Chondroitin

Chondroitin is a drug-chondroprotektor, aimed at stimulating regenerative processes in bone tissue. Active ingredient is the same active substance chondroitin.

The action of this medication is aimed at regulating metabolic processes in the cartilaginous tissue. Chondroitin belongs to a number of chondroprotectors (stimulators of cartilage tissue regeneration).

The active substance of the preparation is a high-molecular polysaccharide, which is obtained from the cartilage of the trachea of ​​cattle. The drug affects the metabolism of hyaline and fibrous cartilage, while reducing degenerative processes in the joint tissue and activating the production of glycosaminoglycans.

The drug produces a retarding effect on bone resorption and reduces the washing out of calcium, thereby contributing to the regeneration of bone tissue.

Clinical and pharmacological group

The agent that affects the phosphorus-calcium metabolism in the cartilaginous tissue is a high molecular weight mucopolysaccharide.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

The price for chondroitin depends on the form of release of the drug and may be approximately:

• capsules 250 mg (50 pcs. in the package) - from 310 to 360 rubles;
• gel for external use 5% (30 g per pack) - from 70 rubles;
• ointment for external use 5% (30 grams per pack) - from 60 rubles.

Composition and form of release

This drug is available in the form of a gel and capsules.

1 capsule contains:

• active ingredient: chondroitin sulfate 250 mg;
• additional components: calcium stearate, lactose (sugar milk);
• capsule shell: methylparaben, gelatin, propylparaben, sodium lauryl sulfate, water, titanium dioxide (E 171).

In 1 g of ointment contains:

• active substance: chondroitin sodium sulfate - 50 mg (in terms of dry matter);
• additional components: lanolin, dimethylsulfoxide, petrolatum, purified water.

In 1 g of gel contains:

• active substance: chondroitin sulfate - 50 mg;
• Additional components: disodium edetate, dimethoxide (dimethyl sulfoxide), methyl parahydroxybenzoate (nipagin), propylene glycol, macrogol glycerol hydroxy stearate, lavender oil, orange oil (neroli oil), trolamine (triethanolamine), carbomer, purified water.

Pharmacological effect

The main active component of the analyte is chondroitin sulfate. This substance is a high molecular weight mucopolysaccharide of animal origin, which is obtained from cartilage of the trachea of ​​cattle. The main actions of chondroitin sulfate are:

1. Activation of biosynthesis in chondrocytes of glycosaminoglycans.
2. Normalization of metabolism in hyaline tissue.
3. The inhibition of calcium loss in the cartilaginous tissue, as well as bone tissue.
4. Increase in intra-articular fluid production.
5. Influence on metabolism in hyaline and fibrous cartilage.
6. Reduction of degenerative changes in articular cartilage.
7. Suppression of the activity of enzymes that cause damage to cartilaginous tissue.
8. Improvement of phosphorus and calcium metabolism.
9. Stimulation of regeneration of cartilage surfaces and bags of joints.

Chondroitin promotes the restoration of cartilage in the joints, increasing their mobility. Also, this remedy reduces the soreness of the affected joint.

Dimethyl sulfoxide, which is part of the drug, has a fibrinolytic, anti-inflammatory and analgesic Effects, which allows the active component to penetrate the cell membranes deep into the tissues.

Indications for use

The drug with chondroitin sulfate is recommended for the following articular pathologies:

• osteocondritis of the spine;
• osteoarthritis.

The drug is recommended for the prevention of degenerative-destructive changes in the spine and joints. Capsules and ointment are allowed only for the doctor's prescription.

Contraindications

Before taking capsules, you should carefully read the attached instructions, since chondroitin has a number of contraindications for use:

• age up to 15 years;
• pregnancy and the period of breastfeeding;
• individual intolerance to the components of the drug;
• congenital lactose intolerance, malabsorption syndrome;
• liver disease, accompanied by a marked disruption of the body.

Relative contraindications to the use of capsules are violations of blood clotting in the patient, a tendency to thrombophlebitis.

Intended use for pregnancy and lactation

Experience in the use of capsules Chondroitin during pregnancy is absent or limited, so future mothers do not prescribe this drug. Data on the safety of the drug for the mother and its influence on intrauterine development of the fetus are not provided.

Capsules should not be taken orally during breastfeeding, since the active ingredient of the drug can be excreted in breast milk and enter the child's body. If you need a course of treatment with a lactating mother, you should think about the completion of lactation and the transfer of the child to artificial feeding.

Dosage and route of administration

As indicated in the instructions for the use of capsules, chondroitin is taken orally, with water, 2 times per day: for the first 3 weeks - 3 capsules (750 mg), then - 2 capsules (500 mg).

• The recommended initial course is 6 months, after its completion, the therapeutic effect of the drug, depending on the stage and localization of the lesion, persists for 3-5 months.

The duration of repeated courses is determined by the attending physician.

Gel and cream

The gel and cream are used externally, applying to the skin over the lesion site 2-3 times a day. The drug should be rubbed into the problem area for 2-3 minutes, until completely absorbed. The duration of the ointment is 2-3 weeks, the gel is from 2 to 8 weeks. If necessary, the appointment of a second course is possible.

Adverse Reactions

Against the background of the use of the drug of the aetiology of chondroitin, nausea or vomiting may occur. These clinical manifestations are extremely rare. Also, there is a possibility of skin erythema, urticaria and skin itching, which are also characterized by a very low frequency of occurrence.

Overdose

When using capsules in rare cases, symptoms of an overdose may include such disorders as diarrhea, nausea, vomiting; with prolonged intake of too high doses (more than 3 g), hemorrhagic eruptions may occur. In this condition, gastric lavage and symptomatic treatment are prescribed.

Cases of overdose of chondroitin in external application have not been registered to date.

special instructions

With different forms of paradontopathy, treatment should be continued for at least 3 months.

There are clinical data on the use of chondroitin sulfate in elderly patients with atherosclerosis, with a slight decrease in the concentration of cholesterol and triglycerides in the blood plasma.

Compatibility with other drugs

May enhance the effect of antiaggregants, fibrinolytics, indirect anticoagulants. In addition, the active substance of the drug increases the degree of absorption of tetracyclines, and also reduces the absorption of Chloramphenicol and penicillins.

Reviews

We offer you to read reviews of people who used chondroitin:

1. Vladislav. At me a gout, I accepted chondroitin, me pomoglo.na 6 months I have forgotten that such pains in joints. It's time to repeat the course, because the pain starts again. Helps chondroitin, glucosamine and chondroitin sulfate, you need to consult with your doctor who exactly he will prescribe after taking the tests.
2. Inna. The knees hurt very badly, especially when you need to go up and down the stairs. In the mornings she got out of bed with great difficulty. The doctor diagnosed arthrosis, appointed to do injections of Mukosata. A month later I felt better, it became easier to move around, pains decreased. The only drawback is the high price of the medicine.
3. Yana. Have diagnosed a chronic osteochondrosis, although he, probably, every fifth. I was not helped by any drugs, the pain did not go away. The neurologist prescribed "chondroitin" twice a year, after the first time it became much easier. Previously it came to that I could not get out of bed, strain my arm, turn my head, eternal dizziness. And now, the strongest attack is tight muscles, as if something is interfering. Everything goes much faster. Let it be expensive, but it's worth it.

Analogues

Doctors prescribe to patients with joint diseases the drugs, which are analogues of chondroitin sulfate. The drugs have the same active substance. Popular medicines:

• Teraflex. It stops the destruction of the cartilaginous tissue, accelerates regeneration, maintains the viscosity of the synovial fluid. The price is 1450 rubles for 60 capsules.
• Artadol. It is used for intramuscular injection. Improves mobility of joints, normalizes the production of joint fluid, reduces pain. The price is 600 rubles. for 10 ampoules of lyophilizate.

Good results in the treatment of the pathology of the joints and bones are:

• Arthrin. Helps the rapid formation of bone calluses in the case of bone fractures, relieves inflammation, reduces swelling, bruises, is an analgesic. The price for 36 capsules is 290 rubles.
• Mukosat. It stops the degeneration of cartilaginous tissues, activates the production of joint fluid, improves metabolic processes, mobility. The price is 360 rubles. for 5 ampoules.
• Arthron chondrex. Stimulates the regeneration of cartilaginous tissues, increases elasticity, reduces pain at rest, while moving. The price is 1150 rubles. for 60 tablets.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Store in a place inaccessible to children, protected from penetration of light and moisture, capsules and gel - at a temperature of up to 25 ° C, ointment - up to 20 ° C.

Shelf life of capsules and gel - 2 years, ointments - 3 years.

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