Erespal

Erespal is a medicinal product belonging to the group of H1-antihistamines. It has antihistaminic, antispasmodic, and anti-inflammatory effect.

Anti-inflammatory and anti-bronchoconstrictive activity of fenspiride is caused by a decrease in the production of a number of biologically active substances (cytokines (especially TNFα), arachidonic acid derivatives, free radicals) that play an important role in the development of inflammation and bronchospasm.

Inhibition of fenspiride metabolism of arachidonic acid is potentiated by blockade of histamine H1-receptors, tk. histamine stimulates the metabolism of arachidonic acid, the formation of prostaglandins and leukotrienes. Fenspiride blocks α-adrenoreceptors, stimulation of which is accompanied by an increase in the secretion of bronchial glands.

Thus, fenspiride reduces the effect of a number of factors that contribute to the hypersecretion of pro-inflammatory factors, the development of inflammation and bronchial obstruction. Fenspiride also has an antispasmodic effect.

Clinical and pharmacological group

Anti-inflammatory, anti-bronchoconstrictive drug.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much does Erespal syrup in pharmacies cost? The average price is at the level of300 rubles.

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Composition and form of release

The drug is produced in two varieties: syrup and tablets.

1. Syrup Erespal - a destructive form of the drug, it is released in bottles of dark glass, volume 150ml. The medicine has a pleasant orange color, a viscous consistency, a smell and taste of honey. In 1 ml of syrup contains 2 mg of active substance fenspirida and a number of auxiliary components (extracts of rose, orange, licorice root, vanilla, rum, honey). Vials are additionally packed in cardboard boxes, each of which has a liner with instruction.
2. Tablets Erespal 80 mg - round, smooth, with protuberances to the sides, in a film shell. They are packed in blisters, 15 washers per each. The package contains two blisters (30 tablets) and a detailed annotation to the preparation, describing its properties and recommended use.

The active component of the drug is fenspiride hydrochloride. In addition to this substance, which has a direct therapeutic effect, the preparation contains auxiliary components that promote faster absorption of the drug, and accordingly, a faster curative effect.

Pharmacological effect

The anti-inflammatory effect of the drug is based on the activity of fenspiride, which is part of its composition. This component provides a reduction in the production of certain biologically active substances, mainly free radicals and cytokines that are directly involved in the development of inflammation and bronchospasm.

Fenspiride also promotes the blocking of alpha-adrenergic receptors, the activation of which increases the secretion of bronchial glands.

Thus, the main active component of the drug prevents the development of inflammation and obstruction of the bronchi, and also contributes to spasmolytic activity.

Indications for use

Below are the main indications for the use of this drug in childhood:

1. laryngitis;
2. bronchitis in various stages of development;
3. tracheobronchitis;
4. asthmatic conditions (in the course of complex therapy);
5. a hoarse voice and cough that disturbs the child in case of influenza or measles;
6. infectious diseases of respiratory organs accompanied by cough;
7. otitis, sinusitis.

Contraindications

According to the instructions, Erespal does not apply:

• under 2 years of age (syrup);
• under the age of 18 (tablets);
• if there is an increased sensitivity of the patient to the main substance of the drug and its other components.

Syrup Erespal, due to the presence of sucrose in it, is cautiously prescribed to people with diabetes mellitus, glucose / galactose malabsorption syndrome, fructose intolerance, sugarase / isomaltase deficiency.

Intended use for pregnancy and lactation

The use of Erespal in pregnancy and lactation is not recommended because of limited clinical safety data for these categories of individuals. Nevertheless, therapy with Erespal and analogues in the period of gestation is not grounds for the artificial termination of pregnancy.

Dosage and route of administration

As indicated in the instructions for use, Eraspal syrup is taken orally, before eating. Before use, the syrup should be shaken.

Adults and teenagersthe drug is prescribed for 3-6 table spoons or 3-6 measuring cups, filled to 15 ml, which corresponds to 45-90 ml / day. The daily dose can be divided into several receptions (from 3 to 6).

Children from 2 years oldthe drug is prescribed at the rate of 4 mg / kg body weight / day.Children with body weight up to 10 kg- 2-4 teaspoons or 2-4 measuring cups, filled to 5 ml, which corresponds to 10-20 ml / day, can be added to a bottle with food. Children with a body weight of more than 10 kg - 2-4 tablespoons or 2-4 measuring cups, filled to 15 ml, which corresponds to 30-60 ml / day. The daily dose can be divided into several receptions (from 2 to 4).

• 1 tablespoon or 1 measuring cup, filled to 15 ml (15 ml of syrup), contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.
• 1 teaspoon or 1 measuring cup, filled to 5 ml (5 ml of syrup), contains 10 mg of fenspiride hydrochloride and 3 g of sucrose.

The duration of treatment is determined by the doctor.

Adverse Reactions

Against the background of the use of Erespal syrup, it is possible to develop negative reactions from various organs and systems:

1. Nervous system - drowsiness, periodic dizziness.
2. The digestive system - nausea, pain in the stomach, rarely can develop vomiting and diarrhea (diarrhea).
3. Skin and subcutaneous tissue - redness, less often a rash, itching of the skin, necrotic dermatitis with the death of a significant number of skin cells.
4. The cardiovascular system is a moderate increase in the frequency of cardiac contractions (tachycardia), a decrease in the level of systemic arterial pressure, the appearance of an unpleasant palpitation.

If there are signs of development of negative reactions against the background of taking Erespal syrup, you should consult a medical specialist.

Overdose Symptoms

When taking syrup or tablets at a dose of more than 2320 mg - immediately go to a medical facility. Symptoms: agitation or drowsiness, inhibition, nausea and vomiting, tachycardia with an accelerated sinus rhythm.

special instructions

Before you start using the drug, read the special instructions:

1. The composition of the drug includes parabens (parahydroxybenzoates), so that the use of this drug can provoke the development of allergic reactions, including. deferred.
2. When prescribing the drug for patients with diabetes it is necessary to take into account that Erespal Syrup contains sucrose (1 teaspoon or 1-dimensional a glass filled to 5 ml of syrup - 3 g of sucrose = 0.3 XE; 1 tablespoon or 1 measuring cup, filled to 15 ml of syrup - 9 g of sucrose = 0.9 XE).

Studies to study the effect of Erespal on the ability to drive vehicles and work with mechanisms have not been carried out. Patients should be aware of the possible development of drowsiness when taking Erespal, especially at the beginning of therapy or when combined with admission alcohol, and should be cautious when driving vehicles and performing work that requires a high speed of psychomotor reactions.

Compatibility with other drugs

Special studies on the interaction of fenspiride with other drugs have not been conducted.

Because of the possible increase in sedation with the administration of histamine H1 receptor blockers, the use of Erespal syrup in combination with drugs with sedative effect, or in combination with alcohol.

Patient Reviews

We offer to familiarize with reviews of people who used Erespal:

1. Raisa. Nuclear medicine. After taking one pill, my condition worsened. There was weakness in the legs, inhibition, a wonderful head, a pulse rose at night and in the morning, too, and nightmares also lasted all night. Today she called the doctor again. Do not buy this nuclear medicine.
2. Anya. Excellent medicine. Helps with inflammatory diseases of the throat, and with prolonged coughing too. To the child 3 years, we use already throughout 2 years at an ORVI and a laryngotracheitis. And in the hospital, by the way, he was also prescribed for bronchitis. Of course, you need to take not three days, but a full course, as the doctor will appoint.
3. Zinaida. Have appointed or nominated from a tracheobronchitis (a whistle, wheezing, exhausting cough). She drank 10 days for 1 tx3 times. All as a hand took off. Yes, palpitation (asparks under the tongue), the stomach got sick - oatmeal. Since this cough has very much tortured and it is impossible to fall asleep from wheezing. Shortness of breath was at least on the street do not go out. I choose the erespal!

Analogues

Structural analogs for the active substance:

• Fenspiride hydrochloride.

Before buying an analogue, consult your doctor.

Which is better: Erespal or Lazolvan?

Prescribe a drug for the treatment of an adult or a child should only be a doctor. Erespal more effectively reduces inflammation, and Lazolvan promotes liquefaction and sputum discharge. That is, Lazolvan is used for a damp cough. Often patients are also interested in whether it is possible to take Erespal and Lazolvan simultaneously. The compatibility of these medicines is acceptable. However, only the doctor can appoint Lazolvan and Erespal together, since a special scheme for taking these drugs is required.

Which is better: Erespal or Ascoril?

The drug Ascoril has in its composition three active substances - salbutamol, bromhexine, guaifenesin. It acts on the body as a broncholic, mucolytic. Erespal and Ascoril are simultaneously prescribed, only by a doctor according to the indications. The patient also can not independently answer that it is better - Erespal or Askollil, since it is necessary to take into account the diagnosis and individual characteristics of the patient.

Questions about combining Erespal with other cough medicines occur in people very often. For example, is it possible to take Erespal and Fluditik together? Is cough treatment treated in such a way that Erespal and ATSTS can be used together in one treatment regimen? Despite the fact that there are no strict instructions on the incompatibility of these drugs, alone, without consulting a doctor, you can not combine any funds from a cough.

Thus, before you answer, at what cough to take this or that drug, you need to carefully study the annotation and consult a doctor. At what cough appoint and drink a certain syrup or tablets, depends on its active substance and action on the body.

Shelf life and storage conditions

Shelf life of syrup for children Erespal is 3 years. It should be stored in its original packaging, dark, dry, inaccessible to children at an air temperature of no higher than 25 ° C.

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