Tabex from smoking

Tabex - a drug for the treatment of nicotine dependence of the group of n-holinomimetikov from the Bulgarian pharmaceutical company "Sopharma".

The active ingredient of the drug is the alkaloid cytisine, extracted from the broom. He interacts with n-holinoretseptorami, acting as an antagonist nicotine. Cytisine stimulates the receptors of the ganglions of the vegetative nervous system, stimulates the chemoreceptors located in the place expansion of the internal carotid artery (the so-called carotid sinus) and promotes more intensive secretion of epinephrine with bark adrenal glands.

The drug does not affect the psychophysical state and does not worsen the ability to engage in activities that require concentration and attention. With a nicotine-like mechanism of action, cytisine has a much higher toxicity threshold. Tabex is prescribed only to those patients who seriously decided to work on a complete cessation of smoking.

Persons with a smoker's experience of more than 40 years are prescribed the drug only after an interview with a doctor.

Clinical and pharmacological group

The drug for the treatment of nicotine addiction.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Tabex cost in pharmacies? The average price in 2018 is at the level of950 rubles.

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Composition and form of release

Medicinal form Tabexa - tablets: covered with a film membrane of brown color, round biconcave; At the break - from white to beige (50 pcs. in blisters, 2 blisters in a cardboard insert with a calendar of admission in a pack of cardboard; 20 pieces each. in blisters, in a cardboard bundle of 5 blisters).

• The active substance of the drug is cytisine: mg in 1 tablet.
• Auxiliary components: talc, magnesium stearate, microcrystalline cellulose and lactose monohydrate.

The composition of the film shell: Opadry II brown (lactose monohydrate, hypromellose (E464), macrogol 3000, titanium dioxide (E171), triacetin and iron dyes oxide yellow, iron oxide red and iron oxide the black).

pharmachologic effect

Active component Tabecs tablets is the alkaloid cytisine, which has holinomimeticheskim action. This compound increases blood pressure, activates the ganglion of the autonomic nervous system, promotes the development of adrenaline from the adrenal medulla, reflexively excites the respiratory Centre.

Despite the great similarity of the mechanisms of action of cytisine and nicotine, cytisine has a greater therapeutic index and is less toxic. As a competitor, cytisine suppresses the interaction of nicotine with receptors sensitive to it, which causes a gradual decrease and complete disappearance of nicotine (tobacco) dependence.

Indications for use

Tabex tablets are intended for oral administration to facilitate quitting in patients with severe nicotine addiction.

Contraindications

Absolute:

• Atherosclerosis;
• Pulmonary edema;
• Bronchial asthma;
• Bleeding from large vessels;
• Age to 18 and after age 65;
• Pregnancy;
• The period of breastfeeding;
• Galactosemia, lactase deficiency, glucose-galactose malabsorption syndrome (because lactose is included in the formulation);
• Recently suffered stroke (you can take Tabex no earlier than 1 month);
• Acute myocardial infarction;
• Heart arythmy;
• Severe hypertension;
• Unstable angina;
• Hypersensitivity to the components of the drug.

Relative (take the drug only after consulting a doctor):

• High blood pressure;
• Heart failure;
• Vasospastic and microvascular angina;
• Ischemic heart disease (stable angina, asymptomatic myocardial ischemia),
• Obliterating arterial diseases;
• Diseases of cerebral vessels;
• Stomach ulcer;
• Gastroesophageal reflux disease;
• Renal or hepatic insufficiency;
• Chromaffin tumors of the adrenal glands;
• Diabetes;
• Hyperthyroidism;
• Some forms of schizophrenia;
• Long-term experience of smoking in people older than 40-45 years.

Intended use for pregnancy and lactation

It is not recommended to use the drug during pregnancy, since there is a risk of embryotoxic effects. Also, Tabex is not prescribed to women during lactation.

Dosage and route of administration

As indicated in the instructions for the use of tablets Tabex are taken internally, squeezed with enough liquid. Do not exceed recommended doses. It is advisable to start taking the drug after the patient has been placed on a complete cessation of smoking.

The drug should be used according to the following scheme: from 1 to 3 days - 1 tablet 6 times / day every 2 hours, gradually reducing the number of cigarettes smoked.

The tablet should be taken between episodes of smoking to extend the intervals between cigarette smoking in order to minimize their consumption. The interval of reception every 2 hours should be observed. If you can not achieve a decrease in daily cigarette consumption, treatment should be discontinued and after 2-3 months you can start it again.

With a good effect, the treatment is continued according to the following scheme:

• from 4 to 12 days of administration - 1 tablet 5 times / day, every 2.5 hours;
• from 13 to 16 days - 1 tablet 4 times / day, every 3 hours;
• from 17 to 20 day - 1 tablet 3 times / day, every 5 hours;
• from 21 to 25 days - 1-2 tablets per day.

It is strongly recommended that you quit smoking no later than 5 days after the start of treatment.

Combination of drug therapy with consultations, incl. with measures of psychological support of the patient, significantly increases the effectiveness of treatment.

Side effect

Side-effects against the background of the reception of Tabex are:

• headache;
• dyspnea;
• abdominal pain;
• drowsiness or insomnia;
• constipation or diarrhea;
• a feeling of palpitations;
• irritability;
• increased blood pressure;
• nausea;
• increased sweating;
• pain in the muscles;
• tachycardia;
• dizziness;
• dryness in the oral cavity;
• decreased body weight;
• violation of taste perception;
• pain in the chest;
• decreased appetite.

Overdose

Taking an increased dose of Tabex (more than 6 tablets per day) can cause an overdose of the drug. This is a rather dangerous condition, accompanied by general weakness, vomiting, nausea, palpitations. The patient is pale, his pupils are dilated. In the absence of treatment, convulsions appear, and then - paralysis of the respiratory muscles, leading to death.

Therefore, in case of an overdose, or even only if there is a suspicion of an overdose of Tabex, you must immediately call an ambulance. Treatment is carried out in a hospital and consists of gastric lavage, intravenous drip administration of water-salt solutions, glucose solutions, anticonvulsants, and others.

special instructions

Before starting treatment, read the special instructions:

1. When using the drug, do not exceed recommended doses.
2. The drug should be used only if the patient has a serious intention to quit smoking.
3. Persons with a long history of smoking and those older than 40-45 years of age should take Tabecs only after consulting a doctor.
4. Treatment with the drug and continued smoking can lead to increased side effects of nicotine (nicotine intoxication).
5. The preparation contains an auxiliary substance lactose. Patients with rare hereditary problems of galactose intolerance, with lactase deficiency (Lapp) or glucose-galactose malabsorption should not be used Tabex.

Interaction with other drugs

When prescribing the drug, it is necessary to take into account interactions with other drugs:

1. After smoking cessation, the side effects of theophylline, ropinirole, clozapine and olanzapine may be exacerbated.
2. The simultaneous use of the drug Tabex with antihypertensive drugs (propranolol, etc.) can weaken their effect.
3. The use of the drug Tabex simultaneously with lovastatin, simvastatin, fluvastatin, pravastatin, and others. increases the risk of pain in the muscles.
4. With the simultaneous use of the drug Tabex with acetylcholine, carbachol, galantamine, pyridostigmine, rivastigmine, distigmine possibly increased cholinomimetic side effects (salivation, lacrimation, bronchial secretion with a cough and risk asthma attack, pupil narrowing, colic, nausea, vomiting, frequent urination, increased muscle tone or sudden muscle contraction).

Tabex - reviews of smokers

We offer you to familiarize yourself with some of the opinions of people who took Tabeks from smoking:

1. Olga. Now I do not smoke, I threw six months ago with the help of Tabex. Threw it can be said without difficulty, I only wanted to smoke for the first 2-3 days, then how it was cut off, and now even the smell of smoke causes terrible disgust.
2. Elena. She smoked for 19 years, twice tried to throw herself without aids from smoking. Has bought or purchased a tabex 07.12.16. I started to drink, from the side, there was an excessive palpitation, I drank 20 days. It's now 14.01.17. I do not smoke until I took a pill and did not even think about cigarettes, now I remember, especially when it's troublesome. Tabex helps, the main thing for yourself is to decide that you will not smoke. Drink plenty of water when you want to smoke.
3. Leonid. I have been smoking for 19 years. Tried to throw itself 100 and 1 time and all is useless, any nervyk and again again it is healthy. I decided to try with a tabex, while I do not smoke the second day. True, I decided to abandon cigarettes from the first day, and not from the fifth as in the instructions. Thrust of course there is, but not so much, from the smoke turns. When not at all in the mogot drink a soothing tea and eat peppermint candy without sugar, fresh breath))) well, I reread the rooms of those who have already given up)) and the program on the phone. put that my achievements schiaet and so on)) while holding on))) later I'll write what so how. Tabex helps)
4. Anna. Smoking is evil. Everybody knows about this, but for some reason they continue to smoke ((I was not an exception, until my health began to fall apart. Always thought that others were ill, but not me. Fortunately, I found the strength to give up, let not myself, but with a tabex, but left. It took 5 days to overcome the long-term habit and several more years of recovering the undermined health. Unfortunately, the consequences of my smoking affected even my child. Now I understand how stupid it was to smoke.

In general, most former smokers in 2018 claim that Tabex helped them effectively and within a short time to get rid of nicotine addiction. However, applying it in the presence of contraindications is strictly not recommended.

Analogues

The drug Tabex has no direct analogues in the market of pharmaceuticals. Among the most popular indirect analogues, not inferior to the original agent in therapeutic effectiveness, are:

1. Champion. The medicinal preparation Chepiks contains in the composition varenicline tartrate. Produced in the form of tablets coated with a film membrane. It is an extremely effective drug for fighting smoking and nicotine addiction. It can have a negative impact on the patient's psychoemotional state.
2. Nikvitin. Means Nikvitin as well as Nicorette contains in the composition of nicotine. The main difference is the presence of only one dosage form in the form of transdermal patches. To achieve the maximum therapeutic effect, it is recommended to combine wearing a patch with attending behavioral support activities.
3. Nicorette. Nicorette contains nicotine. Produced in the form of a transdermal patch, chewing gum with mint and fruit taste, and mint flavored lozenges. It is used for quitting smoking and treating nicotine addiction. With a significant overdose of the drug (30-60 mg of nicotine), it is possible to develop severe poisoning with a fatal outcome.

Before buying an analogue, consult your doctor.

Champix or Tabex - which is better?

Receiving Champix creates in the body reactions that are similar to those that occur during smoking. In this drug is similar to Tabex. But varenicline (active ingredient Champix) and nicotine are antagonists, i.e. warring substances. Therefore, if the person taking Champix, will light a cigarette - he appears to her strong disgust.

This is often accompanied by side effects:

• nausea;
• increased blood pressure;
• headache;
• insomnia or drowsiness;
• fast fatiguability;
• excessive irritability.

However, despite the abundance of side effects, experts consider Champix to be more modern, more effective and more potent drug than Tabex. The medicine is more expensive: on average, the price of Champix varies from 1000 to 3000 rubles. The course of treatment lasts 12 weeks.

Shelf life and storage conditions

Tabex should be stored in a dry place inaccessible to children and light at a temperature not exceeding 25 ° C.

Shelf life - 2 years.

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