Arkoksia is a medicinal product that belongs to the group of combining agents.
The drug has the properties of an analgesic, antipyretic and anti-inflammatory agent. The drug is an advanced second-generation inhibitor. Assign a drug to relieve acute symptoms of osteoarthritis, rheumatoid arthritis.
On this page you will find all information about Arkoksia: the full instruction on the application to this medicinal medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Arkoksia. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
NSAIDs.
Conditions of leave from pharmacies
Released without a doctor's prescription.
Price list
How much does Arkoksia cost? The average price in pharmacies is at the level of420 rubles.
.Form of issue and composition
The active substance of the drug is etorikoksib.
The drug is available in the form of tablets intended for oral administration. The quantitative content of the active component Arkoksia: 60, 90, 120 mg. Auxiliary elements are: lactose, cellulose, magnesium stearate, titanium dioxide, aluminum dye based on dyes.
Pharmacological effect
An anti-inflammatory drug of a non-steroidal group, which blocks the synthesis of prostaglandins and thus has an anti-inflammatory, antipyretic and analgesic effect.
Indications for use
In what cases is it expedient to take the medicine "Arkoksia"? Its application is wide enough, as it provides a quick analgesic effect, and also allows to eliminate the inflammatory process.
Nevertheless, most often the drug is prescribed to patients suffering from osteoarthritis and rheumatoid arthritis. Indications for use are also pain caused by gouty arthritis and ankylosing spondylitis. In some cases, pills are recommended for people who have recently undergone a dental operation.
Contraindications
Before using this drug, you should go to the doctor and find out if there are any contraindications for the use of Arkoksia. According to scientific research there are a number of contraindications:
- tendency to bleeding GIT;
- cerebrovascular bleeding;
- individual intolerance of the constituents of the drug;
- bronchial asthma;
- polyposis of the nose or sinuses in the stage of exacerbation and frequent relapses;
- intolerance to NSAIDs;
- ulcers, erosion and perforation of the gastrointestinal tract;
- inflammation of the intestine;
- kidney disease in progress;
- hyperkalemia;
- blood disorders due to clotting disorder (hemophilia);
- hepatic insufficiency in severe form;
- hepatic diseases;
- CRF;
- pregnancy and breastfeeding;
- children under 16;
- period after surgery associated with aortocoronary bypass surgery;
- diseases of peripheral arteries;
- arterial pressure over 140/90 Hg;
- cerebrovascular diseases;
- lactase intolerance, lactase deficiency.
Application in pregnancy and lactation
The drug is contraindicated in pregnancy and lactation.
The use of the drug may adversely affect female fertility and is not recommended for women planning pregnancy.
Instructions for use Arkoksia
The instructions for use indicate that the tablets of Arkoksia are taken orally at a dose of 60-120 mg 1 time / day.
In patients with hepatic insufficiency (5-9 points on the Child-Pugh scale), it is recommended not to exceed the daily dose of 60 mg.
Side effects
When using the drug Arkoksia there is a possibility of unwanted side effects.
- Organs of the senses: impaired vision.
- Nervous system: on the background of taking Arkoksia, dizziness, headache, weakness are often observed. In rare cases, patients can complain about the development of anxiety, drowsiness, sleep disorders and hypersensitivity.
- Gastrointestinal tract: development of nausea, diarrhea, dyspepsia, flatulence. With prolonged use of the drug Arkoksia, the likelihood of side effects from the gastrointestinal tract increases.
- Musculoskeletal system: in rare cases, Arkoksia can provoke cramps, arthralgia or myalgia.
- Skin: In some cases, there may be swelling of the face and itching of the skin.
- Cardiovascular system: heart palpitations, increased blood pressure. In rare cases, the use of Arkoksia can cause congestive heart failure, hot flashes and cerebral circulation disorders.
- Development of infections: in a number of cases, the development of gastroenteritis, as well as infections of the upper respiratory tract and urogenital system was recorded.
According to the results of laboratory studies, in rare cases there is a possibility of increasing nitrogen in urine and blood, as well as a decrease in the level of hemoglobin.
Overdose
Overdose Arkoksia was not described. It is possible to increase the side effect of the drug, for the treatment of which symptomatic treatment is performed.
special instructions
- Caution should be given to patients taking other non-steroidal anti-inflammatory drugs, especially acetylsalicylic acid;
- When prescribing the drug, perforation, ulceration or bleeding from the upper parts of the digestive tract is possible, up to a lethal outcome;
- There should be careful monitoring of kidney function in persons prone to impairment of their function, since etorikoksib can reduce renal blood flow;
- In the presence of pathology on the part of the heart or vessels, it is necessary to prescribe the drug in short courses and in the lowest effective dosage, since the use of etorikoksib possible development of thrombotic complications;
- With possible pathologies of the liver, it is necessary to control the level of transaminases in the blood;
- Particular attention should be paid to elderly people, if there is a violation of the function of any of the body systems, if there is dehydration in the patient;
- Be wary when taking warfarin and other oral anticoagulants;
- Etorikoksib is not recommended for use in planning pregnancy;
- Serious skin lesions manifested itself in isolated cases. Anaphylactic reactions and development of Quincke edema are possible, due to which attention should be paid to the presence of allergic reactions in the patient's history to any medication. When the first skin manifestations appear, the medicine should be discarded;
- And the composition of Arkoksia includes lactose, as a result of which the drug is contraindicated for persons suffering from its intolerance;
- When taking medication, fluid retention in the body, development of edema and arterial hypertension is possible. Therefore, when prescribing a drug for patients with a tendency to such phenomena, it is necessary to observe precautions, pay special attention to control of blood pressure, and in case of deterioration, take appropriate measures until the drug is discontinued and an alternative treatment.
Drug Interactions
- Increase the risk of developing nephrotic admission with cyclosporine and tacrolimus.
- Simultaneous reception with teotreksatom enhances its side effects.
- Simultaneous reception with rifampicin reduces by 65% AUC in plasma etorikoksiba.
- With joint admission even in low doses, ASA leads to an increased risk of ulcerative gastrointestinal lesions.
- This drug may somewhat weaken the hypotensive effect of FGA inhibitors.
- Admission along with antacids and ketoconazole had no significant effect on the formokinetics of Arkoxia.
- Joint reception with oral contraceptives and a dose of Atcoxia 120 mg.- increases the development of thromboembolic complications.
- Joint intake of the drug in a higher dose (120 mg) with warfarin increases INR by 13%. This indicator should be monitored when changing the dose and at the beginning of therapy. If there is a violation of kidney function, simultaneous administration with inhibitors of APT aggravates the functional deficiency of the kidneys.
Reviews
We picked up some feedback from people about the drug Arkoksia:
- Svetlana. Propyl only 4 tablets 90 mg. The pressure was already on the second day, and after taking 4 tablets, spasms appeared in the stomach. True pain in the knee and remained. While decided to stop taking this drug. Who can answer, do not drink it at all.
- Elena. The girl gave Arkoksila 90 mg tablets. Today the first night slept in the last month. Pulled the ligaments in the foot, the pain unbearable for a month. And then I got up in the morning and went quietly as if nothing had happened, but without pain. I was the first pill to relieve prolonged pain.
Most patients note a rapid therapeutic effect and high effectiveness in the treatment of the drug, but there are those who have not benefited from the drug Arkoxia. Doctors associate such a difference in treatment with individual characteristics and the general health of the patient.
Analogues
Analogues in composition Arkoksia has not. On the therapeutic effect, the most popular are the substitutes:
- Alflutop (nyxes) - the average price is from 1800 rubles;
- Dona - the average price is from 1700 rubles;
- Rumalon - the average price of 1900 rubles.
Among the cheap there are the following analogues of Arkoksia:
- Diclofenac - from 30 rubles;
- Indomethacin - from 60 rubles;
- Piroxicam - from 95 rubles;
- Cefekon - from 130 rubles;
- Nimesan - from 130 rubles.
Before using analogues, consult your doctor.
Storage conditions and shelf life
Store at temperatures below 30 degrees. Keep away from children. Shelf life is three years. Do not use after the expiration date.
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