea and vomiting, stomach pains, erosive and ulcerative lesions of the gastrointestinal tract, diarrhea, increased activity of hepatic transaminases and toxic hepatitis;
5. Leukopenia, thrombocytopenia, anemia, or agranulocytosis.

Overdose

Overdose Naiza can lead to severe consequences and is accompanied by a violation of kidney function, hepatic insufficiency, convulsions, increased blood pressure, respiratory depression, drowsiness and apathy. Sometimes the position of the patient is aggravated by the development of gastrointestinal bleeding. When an overdose of the patient is sent to a hospital where gastric lavage is done, sorbents (Enterosgel, Polysorb, Polypefan) and osmotic laxatives will be prescribed.

To avoid overdose, follow the instructions to the drug and do not exceed the maximum allowable daily dosage. The dose of medicine for the child should be calculated by the attending physician, taking into account the body weight, age, severity of symptoms and other individual characteristics.

special instructions

Before you start using the drug, read the special instructions:

1. The drug is contraindicated in children under 12 years of age.
2. After 2 weeks of use, the control of biochemical parameters of liver function is necessary.
3. Given reports of visual impairment in patients taking other NSAIDs, treatment should be stopped immediately if any visual impairment occurs and the oculist should examine the patient.
4. Since nimesulide is partially excreted by the kidneys, its dose for patients with impaired renal function should be reduced, depending on the value of the CC.
5. Regular medical supervision is required if the patient, along with nimesulide, takes medications for which the effect on the digestive tract is characteristic.
6. The drug can cause fluid retention in the tissues, so patients with high blood pressure and with cardiac abnormalities should not be used with caution.
7. Do not use the drug simultaneously with other NSAIDs.
8. When there are signs of liver damage (pruritus, jaundice of the skin, nausea, vomiting, abdominal pain, darkening of urine, increased activity of hepatic transaminases) should stop taking the drug and consult a doctor the doctor.
9. The drug can change the properties of platelets, but does not replace the preventive effect of acetylsalicylic acid in cardiovascular diseases.

The drug may cause drowsiness, dizziness and blurred vision, so you must use caution when driving motor transport and employment by other potentially dangerous kinds of activity demanding the raised concentration of attention and speed psychomotor reactions.

Drug Interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Nimesulide is able to reduce the action of furosemide.
2. Nimesulide can enhance the action of cyclosporin on the kidneys.
3. The concentration of lithium in plasma increases with simultaneous intake of lithium and nimesulide preparations.
4. Nimesulide may increase the possibility of developing adverse reactions while taking methotrexate.
5. Due to the high degree of binding of nimesulide to plasma proteins, patients who are simultaneously treated with hydantoin and sulfanilamides, should be under the supervision of a doctor, passing the examination at short intervals time.
6. The effect of drugs that reduce blood coagulability, increases with their simultaneous use with nimesulide.
7. When used simultaneously with SCS, serotonin reuptake inhibitors increase the risk of developing gastrointestinal bleeding.

Reviews

We picked up some reviews of people who used the drug Nyz:

1. Egor. I sit at the computer very much. Tunnel wrist syndrome has worked. When unbearable I accept Nimesan. Hands cease to hurt after three minutes, and you can continue.
2. Nastya. "Nyz" I use with severe pain, my family "is familiar" with him not by hearsay. I first used it when the wisdom tooth was removed. The result is excellent and the effect persists for a long time. One day I could not take the pill on time, the pain began to roll in waves. I heard that it is much more difficult to cope with pain, but Naize helped and quickly enough. Still seldom, but I accept at a strong headache, when tsitramon does not help or assist. And the last time my husband shot a back, the pain was very strong - could not get up. Too first of all gave him "Nyz and after that she rubbed her back.
3. Valentina. During menstruation, I did not know where to put myself. I tried a lot of drugs. They gave effect, but not the way I would have liked, and after a while the pains began again. Once I went to the pharmacy, I did not find those painkillers that I always took. The pharmacist advised me to take Naise. There was nowhere to go, and I agreed. But I do not regret my purchase at all. I expected this result from other pills.

Analogues

Structural analogs for the active substance:

• Actasulide;
• Amoeolin;
• Aponil;
• Aulin;
• Coxtral;
• Mesulide;
• Nemux;
• Nimegesic;
• Nimesil;
• Nimesulide;
• Nimesulide-Pharmaplant;
• Nimika;
• Nimulid;
• Novolide;
• Prolid;
• Sulaydine;
• Fllolid.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store the product at home in a place where there is no high humidity, at a temperature of no more than 25 ° C. The storage location must be protected from bright sunlight.

Shelf life of the drug is not more than 3 years. Use after the end of the specified periods of the drug is prohibited.

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