Doctors prescribe Drimin's medication to relieve nausea and vomiting in sea and aerial phobia. The drug perfectly copes with motion sickness in transport and stops vomiting.
The agent can be used after radiation therapy to relieve unpleasant symptoms. Sometimes it is prescribed after taking medications that cause nausea. As a symptomatic therapy used in the disease Meniere. Excellent for patients with impaired vestibular apparatus.
On this page you will find all the information about Dramin: a full instruction on the application to this medication, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Dramina. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
The blocker of histamine H1 receptors with anticholinergic properties.
Conditions of leave from pharmacies
It is released on prescription.
Price list
How much does Dramina cost? The average price in pharmacies is at the level of220 rubles.
Form of issue and composition
Dosage form: tablets: round flat, with a facet and separation risk on one side, white (5 or 10 pcs. Each). in blisters, in a cardboard bundle 1 blister).
- The main active ingredient of the drug is dimenhydrinate, one tablet contains 50 mg of active substance.
- As auxiliary components are: magnesium stearate, povidone, lactose, microcrystalline cellulose.
Pharmacological effect
The active substance of the drug - dimenhydrinate, is able to block H1 histamine and acetylcholine muscarinic receptors of the central nervous system. First of all, getting into the body, Dramina affects otoliths, due to which vestibular stimulation is suppressed, and in high doses the drug acts on semicircular canals.
The drug has a sedative, moderate anti-allergic and mildly expressed local anesthetic effect. After oral administration, the drug is well absorbed from the gastrointestinal tract. Antiemetic action begins 15-30 minutes after taking the drug. The effect lasts for 3-6 hours. The drug is well distributed in the tissues of the body, easily binds to plasma proteins.
With prolonged use of the drug, the development of tolerance to dimenhydrinate is possible, as a result of which, first of all, the severity of the antiemetic and sedative effect, while the antihistamine action is fully preserved.
Indications for use
What helps? According to the instructions, Dramin is applied:
- With Meniere's disease;
- In sea and air sickness;
- In order to prevent and eliminate the symptoms of labyrinthine and vestibular disorders (nausea, dizziness, vomiting), other than those caused by antitumor therapy of symptoms.
Contraindications
Before starting therapy with Drimine, patients should carefully study the accompanying instructions, since the tablets have a number of the following contraindications:
- Epilepsy;
- Dermatoses;
- Age in children up to 12 months;
- Pregnancy and lactation;
- Individual intolerance to the components of the drug.
Application in pregnancy and lactation
Dramina during pregnancy is categorically contraindicated. The composition can damage the health of the mother and cause complications. Doctors forbid to feed the baby with a breast and in parallel to take the drug. The components of the drug through the milk will enter the child's body and lead to dangerous consequences.
Instructions for use
The instructions for use indicate that the tablets should be taken orally before meals. Recommended dosages and dosage regimens:
- For prevention of motion sicknesstake one or two tablets 30 minutes before the trip.
- As a prophylactic and for the elimination of symptoms of vestibular and labyrinthine disorderschildren from 3 to 6 years are prescribed from 0.25 to 0.5 tablets 2 or 3 times a day; children from 7 to 12 years - 0.5 tablets or 1 tablet 2-3 times a day; children from 12 years and adults - 1-2 tablets 2-3 times a day;
- In sea and air sicknessdose for children from 3 to 6 years is from 0.25 to 0.5 tablets 2-3 times a day; children from 7 to 12 years are given half pills 2-3 times a day; dose of Drama for children over 12 years and adults - 1-2 tablets 2 or 3 times a day;
- With Meniere's diseaseChildren under the age of 12 are given 0.5-1 tablets 2-3 times a day, children over 12 years of age and adults - 1-2 tablets 2-3 times a day;
The maximum daily dose of the drug for adults is no more than 7 tablets. In this case, the duration of Drumina and the possibility of a second course of treatment should be determined by the doctor.
Side effects
- From the cardiovascular system: a decrease in blood pressure, tachycardia.
- On the part of the digestive system: dry mouth, decreased appetite, nausea, vomiting.
- From the respiratory system: dryness of the mucous membranes of the nose, thickening of the bronchial secretion.
- Allergic reactions: skin rash, angioedema, bronchospasm, drug dermatitis.
- From the side of the central nervous system: dizziness, headache, drowsiness, general weakness, fatigue, impaired concentration, anxiety, nervousness, insomnia; rarely - the weakening of night and color vision, a violation of accommodation.
- Other: hemolytic anemia, difficulty urinating.
Overdose
An overdose of the drug manifests dryness in the mouth, throat, nasal cavity, retardation and difficulty breathing, confusion, red face, convulsions and hallucinations (in childhood). In such situations, the patient is shown gastric lavage with activated charcoal, saline laxative and symptomatic therapy. Children with convulsions are prescribed phenobarbital and diazepam.
special instructions
- During the treatment should be avoided the use of alcohol.
- Patients taking dimenhydrinate should avoid practicing potentially dangerous activities that require increased attention and speed of psychomotor reactions.
- With caution apply dimenhydrinate in closed-angle glaucoma, urinary disorders, benign hyperplasia of the prostate, epilepsy, in patients with severe cardiovascular diseases.
Drug Interactions
In combination with sedatives, hypnotics, antidepressants, ethanol, the depressing effect on the central nervous system increases.
Dimenhydrinate may mask the ototoxicity of streptomycin and some other antibiotics of aminoglycosides.
Reviews
We picked up some of the people's comments about the Drameen drug:
- Larissa. I have been in transport since childhood. Decided to hedge before a long trip and bought a tablet of "Dramina", drank a few minutes before the start. The pressure fell. Nausea was not, but felt so bad that it would be better to nausea. I do not fit these pills.
- Aziza. From childhood, the incomprehensible intolerance of buses, and sometimes even cars, was constantly aggravated, distant trips were terrible, a constant feeling of nausea. My mother advised me to try Drumina many years ago. A good drug, it helps uniquely, the main thing is to drink earlier, about 30 minutes before the trip, flight. But really a big minus is that the side effect of his sleeping pills. In a dream it makes you feel terrible, even if you were alert before using it. But if you want to get some sleep on the way, but do not chat as I plan every time, then this is the most necessary means of motion sickness 😉
- Daria. Sometimes you have to fly by airplane, and since I'm very hard on the plane, I take these pills. I drink one forty minutes before takeoff. One tablet lasts about 6 hours. If I feel in the airplane that the effect of the pill ends, then I drink one more. "Dramina" really helps a lot to get rid of the feeling of nausea. From these pills very much tends to sleep, but this is not a problem, because during the flight and so usually you want to sleep, especially if it is a night voyage. The most important side effect for me is dry mouth. It's really unpleasant, but it's better than nausea.
Analogues
The analogue of the agent for the main active ingredient is Ciel. Analogues of Dramin tablets, similar in mechanism of action, as well as belonging to one farmgroup, include:
- Alerpriv;
- Histafen;
- Diazoline;
- Kestin;
- Lomilan;
- Peritol;
- Rapido;
- Semprex;
- Telfast;
- Fexadine;
- Erius.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Keep the tablets away from sunlight at an optimum temperature of +25 degrees. Store the drug in an inaccessible place for children so that there is no overdose.
Shelf life of the medicine is 5 years from the moment of manufacture. At the end of the period, you can not take pills.
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