Staphylococcus bacteriophage: user manual, reviews of people

Staphylococcal bacteriophage is a bacterial virus that can only kill staphylococcus strains.

It is believed that in one second a bacteriophage is able to infect about 10 3 of bacterial cells. Especially they work well against bacteria, which have a dense polysaccharide cell membrane, through which antibiotics are difficult to penetrate. In such cases, phagotherapy is an advantage over antibiotic treatment.

On this page you will find all information about Staphylococcus aureus: the full instructions for use for this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Staphylococcus bacteriophage. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antibacterial action.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much is a Staphylococcus bacteriophage? The average price in pharmacies is at the level of750 rubles.

Form of issue and composition

This preparation is available in the following forms and formulations:

1. In liquid form / vials of 100.50.20 milliliters and aerosols of 25 ml.
2. In the form of ointments, 10 and 20 grams.
3. In candles (10 pieces in one package).

This drug is a product in the liquid form of a bacterial culture and is a combination of bacterial cell particles and a particular nutrient medium that contains bacteriophage particles. This product is active against the following staphylococci (golden, epidermal, saprophytic).

Pharmacological effect

Staphylococcus a bacteriophage is a drug that has a specific effect on staphylococci of the most common strains. When combined with a bacterium, it dissolves it, and the residue of decay removes it from the body.

It is an antibacterial preparation of immunobiological influence and is prescribed for the treatment of infectious diseases caused by staphylococci. A wide range of effects on pathogenic strains gives effective results in complex treatment. Does not affect the beneficial bacteria found in the human body.

Indications for use

Staphylococcal bacteriophage is used to treat:

• generalized sepsis and peritonitis;
• Other diseases caused by the spread of staphylococcus;
• surgical infectious diseases (wounds with pus, burns with attached infection, hydrodenite, pandactylitis, mastitis, paraprotkit and others);
• pathology of the urogenital system (almost all diseases of the urinary and reproductive systems);
• gastroenteral pathology (inflammation of the mucosa, dysbacteriosis and others);
• diseases of the upper respiratory tract and bronchopulmonary system; to these include various kinds of sinusitis, rhinitis, acute and chronic tonsillitis, otitis media, pharyngolaryngitis, tracheobronchitis, pneumonia and pleurisy);
• as a preventive measure for fresh infected wounds (after surgery in the abdominal and thoracic cavities);
• as prevention of the development of nosocomial infections.

It is very important for the effective phage therapy to determine the phagosensitivity of the pathogen first, this is the sensitivity to the staphylococcal bacteriophage strains selected from the patient.

Advantages over antibiotics

Bacteriophage has an antibacterial effect. They also have antibiotic drugs. Medicines for several criteria differ from each other. Judging by the reviews, the bacteriophage has undeniable advantages, which make it possible to make a choice in favor of it, rather than antibiotics.

These advantages are as follows:

• can be prescribed for the purpose of prevention;
• is allowed for people of any age, even for babies;
• is not prohibited for pregnant and lactating women;
• have no contraindications;
• Effective against microorganisms that are insensitive to antibiotics;
• can be used with all other medicines, including antibiotics;
• does not depress human immunity;
• does not lead to the development of resistant to phages crops;
• Do not destroy the beneficial bacterial microflora;
• do not lead to addiction;
• has an immunomodulatory effect.

Contraindications

According to the instructions, Staphylococcus bacteriophage is contraindicated in cases of hypersensitivity or intolerance to the components of the drug.

Application in pregnancy and lactation

The absence of serious contraindications and side effects enabled the use of the Antistaphylococcal Bacteriophage in the treatment of infections in pregnant women. Important condition - therapy should be prescribed only by a doctor and carried out under his supervision. In addition, a bacteriophage of this type is also prescribed only if the mother has an infection caused by staphylococci.

Instructions for use

The instructions for use indicate that the Staphylococcus bacteriophage is intended for local, rectal and oral administration. Before use, shake the bottle, if there is a visible residue or change in transparency, the solution should not be used. To achieve maximum therapeutic effect, treatment should be started as soon as possible after the onset of symptoms of the disease. The duration of therapy, the scheme of application of the drug and the dose is determined by the doctor.

Recommended single doses for patients of different age groups:

• Adults and children over 8 years of age are recommended to administer 30 ml of a solution of Staphylococcal bacteriophage orally and 50 ml of the drug for rectal administration;
• For children 3-8 years, rectally, as a rule, 40 ml of a bacteriophage are prescribed, orally - 20 ml of the drug;
• For children 1-3 years rectally, as a rule, 30 ml of a bacteriophage are prescribed, orally 15 ml of the preparation;
• Children 6-12 months rectally, as a rule, 20 ml of a bacteriophage are appointed, orally - 10 ml of the drug;
• Children younger than 6 months rectally, usually prescribed 10 ml of bacteriophage, orally - 5 ml of the drug. The first dose of the drug should be administered in the form of high enemas, unless there is a development of regurgitation, digestive disorders and other undesirable effects, the bacteriophage can be administered orally or orally and rectally.

The average duration of therapy is from 7 to 20 days. With relapsing forms of diseases, several courses of the Staphylococcus bacteriophage preparation can be prescribed per year.

Locally the drug is used depending on the location of the infection:

1. In surgical practice, the solution is used in the form of rinsings, irrigation, tamponing, and also for introduction into drained or confined cavities;
2. In gynecological practice, the drug is used in the form of irrigation, applications and tampons moistened with a solution;
3. In otolaryngological practice, the solution is used for washing, irrigation, wetting sterile turundas, and also as nasal and ear drops;
4. Introduction to the joint, pleural and other limited cavities, including the drained cavity of the bladder and renal pelvis, through capillary drainage, nephrostomy or cystostomy;
5. When intestinal diseases are prescribed rectal administration of a bacteriophage (in conjunction with ingestion).

It should be borne in mind that if before the local application of the preparation Staphylococcus a bacteriophage was treated with chemical antiseptics, then before the use of the bacteriophage should be washed skin patch isotonic sodium chloride solution.

Side effects

During the study of the drug, side effects from its use were not established. Judging by the reviews, they are noted only with intradermal administration. There may be inflammation and hyperemia, but they are of a short-term nature.

Overdose

Symptoms in case of an overdose of Bacteriophage have not been studied, so the instructions for the use of the drug are also not described.

special instructions

When opening the vial, storing and selecting the remedy, the following rules should be observed:

1. Wash hands thoroughly;
2. Before removal, the cap must be treated with an alcohol solution;
3. Remove the cap without removing the stopper;
4. The preparation from the opened vial should be selected only by piercing the plug with a sterile syringe;
5. If the plug was accidentally uncorked with the cap at the opening, then it should not be put on the inside surface on the table, and the bottle is forbidden to leave open (after selection of the means it needs to be closed with a cork);
6. It is recommended to store the opened bottle in the refrigerator.

Subject to compliance with these rules and in the absence of turbidity, the product from the opened bottle is allowed to be used throughout the shelf life.

Drug Interactions

The use of the drug is possible in combination with other drugs, including antibiotics.

Reviews

Reviews about Staphylococcus bacteriophage are predominantly positive. Patients confirm the high effectiveness of the drug in the fight against diseases caused by staphylococci, and consider it a worthy and safer alternative to antibiotics. However, there are also individual reviews, which indicate that the bacteriophage was ineffective and even caused side effects (diarrhea, increase in body temperature), although the instructions indicate a very good tolerability of the drug and no undesirable reactions.

To the disadvantages, almost all patients attribute the high cost of Staphylococcus a bacteriophage and its unpleasant taste, as well as the inconvenience storage (in the refrigerator) and use (the need to take a solution with a sterile syringe to comply with aseptic).

Analogues

Staphylococcus bacteriophage has a number of drugs that are similar to it according to the principle of action, i.e. also having an antibacterial effect against certain pathogenic microorganisms. Such means include:

• 5-Knock;
• Trobitsin;
• Fortrease;
• Dioxydin;
• Monural;
• Cubicin;
• Fosmicin;
• Kirin;
• Nitroxoline.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Storage at a temperature of 2 to 8 ° C in a place protected from light and inaccessible to children. Transportation at a temperature of 2 to 8 ° C, transportation is allowed at a temperature of 9 to 25 ° C for not more than 1 month.

Shelf life 2 years. The drug with expired shelf life is not subject to application.

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