Valsartan tablets (40, 80 and 160 mg): instructions and reviews

Valsartan belongs to the group of intermediates with a pronounced effect of intigipertenziveness.

The active substance of the drug is valsartan, which effectively fights hypertension of the arterial type. The drug acts on the cellular level on the area responsible for the increased pressure

On this page you will find all information about Valsartan: full instructions for use on this medicated medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Valsartan. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antihypertensive agent.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Valsartan cost? The average price in pharmacies is at the level of165 rubles.

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Form of issue and composition

The medicine is sold in pharmacies in the form of powder, capsules, granules and tablets.

• The preparation containsvalsartanas an active ingredient.

Tablets of 40 mg include the following additional components: magnesium stearate, croscarmellose sodium, microcrystalline cellulose, dye "Opadrai pink".

Tablets of 80 and 160 mg contain the following auxiliary elements: croscarmellose sodium, magnesium stearate, dye "Opadrai pink microcrystalline cellulose, aerosil

Pharmacological effect

The active substance of the drug provokes a competitive blocking of the AT1 angiotensin II receptors, which are in the vascular endothelium, cardiac muscle, adrenal cortex, renal tissue, brain and pulmonary tissue. This leads to inhibition of angiotensin effects. The drug reduces myocardial hypertrophy in hypertension.

• After a single application, the effect is noticeable after 120 minutes, it lasts throughout the day. A strong therapeutic effect is achieved 3 weeks after the first day of the course.

In people with CHF, the drug eliminates hyperstimulation of RAAS, prevents pathological proliferation of cells, reduces swelling. Its reception reduces preload and increases cardiac output.

Indications for use

The drug valsartan is prescribed for heart failure and chronic low blood pressure (hereinafter - AD). The drug can be used after myocardial infarction. In their group (sartan), these are the only pills that can not negatively affect the condition and vital activity of the body after a heart attack.

Valsartan tablets are used by those who have been drinking digitalis, diuretics, beta-blockers or inhibitors.

Contraindications

Valsartan is not prescribed for:

• evidence in pediatrics;
• severe violations of the liver;
• hypersensitivity to valsartan, auxiliary components of tablets;
• pregnancy;
• lactation.

With care, Valsartan tablets are prescribed for:

• hyponatrial diet;
• bile duct obstruction;
• stenosis of the renal arteries;
• dehydration;
• renal failure (severe).

Application in pregnancy and lactation

Valsartan tablets are not prescribed for the treatment of pregnant women because of the danger to the fetus. If the woman took the drug and during this period became pregnant, it should be stopped as soon as possible and go to the doctor, in some cases, the pregnancy has to be interrupted.

Use of this medication during breastfeeding is prohibited because of the large the probability of penetration of active ingredients into breast milk, and then into the body child. If it is necessary to treat Valsartan, a lactating woman will have to stop lactation.

Instructions for use

In the instructions for use, it is indicated that you should take oral valsartan tablets. Tablets are not recommended to chew.

With arterial hypertension, the standard daily dosing corresponds to 80 mg of valsartan. Increase in dosage is carried out only with insufficient therapeutic efficiency. The maximum daily dose is 640 mg. To achieve the required dose, the increase in daily dosing is carried out gradually.

After a heart attack, it is prescribed at 40 mg / day in the initial hours, then gradually increase for 3 months to 320 mg / day. With the observed hypotension, the patient is reduced dosages.

Side effects

Taking this medication can cause some undesirable effects:

1. Exchange processes: increase in the concentration of potassium ions;
2. Respiratory system: the appearance of cough, inflammation of the pharynx;
3. The immune system: increased risk of developing viral infections;
4. The cardiovascular system: lowering the level of blood pressure;
5. Digestive system: increased level of bilirubin concentration, indigestion;
6. central nervous system: headaches, dizziness, fatigue, general weakness;
7. Hematopoietic system: a decrease in hemoglobin, a decrease in the number of neutrophils, a decrease in the total number of blood cells;
8. urinary system: functional disorders of kidneys, increased levels of urea nitrogen, increased levels of creatinine;
9. Hypersensitivity reactions to Valsartan: skin rash, serum sickness, Quincke's edema, itchy skin, inflammation of blood vessels.

Overdose

Symptoms of overdose - hypotension, bradycardia, tachycardia. The treatment is symptomatic. Dialysis is not effective.

special instructions

1. With extreme caution apply in patients with violations of patency of the biliary tract.
2. In patients with renovascular hypertension, which developed again due to stenosis of the renal artery, the level of urea and creatinine in the serum should be regularly monitored during the treatment period. Data on safety of use in patients with SC less than 10 ml / min are absent.
3. In cases of hyponatremia and / or a decrease in bcc, as well as against the background of therapy with high doses of diuretics, in rare cases valsartan can cause severe arterial hypotension. Before the start of treatment should be done correction of water-salt metabolism.
4. Due to the inhibition of RAAS in susceptible patients, changes in renal function are possible. With the use of ACE inhibitors and angiotensin receptor antagonists in patients with chronic heart failure severe oliguria and / or augmentation of azotemia, rarely developed acute renal failure with a risk of lethal outcome.

Drug Interactions

With the simultaneous use of Valsartan:

• atenolol, warfarin, cimetidine, furosemide, digoxin, indomethacin, amlodipine, hydrochlorothiazide, glibenclamide do not cause clinically significant interaction;
• remedies acting on the renin-angiotensin-aldosterone system (RAAS) the incidence of renal dysfunction, arterial hypotension, and hyperkalemia, compared with monotherapy;
• lithium preparations intensify their toxic effects, increasing the lithium content in blood plasma;
• Non-steroidal anti-inflammatory drugs, including selective inhibitors of cyclooxygenase-2, can lower antihypertensive effect of valsartan, cause an increase in potassium levels in the blood plasma and impairment of function kidney;
• rifampicin, cyclosporine, ritonavir may increase the concentration of valsartan in the serum;
• potassium preparations, potassium-sparing diuretics (including amiloride, spironolactone, triamterene), potassium-containing salts can to increase the level of potassium concentration in the blood serum, and in case of cardiac insufficiency - the creatinine content in blood serum.

Reviews

We picked up some reviews of people about the drug Valsartan:

1. Maksim. Took different medications for 5 years, many did not help, the doctor attributed vampire 10/160 today 5 day of taking the pressure really keeps the day and the heart does not hurt, but so far there are unpleasant symptoms
2. Galina. Today, appointed valsarta, we drank amladipit, I'm 64 years old. The pressure became jumping. I do not know how to fit. We in turn tried different medications, starting from the most expensive at , 00 per package and everywhere there were pobochki as written in the indications. let's hope that this drug will help.
3. Valentine. Very effective antihypertensive drug of the last generation. Well suited to young patients suffering from hypertension. Alas, with our ecology and way of life, such people are not uncommon. The main positive feature of this drug is the absence of a negative effect on sexual function. After all, the peasant in the prime of his life to poison himself with pills for the sake of reducing the pressure oh like a reluctance. That's why I recommend it to all my friends who have problems with pressure.

Analogues

The most common analogues of Valsartan for today are the following medications:

• "Valaar
• "WALZ
• "Valsartan A
• Valsartan N;
• "Nortivan
• "Diovan
• "Valsakor
• Valsartan Zentiva;
• Artinova;
• "Valsartan Granulate
• Valsafors;
• Valsasin;
• "Valsakor
• "Tareg
• Tontordio.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Shelf life of the tablets is 3 years from the date of production, which is indicated on the packaging. The drug should be stored out of reach of children at a temperature of not more than 30 degrees.

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