Vazonit: instructions for use, reviews and price

Vazonite belongs to the pharmacological group of angioprotectors.

It stabilizes the microcirculatory vascular system and normalizes the permeability of its walls. This is achieved by lowering the viscosity of the blood and dilating the lumen of the vessels. In addition, the medicine prevents the process of thrombosis due to increased resorption, both clots and already formed blood clots.

On this page you will find all information about Vazonit: the full instruction on the application for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Vazonite. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that improves microcirculation. Angioprotector.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Vazonite? The average price in pharmacies is at the level of450 rubles.

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Form of issue and composition

Vazonite is available in the form of long-acting tablets coated with a film membrane. Tablets are oblong, biconvex and white, the risks are located on both sides.

• The film sheath includes: macrogol 6000, titanium dioxide, talc, hypromellose and polyacrylic acid.
• The main active substance of the drug is pentoxifylline. Auxiliary components are represented by hypromellose, crospovidone, microcrystalline cellulose, magnesium stearate and colloidal silicon dioxide.

Tablets Vazonite are produced in blisters for 10 pieces, in a cardboard bundle two blisters.

Pharmacological effect

Vazonite improves microcirculation and rheological properties of blood, has a vasodilating effect. As active substance contains pentoxifylline - a derivative of xanthine. The mechanism of action is associated with the inhibition of phosphodiesterase and the accumulation of cAMP in the cells of the smooth muscles of the vessels, in the blood constituents, in other tissues and organs.

The drug inhibits the aggregation of platelets and erythrocytes, increases their elasticity, reduces the level fibrinogen in the blood plasma and enhances fibrinolysis, which reduces the viscosity of the blood and improves its rheological properties. Improves the supply of oxygen to tissues in areas of impaired blood circulation, in particular, in the limbs, the central nervous system, and, to a lesser extent, in the kidneys. Slightly dilates the coronary vessels.

Indications for use

The drug is prescribed for the following diseases and conditions:

1. Hearing disorders of vascular genesis, accompanied by hearing loss;
2. Violations of cerebral circulation of the ischemic type (ischemic cerebral stroke);
3. Violations of peripheral circulation (obliterating endarteritis, diabetic angiopathy, Raynaud's disease);
4. Atherosclerotic and dyscirculatory encephalopathy, angioneuropathy;
5. Disturbances in the blood circulation of the eye (acute, subacute and chronic circulatory insufficiency in the retina or in the choroid of the eye);
6. Trophic changes in tissues due to violation of arterial or venous microcirculation (postthrombophlebitic syndrome, varicose veins, trophic ulcers, gangrene, frostbites).

Contraindications

According to the recommendations, the drug should not be taken to patients with hypersensitivity to constituent components, nor should it be taken to people who have suffered the following pathologies

• large blood loss;
• with hemorrhages in the retina of the eye;
• myocardial infarction in acute form;
• in the presence of an acute stroke with cerebral hemorrhage.

It is also recommended to take with extreme caution in the presence of the following diseases and conditions:

• in the presence of gastric and duodenal ulcers;
• with ulcerative lesions of the intestine;
• heart failure;
• atherosclerosis;
• with reduced arterial pressure;
• when the body is prone to severe bleeding.

Application in pregnancy and lactation

The use of the drug Vazonit during pregnancy and during breastfeeding is contraindicated.

Instructions for use

The instructions for use indicate that the vasonite in the form of tablets should be taken orally, without chewing and squeezed with enough liquid, preferably after eating.

1. Usually appoint 1 tab. (600 mg) 2 times / day (morning and evening). The maximum dose is 1.2 g.
2. Duration of treatment and dosing regimen is set by the doctor individually depending on the clinical picture of the disease and the therapeutic effect obtained.

In patients with severe impairment of liver function, a dose reduction with regard to individual tolerability is necessary.

In patients with chronic renal failure (CC less than 30 ml / min), the daily dose is reduced to 600 mg.

In patients with low blood pressure, as well as in patients at risk for possible lowering of blood pressure (patients with severe CHD or with hemodynamically significant stenoses of cerebral vessels), treatment can be initiated by small doses. In these cases, the dose can be increased only gradually.

Side effects

And reviews about Vazonite, and doctors note such side effects from various body systems, such as:

1. From the side of the central nervous system: headache and dizziness, as well as sleep disturbance, anxiety, although such phenomena occur rarely;
2. From the gastrointestinal tract: loss of appetite, diarrhea, nausea and vomiting, epigastric pain, feeling of overflow in the abdomen;
3. On the part of hemopoiesis and blood coagulation systems: bleeding in the mucous membranes, skin, gastrointestinal tract, as well as aplastic anemia, thrombocytopenia. During the administration of the Vasonitis, regular monitoring of the blood condition is required;
4. From the side of the cardiovascular system: tachycardia, hyperemia of the face, lowering of arterial pressure, stenocardia, disturbance of the heart rhythm - these symptoms occur with high doses of the drug;
5. Allergic reactions: skin rash, itching, hives, anaphylactic shock (extremely rare), angioedema.

Overdose

Symptoms of overdose include weakness, dizziness, low blood pressure, tachycardia, drowsiness, redness of the skin, loss of consciousness. There may also be chills, areflexia, tonic-clonic convulsions, vomiting "coffee grounds".

When signs of an overdose show gastric lavage and the subsequent reception of activated charcoal. When vomiting with traces of blood, rinsing is contraindicated. Further, symptomatic therapy is carried out, including maintaining the function of respiration and stable pressure. Cramps show diazepam.

special instructions

1. Smoking reduces the therapeutic efficacy of the Vasonitis. Also during the treatment should not drink alcoholic beverages.
2. During drug therapy, blood pressure should be monitored. With diabetes and the use of hypoglycemic agents Vazonite in high doses can cause the development of hypoglycemia.
3. In case of a hemorrhage in the retina of the eye as a result of the use of Vasonitis, it should be immediately stopped.
4. Patients who have recently undergone surgical intervention and who have been assigned Vazonitis should be systematically monitored for hematocrit and hemoglobin.
5. With the simultaneous use of vasonitis and anticoagulants, it is necessary to observe the parameters of the blood coagulation system.

Since vazonite can cause dizziness, it is advisable to use caution when controlling potentially dangerous mechanisms that require increased concentration of attention.

Drug Interactions

Pentoxifylline potentiates the action of antihypertensive drugs, insulin, oral hypoglycemic drugs, theophylline, heparin, fibrinolytic agents.

Reviews

We picked up some of the people's opinions about the drug Vazonit:

1. Jeanne. Vazonite is an excellent vasodilator. I'm satisfied with them 100%! I had an ischemic stroke 3 years ago, now almost recovered, and all thanks to these pills! In addition to everything else, the pressure also decreased.
2. Andrei. I take the drug in connection with the violation of the blood circulation of the brain and as a result I constantly want to sleep. I drive a car, there are no problems, the reaction is not dull.
3. Anita. Dyscirculatory encephalopathy, this diagnosis was put to me by the doctors after the examination, in simple terms - the deterioration of the blood supply to the brain tissue. They prescribed complex treatment, among other medications recommended "Vazonit". The medicine is well tolerated. There were no side effects. After drinking it for a long time, I felt better. Dizziness stopped, it became better with memory, absentmindedness, energy appeared. In the meantime, the pressure normalized. In order to prevent it I take it 2 times a year. I feel good.
4. Valentina. I have a long trophic ulcer, I've been drinking Vazonite long enough. There are changes - the surface of the ulcer narrowed, although not significantly, but most importantly - the wound became less deep! Well and in general, I with this preparation only began to sleep worse, special improvements as there was no, and no.

Analogues

The structural analogues of the Vasonitis include such medicines as:

• Pentylin;
• Trental;
• Flexitale;
• Agapurin;
• Pentoxifylline;
• Trenpental.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Shelf life - 5 years. Store at a temperature of no higher than 25 ° C in a dry, protected from light and out of reach of children.

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