Dufalac is a laxative drug that has been widely spread due to mild effects combined with efficacy.
This remedy is made in the Netherlands. The active substance affects the condition of the intestinal wall, helps to cope with constipation.
On this page you will find all information about Dufalac: the full instructions for use for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Dufalac. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
Laxative.
Conditions of leave from pharmacies
Available without a prescription.
Price list
How much does Dufalac syrup cost? The average price in pharmacies is at the level of300 rubles.
.Form of issue and composition
"Dufalac" is available in the form of a viscous syrup, colorless or light yellow.
- The main active substance is lactulose, its content in 100 ml of syrup is 6, g. The auxiliary component of the preparation is purified water.
Syrup acts in vials of 200, 500 ml, there are even liter. In addition, for convenience, the container is provided with a measuring cup. Another possible form of release is disposable sachets of 15 grams, ten pieces per pack.
Pharmacological effect
Dufalac exerts a hyperosmotic laxative effect, enhances intestinal peristalsis, improves the absorption of calcium and phosphate salts, and also helps to remove ammonium ions from the body.
Colon's intestinal flora splits lactulose into organic acids that reduce pH, and increases osmotic pressure. As a consequence, the volume of intestinal contents increases, which stimulates peristalsis and affects the consistency of the stool. According to reviews, Dufalac effectively helps to get rid of constipation and restore the physiological rhythm of emptying the intestine.
As a prebiotic agent, lactulose stimulates the growth of beneficial bacteria, in particular lactobacilli and bifidobacteria, whereas the growth of potentially dangerous bacteria such as Escherichia coli and Clostridium spp., on the contrary, is suppressed. As a result, it provides a more favorable balance of intestinal microflora.
Indications for use
The main on the list is pronounced chronic constipation. Also, the drug is used to soften the stool for medical purposes with hemorrhoids or before surgery on the large intestine or anal passage.
In addition to these basic indications, there are several other factors that require the use of Dufalac:
- preventive treatment for hepatic encephalopathy, coma, or precoma;
- Pain syndrome, resulting from the removal of hemorrhoids;
- Dysbacteriosis or enteritis in cases of onset of salmonellosis;
- syndrome of putrefactive dyspepsia in acute food poisoning in a child;
- colitis and polyps of the large intestine.
Contraindications
Do not take Dufalac if:
- galactosemia;
- colostomy and ileostomy;
- intestinal obstruction for various reasons;
- suspicions of acute appendicitis;
- increased individual sensitivity to the components of the drug;
- hereditary or acquired intolerance of active substances;
- rectal hemorrhages not of hemorrhoidal genesis;
- diabetes (this item is not a direct ban on the use of the drug, but before using you need to get a doctor's advice).
Application in pregnancy and lactation
Lactulose is a safe ingredient for women while waiting for the baby and feeding it with breast milk, so Dufalac is indicated if necessary. The use of the mother of the medicinal product does not affect the condition of the fetus or newborn, but the dosage and regularity of the reception should be agreed with the observing physician.
Instructions for use
The instructions for use indicate that the dose of Dufalac in the treatment of constipation and to soften the stool for medical purposes is presented in the table.
Patients | Initial dose | Maintenance dose |
Adults | 15-45 ml | 10-25 ml |
Children 7-14 years old | 15 ml | 10 ml |
Children 3-6 years old | 5-10 ml | 5-10 ml |
Children under 3 years | 5 ml | 5 ml |
Typically, the dose may be reduced after 2 days of admission, depending on the need of the patient.
The drug is recommended to take 1 time / in the morning during a meal. Clinical effect occurs in 1-2 days (this is characteristic of the action of lactulose). The dose or frequency of admission is increased if there is no improvement in the patient's condition within 2 days of taking the drug.
In the treatment of hepatic coma and precoma the initial dose is 30-45 ml of syrup 3 Then they are switched to individually selected maintaining dose, in which a soft stool is observed as much as 2-3 from the calculation, so that the pH value of the stool is in the the limits are 5.0-5.5.
In acute cases, Dufalac can be given in the form of enemas in a ratio of 300 ml of Dufalac syrup and 700 ml of water.
How much does Dufalac work?
The manifestation of the therapeutic effect directly depends on the use of a certain dosage and the disease against which the therapy is performed. In addition, Dufalac is characterized by a mild effect, so it can not be called very fast.
The desired result appears 4-12 hours after administration. When answering the question how quickly Dufalac acts, there are cases when it takes even about a day to wait. The child's metabolic processes are much faster, so the effect of Dufalac in them manifests itself after a couple of hours.
Side effects
The use of Dufalac in the first days of treatment can provoke flatulence (increased gas formation). This symptom disappears in a few days on its own.
Perhaps the emergence of side effects from the nervous system: rarely - cramps, headache, dizziness. In rare cases, allergic reactions are noted; arrhythmia, myalgia, increased fatigue, weakness.
Overdose
When taking high doses of the drug, diarrhea and abdominal pain are possible. Abolition of the drug or a decrease in its dose levels these manifestations. In the case of a violation of the electrolyte balance, correction by the introduction of electrolyte solutions is required.
special instructions
In the absence of the effect of taking the drug for several days should consult with a doctor.
- Do not use for pain in the abdomen, nausea, vomiting without verification of the diagnosis.
- Use with caution in patients with diabetes mellitus, especially with inflammatory bowel disease.
- With prolonged treatment (more than 6 months), the level of potassium, chlorine and carbon dioxide in the blood plasma should be regularly monitored.
- Patients with intolerance to galactose, fructose should not use this drug. Dufalac for newborns can only be used under medical supervision.
- Use with caution in patients with gastro-cardial syndrome. In such cases, treatment should begin with low doses and increase them gradually to avoid the development of flatulence.
If diarrhea occurs, you should stop taking lactulose.
Drug Interactions
At simultaneous application with antibiotics of a wide spectrum of action reduction of therapeutic efficiency of a lactulose is possible.
With the simultaneous use of lactulose, the release of active substances from Enteric-soluble drugs with pH-dependent release, due to the fact that it lowers the pH intestinal contents.
Reviews
We picked up some of the people's comments about Dufalac:
- Victor.Took it half a year. Due to the treatment of gastritis and concomitant constipation. It does not matter the drug works. Its main advantage is that it is safe, but ineffective. The longer it takes the worse it helps. The more it is necessary to increase the dose for the result. Started with a dose of 30-35 mg after 5 months of taking 60 mg already with difficulty helped. Works roughly. Or just pushes hard feces or does not work or when you increase the dose you run several times a day with diarrhea. Obviously outdated drug - not perfect. Rather more for young children. When a large dose starts to irritate the stomach.
- Victoria. She gave dyufak to a daughter at three months on the advice of a pediatrician. There were constipation. The syrup is delicious, the baby was drinking with pleasure, BUT!!! The action of the drug did not suit me at all. The child started the strongest gases, his tummy wandered and was sick. The laxative action itself began at least a day after the reception! As a result, and threw this drug, had to look for other options.
- Ksenia. After birth, there were many stitches and to soften the chair I bought Dufalac on the recommendation of my friend. During pregnancy, I have become unaccustomed to sweets (there was disgust), and I did not like the sugary sweet taste, but about the action of the drug, it helps well, does not make you wait long and does not cause addictive. Also the pediatrician assigned it to my child. We did not fit the milk formula, and the chair was broken, we drank the course for 2 weeks, and the chair was restored, the child goes to the toilet every day or every other day.
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Galina. A wonderful tool! Lifebuoy during pregnancy and after childbirth. It suited me very well. There were stitches and every trip to the toilet, much to the dreams of an enema... I remembered about Dufalac and everything was fine already in a week. And by the very pregnancy in 2 weeks.
My child also helps me go. The only thing can be noted, not everyone is going, my friend hell hell started with flatulence and pain, that's when I learned what pobochka. In most it was not. Very sweet, tolerable aftertaste, but effective.
Analogues
Virtually all agents with laxative effect, which are considered analogues of Dufalac, contain lactulose in their composition. It is this substance that helps soften the stool.
- Norma. A pleasant syrup without color. Produced in a small glass bottle, there is a spoon-dispenser.
- Lactulose. It is possible to say with full certainty that this is the best of the analogs. Produced in the form of a dry substance or syrup. It is forbidden to drink the remedy with a strong intestinal obstruction and suspicion of the presence of appendicitis.
- Good luck. A pleasant syrup with caramel flavor, can be given to newborns as prescribed by the doctor. Beforehand, make sure that the patient is not allergic to the components of the composition of the remedy.
Before using analogues, consult your doctor.
Storage conditions and shelf life
The shelf life of Dufalac syrup is 3 years from the date of its manufacture. The drug should be stored in a dark place inaccessible to children at an air temperature of no more than + 25 ° C.
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