Review of antiviral drugs in cases of influenza and influenza
Any disease, especially ARVI and the Flu is easier, cheaper and safer not to treat, but not to prevent, to prevent its occurrence. Recently, especially worried about the "point" - it's safer. Should I take antiviral pills at all? In today's complex world, how to understand the issues:
- Will the effect of using an expensive antiviral drug?
- Which drug is better for adults to take flu, children?
- Do not it cause harm to health?
- Is there the best cure for flu?
- Effective antiviral drugs - is it advertising, business, dummy or not?
Antiviral drugs for Orvy on the Russian pharmaceutical market are as follows:
Virtually all antiviral drugs for orvi and flu have no evidence base for their antiviral efficacy. Studies are very expensive, conducted by the manufacturers themselves and those interested in the positive conclusion of the parties. Today, most clinical trials of new drugs are regularly falsified in order to bring "miraculous" drugs to the market with a new price tag. Given the fabulous commercial benefits of selling expensive antiviral drugs during the epidemic, honesty and objectivity of research is not believed. As you know, pharmacological publications, even in medical journals today, are about 90 percent - these are custom-made articles of an advertising nature.
Today in the pharmacy chains an abundance of various medicines, some of which in fact "Medicines" are not, because there are a lot of fakes, frank dummies and inefficient means. Advocates of patients' rights in Ukraine, for example, argue that in 4 drugs registered as antiviral - the active substance was not found. However, a wide advertising company allows producers to earn millions of hryvnias on them per year.
Antiviral drugs for Orvi are conventionally divided into:
- Vaccines - stimulation of the production of antibodies before infection with the virus
- Immunostimulants - drugs that temporarily enhance nonspecific immunity, which promote the production of interferons
- Antiviral drugs are agents that affect neuraminidase (a viral enzyme) by suppressing the multiplication of the virus (Oseltamivir, Zanamivir) and blockers of M2-channels Amantadine, Remantadin - these drugs have proven clinical effectiveness, but as any means have a number of side effects effects.
Most antiviral drugs for orvi and influenza are developed and applied no more than 10-40 years. The drug should have a greater "trial period" in order to draw a conclusion about its effectiveness and side effects. As for immunostimulants, these funds can have delayed consequences (development risks autoimmune diseases, oncological diseases of the blood, etc.) and should be prescribed according to strict indications.
Immunity modulators and antiviral agents
The immunostimulants produced today show the activation of immune reactions at the biochemical level (what is called "In vitro"), but their real benefits and long-term consequences of use are rather complex, poorly understood region. Since information on many mechanisms of immunity has become known relatively recently, scientists are getting more and more information about its functioning every year. Therefore, there is no confidence in the safety and correctness of general stimulation of the "under-researched" immune system (see Fig. what is immunity and whether drugs are needed to improve it). Especially prudent should be the preventive use of immunostimulants and the treatment with antiviral medicines for children.
"Pharmacy immunostimulants can not only help the body, but also harm" - says Ph.D. Tatyana Tikhomirova, immunologist-allergist. Such a state as hyperactivation of the immune system, as well as immunodeficiency is extremely dangerous, the human body functions normally only with the balance of the immune system. And if a person each time stimulates ("to increase self-immunity"), then, in the presence of predisposing factors, this may result in pathological inflammation, launching of immune aggression on healthy tissues, hyperactivation of the immune system and theoretically (in extreme cases) to the development of autoimmune or oncological disease.
If the next of kin has any autoimmune disease (rheumatoid arthritis, insulin-dependent sugar diabetes, Sjogren's syndrome, multiple sclerosis, etc.), then under no circumstances should a person use any immunostimulants. Even if a person is healthy, there is already a violation of the immune system, and one can live with them all his life, but if he is rude and persistently try to stimulate their immune system, it can end with the debut of an autoimmune disease.
Fortunately, for most healthy people, without the presence of any predisposing factors, it is difficult to "achieve" your immunity so as to seriously damage your health. Since most of the known immunostimulants either do not work at all, or almost do not work. One part of the drugs - an ordinary deception, another - ineffective means. But it should be remembered that any drug has side effects.
| Drug Groups | Act | Names of drugs |
| Interferon preparations | Blockade of viral mRNA translation, presentation of viral antigens | Recombinant alpha / gamma interferons |
| Etiotropic means | Neuraminidase inhibitors |
|
| Ion channel blockers | Rimantadine (Remantadin, Orvirem) | |
| Antiviral drugs with varying degrees of evidence of action | Enabling synthesis endogenous interferons |
|
| Specific HA chaperone |
|
|
| NP-Protein Inhibitors |
|
Alexander Khadzhidis, Chief Clinical Pharmacologist, St. Petersburg states the following: "Some doctors for some reason first appoint patients antipyretic drugs, and then immunomodulators, supposedly for the production of interferon - which is illogical and generally is absurd. That is, first, knocking down the temperature - "forbid" the body to fight the virus (at high temperature, antibodies are produced against the virus and infection), and then artificially "forced" do.
In developed countries, interferonogens (drugs that stimulate the production of interferon) are not at all. Interferons can work only with parenteral (intravenous) administration, and even then, their effectiveness is questionable. In Russia, these drugs are extremely popular, despite the fact that they are useless.
With regard to antipyretics with the virus - to knock down the temperature better with paracetamol and once with a rise in temperature, rather than 4 p / day - "just in case." Taking Aspirin (acetylsalicylic acid) in ARVI, especially in children under 12 years old, is contraindicated, it can become the cause of severe damage to the central nervous system and the liver, it is not recommended to apply it to those who suffered from peptic ulcer disease Gastrointestinal tract. "
Well-known in Russia doctor Alexander Myasnikov says that all immunomodulators widely advertised in our country are a waste of money. In the United States and Western Europe, it is already unequivocally recognized and proven that these remedies are ineffective, but most Russian doctors continue to believe in the power of immunomodulators in treating Orvi.
Cytovir 3
Pharmacological action: Integratedimmunostimulating, an antiviral drug,
has an interferonogenic effect. As part of the drug - Timogen sodium, ascorbic acid, bendazole. Timogen synthetically obtained dipeptide, it enhances the nonspecific resistance of the organism. Ascorbic acid normalizes the permeability of capillaries, reducing the activity of the inflammatory process. Bendazol stimulates the production of endogenous interferon in the body.Side effects: in people suffering from vegetative-vascular dystonia, causes a decrease in blood pressure.
Contraindications: in pregnancy, children under 1 year, thrombophlebitis, severe hypotension, diabetes mellitus, stomach ulcer, urolithiasis.
Issued: since 2001 in capsules, for children since 2006 in syrup, in powder for the preparation of solution
Research: There is no reliable information about clinical trials confirming its efficacy and safety. Often, doctors and pharmacists recommend this tool for children, but use it to treat children should be used with caution or not used at all.
References: Quite a lot of reviews in patients who use Citovir, about the effectiveness and absence of side effects. Improvement of well-being is observed on the second-third day, in single cases the drug did not help.
Price: Cytovir 3 - average240-580rub.
Kagocel
Pharmacological action: inducer of interferon synthesis, antiviral,immunomodulatingeffect. Composition: the sodium salt of the copolymer, which causes the formation of late interferon, which has high antiviral activity. The greatest effect occurs if you start treatment within the first 24 hours of the disease, but not later than the 4th day after the onset of an acute infection. With a view to prevention, it is possible to take it at any time, preferably immediately after contact with a sick Orvy or a flu.
Side effects: the emergence of allergic reactions.
It is issued: It is registered in 2003, since 2005 it is made in tablets, since 2011 it is resolved to use for children over 3 years old for the treatment of influenza, as an prevention for children can be used for children older than 6 years.
Research efficiency and safety: There is conflicting information. The active ingredient is the sodium salt of the gossypol copolymer with carboxymethyl cellulose.
And Gossipol itself is a natural polyphenol, it has been banned in the world since 1998 due to its toxicity. Gossypol for a long time and actively studied by some countries as a contraceptive, with its continued intake completely stops spermatogenesis. Chinese and Brazilian scientists say that host gossypol boys and men may suffer infertility in the future. However, Kagocel is not pure gossypol, it is the sodium salt of the copolymer, which has other properties that differ from the properties of the chemical itself.The manufacturer actively advertises the drug and claims that the salt in Kagocel is negligible, 4 times lower than the concentration from the international standards allowed. Multiple stages of purification of the product ensure the absence of free Gossypol in the final drug, which is checked by monitoring the quality of each series of Kagocel tablets. The method used to check the availability of free gossypol is very accurate, it can reveal its content higher, 036%. In early 2013, data were published on tests performed on rats - no changes in reproductive function were detected in animals.
That is, research on primates was not done? It is known that gossypol for different animal species has its maximum dose of toxicity, according to the EFSA (European Food Safety Authority) for rats the limiting toxic dose is 2200-3300 mg / kg.,for pigs 550, for guinea pigs up to 300 mg / kg. The research carried out by the manufacturer consisted in the administration of therapeutic doses to male rats, and doses 25 times higher than therapeutic doses250 mg / kg). Can you trust the rest of the statements and "studies"?
Neither in Western Europe nor in the United States Kagocel is not used, there are no WHO medicines on the list. The effectiveness of the drug is not proven according to the representatives of the Formulary Committee of the RAMS and SDMX. There were no statistical studies on the development of side effects as of autumn 2013.
The drug is actively recommended for use by adults and children, but evidence of the safety of this medicines for children 3-6 years old no, clinical studies for this age group are not was produced.
Reviews: Many help, some children and adults are allergic reactions in the form of rashes, swelling, itching.
Price: Kagocel - average180-280rub. In 2012, the volume of sales amounted to - 2.64 billion. rubles
Tyloron (Amiksin, Lavomax)
Pharmacological action: active ingredient Tiloron, possesses antiviral andimmunomodulatingaction, it is a synthetic inducer of interferon that stimulates the formation of interferons alpha, beta, gamma.
Side effects: short-term chills, allergic reactions, contraindicated in breastfeeding and pregnancy.
Issued: almost 40 years ago, children under 7 years of age are strictly prohibited.
Research: The benefits of the drug are unquestionable for both treatment and prevention of viral diseases, but this can overlap with potential harm to the body. In the 80's in the US, after tests on mice, the drug was banned, as it had a highly toxic effect,in experimental animals, retinal bundle, liver lipidosis and other side effects were observed. It does not apply in the US and the European Union. In our country, continue to produce antiviral Amiksin and doctors appoint it to patients.
A small study involved 14 patients who received tilorone in a dose of 152 and 189 g, in 2 the drug caused keratopathy and retinopathy (while the visual acuity did not decrease), these effects were reversible. The authors of the study concluded about the potential danger of the drug for health.
Reviews: The occurrence of allergic reactions, the high cost of medicine.
Price: Amiksin - on average500-560rub. Sales volume in 2012 amounted to 7 billion. rub.
Additionally! Medicines, the so-called immunomodulators - Lycopid, Polyoxidonium, Cycloferon, Proteflazide, Timogen, Panavir, Isoprinosine, Neovir, Groprinosin and others. - should not be used to treat children (for various diseases) without immunograms and serious indications as they do not have the proper clinical trials of efficacy and safety in the treatment children.
Antiviral drugs
Below are just some of the antiviral medications from Orvi, reviews about them, a brief description, comments on known studies of their effectiveness, the average price in pharmacies.
Ingavirin
Pharmacological action: active substance imidazolylethanamide pentandioic acid. It is active against adenovirus infection, influenza A, B, respiratory syncytial infection, parainfluenza. It is an immunomodulator that affects the functional activity of the interferon system.
Side effects: allergic reactions
Contraindicated: children under 18 years.
Produced: as a drug for the treatment of influenza and orgi from 2008, before that, according to prof. Vlasova Vasilia Vitaglutam (imidazolylethanamide pentane diacid) was used in Russia before 2008 as a stimulant for hematopoiesis in cancer patients receiving an anticancer therapy.
Research: According to the manufacturers, the idea of producing Ingavirin arose in the 1980s, but Only after many years of research into its safety and efficacy was the drug submitted for registration by 2008 year. When Vitaglutam was used in patients with oncological diseases, there was no convincing evidence of its effectiveness. And when in 2008 Ingavirin appeared on the pharmaceutical market without full-fledged studies, the "epidemic of swine flu" began in the country, therefore Ingavirin was actively sold. The drug was recommended by the Ministry of Health and Social Development, even despite the absence of placebo-controlled studies, reasonable evidence of its effectiveness.
One study conducted at 105!!! of patients with confirmed influenza showed the following results:
- Receiving ingavirin reduced the duration of fever to 3 hours (if used in the first 1 days after the onset of the disease)
- In the placebo group, this is 72 hours
- In the group taking Arbidol - 48 hours
Analyzing the duration and intensity of flu symptoms - weakness, headache, dizziness in patients with ingavirin was confirmed to reduce the severity of the disease, side effects are not revealed.
In May 2009, Alexander Chuchalin, chief therapist of the Russian Federation, (he led a team of drug developers) gave an interview to the magazine Ogonek: "The new antiviral agent Ingavirin efficiency is much higher than that of the AmericanTamiflu. The Russian drug is quickly and easily integrated into the genome of the A / H1N1 virus, immediately destroying it. It is also effective with other dangerous viruses. "
Reviews: Most drug does not help, isolated cases confirm the reduction in the timing of the disease.
Price:380-460rub. From January to June 2010, the sales volume of Ingavirin was 220 million. rubles, 467 thousand packages were sold.
Arbidol
Pharmacological action: Antiviral, has the ability to suppress viruses of influenza A and B, SARS - severe acute respiratory syndrome, associated coronavirus. Arbidol is also used in the complex therapy of acute rotavirus intestinal infections.
Active substance: Methylphenylthiomethyl-dimethylaminomethyl-hydroxybromoindole carboxylic acid ethyl ester.
Side effects: use of children under 3 years is prohibited, individual
allergic reactions.Produced: invented in 1974, in 1992, it began its industrial production.
Research: Until 2013 there was no convincing evidence in its effectiveness and safety. Studies conducted in the USSR have not been published. In Russia in 2008, a study of 300 people showed that Viferon was more effective than Arbidol. In 2004, in China, tests for 230 patients with symptoms of Orvi showed it was not effective, in contrast to Tamiflu and Ingaverin. In 2009, in the journal of the UK "Antiviral Research the authors of the research stated that strains resistant to Arbidol are formed less frequently than those of Remantadine and Amantadine.
The Office of Quality Control of US Medicines denied registration of Arbidol in the United States, and WHO has never considered this drug as an effective antiviral drug.
Update on the drug: At the end of 2013, the World Health Organization Arbidol (umifenovir) as an antiviral drug with a direct effect, assigning it an individual code J05AX13. Thus, Pharmstandard received a nominal permission for widespread use of the drug on the territory of the Russian Federation, where Arbidol is included in the standards of treatment and prevention of influenza and ARVI in children and adults.
Nevertheless, the multicenter test of the effectiveness of Arbidol, which was planned to be completed in 2013, has not been completed to this day, and its terms have been postponed to 2015. The results of this test, which has serious sponsors and does not suffer from a shortage of patients, could put a dot over I in the arbidol epic, but for unknown reasons this is not occurs. I.eevidence of effectiveness is not present until now, it remains to wait ...
Reviews: The same number of positive reviews and opinions about the ineffectiveness of its use. There are isolated cases of allergic reactions in the form of dermatitis, angioedema, pain in the epigastric region.
Price: Arbidol - on average130-710rub. In 2012, the volume of sales - more than 5 billion. rub.
Tamiflu
Pharmacological action: an antiviral drug, which includes oseltamivir carboxylate (active metabolite), suppresses influenza A and B viruses. When Orvi is not effective.
Side effects: Nausea, insomnia, diarrhea, dizziness, lethargy, cough, headaches, with caution to pregnant women and lactation. Contraindicated for children under 1 year.
Produced: since 1996, the pharmaceutical company "F. Hoffmann-La Roche "registered the right to develop
preparations containing oseltamivir.Research: Tamiflu has a disadvantage - it complicates the diagnosis, because side effects are similar to the symptoms of influenza. It is dangerous in the epidemic period with long-term admission. Optimum effective only short-term use - a few days at the beginning of the flu. Independent researchers demanded a standard report from the Swiss manufacturer of 4-5 research modules. To which the pharmaceutical company provided only the first modules, repeated requests for full information were never satisfied.
Since 2004, cases of neuropsychic disorders began to be registered, more often in children and adolescents, who took Tamiflu during influenza - hallucinations, nightmares, confusion, convulsions, anxiety, etc.
Japanese postmarketing studies of this drug in 2006 have indicated a risk of developing impaired consciousness in humans - psychosis, depression, suicidal tendencies, especially in children. And there were also 54 deaths after Tamiflu, 16 of which were in adolescents 10-19 years (15 killed suicide, 1 died, hitting a car), the rest died of kidney failure (it is possible that due to severe flu).
The latest information about this drug:Back in April 2014, the Cochrane Society (an independent health research network) represented by Tom Jefferson and the British Medical the journal published data from the Cochrane review of studies that did not confirm the efficacy of Tamiflu and Relenza in the treatment and prevention influenza. Also, the efficacy of reducing influenza complications with these drugs has also been questioned. The firm attempts of Roche firm to fight back with a firm promise to provide undeniable evidence in the form of results of randomized trials have so far not been successful. Evidence is expected to present.
April 10, 2014, the Cochrane Collaboration website published the results of these 26 clinical trials Relenza and 20 clinical trials of Tamiflu, in which 2, 00 people participated.
As a result of the research it was found that:
- Oseltamivir as a preventive agent slightly reduces the risk of developing influenza in families, without reducing the ability of the influenza virus to be transmitted from person to person.
- The duration of symptoms is reduced by 16 hours (from 7 to, days), in children this effect is absent altogether.
- The drug has no effect on the risk of serious complications (sinusitis, otitis media, pneumonia, bronchitis), that is, does not reduce the likelihood of complications.
- The medicine is recognized as sufficiently toxic, increasing the risk of nausea, vomiting in both children and adults.
- When used for preventive purposes, the drug was dangerous to health, because it leads to mental disorders, impaired renal function, in some cases found that it helps to reduce the production of their own antibodies to the virus.
Based on these studies, health officials of the world's leading countries should decide to stop mass procurement of antiviral drugs with the current substance Oseltamivir due to the high risk of side effects and low effectiveness as a medicine for the therapy and prevention of influenza virus in the period epidemic.
reference: only on the basis of the claims of the manufacturer Tamiflu that the drug significantly reduces the risk of serious complications and hospitalization of patients during the epidemic, countries such as the United Kingdom and the United States in 2009 in connection with the epidemic of swine flu, these drugs were purchased at 40 million doses (The USA, bln. dollars, Great Britain 424 million. f.St.).
Based on recent data on the low efficacy and non-safety of this antiviral agent, an international group experts in evidence-based medicine called on the governments of the world's leading countries to stop mass purchases of Tamiflu and Relenza.
Reviews: There are enough reviews about side effects in the form of vomiting, dizziness, psychosis, headache. The effectiveness of influenza is confirmed by many.
Price: Tamiflu-on average1200-1300rub.
Remantadine (Rimantadine)
Pharmacological action: antiviral drug, an adamantane derivative, suppresses various strains of the influenza A virus (swine flu including).
Side effects: contraindicated in pregnant women, children under 1 year. Reduces concentration of attention, causes dizziness, nervousness, headache, increased fatigue, nausea, vomiting, dryness in
mouth.Produced: information on the first uses of the drug are known since 1968.
Research: The tests were conducted from 1981 to 2006, mainly they showed a lower toxicity of Remantadine in comparison with Amantadine. One study showed the effectiveness of preventing Amantadine influenza infection by 61% in compared with the placebo group and in the event that a person fell ill, then for 1 day reduced febrile syndrome. In the same study, he was compared to Tamiflu, he gave an efficacy of 73% of the placebo group. Rimantadine (Remantadine) is currently considered a drug with proven clinical efficacy, but the possible resistance to it of some strains of the influenza virus.
Reviews: There are reviews that Remantadin causes side effects - dizziness, tachycardia, bitterness in the mouth. In general, the reviews are positive.
Price: Remantadine - average50-150rub.
It is during the flu (including swine) with the first symptoms of therapists and pediatricians recommend: adults - Remantadin, Tamiflu. Children over 1 year old are shown by Orvir (rimantadine syrup), Viferon. Children older than 8 years can - Remantadin (in the table), Tamiflu.
Interferon preparations
Interferons are informant proteins, which are excreted by cells infected with viruses. They seem to inform other cells about the infection and the required inactivation of the virus. Alpha interferons produce lymphocytes, beta - fibroblasts. In addition to Viferon, the alpha group includes Intron, Reaferon, Kipferon.
Viferon
The creation of the drug was scientifically justified in the period 1990-1995. group of scientists of the Research Institute of Epidemiology and Microbiology. N.F. Gamaleia under the guidance of prof. Malinovskaya V.V.Since December 1996 on the basis of the same SRI, serial production of recombinant interferon alfa-2b in suppositories begins. Viferon - a candle with a different content of the active substance.
Application:
- Viferon-1 (150000 IU) is designed for babies from birth to 7 years. It is used in ARVI, herpetic infection, as an additional remedy for prolonged pneumonia or sepsis, including in preterm infants with intrauterine infections. The drug is given a course for 5 days. Children under 7 years are recommended 1 candle 2 times a day. Preterm, born on a period of more than 34 weeks - as children under 7 years. With a shorter gestation period - 1 candle three times a day. If necessary, after a five-day break, the course can be repeated for another 5 days.
- In children older than seven years, an adult drug in candles for 50, 00 IU is used twice a day for five days. Possible use of viferon in pregnant women.
- Candles with viferon content of , 0, 00 and , 0, 00 IU are used in the treatment of viral hepatitis and herpetic infections.
- The preparation in the form of ointment is intended for the therapy of herpes on the skin and mucous membranes in adults and children older than a year.
Side effects: the main side effect of drugs viferon may be an allergic reaction, which happens infrequently.
Research: As for the effectiveness of the drug, it is not included in list A of evidence-based pharmacology. I.e,wide randomized trials in humans consistent with international standards were not performed. However, a positive practical experience of treatment with viferon in pediatric practice is available. (By the way, nitroglycerin also does not have randomized studies that prove its effectiveness, which does not make it an ineffective first-line drug for stenocardia). Publications of these clinical trials of the drug are available only in Russian and were conducted only in domestic clinics. Value for money allows pediatricians to recommend a drug for ARVI treatment in children younger than seven years. For adults in the treatment of acute respiratory viral infections, the drug is of limited use because of rectal administration and the availability of alternative drugs.
The main arguments of the opponents of the drug:
- high molecular weight of protein molecules that can not be absorbed in the gut
- lack of clinical trials that meet international standards.
Kipferon
In candle light a little expensive for the treatment of common colds. Therefore, it is replaced by viferon. But, with severe forms of intestinal dysbiosis in children of the first two years of life, the drug shows good clinical results.Studies: Randomized trials were not conducted, that is, the drugrefers to the list of drugs with unproven effects. The main claims:
- High molecular weight, which prevents normal absorption
- Adding to the drug components of the donor blood, which can cause fever and allergies.
Cycloferon
Cycloferon was originally registered as a veterinary drug in 1993 for the treatment of animals with viral infections, in 1995 it was already honey. a drug.
The drug Cycloferon is approved for use in adults and children older than four years. Produced in solution for injection, tablets, liniment. Refers to immunomodulating drugs, is an inducer of interferon, enhancing its production and exhibiting antiviral, anti-inflammatory and immunostimulating properties.
Application: on the territory of the Russian Federation is used in the treatment of acute respiratory viral infections, influenza, viral hepatitis, herpes infection, human papillomaviruses and other urological and gynecological pathologies (eg, candidiasis, chlamydia).
Contraindications: The drug is not recommended for pregnant and lactating. May cause an allergic reaction.
Research: Cycloferon is an immunostimulant that stimulates the immune system and the production of interferons. To date, allclinical trialsthis drug, published in the medical literature,were conducted only in the territory of the Russian Federation and do not meet international standards.
There are no serious clinical trials for cycloferon that would prove its effectiveness or refuted the absence of long-term adverse effects of this drug (development of autoimmune diseases). It is not superfluous to recall that all drugs that are on the pharma market for less than five years are still at the fifth level pharmacological tests and it is quite possible to identify previously unknown undesirable effects from drugs such series. In the presence of newly identified harmful effects, the drug will be withdrawn from the pharmacy networks and discontinued, and most of those who have been treated with this remedy and have earned some disruptions in health are unlikely to receive at least some compensation.
Conclusions:
Ineffectiveness of antiviral agents due to the stability of strains of the virus
The lack of a positive effect with the use of certain antiviral drugs for influenza is possible, and because there are drug-resistant viruses and a specific influenza strain may already be resistant to a particular drug (eg, Remantadin).
Other treatments and placebo effect
It is also possible that patients whose reviews indicate the efficacy of such remedies were quickly recovered by other methods of symptomatic treatment, and the placebo effect is not excluded (cf. amazing facts about placebo).
Strong immunity
In a healthy organism, after 2-3 days, the immune system produces enough protective antibodies against the virus, it does not need additional medicines. It is enough to comply with all the known rules - bed rest, plentiful hot drink, vitaminized foods and drinks, clean air in the patient's room, gargling, etc.
Rapid recovery with antiviral drugs
In various life situations, reducing the duration of the disease even for one day can be very important, for example - wedding day, urgent business trip, important business deal, exam, interview and etc. It is in such cases that the use of antiviral drugs, which reduce the duration of the illness by 2-3 days, may make sense.
There are no adequate studies
Absence of benign studies on the study of effectiveness and side effects (on a large group of people, different ages, during long time), most antiviral agents from Orvi and influenza suggest the caution of their use or even the rejection of them.
Do not spend money on pacifiers
Spending money, in some cases, considerable, on drugs with unproved efficacy, side effects, questionable safety, perhaps, is not advisable. Any medicine, even useless or empty, can damage the body.
Video transmission: How the placebo effect works
- sec: 4 min. - about what means are usually prescribed by doctors
- with 2: 0 - about the effect of placebo on the work of the immune system
- with 3: 7 - about the high effect of placebo in children
- with 3: 5 - about preparations-pustachki, appointed or nominated at ORVI
- with 3: 0 - about homeopathy and antiviral drugs in ARVI
- with 4: 7 - on how modern research is conducted
zdravotvet.ru
Effective drugs for ARVI and influenza
At the time of worsening epidemiological situation, the question of how to effectively treat ARVI and influenza is very acute; drugs that modern pharmacological industry, help not only to eliminate the symptoms of viral diseases, but also to influence the mechanisms of their development, which makes them the main means of treatment virus infections.
Influenza is a part of the ARVI group, so this type of illness is similar in its symptoms. The difference is the duration of the incubation period, the course of the disease and the complications of advanced forms of the disease. The similarity of the symptoms makes it possible to apply an identical remedy for cold and flu for therapeutic therapy.
Features of viral infections
To select the effective treatment of viral respiratory diseases, the doctor focuses on such symptoms as:
- fever, chills;
- pain in the muscles;
- headache;
- general malaise, weakness;
- high body temperature;
- change in the condition of the lymph nodes;
- inflammatory processes in the airways.
In some cases, there may be swelling of the larynx mucosa, coughing and lacrimation. Influenza begins suddenly and has more severe symptoms than SARS or ARI. With a typical manifestation of these types of viral infection and their course for more than 7 days, the doctor prescribes effective medications for cold and flu. Especially it concerns small children, if begun ORVI is complicated by additional symptoms from other organs. Of great importance in this case is antiviral therapy, which consists of three main areas:
- influence on the cause of the disease and directly on the virus-causative agent with the help of etiotropic drugs;
- influence on the mechanisms of the development of the disease;
- elimination of painful symptoms.
When new symptoms appear in the form of a cough, runny nose, fever, only the use of antiviral medicines helps. During this period, active propagation of the virus-agent occurs, therefore, as soon as the patient began to observe these symptoms of a cold, these medications must be taken immediately. After a few days, taking these medicines will be useless.
Classification of antiviral agents
Drugs from influenza and colds are divided into several groups:
- interferons and their inducers;
- antiviral antibiotics;
- antiviral phytopreparations;
- stimulants of immunity - immunomodulators.
Due to their effectiveness, the multiplication of viruses in cells ceases, which allows us to further protect the body from a virus attack.Interferon is a powder that is dissolved in boiled water.
It is taken immediately before contact with the infected person and before leaving for places with a large population of people. Use the drug as follows: dissolved powder is injected into each nasal canal for 5 drops for 2 times a day.
For today it is the best remedy for viral diseases. The earlier his reception is begun, the more effective he will show himself. When the infection begins, the dosage of the drug is changed. The drug is administered 5 drops every 2 hours (5 times a day).
Treatment continues for three days. You can treat the disease with Interferon, using it as a substance for inhalation: in 10 ml of warm water dilute 3 ampoules. The thermal procedure is carried out 2 times a day for 3 days.
To this group of drugs is another means for influenza and viral infections - Grippferon, which is a combined preparation of preventive and curative action. The drug is instilled in the nasal passages every 4 hours for 3 drops. If the patient is sensitive to the components of the drug, its use is discontinued. It is contraindicated for pregnant women, especially in the early stages.ARI and influenza are treated with Viferon. Recently, doctors recommend it for treatment of young children as the best tool to help stimulate the formation of interferons in the body. They have a depressing effect on different groups of viruses such drugs from influenza and ARVI, as Amiksin, Lavomax, where the active substance is Tyloron.
Arpeflus, Arbidol, Immustat - a group of drugs that help increase the body's resistance to viral infections. The main substance in them is Umifenovir.
Other antiviral agents
Treatment for colds and influenza is also carried out with the help of other drugs that inhibit the process of reproduction of the virus by affecting its shell. These medications include Remavir, Rimantadine.
For children this type of medicine is prescribed for treatment and prevention. Packaged powders are diluted in water and given in the scheme. As a preventive tool, it is recommended to drink the medicine for two weeks with 1 diluted bag (the dosage varies according to the age of the child).All these groups of drugs have side effects and contraindications. To avoid severe consequences, it is necessary to carry out a sensitivity test and strictly observe the dosages for the treatment prescribed by the doctor. The most common side effects are nausea, dizziness, stools, hypertension, allergies. Especially cautiously should take these drugs to people with kidney disease.
Other types of drugs that act solely on the influenza virus are neuraminidase inhibitors. These include Zanamivir, Relenza. These drugs are used only as inhalants as a curative and preventive agent. Preparations in which the active substance is Zanamivir, have a high degree of toxicity, which demonstrates a large number of side effects. Very carefully it should be taken to people with kidney diseases and prone to allergic reactions.
Preparations of the natural group
Inhibiting the activity of influenza virus neuraminidase and helping the body to produce its own interferon are antiviral drugs of plant origin.Effective among them are Proteflazide, Flavozid, Altabor, Immunoflazid, in which the extract is an active alder. This type of medicines has not only antiviral, but also antibacterial action. For medicinal and prophylactic purposes, the medicine is taken three times a day, dissolving two tablets. The course of treatment is 7 days.
If a patient has increased sensitivity to this group of drugs, the doctor appoints others. Against the background of long-term use of drugs in this group, there may be an allergic reaction. When pregnancy and breast-feeding, they are also not recommended.
To reduce and stop the multiplication of viruses, the administration of Proteflazide, Flavozide, Immunoflazide, which are made on the basis of medicinal herbs of pike and turtle, terrestrial.
This group of medicines is also characteristic of its immunomodulating feature. Doctors appoint them as a curative and preventive agent. Immunoflazid - syrup, which is used for two weeks twice a day for 9 ml. With a preventive purpose, it is consumed within a month.The drug Flavozid is taken according to the scheme: 5 ml twice a day from the first to the third day of the disease, starting with the fourth - 8 ml. Preparations made on the basis of phytocomponents almost never show side effects. Their reception is contraindicated only to pregnant women in the first trimester, as well as during lactation.
Complex homeopathic antiviral drugs that suppress the active action of viruses are Engystol, Sagrippin, Amizon, which have antipyretic, anti-inflammatory, interferonogenic properties.
Treatment of children
In acute respiratory viral diseases, pediatricians recommend the use of homeopathic medicines - candles, powders, syrups. These types of drugs actively suppress viral attacks and increase the protective properties of the child's body. These include Viburkol and Aflubin, Gripp-Heel, EDAS-903 and others. Significant effectiveness of these drugs with simple forms of viral diseases.
Some pediatricians are inclined to believe that not all phyto-drugs have an effective antiviral effect, so they advise not to experiment with the health of the child. If the drug does not begin to show therapeutic effect within 24 hours, it should be replaced with a drug of another group.Treatment of influenza and colds in children is carried out with drugs such as Arbidol, Rimantadine, Ribavirin, Tamiflu. In some cases, it is recommended to take Acyclovir, which acts on many types of viruses. Rimantadine, as a rule, is used only to neutralize the influenza virus, it does not have the proper effect on other types of viruses.
This drug is considered the most in demand during the flu epidemic as a preventive. It is shown in the treatment of children and Ribavirin, which in its spectrum of action is very similar to Rimantadine. In addition, it has a depressing effect on the virus that causes pneumonia in infants. If there is a decrease in the effectiveness of rimantadine, it is advised to replace it with Ribavirin.
The spread of the virus in the child's body delays Arbidol. Despite its popularity in ARVI, it can only have a curative effect on influenza viruses. Of all antiviral drugs for children, Tamiflu is recognized as the most effective.
.Its activity is observed not only in the early stages of the disease, but also in the period of exacerbation. Its effect is several times stronger than other drugs. Tamiflu has side effects, so it is prescribed only to children who are 12 years old.
Assign drugs and interferon group with a child's dosage - suppositories Viferon, drops Grippferon, suppositories Kipferon. The drug of the new domestic pharmacy Derinat, despite its recent existence on the pharmacological market, has won many positive reviews.
It is available in the form of drops. This helps start an active fight against the viruses through the nasopharynx, preventing them from penetrating further into the body. The drug helps to strengthen the effect of drugs that treat a child in conjunction with Derinatom. It is allowed to use this medicine for infants from the first days of life.
.Sometimes children are prescribed immunostimulating agents - Riboxin, IRS 19, Imudon, Bronhomunal, Metiluracil. There are separate types of these medicines, prescribed by the pediatrician as a prophylactic, and those that are can appoint only immunology doctors after a special diagnosis of the immune characteristics of the body child. It must be remembered that immunostimulants do not have a therapeutic effect during the active development of the disease. They are used before the infection begins to multiply in the body.
respiratoria.ru
Information: Effective antiviral drugs against influenza
Antiviral drugs against influenza help the body to conquer the disease faster by increasing the synthesis of interferon. Experts advise taking antiviral medications for influenza, because this way you can kill the pathogen of the problem faster and save the person from possible complications.
Why you need to use antiviral drugs
If the human body is completely healthy, then to fight the flu or cold it can and without additional help. In the event that the immunity of a person is strong, the disease will proceed in a fairly easy form. Otherwise, it is necessary to use antiviral drugs, because a weak immune system can lead to serious complications after the flu.
With the help of an antiviral agent, the healing process can be accelerated and the duration of the disease reduced to 3 or 5 days. At the same time the risk of serious enough complications decreases several times. It is worth noting that drugs of this type will be effective only at an early stage of the disease. Take the money you need to start immediately after you notice the first signs of the flu, because later they will not bring any positive result.
Medications that are based on interferon
Interferons are special proteins that begin to produce every cell of the human body when a virus enters it. Thanks to this substance, it is possible to stop the development of pathogenic flora without problems, and then the person is not sick. Sometimes the body can not independently develop the right amount of this substance, so when influenza should take antiviral drugs, which are based on a sufficient number of interferon.Most often, experts are appointed to treat influenza:
- Cycloferon.
- Kipferon.
- Viferon.
Cycloferon is one of the inducers of interferon, which has an antiviral and immunomodulating effect on the body of a sick person. This drug is often used not only against the flu, but also for the treatment of colds or ARVI. The medicine is given in tablets, and you can take them after 4 years. The essence of the work of cycloferon is very simple: it affects the induction of alpha and beta interferons, which makes the cells of the human body immune to the causative agent of the flu.
Kipferon also kills viruses and improves the functioning of the immune system. Thanks to the effect of this drug, you can quickly and easily eliminate the inflammatory processes that occur during the flu. Kipferon is sold only in the form of candles and it is often used to treat influenza, acute respiratory infections, colds, intestinal, adenoviral infections. Kipferon allows several times to increase the immune defense of the body, due to its effect on the induction of interferon. Accordingly, the development of viruses stops, and then they die.Viferon - a drug is one of the complex antiviral drugs that treat the flu, colds, herpetic or hepatitis infections. You can buy Viferon in the form of candles, a gel or an ointment. The effect of the remedy is that it suppresses the influence of viruses and at the same time activates the human immune system. Use these drugs for influenza can not only adults, but children.
Antiviral drugs of direct effect
Drugs of this type act directly on the virus, which provokes the development of influenza. As a result, the viral envelope does not merge in the cells of the human body. At the same time, direct-acting drugs provoke additional production of interferon in the human body.
Most often for treatment use such drugs of direct effect:- Ingavirin.
- Rimantadine.
- Arbidol.
- Tamiflu.
Ingavirin is a modern antiviral agent that contains vitaglutam in its composition.The medicine allows to cure the influenza A and B, kills adenoviral infections.At the same time, this medicine stimulates the functioning of the immune system and stops the development of inflammatory processes. As a rule, Ingavarin is prescribed in the presence of influenza, acute respiratory infections, parainfluenza. Do not take the drug before age 18, pregnant women, during lactation or if there is an increased sensitivity to individual components of the drug.
Rimantadine is used not only for treatment, but also for drug prevention. As a rule, they only treat influenza A group. Can not be used during pregnancy or to treat children under 7 years old. Contraindicated taking rimantadine in the event that there are any specific problems with the kidney or liver.
Tamiflu is a modern drug that appeared on the shelves of the pharmacy just recently. Used to treat influenza A and B. At the same time, tamiflu will not bring any effect if it is used to treat a cold, SARS. Due to the fact that the medicine has an incredibly high level of toxicity, it is not used as a preventive measure. Do not use the drug for a long time, because it can provoke problems in the work of the kidneys or cause a mental disorder.
.Immunostimulating agents for influenza
Such drugs are aimed at quickly and safely strengthen the immunity of a person who has the flu:
- Tyloron.
- Kagocel.
- Cytovir 3.
Tyloron is a synthetically derived interferon inducer. Tablets of the drug are very effective during treatment of influenza, colds, SARS, viral encephalomyelitis. Even considering the toxicity of Tyloron, it is still used as a preventive measure. At the same time, drugs can not be used to treat children under 7 years old, pregnant women, while breastfeeding.
Kagocel was invented relatively recently, and it very well stimulates additional production of interferon. A remedy effective for treating all strains of flu, cold or SARS. In order to obtain the desired result of treatment, it is necessary to take the drug as early as the first day after the disease manifested itself. Do not use Kagocel tablets to treat pregnant women or children who are under 3 years old.Cytovir 3 has a complex effect on the human body, it is actively used for rapid production of interferon in cells. They are used to treat acute respiratory viral infections and influenza at the initial stage of the disease. At the same time, it is not possible to use as effective an agent as Cytovir 3, in the form of a syrup for treating children under 1 year, in the form of capsules - up to 6 years. Contraindicated drug pregnant women and during lactation.
Means against plant-based viruses
This plant increases the natural production of interferon, the activity of influenza viruses very quickly begins to be suppressed.
To date, experts have proven that some medicinal herbs can destroy viruses. On their basis, and were created drugs that are intended for the treatment of influenza, SARS, colds and while they are completely safe and do not harm the body of a sick person. At the same time, it is very important to monitor the condition of the body, so that in case of an allergic reaction, stop treatment with such medicines in time.The most commonly used for the treatment of influenza are the following herbal antiviral agents:
- Altabor.
- Immunoflavid.
- Proteflazide.
- Flavozid.
The albator in its composition contains a large number of ancestral alder.
At the same time, Albator is able to kill many other bacteria. You can not use this medication during pregnancy or lactation. In addition, scientists have no information about the influence of Albator on the children's body.
The rest of the medicines have almost the same composition, and they are based on extracts of such herbs as pike and turkey grass. With the help of these drugs you can oppress the enzymes that produce viruses. Accordingly, the viruses stop multiplying and soon die.
.Flu is a serious disease that needs to be treated with antiviral agents. It is not necessary to engage in self-treatment and it will be better to contact a specialist, he will help to select the right medicine as accurately as possible, which would not harm your weakened organism.
respiratoria.ru
Effective antiviral drugs for influenza and ARVI
p & g; antiviral drugs are medicines today, about the appropriateness, effectiveness and safety of which are many disputes among specialists. This group of drugs has been used relatively recently, is actively advertised and is often prescribed by therapists for signs of influenza and ARVI. Consider which of these tools can be considered the most effective.What antiviral drugs are most effective in ARVI?
To the causative agents of acute respiratory diseases, which are the most common infectious diseases, there are more than two hundred types of viruses. Drugs that act directly on these respiratory pathogens, like antibiotics when there are no bacterial infections in our pharmaceutical market (with the exception of preparations against viruses influenza).
But there are a number of drugs that contribute to increasing the body's defenses, increase its resistance to the oppressive effects of viruses that create barriers to their spread. Their use, according to manufacturers, can achieve a speedy recovery, reduce the intensity of unpleasant co-occurring symptoms, reduce the risk of complications.
These drugs include:
- interferons;
- inducers of interferon;
- means of plant origin.
It should be noted that almost all such drugs do not have proven effectiveness and have a lot of side effects. In addition, some experts believe that artificial stimulation of immunity can be dangerous and have long-term adverse effects in the form of development of autoimmune and even oncological diseases.
Despite this, many patients note that the antiviral drugs they take really work and allow you to cope faster with the disease. Here are some names of antiviral drugs for ARVI treatment, about which there is the greatest number of positive reviews:
- Immunal;
- extract of echinacea;
- Amiksin;
- Viferon;
- Gripferon;
- Polyoxidonium.
It should be understood that only a doctor should prescribe this or that drug, taking into account the individual characteristics of the human body, the available accompanying pathologies. Independent and uncontrolled use of antiviral drugs in ARVI can cause significant harm.
What antiviral drug is the most effective for influenza?
At the moment, the main drugs for the treatment of influenza types A and B, the use of which is effective, are:
- Relenza (zanamivir);
- Tamiflu (oseltamivir).
The action of these medicines is based on the ability to block the propagation of pathogens in the body, thereby increasing the chances of a speedy recovery without the development of complications. An important condition for the effectiveness of the use of these funds
is the timely beginning of their application - no later than 48 after the onset of symptoms of the disease. Otherwise, their reception is practically useless. Unfortunately, the drugs in question are not devoid of many side effects and in some cases can be contraindicated for use even with very severe flu.In conclusion, once again, the use of any, the most effective antiviral drugs in the treatment of influenza and SARS should be agreed with the attending physician and conducted under his supervision. And in order not to lower the development of diseases, it is recommended to apply preventive measures, temper the body and adhere to a rational diet.
WomanAdvice.ru
Antiviral drugs for colds
Antiviral drugs for colds - the main tool in the fight against this category of ailments.
As is known, during the period of activation of catarrhal diseases it is better to be engaged in their prevention, and not to bring them to conditions when treatment is already needed. Activating immunity in the cold season is the most effective measure to protect yourself against colds. Then the disease will not develop or, at least, the situation will not take on a serious form.
If the disease has a viral nature - acute respiratory viral disease (ARVI) - then there can not be no treatment without treatment. And it is best in this case to cope with the problem of antiviral drugs. The essence of their action is in the impact on the virus itself, which is an etiological factor.
Antiviral drugs are used to treat ARVI and influenza. These drugs affect the replication of the virus in such a way as to stop its reproduction. Antiviral drugs are synthetic or natural. They are used both in the fight against the disease, and for its prevention. Different stages of the common cold can be exposed to antiviral drugs. To date, modern science knows about five hundred pathogens of different kinds of colds. Antiviral drugs to fight them quite a bit.
In general, viral diseases are treated with three types of drugs:
- drugs for a wide spectrum of influenza;
- drugs for the treatment of herpes infections.
- means for controlling cytomegalovirus.
In the case of severe disease, antiviral drugs are taken, with the use of interferons is easy. Within a day and a half after the appearance of the first symptoms, it is urgent to begin taking an antiviral drug. If we allow the multiplication of the virus to such a scale that it will occupy the entire body, then it can be brought to the conclusion that taking medications will not have any effect.
Effects of antiviral drugs for colds
With the help of antiviral drugs, the causes of the onset and development of acute respiratory disease are eliminated. The results of this action are:
- reduction of risks of exacerbations of chronic diseases (chronic bronchitis, bronchial asthma, etc.);
- shortening the course of the cold for several days, alleviating its symptoms;
- a reduction in the risk that severe complications will appear after acute respiratory illness.
Antiviral drugs for colds are also used as an emergency prophylaxis in the event that one of the family members becomes ill and needs to reduce the risk of infection of healthy people.
Antiviral tablets for colds
In a class where there are synthetic antiviral drugs that cope well with the influenza virus, there are two groups of effective remedies. The essence of the action of M-channel blockers in the blocking of the virus so that it can not penetrate into cells and multiply. One of the tested preparations against viruses of this category is Amantadine (Midantan), and also Rimantadine (Remantadin). For the desired effect, they should be taken as soon as the disease begins to manifest itself. Another of their drawbacks is that it is not always possible to understand what kind of virus a person has become. And these antiviral drugs are shown in the epidemic from the influenza A virus. In addition, avian and swine flu are resistant to them. It is important to remember that taking an antiviral drug for a cold should be done not only by the sick person himself, but by all members of his family.
Effective antiviral agent for colds
But neuraminidase inhibitors act on influenza A and B viruses. The essence of their action in suppressing the enzyme, which is responsible for the multiplication of the virus. Representatives of this group of drugs are "Oseltamivir" ("Tamiflu") and "Zanamivir" (Relenza). You can start taking them within two days from the initial manifestations of the disease.
List of antiviral drugs for colds
- Tamiflu;
- "Relenza
- "Grippferon
- Anaferon;
- "Amiksin
- Kagocel;
- Remantadin;
- "Viferon
- Arbidol;
- "Ribavirin
- "Amizon
- "Cycloferon."
Antiviral drug for cold "Zanamivir"
"Zanamivir" is prescribed for influenza in adults and children over 5 years of age for 5 mg of inhalation twice a day for 5 days. The total daily dose reaches 10 mg. The drug is not combined with other inhaled medications (including bronchodilators), because of that exacerbations are possible in patients with bronchial asthma and other nonspecific diseases lungs. In a number of people without pulmonary pathology, there may be signs of nasopharyngeal irritation, reaching in rare cases before the appearance of bronchospasm.
Antiviral drug for cold "Oseltamivir"
For influenza for adults and children over 12 years, the recommended dose of "Oseltamivir" is 75 mg 2 times a day for at least 5 days. "Oseltamivir" is prescribed for children older than 1 year - with a body weight of less than 15 kg of 30 mg, 15 to 23 kg of 45 mg, 23 to 40 kg of 60 mg, more than 40 kg - 75 mg twice daily for five days.
The drug is administered with caution in renal failure, it can cause nausea and vomiting during admission.
Antiviral drugs for a cold of a wider spectrum of action - "Ribavirin" ("Ribarin") and "Inosin Pranobeks" ("Grosprinozin").
Antiviral drug for cold "Ribavirin"
"Ribavirin" acts on influenza A and B-viruses, parainfluenza, respiratory syncytial virus, coronaviruses, rhinoviruses. The specificity of the drug is its high toxicity, therefore it is used only if a respiratory syncytial infection is confirmed that often leads to bronchiolitis in children.
"Ribavirin" is used to treat influenza in adults over 18 years (200 mg 3-4 times a day in meal time for 5-7 days) in the absence of pregnancy, kidney failure and hemolytic anemia.
Antiviral drug for cold "Inosin pranobeks"
"Inosin pranobeks" fights against viruses of influenza, parainfluenza, rhinoviruses, adenoviruses. This antiviral drug for cold stimulates the defenses of the human body. To treat influenza and other acute respiratory viral infections it is recommended to take: adults 2 tablets 3-4 once a day at regular intervals for 5-7 days; children a daily dose of 50 mg per kilogram of weight body.
The daily dose should be taken at 3-4 times at regular intervals. The duration of treatment is 5-7 days.
Interferons and interferon inducers
Another large group of antiviral drugs for colds are interferons and interferon inducers. Interferons are protein substances that synthesize the body as a response to infection, due to them the body is more resistant to viruses. They have a wide spectrum of action, which favorably differ from many other synthetic drugs. But some experts say that they are not very effective in ARVI. In the case of colds, they are prescribed as drops in the nose and rectal suppositories. The native leukocyte interferon is digested four or six times a day, Reaferon (interferon alfa-2a) two drops twice-four times a day. Viferon (alpha-2b interferon) usually goes like a candle, adults usually use Viferon 3 and 4.
There are also inducers of interferon. These are drugs that stimulate the body to produce its own interferons. Catarrhal diseases are treated with "Tyloron" ("Amiksin"), "Meglumina acridonacetate" ("Cycloferon") and a number of other antiviral drugs for colds.
Antiviral drug for cold "Amiksin"
For treatment of influenza and acute respiratory disease, "Amiksin" is prescribed inside after eating two tablets, 25 g for adults and 6 g for children over 7 years on the first day of illness and then 1 tablet every other day.
The course of treatment - up to 6 tablets. Contraindicated in pregnant women and children younger than 7 years.
Antiviral drug for cold "Cycloferon"
"Cycloferon" is used to treat influenza and ARI in the form of intramuscular injections at a dose of 250 mg (1% 2 ml) for two consecutive days, then every other day or 1 tablet, 5 g every other day for 20 days.
Antiviral drug for cold "Kagocel"
"Kagocel" is an inducer of interferon with direct antiviral and immunomodulating action.
Usually it is prescribed for influenza and ARI adults 2 tablets 3 times a day for the first two days (daily dose is 72 mg), then 1 tablet 3 times a day (daily dose of 36 mg). A total of 18 tablets per 4-day course.
Antiviral drug for cold "Arbidol"
Effective in treating the common cold is an antiviral drug, like Arbidol. It acts against viruses A, B, it also treats parainfluenza, syncytial infections, adenoviruses. The essence of the drug in stimulating the production of endogenous interferon, it has an antioxidant effect, strengthens the immune system.
Arbidol for colds without complications appoint: children from 3 to 6 years - 50 mg, from 6 to 12 years - 100 mg, over 12 years and adults - 200 mg 4 times a day (every 6 hours) for 5 days. With the development of complications (bronchitis, pneumonia, etc.) children from 3 to 6 years take Arbidol 50 mg each, from 6 to 12 years - 100 mg, over 12 years, adults - 200 mg 4 times a day (every 6 hours) for 5 days, then a single dose once a week for month.
Antiviral drug for cold "Amizon"
Antiviral drug for cold "Amizon" is an inducer of endogenous interferon, has antiviral, immunomodulating and anti-inflammatory action.
Adults take "Amizon" 2-4 times a day after a meal with an average flow of influenza and acute respiratory disease, 5 g, with a heavy - on, g for 5-7 days; the course dose of treatment is 3 Children aged 6-12 years drink on, 25 g 2-3 times a day for 5-7 days.
Antiviral drug for cold "Anaferon"
"Anaferon" refers to homeopathic remedies with antiviral and immunomodulating effect. It is also used to treat colds and flu. Usage for adults: 1 tablet, sublingually from three times a day to six, depending on the severity of the disease.
Treatment begins with the first respiratory symptoms. After improving the condition, it is recommended to switch to taking the drug once a day, for 8-10 days. Children from six months to three years, one tablet dissolved in 15 ml of water and give a drink. For prevention, Anaferon is prescribed one tablet once a day, for one to three months.
Antiviral drug for colds "Grippferon"
"Grippferon" is an immunomodulatory, antiviral and anti-inflammatory drug for intranasal use. The duration of the course of application and dose of the drug "Grippferon" is usually determined by the doctor in charge.
The recommended dose for children younger than 1 year is 500 IU (1 drop of the drug) 5 times a day; for children from 1 year to 3 years is 1000 IU (2 drops of "Grippferon") 3-4 times a day; from 3 to 14 years is 1000 IU (2 drops of the drug "Grippferon") 4-5 times in a day. The recommended adult dose is 1500 IU (3 drops) 5-6 times a day. The course duration is 5 days.
Herbal antiviral drugs for colds
Some herbs also have an antiviral effect. The effect of many herbal medicines is directed against viruses belonging to the herpes family. Catarrhal diseases are often accompanied by herpes rash, in addition, the course of cytomegalovirus infection also often occurs with the same symptoms as ARVI. This category of drugs includes "Alpizarin". The active substance in it is an extract of such plants as an alpine penny, a yellow penny, mango leaves. The antiviral preparation "Flacoside" has in its composition an active substance, which is obtained from velvet Amur and velvet Laval. For external use, the ointments "Megozin" (cottonseed oil), "Helepin" (ground part of the cheesecake), "Gossipol" (are obtained when processing the cotton seeds or the roots of cotton).
Antiviral drugs that are used for colds also include Altabor. It is based on an extract of stems of gray and black (sticky) alder.
The pendulous shank and ground reed give life to the drug "Proteflazidu it is also used in the treatment of colds, influenza and for their prevention. Antiviral and immunomodulating action is possessed by the German preparation "Imupret". It consists of field horsetail, walnut leaves and oak bark.
The price of antiviral drugs for colds
The run-up of prices for antiviral drugs for colds is quite wide - from 20 to 200 hryvnia (of course, it still depends on the packaging and the number of tablets). In any case, it is better to consult with the attending physician who will prescribe the drug, which in the particular case will prove to be the most effective.
If you call the approximate prices for the main antiviral drugs used to treat colds, in pharmacies in Ukraine they are: "Amizon" - from 20 UAH, "Arbidol" - from 50 UAH, "Amiksin" - from 30 UAH, "Anaferon" - from 40 UAH, "Remantadin" - from 11 UAH, "Kagocel" from 70 UAH, "Viferon" - from 70 UAH - from 110 UAH.
Inexpensive antiviral drugs for colds
Inexpensive antiviral drugs for colds, often prescribed by doctors and commonly used - Amizon, Amiksin, Anaferon. For 20-40 hryvnia you can buy 10 tablets. But once again pay attention: before making a decision to purchase an antiviral drug for a cold, it is worth consulting with the treating doctor.
With the help of antiviral drugs, it is not the consequence, but the cause of the catarrhal disease that is eliminated. This is the great advantage of antiviral drugs in the treatment of colds, which also explains their effectiveness. Antiviral drugs shorten the cold for two to three days, ease its course. Due to the use of antiviral drugs for colds, the risk of other chronic diseases worsening (exacerbation bronchial asthma, chronic bronchitis and other diseases), also there will be no various complications, as often happens with other preparations. In addition, antiviral drugs for colds give excellent effect in the prevention of acute respiratory viral infections, influenza, including among healthy family members when the patient is at home.
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