Neurodictivitis

Anti-inflammatory non-steroid drugs work more effectively in combination with group B vitamins. Neurodiclavitis is a complex medication containing both of these ingredients.

Thanks to this combination of active substances, pain caused by neurologic, locomotor (sometimes gynecological and otolaryngic) diseases is reduced.

Currently, the Neurodiclavitis is available in the form of capsules for oral administration. There are regular capsules and capsules with modified release of active substances, but this difference is not is too important, since both versions of the same dosage form are administered according to the same rules.

Clinical and pharmacological group

NSAIDs in combination with group B vitamins.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Neurodicoid in pharmacies? The average price is at the level of290 rubles.

Form of issue and composition

Neurodiclavitis is released in the form of capsules with modified release. The main constituent components of one capsule are:

instagram viewer

Vitamin B12 (cyanocobalamin) - 250 mcg;
Vitamin B6 (pyridoxine hydrochloride) - 50 mg;
Vitamin B1 (thiamine hydrochloride) - 50 mg;
Sodium diclofenac - 50 mg.

Auxiliary components: talc, triethyl acetate, copolymer of ethyl acrylate and methacrylic acid, povidone K25. Sell Neurodiclavitis in blisters for 10 capsules.

Pharmacological effect

Neurodiclavitis is an NSAID, which includes vitamins of group B. The active substance of the drug diclofenac produces an anti-inflammatory, analgesic, antiplatelet and antipyretic effect. It is the anti-inflammatory and analgesic properties of the drug that helps minimize pain, eliminate morning stiffness and swelling of the joints in rheumatic diseases. This complex effect of the drug makes it possible to improve the functionality of the joint.

The therapeutic effect of diclofenac is also effective in the post-operation period and in trauma.

In turn, they have a therapeutic effect and vitamins:

Thiamine (B1). Participates in carbon, lipid, energy and protein metabolism, regulates the activity of the nervous system (in particular, it is responsible for the mechanism of conduction of a nerve impulse).
Pyroxidine (B6). It improves the contractility of the heart muscle, promotes the conversion of folic acid into an active form. Also, vitamin is involved in the synthesis of neurotransmitters, regulates the work of the nervous system, promotes the absorption of glucose by nervous cells, reduces spasms and muscle cramps, improves the passage of a pulse from the receptors to the brain. In addition, pyroxidine synthesizes neurotransmitters such as dopamine, serotonin, noradrenaline, epinephrine, histamine.
Cyanocobalamin (B12). Participates in the hematopoietic process, the formation of neurons, positively affects the metabolism, synthesizes the nucleic acids necessary for the normal functioning of the nervous system.

Indications for use

What is the use of Neurodiclavitis? It is prescribed for the following diseases:

Acute gouty arthritis;
Neuritis (inflammation of the occipital, intercostal or facial nerve, as well as the nerves of the limb) and neuralgia (severe pain along the innervation of the nerve - sciatica, lumbago, trigeminal attack);
Inflammatory and degenerative-dystrophic pathologies of the ridge and bone articulations, accompanied by a pronounced pain and inflammation (osteochondrosis, spondylarthrosis, osteoarthritis, polyarthritis of chronic form);
Rheumatic extraarticular lesion of periarticular tissues.

Also, the drug is prescribed if there is a pronounced pain syndrome after an operative or dental introduction, with painful menstruation, sore throat, caused by tonsillitis, tonsillitis, pharyngitis.

Contraindications

The use of Neurodiclovitis is contraindicated in such cases:

The period of pregnancy and breastfeeding;
Active liver disease;
Hemostasis disorders;
Hyperkalemia;
Intracranial bleeding;
Bowel diseases of inflammatory nature;
Violations of hematopoiesis;
Gastrointestinal bleeding;
Childhood;
Severe heart failure;
Hypersensitivity to individual components of Neurodiclavitis and other NSAIDs;
Erosive-ulcerative lesions of the gastrointestinal tract, which are in the phase of exacerbation;
Progressive kidney disease and severe renal failure;
Incomplete or complete combination of bronchial asthma, intolerance to acetylsalicylic acid and other NSAIDs and recurrent polyposis of paranasal sinuses or nasal mucosa;
Period of aortocoronary bypass surgery.

According to reviews, Neurodiclovitis should be administered with caution when:

Bronchial asthma;
Chronic renal failure;
Diseases of peripheral arteries;
Diabetes mellitus;
Alcoholism, smoking and other addictions;
Ulcerative colitis, stomach ulcer and duodenum;
Diseases of the liver;
Diseases of Crohn;
Chronic liver failure, hepatic porphyria;
Arterial hypertension;
Chronic heart failure;
Simultaneous administration of antiaggregants, anticoagulants, GCS, selective serotonin reuptake inhibitors;
Cerebrovascular diseases;
Ischemic heart disease.

Use in pregnancy and lactation

In view of the lack of clinical experience and unconfirmed drug safety for intrauterine development of the fetus, the use of Neurodiclovitis during pregnancy is contraindicated. If the woman took the drug and became pregnant, the treatment should be stopped immediately and consulted by a gynecologist.

Since the active ingredients are excreted in breast milk, the drug is not recommended during breastfeeding, if necessary, a woman should stop lactation.

Dosage and route of administration

The instructions for use indicate that Neurodiclavitis capsules should be taken orally during meals, with a sufficient amount of liquid. For adults, the dosage is 1 capsule three times a day at the initial stage of treatment, and as a maintenance therapy - 1 capsule 1-2 times a day.

The duration of treatment depends on the severity and nature of the disease.

Side effects

In some cases, there may be side effects when using the drug "Neurodiclavitis." Indications for use and recommended dosages sometimes do not bring the desired result. Conversely, some patients after receiving the above drug complain of the occurrence of unpleasant sensations and conditions:

from the respiratory system: cough, pneumonitis, bronchospasm, laryngeal edema;
on the part of the digestive tract: diarrhea or constipation, abdominal pain, nausea, peptic ulcer with various symptoms of complications, flatulence, dry mucous membranes, sensation of bloating, aphthous stomatitis, gastrointestinal bleeding, liver necrosis, vomiting, hepatorenal syndrome, liver cirrhosis, appetite changes, cholecystopancreatitis, colitis, pancreatitis;
from the nervous system: dizziness, drowsiness, sleep disturbances, headaches, irritability, depression, general weakness, convulsions, disorientation, a sense of fear, aseptic meningitis, nightmarish dreams;
from the senses: blurred vision, scotoma, taste disorder, diplopia, tinnitus;
from the genitourinary system: fluid retention, oliguria, proteinuria, hematuria, nephrotic syndrome, papillary necrosis, renal failure (acute), azotemia;
from the heart: increased arterial pressure, chest pain, heart failure (congestive), myocardial infarction.

In addition, there may be:

anaphylactic shock, edema of the tongue and lips, anaphylactoid reactions, allergic vasculitis;
skin rash or itching, erythema multiforme exudative urticaria, toxic dermatitis, eczema, increased photosensitivity, toxic necrolysis epidermal, small-point hemorrhage, alopecia.

It is very important to take into account when using the drug "Neurodiclovitis" indications for use and not only. In no case should we not pay attention to the above side effects. If these symptoms are observed, the patient is recommended to stop using the drug "Neurodiclovitis". The experts' opinions contain advice that such a patient should always seek qualified medical help.

Overdose

In case of an overdose, the following symptoms appear: vomiting, bleeding from the gastrointestinal tract, epigastric pain, diarrhea, dizziness, tinnitus, lethargy, convulsions; rarely - increased blood pressure, acute renal failure, hepatotoxic effect, respiratory depression, coma.

As treatment, gastric lavage, activated charcoal, symptomatic therapy directed to eliminate the increase in blood pressure, violations of kidney function, seizures, irritation of the gastrointestinal tract, respiratory depression.

special instructions

Before you start using the drug, read the special instructions:

During the reception of the drug is not recommended the use of multivitamin complexes, which include vitamins of group B.
During the treatment with the drug should be a systematic control of the picture of peripheral blood, liver function, kidneys, examination of feces for the presence of blood.
In order to quickly achieve the desired therapeutic effect, the tablets are taken 30 minutes before meals. In other cases, take before, during or after eating, without chewing, squeezed with enough water.
To reduce the risk of developing adverse events from the gastrointestinal tract, the drug should be applied at the lowest effective dose with the minimum possible short course.
If, during the administration of the drug, an increase in the activity of hepatic transaminases persists or increases if clinical symptoms of hepatotoxicity (including nausea, fatigue, drowsiness, diarrhea, pruritus, jaundice) treatment should be discontinued.
Diclofenac (like other NSAIDs) can cause hyperkalemia.
Because of the important role of prostaglandins in maintaining renal blood flow, care should be taken when prescribing to patients with cardiac or renal insufficiency, treatment of elderly patients receiving diuretics, and patients who for any reason have a decrease in BCC (including after extensive surgery). If in such cases diclofenac is prescribed, then as a precautionary measure it is recommended to monitor the kidney function.

Drug Interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

Diclofenac enhances the effect of drugs that cause photosensitivity.
Drugs that block tubular secretion, increase the concentration in the plasma of diclofenac, thereby increasing its toxicity.
Neurodiclavitis reduces the antiparkinsonian efficacy of levodopa.
Ethanol dramatically reduces the absorption of thiamine (blood levels may drop by 30%).
Long-term treatment with anticonvulsant drugs can lead to a thiamine deficiency.
The use of colchicine and biguanides reduces the absorption of cyanocobalamin.
With the simultaneous use of Neurodiclavitis reduces the effect of diuretics, against the background of potassium-sparing diuretics, the risk of hyperkalemia increases.
With the simultaneous use of Neurodiclavitis increases the concentration in the plasma digoxin, methotrexate, lithium and cyclosporine.
With the simultaneous use of Neurodiclavitis reduces the effects of hypotensive and hypnotics.
With simultaneous application of Neurodiclavitis increases the likelihood of side effects of other NSAIDs and GCS (gastrointestinal bleeding), toxicity of methotrexate and nephrotoxicity of cyclosporine.
Acetylsalicylic acid reduces the concentration of diclofenac in the blood.
Simultaneous use of Neurodiclavitis with paracetamol increases the risk of developing nephrotoxic effects of diclofenac.
With the simultaneous use of Neurodiclavitis reduces the effect of hypoglycemic agents.
When used simultaneously with Neurodiclovitis, cefamandol, cefoperazone, cefotetan, valproic acid and plikamycin increase the incidence of hypoprothrombinemia.
Cyclosporine and gold preparations increase the effect of diclofenac on the synthesis of prostaglandins in the kidneys, which increases the risk of developing nephrotoxicity.
Simultaneous appointment of Neurodiclovitis with ethanol, colchicine, corticotropin, inhibitors of the inverse seizure of serotonin and preparations of St. John's wort increases the risk of developing gastrointestinal bleeding.
With the simultaneous use of Neurodiclavitis and anticoagulants, thrombolytic agents (alteplase, streptokinase, urokinase) increases the risk of bleeding (more often gastrointestinal bleeding).

Reviews

We picked up some reviews of people who used the drug Neurodiclavitis:

Yuliya.Also familiar with these tools. Because of not passing pains in a neck to me appointed or nominated Nejrodikiklovit to accept. Diclofenac and B vitamins gradually helped to get rid of the pain. And now after the termination of that course of treatment I drink Neuromultivitis. It also contains vitamins like Neurodiclovitis, only dosage is more. The pains stopped worrying.
Oksana. Neurodiclavitis contains diclofenac and B vitamins. Due to this combination, you can take a lower dosage of diclofenac. But the effect will be as of the full dose, since the vitamins of group B potentiate the action of diclofenac. The drug is given for three or five days. Then you need to switch to the supporting course neuromultivitis.
Pauline. Currently, I take Neurodictivitis just. The doctor has appointed or nominated at pains in a neck. I feel pretty good already, although before that I could not even turn my head because of pain. By the way, the doctor warned that after the course of this drug, Neuromultivitis will take to restore the tissue of the nervous. Yes, I am only FOR - as for me, any treatment should be comprehensive, so as not only to eliminate the symptoms of the disease, but also to influence the cause of their occurrence. Then there will be no problems with well-being.

Analogues

Unfortunately, Neurodiclovitis does not have analogues in terms of active substances. That is, other drugs that contain B vitamins and diclofenac simultaneously, on the pharmaceutical market of the CIS countries there. Therefore, the closest analogues of Neurodiclovitis are medicines containing only diclofenac as an active substance, since they have the most similar therapeutic effect.

So, analogues of Neurodiclovitis in the domestic pharmaceutical market are the following drugs:

Alvipsal;
Apizarthron;
Acylpyrine;
Bengay;
Betalgon;
Bralangin;
Brufen;
Voltaren;
Voltaren Emulgel;
Dexalgin;
Diklobene;
Diqlovit;
Dicloran;
Diclofenac;
Diprospan;
Dolgit;
Indomethacin;
Adhesive plaster medical Nanoplast forte;
Maxigan;
Nyz;
Neuromultivitis;
Nimesulide;
Niflugel;
Pliwalgin;
Rapten Duo;
Revalgine;
Sanaprox;
Spasgan;
Spazmalgon;
Surgham;
The Texman;
Tenoktil;
Fastum gel;
Finalgon;
Flamadex;
Flamax;
Fleksen;
Cefexon;
Efkamon;
Yunispaz.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Capsules should be kept away from children in a cool dry place, avoiding direct sunlight on the drug. Shelf life of the medicine is 3 years from the date of production, after the end of this period the drug should not be taken inside.