Proctosedil

Proctosedil is the original combination drug for topical application in proctologic practice.

Used for hemorrhoids and other diseases of the anorectal region. It exhibits pronounced anti-inflammatory, antipruritic, antibacterial, angioprotective and local anesthetic activity.

The effect of the drug is due to the properties of its constituent components - hydrocortisone, benzocaine, frameamycin, esculoside, butamben and heparin.

Clinical and pharmacological group

The drug with anti-inflammatory, antibacterial, antithrombotic and local anesthetic action for topical application in proctology.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Proctosidil in pharmacies cost? The average price is at the level of400 rubles.

Form of issue and composition

The drug is available in 2 dosage forms - in the form of ointments and suppositories.

Ointment Proctosedil is designed for rectal and external use. Packaging of the preparation is carried out in tubes of aluminum, laminated foil in the calculation of 10 g per tube. In a cardboard bundle contains 1 tuba with ointment. In the kit there is a special nozzle-applicator for the convenience of self-application of the drug in the anorectal area.

Suppositories have a rather unusual form for rectal suppositories. They look like a light, cream-colored capsule in the form of an oval. On the one hand, the oval is pointed. The touch of the capsule is soft and supple. The implementation of Candles Proctosedil takes place in vials, the color of the glass in which is dark. Each bottle contains 20 suppositories. A pack of cardboard.

Pharmacological effect

Proctosedil is a complex external preparation. The composition of Proctosedil includes several active components:

1. Eskulozid - a substance that reduces the fragility of capillaries.
2. Heparin is an anticoagulant that prevents blood clotting.
3. Butamben is an anesthetic that exerts an analgesic and antipruritic effect.
4. Benzocaine has an analgesic effect, is intended for topical application.
5. Hydrocortisone is a glucocorticosteroid, it relieves inflammation and allergy symptoms.
6. Framicetin is an antibiotic intended for topical application, inhibitory activity of Klebsiella, enterobacter, Shigella, Proteus, Salmonella, Pseudomonas aeruginosa, certain Streptococcus strains and Staphylococci.

Thus, the effects of Proctosedil components are complex. Butyl aminobenzoate, ethyl aminobenzoate, esculoside, armacetin and esculoside are practically not absorbed into the bloodstream. Hydrocortisone - absorbed into the bloodstream only partially, but half-excreted within 90 minutes.

Reviews of Proctosedil indicate that its effect is manifested after 2-5 minutes after application.

Indications for use

In medical practice, Proctosedil is indicated for the treatment of the following ailments:

• anal fissure;
• complicated and not complicated proctitis;
• perianal eczema;
• itching of the anorectal region;
• prevention of recurrence of hemorrhoids;
• exacerbation of hemorrhoids with different symptoms;
• internal chronic hemorrhoids;
• external chronic type of hemorrhoids;
• preoperative and postoperative therapy of patients.

Due to the fact that the drug is a bactericide of high efficiency, it is often used to treat skin infections.

Contraindications

Candles Proctosedil from hemorrhoids can not be used in patients with known hypersensitivity to any of the constituents of the drug, as well as:

• at tubercular, viral, fungal lesions of the anorectal zone;
• neoplasms in the rectal passage;
• pregnant and breastfeeding patients, as well as children.

Patients with hypertension or cardiac insufficiency should apply the drug with caution.

Use in pregnancy and lactation

Contraindicated use of the drug during pregnancy and during breastfeeding.

Dosage and route of administration

The instructions for use indicate that Proctosedil is used externally. A small amount of ointment should be applied to the areas of itching or pain localization in the morning and evening, and after each defecation.

• For a deeper introduction into the rectum, you should put the applicator on a tube with ointment, insert it into the rectum, make sure that it is introduced enough deep into the rectum, and then, gently pressing the tube from the lower end, to introduce ointment into the rectum, gradually removing the applicator.

Ointment can be used alone or in combination with rectal capsules Proctoside M.

Proctosedil is applied for a short time (not more than 7 days).

Candles

Rectal suppository Proctosedil is applied daily, injected one candle in the evening, in the morning and after each act of defecation.

The frequency of application of the ointment is the same. The agent is applied to the area of ​​the anal opening, to those areas where pain or itching is felt or injected into the anus with a special applicator.

Ointment and rectal suppository Proctosedil use no more than a week.

Side effects

1. Of the side effects of the drug there is a feeling of discomfort and burning in the rectum, the appearance of dryness of the mucous membrane. Against this background, it is possible to attach a secondary infection.
2. Sometimes allergic reactions occur on the use of the ointment, in such cases, the drug should be discontinued and consult a doctor to adjust the course of therapy.

The instruction to the preparation notes that the use of the ointment for a long time or in high doses is undesirable, since there is a risk of developing systemic side effects associated with hydrocortisone.

Overdose

Data not provided by the manufacturer.

special instructions

With caution should be used in patients with arterial hypertension, heart failure.

Drug Interactions

Systemic absorption, and, accordingly, interaction with other drugs in the preparation of Proctosedil is minimal.

Reviews

We picked up some feedback from people who used Proctosedil:

1. Oksana. Her husband often has hemorrhoids, after lifting heavy or drunk alcohol, and after using something sharp. Candles he does not recognize and until some time he was treated with the ointment Proctosidil. And most importantly, she helped him, took off painful sensations, removed inflammation. Usually everything came back to normal after a week, there were a little more or a little less. Hanging from the degree of inflammation. The last time, and it was about 2 weeks ago, ointment did not help. About 2 weeks of its use, they realized that it's time to apply something else, and apply ointment as an auxiliary.
2. Pauline. Prokosedil always is in my medicine cabinet as I lead a sedentary lifestyle and sometimes suffer from constipation. For me, this is one of the most effective drugs for hemorrhoids. Within literally 2-3 days, it effectively relieves pain, eliminates itching and dryness. I did not feel any side effects on myself. While other medications were used, other more severe symptoms developed, but with proctosyltil to this did not reach, everything passes very quickly.
3. Irina. Proctosedil in capsules is a sophisticated mockery of patients, which must be immediately modified and manufactured in the form of normal candles. Capsules are not inserted in any way - neither by themselves, nor with the use of ointment, nor by pushing their other candles, nor by attaching to a cut candle! What more imagination is needed to figure out how to insert them?

Analogues

Structural analogs for the active substance:

• Proctosedil M.

Analogues for the pharmacological group (means for the treatment of hemorrhoids):

• Avenok;
• Agiolax;
• Bisacodyl;
• Butadione;
• Vasoket;
• Venarus;
• Veno-comfort;
• Venoruton;
• Heparoid Lechiva;
• Hepatrombin;
• Hyposol;
• Glaxen;
• Guttalax;
• Derinat;
• Detraleks;
• Doloproct;
• Dulcolax;
• Laxatin;
• Laxigal;
• Metrogil;
• Natalside;
• Nefluen;
• Novocaine;
• Normase;
• Olesesin;
• Papaverine;
• Posterizan;
• Posterizan forte;
• Pramoxin;
• Procto Glivenol;
• Proctosan;
• Relief Ultra;
• Romazulan;
• Romfalak;
• Rutin;
• Senadé;
• Senna;
• Weak;
• Tyqveol;
• Ultraproject;
• Fiberleks;
• Flebodia 600;
• Heferol;
• Escuzan;
• Escolus;
• Ethoxysclerol.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep out of the reach of children at a temperature of no higher than 25 ° C. Shelf life - 2 years.

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