Diazoline is an antiallergic drug.
It belongs to a group of drugs that are capable of blocking receptors for histamine (the main mediator of allergic reactions). This medication significantly influences the permeability of small vessels, which inhibits the development of edema of tissues, and also eliminates itching.
On this page you will find all information about the Diazolin: the full instruction on the administration of this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Diazolin. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
The blocker of histamine H1 receptors, the derivative of ethylenediamine.
Conditions of leave from pharmacies
Available without a prescription.
Price list
How much does Diazolin cost? The average price in pharmacies is at the level of110 rubles.
.Form of issue and composition
In pharmacies sold Diazoline in the form of tablets or dragees. Each white tablet has a risk and a chamfer. The weight of each tablet is 10 mg. Dragee or tablets are placed in a contoured honeycomb package.
Presented for sale in the form of tablets and tablets, Diazoline in its composition has the following substances:
- Mebhydrolin or Mebydrolin;
- histamine receptor blockers.
Auxiliary substances are lactose monohydrate, microcrystalline cellulose, aerosil, potato starch, magnesium stearate.
Pharmacological effect
The active component of Diazoline (mebhydroline) has a pronounced antiallergic effect and, blocking H1-histamine receptors, helps to reduce edema of the mucous membranes.
A distinctive property of Diazolin in comparison with antihistamine medicines of the first generation is the absence of a pronounced hypnotic and sedative effect. In this case, adult and children's Diazolin effectively affect the smooth muscles of the uterus, bronchi and intestines, as well as reduce the severity of increased vascular permeability and lowering of arterial pressure.
The action of Diazoline, according to the instructions, is observed after half an hour after administration, and its duration can reach two days.
Indications for use
What helps? Indications Diazolin include the following diseases and conditions:
- an allergic rhinitis;
- urticaria;
- itching with dermatosis;
- insect bites;
- seasonal rhinitis;
- Pollinosis;
- food and drug allergy.
The drug is prescribed for both therapy and prevention of the listed pathologies.
Contraindications
Restrictions for taking any form of the drug Diazolin:
- epilepsy;
- pyloric stenosis;
- lactation period;
- heart rhythm disorder;
- ulcerative lesions of the digestive tract;
- angle-closure glaucoma;
- intolerance to the active substance;
- inflammation of the mucous membranes of the stomach, intestines;
- pregnancy (I and II trimester - categorical prohibition, III trimester - only with the permission of the doctor, taking into account the possible positive effect for the mother and risks for the fetus).
Severe renal or hepatic pathologies require an evaluation of the therapeutic effect of an antihistamine drug and possible risks to the body. When appointing an antiallergic agent to patients with kidney and liver problems, the doctor adjusts the dosage and frequency of admission.
Application in pregnancy and lactation
Due to the fact that Diazolin penetrates the placental barrier, it is not recommended to take it during pregnancy, especially in its first 12 weeks. In the future, Diazoline can be taken in short courses - no longer than 3-5 days. And although Diazolin is considered to be a relatively safe drug, there is not enough data accumulated during its use to judge its absolute harmlessness to the fetus.
The same applies to the intake of Diazoline in lactation - the drug easily penetrates into breast milk.
Instructions for use
In the instructions for use, it is indicated to take tablets / dragees. Diazoline is recommended during or after a meal, without chewing and drinking with a sufficient amount of still water.
Depending on the severity of the disease, the daily dose may be:
- For adults and children over 10 years old - from 100 to 300 mg (100 mg 1-3 times a day);
- For children 5-10 years - 100-200 mg (50 mg 2-4 times a day);
- For children 2-5 years - from 50 to 150 mg (50 mg 2 or 3 times a day);
- For children under 2 years of age - 50-100 mg (50 mg 1 or 2 times a day).
- Maximum permissible daily doses for adults: single dose - 300 mg, daily - 600 mg.
Duration of administration of Diazoline is determined by the nature of the disease and the effectiveness of the therapy. As a rule, it is 3-7 days. If you need a longer treatment, another drug is prescribed.
Side effects
Negative effects on the body are less pronounced than after taking other drugs of the 1st generation, but negative reactions appear more often than with the use of modern antiallergic compositions. The patient should receive information about possible side effects before starting therapy.
Negative reactions after taking Diazoline may be expressed as:
- drowsiness;
- dry mouth;
- increased fatigue;
- nausea;
- allergy;
- heartburn;
- granulocytopenia;
- pain in the abdomen;
- slowing down the reaction;
- agranulocytosis;
- irritation of the gastric mucosa;
- dizziness;
- a violation of urination.
Overdose
With systematic overestimation of prescribed daily doses, cases of overdose were documented. In such clinical pictures, the severity of side effects is only increasing, an urgent correction of daily dosages is required. Patients with stomach disease need to be especially apprehensive, because doctors do not rule out relapse of the underlying disease.
special instructions
Diazolin therapy is ineffective in bronchial asthma and anaphylactic shock.
During the treatment period, care must be taken when driving vehicles and occupying others Potentially hazardous activities requiring increased concentration and speed psychomotor reactions.
Drug Interactions
The drug is not recommended to be combined with other antihistamines, as this increases the risk of side effects and drug overdose.
There is no data on any other interaction with the drug, but if the patient is already taking any medications, the doctor should be warned about this.
Reviews
We picked up some of the people's comments about Diazolin:
- Artem. With Diazolinum be careful, take only before going to sleep, otherwise you can fall asleep both behind the wheel and at work.
- Nona. Diazoline is considered to be the most effective and harmless drug against allergies. Any redness, sneezing and even a slight cough of an allergic nature, this drug quickly removes. Always give a child when the street begins blooming - for prevention. Or when I give the child any medicines to avoid allergies to them.
- Larissa. I somehow was treated for an allergy to oranges with the help of diazoline. I took a week, three times a day for one tablet. And then somehow my stools became almost black. I did not drink any more medicine. Why do I know such a reaction to diazoline? I have gastritis in mild form, but it's not a very serious illness. In contra-indications about a gastritis words are not told or said, and ulcers at me are not present. The stomach also does not hurt at all, only here the color of me is alarming.
Analogues
For drugs that have a similar effect and can be prescribed for allergies of any nature, include:
- Omeril;
- Mebhydrogen;
- Dialalin;
- Mebhydroline naphthalene -disulfonate.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Store Diazolin in a dry place in the absence of light. Storage temperature - no more than 25 degrees.
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