Ulkavis

Ulkavis is an antiulcer, which also has an astringent and anti-inflammatory effect. It is active against the bacterium Helicobacter pylori (it acts bactericidal).

The drug increases the formation of mucus, increases the synthesis of prostaglandin E and the secretion of bicarbonate, resulting in stimulated activity cytoprotective mechanisms and increases the resistance of the mucous membrane of the gastrointestinal tract to the effects of hydrochloric acid, pepsin, bile salts acids and enzymes.

Ulkavis promotes the accumulation of a special protein (epidermal growth factor) in the affected area, and also reduces the activity of pepsin.

Clinical and pharmacological group

Antiulcer agent with bactericidal activity against Helicobacter pylori.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much does Ulkavis cost in pharmacies? The average price is at the level of220 rubles.

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Composition and form of release

Ulkavis is available in the form of tablets coated with a film shell: white or almost white, round, slightly biconcave, with a facet; At the break, a white core and a white or almost white shell (10 pieces each; in blisters, in a cardboard bundle 3, 4, 6, 10 or 24 blisters; for 14 pcs. in blisters, in a cardboard bundle of 2, 4, 8 or 16 blisters; 15 pieces each. in blisters, in a cardboard bundle of 2, 4, 8 or 16 blisters).

Composition per 1 tablet:

• active ingredient: bismuth oxide - 120 mg (in the form of bismuth, tricalium dicitrate in an amount of 30, 3 mg);
• auxiliary components: povidone K30, macrogol 6000, corn starch, potassium polucrilin, magnesium stearate;
• film shell: titanium dioxide, Opadrai II transparent (talc, macrogol 4000, polyvinyl alcohol).

Pharmacological effect

Ulkavis also has an anti-inflammatory and astringent effect. Insoluble bismuth oxychloride and citrate are precipitated in the acidic environment of the stomach, and chelate compounds are formed with the protein substrate in the form of a protective film on the surface of ulcers and erosions.

Increasing the synthesis of prostaglandin E, the formation of mucus and the secretion of bicarbonate, stimulates the activity of cytoprotective mechanisms, increases the stability of the mucous membrane of the gastrointestinal tract to the effects of pepsin, hydrochloric acid, enzymes and bile salts acids.

It leads to the accumulation of the epidermal growth factor in the defect area. Reduces the activity of pepsin and pepsinogen.

Indications for use

This medication is the main or auxiliary treatment of a number of acute or chronic diseases of the digestive system. According to the detailed instructions, the main indications for the use of Ulkavis are presented below:

• gastritis of the exacerbation stage;
• recurrent gastroduodenitis;
• functional dyspepsia;
• stomach ulcer;
• irritable bowel syndrome.

Contraindications

Tablets Ulkavis can be taken only as prescribed by a doctor, contraindications to the use of the drug are:

• renal failure in the stage of decompensation;
• children under 4 years;
• individual intolerance to the components of the drug;
• lactation period;
• pregnancy.

Intended use for pregnancy and lactation

The use of Ulkavis tablets during pregnancy is contraindicated, since there is no experience of using the drug and data confirming the safety of the medication for the fetus.

During breastfeeding, the drug should not be taken orally, since the active ingredient of the tablets is excreted in breast milk. If it is necessary to treat Ulkavis, lactation should be discontinued.

Dosage and route of administration

As indicated in the instructions for use, Ulquivis tablets are taken orally with a small amount of water half an hour before meals.

Recommended dosage of the drug:

• children from 12 years and adults: 1 tablet 4 times a day (before meals and at night) or 2 tablets 2 times a day;
• children 8-12 years: 1 tablet 2 times a day;
• children 4-8 years: 1-2 tablets in 1-2 divided doses, but not more than 8 mg / kg / day.

Duration of treatment is from 4 to 8 weeks.

For eradication of bacterium H. pylori Ulkavis is advisable to appoint in combination with other antibacterial drugs that are characterized by anti-Helicobacter pylori activity.

Adverse Reactions

There are side effects from the gastrointestinal tract (rapid chair, vomiting, nausea, constipation), but they are transient in nature and not dangerous to human health. The drug can also cause allergic reactions in the form of itching and rash.

With prolonged therapy with Ulcavis in high doses, bismuth accumulates in nerve cells, which can lead to the development of encephalopathy.

Overdose

Symptoms: an overdose of Ulquivis, caused by prolonged intake of doses exceeding the recommended dose, can lead to impaired renal function. These symptoms are completely reversible with the withdrawal of Ulkavis.

Treatment: gastric lavage, the appointment of activated charcoal and saline laxatives. In the future, treatment should be symptomatic. In the case of a violation of kidney function, which is accompanied by a high concentration of bismuth in blood plasma, chelating agents (penicillamine, sodium dimercaptopropanesulfonate) can be prescribed. In the case of pronounced impaired renal function, hemodialysis is indicated.

special instructions

Do not use for more than 8 weeks.

During treatment it is not recommended to exceed the established daily doses for adults and children.

At the end of the course treatment at recommended doses, the concentration of active substance in the blood plasma does not exceed 3-58 μg / l, and intoxication is observed only at a concentration of more than 100 μg / l.

Against the background of application, it is possible to stain the feces black due to the formation of bismuth sulphide. Sometimes there is a slight darkening of the tongue.

Interaction with other drugs

Within half an hour before and after taking the drug, Ulcavis does not recommend the use of other medicines inside, as well as ingestion of food and liquids, in particular antacids, milk, fruits and fruit juices. This is due to the fact that they can affect the effectiveness of Ulkavis when taken concomitantly.

Simultaneous use of Ulcasis with tetracycline reduces the absorption of the latter.

Reviews

We offer you to read reviews of people who used Ulkavis:

1. Victoria. I have gastritis for a long time. He did not bother eight years. Recently, exacerbation began, the stomach became very ill. I eat boiled oatmeal, mashed potatoes, soups. Completely ruled out everything fried, spicy and sour. Salt, too, is afraid. Meat only for a couple. And every day I drink two tablets twice a day. He helped me very well from pain. The stomach has ceased to hurt. The doctor says the main thing is not to leave. Drink the whole course and continue on a diet to sit, but we'll see.
2. Artem. When I have a seasonal exacerbation of gastritis, I use Ulkavis tablets alone for a full course of 3-4 weeks. Relief comes almost instantly, stops so much ache, returns a lost appetite. The drug does not cause side effects, acts quickly and gently. Available in all pharmacies, it is inexpensive.
3. Nastya. In combination with Ulkavis cured gastritis by 100%. Previous treatment only stopped the disease for a while, while there were such unpleasant sensations as heartburn and colic. Rarely of course, but still the pains were, if for example the transfer of something greasy or sour. I had to limit myself to eating, knowing that it would not be pleasant then. After the last course of treatment, which included Ulkavis, I completely lost all the symptoms of gastritis and have not returned for a very long time. Examination has shown!)

Analogues

If the medication does not improve overall well-being or provokes side effects, the doctor introduces a substitute. When choosing an analogue of Ulkavis, it is recommended to pay attention to such pharmacological positions:

1. Novobispol (tablets). Gastroprotective agent with bismuth in the composition. Take inside 1 tablet three times a day for a month.
2. De-Nol (tablets). It is an antibacterial, antiulcer medication for peptic ulcer. It is recommended to drink 1 tablet 4 times a day for 3-4 weeks.
3. Escape (tablets). Antiulcer drug, which is also supposed to take 1 pc. 4 times a day for a month.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Keep out of reach of children at a temperature of no higher than 25 ° C.

Shelf life - 2 years.

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