Rengalin

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width = Rengalin - a complex antitussive homeopathic drug, which has anti-inflammatory, analgesic, anti-allergic effect.

This is a relatively inexpensive preparation of domestic production, which is widely prescribed not only for the treatment of adult patients, but also in pediatrics. Rengalin is often included in the treatment scheme of various pathologies of the lungs and bronchi accompanied by a cough.

The production of the drug is handled by the Russian pharmaceutical company Materia Medica Holding. The drug is released in the form of tablets and a solution for oral administration (syrup).

Clinical and pharmacological group

Antitussive, anti-inflammatory drug with anti-bronchoconstrictive action.

Terms of sale from pharmacies

You can buy without a doctor's prescription.

Price

How much does Rengalin cost in pharmacies? The average price is at the level of180 rubles.

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Composition and form of release

The medicine is produced in two, different in consistency, forms:

  1. Rengalin tablets for resorption of 20, 10 and 50 pieces in one carton. The tablets themselves are presented in a flat-cylindrical form and almost white, and on one side there is an inscription of the preparation in Latin letters - "RENGALIN".
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  2. 100 ml-th transparent solution containing 120 mg of antibodies against morphine, bradykinin and histamine. It is allowed to children from three years old.

Active ingredients in 1 tablet:

  • affinity purified antibodies to morphine - 6 mg *;
  • affinity purified antibodies to histamine - 6 mg *;
  • affinity purified antibodies to bradykinin - 6 mg *.

* - substances which, in the form of a combination of three active aqueous-alcoholic dilutions of the substance (in 10012, 10030, 10050 times) are applied to isomalt.

Active ingredients in a 100 ml solution:

  • affinity purified antibodies to morphine - 120 mg **;
  • affinity purified antibodies to histamine - 120 mg **;
  • affinity purified antibodies to bradykinin - 120 mg **.

** - substances introduced into the solution as a mixture of three active aqueous dilutions of the substance (in 10012, 10030, 10050 times).

Auxiliary ingredients, depending on the dosage form:

  • tablets: isomalt, microcrystalline cellulose, citric anhydrous acid, magnesium stearate, sodium saccharin, sodium cyclamate, colloidal silicon dioxide;
  • solution: purified water, citric anhydrous acid, potassium sorbate, glycerol, maltitol.

pharmachologic effect

It has been shown experimentally that the components of the preparation modify the activity of the ligand-receptor interaction of endogenous regulators with corresponding receptors: antibodies to morphine - with opiate receptors; antibodies to histamine - with histamine H1 receptors; antibodies to bradykinin - with B1 receptors of bradykinin; while the combined use of components leads to an increase in the antitussive effect.

In addition to the antitussive effect, the complex drug due to its components has anti-inflammatory, anti-edematous, antiallergic, spasmolytic (antibodies to histamine, antibodies to bradykinin) and analgesic action (antibodies to morphine).

Complex preparation of Rengalin due to modification of histamine-dependent activation of H1 receptors and bradykinin-dependent activation of B2 receptors selectively reduces the excitability of the cough center of the medulla oblongata, inhibits the central links of the cough reflex. Inhibiting the centers of pain sensitivity in the thalamus, blocks transmission of pain impulses to the cerebral cortex. Inhibits the flow of painful impulses from the periphery due to a decrease in the release of tissue and plasma algogens (histamine, bradykinin, prostaglandins and others). Unlike narcotic analgesics does not cause respiratory depression, drug dependence, does not possess narcogenic and hypnotic effects.

It alleviates the manifestations of acute pharyngitis, laryngitis and bronchitis, reducing bronchospasm. It relieves systemic and local symptoms of allergic reactions by influencing the synthesis and release of histamine and bradykinin from mast cells.

Indications for use

In the medicine Rengalin from cough, the instruction contains such information regarding the indications:

  1. Chronic pathology of the bronchopulmonary system, accompanied by a cough of a different nature. It can be cystic fibrosis, congenital lobar emphysema, bronchiectasis, etc.
  2. Bronchial asthma, manifestations of which are attacks of suffocation, dyspnoea and cough with hard-to-separate sputum. In this case, the drug will affect all links of the pathogenesis of the disease.
  3. ORI of a viral genesis, taking place with a productive and dry cough. In this case, the intensity of the cough reflex decreases and the exudative component of inflammation decreases, which accelerates the further recovery.
  4. Acute obstructive bronchitis, acute laryngitis and acute pharyngitis of bacterial nature. With these diseases, there is a moist and non-productive cough.
  5. Chronical bronchitis. Characterized by a wave-like current and a low-yielding cough with stiff sputum.

Contraindications

  • hereditary intolerance to fructose (for solution);
  • individual intolerance of the components contained in the preparation.

Children Rengalin contraindicated before the age of 3 years.

Conditions / diseases in which Rengalin from a cough is prescribed with caution:

  • diabetes mellitus (for solution);
  • pregnancy;
  • lactation period.

Intended use for pregnancy and lactation

It is important that at the moment the medicine does not have information on whether it is possible women in the position or in the process of feeding the baby to perform direct treatment of this kind drug. At least until now, no drug studies have been conducted.

That's why only a doctor can prescribe this treatment, which, through the use of general health data, mother, and child (fetus) will come to the conclusion that the drug will not bring any threat and besides it will be enough effective.

Dosage and route of administration

As indicated in the instructions for use, Rengaline tablets are kept in the mouth until completely dissolved, regardless of food.

The recommended dose is 1-2 pcs. 3 times a day, with the possible increase in the frequency of reception up to 4-6 times a day in the first 3 days of therapy (depending on the severity of the patient's condition).

The duration of therapy is determined by the doctor depending on the severity of the pathology.

Solution for oral administration

The solution is taken orally regardless of food.

The recommended dose is 5-10 ml (1-2 h. l.) 3 times a day. Multiplicity of drug intake in the first 3 days of treatment can be increased up to 4-6 times a day, depending on the severity of the patient's condition.

The duration of the course of treatment is set by the doctor individually for each patient, depending on the severity of the disease.

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Side effect

During the period of application of Rengalin from cough, development of reactions of increased individual sensitivity can be observed.

Overdose

In case of accidental significant excess of the recommended therapeutic dosage of tablets for resorption of Rengalin, dyspeptic phenomena in the form of nausea and vomiting may develop. In this case, the drug should be discontinued and seek medical attention.

special instructions

Rhenol in the form of tablets does not affect the ability to drive vehicles and work with other mechanisms that carry a potential danger.

Use the drug in the form of a solution diabetic patients with caution. It should be remembered that in each teaspoon of the drug (5 ml) contains, g of maltitol. This figure corresponds to 2 XE. To the body could perform the metabolism of the substance, you need insulin. However, due to slow hydrolysis and absorption in the gastrointestinal tract, the need for insulin is negligible.

The energy value of maltitol is 10 kJ, which corresponds to kcal / g. This indicator is much lower than similar parameters, is inherent in sucrose. By computing, one can find out that one teaspoon of Rengalin in the form of a syrup contains approximately, kJ or 7 kcal.

The specialists did not study the influence of Rengalin in the form of a syrup on the ability to drive vehicles or dangerous mechanisms.

Interaction with other drugs

As for interaction with other medicines, at the moment there is no information that would be confirmed by clinical studies on their incompatibility with Rengalin. Regardless of whether the agent has a similar pharmacological effect or belongs to another group of drugs, a joint application with these tablets or syrup is not prohibited.

Rengalin is very suitable for children as a complex therapy. It does not enhance or weaken the effects of concomitant medications, does not affect their metabolism and excretion of the body.

Reviews

We offer you to get acquainted with the reviews of people who used the drug Rengalin from cough:

  1. Anna. I gave Rengalin tablets while treating my son's wet cough. The drug was prescribed to us by a doctor. It was an ordinary cold, but only the sputum bleached badly because of its high viscosity. Thanks to the medication under consideration, it was much easier for the little son on day 3. He can already fully play, do his own things, and most importantly, that the nights began to pass him calmly
  2. Danila. Tortured with a cough 3 weeks. It happens that a couple, three days feel great, and on the 4th takes a cough. I decided to buy a cough medicine, Rengalin was advised in a drugstore in tablets. Gradually, breaks between coughing episodes decreased, and then completely cough passed.
  3. Catherine. I used the drug Rengalin in the treatment of a cough that arose on the background of bronchitis. The matter is that he at me 3 years, as chronic, so several times a year I have to treat a debilitating dry cough. But now I know what to do when the first symptoms of the disease have arisen. I buy a tablet preparation of Rengalin and take it according to the dosage prescribed by the doctor. Thanks to the complex effect of the drug and the fact that I reacted quickly, I managed to cope with unpleasant symptoms and dry cough for a week.

Analogues

Among the main analogs of this tool are:

  1. Kodelak-Fito. Another solution, based on components of exclusively plant origin. An expectorant effect and a decrease in the severity of cough is achieved by suppressing the cough center and reducing the secretion in the bronchi.
  2. Broncholitin. Combined means. Has bronchoantiseptic and bronchodilating effects. Glaucin, present in the composition, depresses the cough and respiratory centers, which helps to quickly cope with the problem.
  3. Neo-Codion. Reduces cough. The main active ingredient is camphosulfonate. However, its cost is twice as high.
  4. Bronchicum. Syrup, providing an expectorant effect, relieves pain in the nasopharynx and throat, reduces the cough reflex. Refers to phytopreparations, the main components of which are menthol and thyme extract. Often appointed in conjunction with Rengalin. For the price of the funds are approximately the same.
  5. Glycodine. Refers to the group of mucolytic drugs. Effectively and quickly heals a cough of a different nature.
  6. Bronchocin. Complex effects on the respiratory and nervous systems, providing an antitussive effect.
  7. Co -anol. It is characterized by an expectorant, antiallergic and antitussive action. Anesthetizes, relieves spasms and stops inflammation.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The shelf life of the Rengalin resorption tablets is 3 years. The drug should be stored only in its original packaging, in a dark, dry place inaccessible to children at an air temperature of no more than + 25 ° C.


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