Fezam

At the heart of the preparation Fezam are substances such as pyracetam and cinnarizine. These components have an antihypoxic effect that dilates the blood vessels.

In this case, the effect of these substances increases the effectiveness of visual, auditory functions of the body, improve the quality of blood flow through the vessels. This medication stimulates brain cell metabolism, intensively removes excess glucose, increases the protective function of brain tissue.

Fezam is recommended for use in Meniere's disease, various migraines, complex measures of visual impairment, and hearing.

Clinical and pharmacological group

A drug that improves blood circulation and brain metabolism.

Terms of sale from pharmacies

Can buyby prescription.

Price

How much does Fezam cost in pharmacies? The average price is at the level of320 rubles.

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Composition and form of release

Fezam is available in the form of capsules. The manufacturer presents two packages - 20 and 60 pieces, which do not differ in dosage. Inside the capsules is a white powder, and the gelatinous shell itself is also white.

The capsules contain 2 main active ingredients, the content of which in one capsule is:

• Cinnarizine - 25 mg.
• Piracetam - 400 mg.

It also contains auxiliary components, which include colloidal silicon dioxide, titanium dioxide, lactose monohydrate, gelatin, magnesium stearate. Fesam capsules are packaged in a blister for 10 pieces.

Pharmacological effect

Fezam has a pronounced vasodilator, nootropic and antihypoxic effects. Included in its composition components cause a decrease in the resistance of blood vessels in the brain and increase the blood flow in them.

The cinnarizine, which is part of Fezam, is a selective blocker of slow calcium channels, which inhibits the entry of calcium ions into cells and reduces their content in the depot of the plasmolemma. It reduces the tone of the smooth muscles of the arterioles and their reaction to such vasoconstrictors as dopamine, epinephrine, vasopressin, norepinephrine, angiotensin. Cinnarizine dilates the vessels of the brain, enhancing the effect of pyracetam, but without affecting blood pressure. At the same time it has moderate antihistaminic activity, reduces the tone of the sympathetic nervous system and the excitability of the vestibular apparatus. Increases the elasticity of erythrocyte membranes, reduces the viscosity of the blood.

Pyracetam improves metabolism in the brain by activating protein and energy metabolism, increasing cell resistance to hypoxia, accelerate the utilization of glucose; improves regional blood flow in the ischemic zone and interneuronal transmission in the central nervous system.

Indications for use

It is shown to Fezam for use in the following diseases and disorders of brain function:

• Meniere's disease;
• arterial hypertension;
• atherosclerosis of cerebral vessels;
• stroke;
• circulatory disorders;
• migraine of different etiology;
• encephalopathy of various types;
• visual impairment;
• asthenia.

Indications Fesam to use are violations of brain activity, memory and mental ability in children.

Contraindications

A number of pathological and physiological conditions of the patient's body are distinguished, in which the reception of Fezam capsules is contraindicated:

• Pregnancy at any time of the course and lactation period (the period of breastfeeding).
• The patient's age is up to 5 years.
• Severe impairment of the functional activity of the liver and kidneys.
• Parkinsonism - a violation of the functional activity of the pyramidal system.
• Individual intolerance to any of the components of the drug.

With caution, the drug is used for Parkinson's disease. Before the appointment of capsules Fezam it is important to exclude the presence of contraindications.

Intended use for pregnancy and lactation

In the course of animal experiments, the absence of any negative effect of Fezam on the growth and development of the fetus was found. However, despite this drug is contraindicated for use in pregnancy. This is due to possible negative changes in the woman's mental state, increased anxiety, lability of the emotional sphere and mood, which theoretically can be bad for the current pregnancy.

Since Fezam penetrates into milk, it is also contraindicated in the period of breastfeeding. If a woman breastfeeding for any reason should take Fezam, then the baby should be transferred to artificial mixtures.

Dosage and route of administration

As indicated in the instructions for use, Fezam is recommended to take 1-2 capsules three times a day for one to three months. The duration of treatment depends on the severity of the disease. The drug, as a rule, take courses - 2-3 courses per year.

Children after 5 years are shown taking 1-2 capsules 1-2 times a day. Capsules are applied for from one and a half to three months. Take capsules need to swallow them whole, without violating the integrity of the capsule. Take the tablet with half a glass of water, and it should not be hot.

Many users ask about capsules how to take - before or after a meal. In the instruction it is a question of that the special difference in that, before meal or after meal to accept means, is not present. But it is optimal to drink capsules 20-30 minutes after eating. It is advisable to drink the medicine every day at the same time.

Doctors warn that it is impossible to take medicine for longer than 3 months - there is a break between the courses.

Adverse Reactions

Fezam can cause side effects. There were recorded cases when patients complained of changes on the part of such systems of organs:

1. Cutaneous - dermatitis, hyperhidrosis, rash, itching.
2. Immune - allergic reactions, hypersensitivity.
3. Musculoskeletal is rigidity.
4. Nervous - headache, vestibular disorders, insomnia, tremor, fatigue, imbalance, worsening of epilepsy.
5. Digestive - indigestion, abdominal pain, nausea, cholestatic jaundice, dry mouth.

There are also mental disorders: depression, increased excitability, anxiety, hallucinations. In some patients, in response to taking the drug, there was increased sweating, weight gain, hemorrhagic disorders, sexual arousal.

Overdose

Overdose of Fezam during the entire period of drug use was recorded very limited number of times.

The drug is safe, and even exceeding the therapeutic dosage several times did not cause significant side effects, which would force a person to stop taking Fezam. The only symptom of an overdose of Fezam in adults may be abdominal pain, which, as a rule, is normally tolerated and does not require withdrawal of the drug. Overdose of Fezam in children is manifested by insomnia, irritation, irritability, tremor, nightmares, hallucinations or convulsions.

If any symptoms of an overdose appear in adults and children, symptomatic treatment should be performed, aimed at arresting unpleasant sensations. In addition, it is recommended to wash the stomach. Overdose of Fezam can also be removed by hemodialysis.

special instructions

Before you start using the drug, read the special instructions:

1. With caution appoint patients with liver and / or kidney disease.
2. In patients with impaired liver function, it is necessary to monitor the content of liver enzymes.
3. Patients should avoid drinking alcohol while taking Fezam.
4. The drug strengthens the activity of thyroid hormones and can cause tremors and anxiety.
5. For renal insufficiency of mild and moderate severity (CC less than 60 ml / min), the therapeutic dose should be reduced or the interval between doses should be increased.

When taking Fezam, patients should be careful in managing means and work with machines and equipment, because at the beginning of treatment, cinnarizine can cause drowsiness.

Compatibility with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Fezam potentiates the action of nootropic and antihypertensive agents.
2. With the simultaneous use of vasodilators enhance the effect of the drug.
3. Fezam improves the tolerability of antipsychotic drugs and tricyclic antidepressants.
4. With simultaneous application with the preparation of Fezam, it is possible to increase the sedative effect of drugs that depress the activity of the central nervous system, tricyclic antidepressants, and also ethanol.

Reviews

We offer you to read reviews of people who used Fezam:

1. Galina. The drug is good, the first day or two in sleep tends, for then later - as a battery energizer "you work while eating Fezam. Weight is typed a little. But to choose you, which is more important. And yet, after cancellations, it only affects me, depressuha and decline of strength. But knowing the reason, you can survive it. You have to pay for everything. I usually start taking Fezam before and during any long-distance tour. Travel, flights, heat, etc., because. me under 60.. Excellent helps!
2. Oleg. After the spasms of the brain began, the neuropathologist prescribed to drink a monthly course of pills "Fezam". But after taking the medicine one week, pains started in the right side, most likely the liver, there is such a fad in the instructions, and the brain is better or not, I can not say anything specific. After that several times I tried to drink tablets, but more than a week could not stand it, apparently, this medicine is not for me.
3. Sofia. My grandmother was prescribed the Fezam, since in her old age she often forgot all sorts of things, confused things in places, and when you start talking to her, she might just not listen. She became very diffused. Fezam helped her a little, a small result was evident. She began to listen to us and even understand what we are saying to her.

Analogues

Structural analogs for the active substance:

• Combbitropyl;
• NooCam;
• Omaron;
• Piracazine.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Store in a dry place, protected from light and out of reach of children, at a temperature not exceeding + 25 ° С.

Shelf life - 3 years.

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