Eye ointment Dexa-Gentamicin: indications for use and precautions

Eye ointment Dexa-Gentamycin is a synthetic medicinal formula of the combined type, which is actively used in modern ophthalmology. It consists of two active substances - antibiotic Gentamicin and GCS Dexamethasone, which provides the maximum effectiveness of the drug with a minimum of side effects (which occur when using the two indicated formulas for separately). Read more about the indications for use, contraindications, precautions and possible side effects.

Description of the preparation

Eye ointment Dexa-Gentamicin is a combined synthetic drug.It consists of two active substances - Gentamicin (antibiotic) and Dexamethasone (GCS). Compatibility of components is optimal, due to which the maximum therapeutic effect is achieved.

Dexa-Gentamicin is used in the treatment of inflammatory processes in the cornea of ​​the eye.

The drug Dexa-Gentamicin is available in two forms - eye drops and ointment.

Eye ointment is white with a yellow tinge. Its composition:

• dexamethasone 300 μg;
• gentamycin sulfate - 5 mg;
• petroleum jelly white;
• liquid paraffin;
• lanolin.

The delivery form is aluminum tubes with a volume of 2.5 g with a convenient polyethylene tip in a cardboard box. The maximum duration of treatment is 2-3 weeks.

Analogues among ointments: Erythromycin, Tetracycline, Floxal.

We recommend that you familiarize yourself with the instructions for the use of Phloxal ointment.

Erythromycin - analogue of Dexa-Gentamicin

The duration of Dex-Gentamicin treatment should not exceed 2-3 weeks.

Pharmacological action and group

Dexa-Gentamycin is a combined topical preparation providing sufficient dosage and full compatibility of both components.Pharmacological group - antibiotic soluble in water, related to aminoglycosides.The drug has a pronounced bactericidal action against a broad spectrum of both gram-positive and gram-negative bacteria. Through intact cornea, Gentamycin does not penetrate. Damage, inflammation in the cornea lead to the penetration of the active substance through the cornea of ​​the eye into its anterior chamber 15 minutes after instillation.

Dexa-Gentamicin has a pronounced bactericidal effect

With topical application of the drug, systemic absorption is low.

Dexamethasone is a synthetic, powerful GCS(glucocorticosteroid). Its anti-inflammatory and antiallergic effect exceeds the effect of cortisol (natural endogenous GCS) exceeds 25 times. Dexamethasone can penetrate through the cornea with intact epithelium into the tear fluid of the anterior chamber of the eye.

Indications and contraindications

The main indications for the use of ointment are the following pathological conditions:

• infections of the anterior part of the eye, caused by microflora, sensitive to gentamicin (conjunctivitis, keratitis, blepharitis, barley);
• allergic processes in the anterior part of the eye, which are accompanied by bacterial infection;
• treatment, prevention of inflammation in the postoperative period.

  Types of conjunctivitis

Data of clinical trials regarding the use of Dex-Gentamycin during pregnancy, lactation, in childhood are absent.

Contraindications:

• treelike keratitis, chicken pox, other viral lesions of the conjunctiva and cornea;
• mycobacterial infections;
• fungal diseases of the eyes;
• purulent diseases in an acute form, accompanied by defeat of the corneal epithelium;
• increased intraocular pressure;
• corneal epitheliopathy;
• hypersensitivity to drug components.

During treatment with Dexa-Gentamicin ointment, contact lenses are not recommended.

Possible complications

In rare cases, there are allergic reactions, a burning sensation.Long-term treatment with the drug may cause the development of steroid cataracts, secondary glaucoma, so strictly follow the doctor's prescriptions.

Use Dexa-Gentamicin ointment for more than 2-3 weeks can not be to avoid the development of secondary glaucoma or steroid cataract.

If undesirable side effects occur, the use of the ointment should be discontinued.Immediately after its application, a short-term disturbance of visual acuity may occur, therefore immediately before work with the traumatic mechanisms, the driving of motor vehicles is not recommended.

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conclusions

Eye ointment Dexa-Gentamycin is actively used in ophthalmology for the treatment of infectious and allergic diseases eye, as well as as a preventive measure, preventing secondary infection in the postoperative period. The duration of therapy should not exceed 2-3 weeks. The drug has a wide range of contraindications, data on its use during pregnancy, breast-feeding and in childhood there (that is, therapy is possible, but strictly according to the doctor's prescription).