Drops, syrup Sinekod - instructions for use
A brief instruction on the use of Sinecode in droplets and syrup, it is used:
- With a strong dry cough of any etiology
- With pertussis
- Before bronchoscopy and other surgical interventions
- To suppress cough before and after operations
The main active ingredient of the Sinekod preparation is Butamirate, which has an antitussive effect of central action. Has anti-inflammatory, expectorant and bronchodilating properties, has a direct effect on cough center, improves blood oxygenation and spirometry, decreasing the resistance of respiratory ways. It is not an alkaloid of opium, neither pharmacologically nor chemically.
Main advantages
- Allowed for use in infants (from 2 months), in the elderly
- A very effective remedy, cough suppression occurs quickly
- A safe drug
- Normalizes respiratory function without depressing the respiratory center
- There are no narcotic substances in the composition
- Has no effect on the gastrointestinal tract
- Can be used for prolonged therapy
It is important that Sinecode for children can be applied from an early age in drops from 2 months, in syrup from 3 years, the intake is taken before meals 4 r / day.
Sinekod - drops and syrup - the official instruction for use
Product Name: Sinekod
Drug formulation: drops and syrup for oral administration
Dosage: drops of 20 ml, syrup 100 and 200 ml.
International Non-patented Name: Butamirate
Group: Means for the treatment of respiratory diseases, for the elimination of symptoms of cough and colds
Farmgroup: Antitussives
Price: Sinekod drops - on average in pharmacies 320-350 rub., Syrup 100 ml. - 200 rubles, 200 ml. - 330 rubles.
Sinecode analogs: Omnitus (tablets, syrup)
Composition
- Sinekod syrup, the instructions for use indicate that it is a clear, colorless liquid with a vanilla scent.
1 ml. syrup contains 1.5 mg of butamirate citrate
Excipients: sodium hydroxide, sodium saccharinate, sorbitol solution 70%, benzoic acid, glycerol, vanillin, ethanol 96%, water.
- Sinecode drops, the instructions for use indicate that it is a clear, yellowish tinge fluid for oral administration.
1 ml. drops contains 5 mg. butamyrate citrate
Excipients: benzoic acid, sorbitol solution 70%, glycerol, vanillin, sodium saccharinate, ethanol 96%, water, sodium hydroxide.
Pharmacological properties
Sinekod is an effective antitussive drug, affecting the cough center, does not belong to the alkaloids opium, facilitates breathing, has bronchodilator effect, improves blood oxygenation and indices spirometry. When administered, butamirate is absorbed completely and quickly. The maximum concentration after taking 150 mg of the drug is achieved in plasma on average after an hour and a half and is, μg / ml. In the blood, the hydrolysis of butamirate begins initially to diethylaminoethoxy ethanol and 2-phenylbutyric acid, which have antitussive activity. These metabolites almost as much as 95% bind to plasma proteins, this explains the long half-life of plasma, which is 6 hours. Excretion of metabolites occurs mainly with urine.
Indications
Suppression of cough in whooping cough, treatment of dry cough of various origin, symptomatic suppression of coughing before bronchoscopy, before and after surgical interventions.
Contraindications
- Pregnancy, lactation
- For drops - the period of the newborn (up to 2 months)
- For syrup - for children under 3 years
- Hypersensitivity to the components of the drug
Action category on the fetus
Since pregnant women had no controlled clinical trials, the use of Sinecode in the first trimester of pregnancy contraindicated, in the II and III trimesters of pregnancy, its use is possible given the potential risk to the fetus and the benefits to the mother. There is also no data on the isolation of butamirate with breast milk, therefore it is not recommended to administer Sinecoda during lactation. In studies conducted on animals, no adverse effects on the fetus were found.
Method of application and dosing
Both syrup and Sinecoda drops should be taken before meals. Before using drops for children under 2 years old, consult a doctor. The measuring cap, which is attached to the syrup should be used when determining the dose of the drug, it must be washed and dried after each application. Keeping the cough for over a week, requires a doctor's advice. The table shows the dosage of droplets and Sinecoda syrup for children, depending on the age and for adult patients.
| Age of child or adult | Syrup | Drops |
| from 2 months to 1 year | 10 drops 4 r / day | |
| 1-3 years | 15 drops 4 r / day | |
| 3-6 years old | 5 ml. 1 teaspoonful. spoon 3p / day | 25 drops 4 r / day |
| 6-12 years old | 10 ml. 2 teas. spoon 3p / day | |
| from 12 years and adults | 15 ml. 3 teas. spoon 3p / day |
Side effect
Sinecode very rarely causes the following side effects:
- From the digestive tract - diarrhea, nausea
- From the side of the central nervous system - drowsiness, dizziness
- Allergic reactions
- From the skin - exanthema
Overdose
Vomiting, drowsiness, diarrhea, nausea, lowering of blood pressure, dizziness. There is no specific antidote. Treatment for overdose - the reception of activated carbon, gastric lavage, symptomatic therapy, aimed at maintaining and preserving the vital functions of the body.
special instructions
Since butamir suppresses cough, it is impossible to take expectorants simultaneously, it can lead to the accumulation of sputum in the respiratory tract, cause bronchospasm or infection of respiratory ways.
Patients with diabetes can use Sinecod, because as sweeteners it contains saccharin and sorbitol. Care must be taken when working with machinery and driving controls, as the drug causes drowsiness.
Interaction with other medicinal products: Not described.
Shelf life and storage conditions: Shelf life 5 years. The sinecode must be stored at a temperature of less than 30 ° C, out of the reach of children.
Manufacturer: Name - Novartis Consumer Helles SA, Switzerland, address: Re de Letraz PO Box 269.
If you used Sinecode children or adults, feedback about the drug may be of interest to our readers, it can be left in the comments.
zdravotvet.ru
Sinecode for cough: form of release and instructions for use
- Application
- Analogues
Sinekod - an anti-inflammatory drug from dry cough, containing butamir, which in turn reduces the excitability of the cough center.
Judging by sociological surveys, Sinecode from cough is considered a very effective drug, which accelerates the course of treatment of patients.
Often, a dry cough is very difficult to prevent, for similar cases previously affected some brain centers to stop the receipt of a signal about the reduction of bronchi with the help of various narcotic drugs, but now the twenty-first century and mankind made a big step in treatment of cough.
The medicine does not fight a cold, but is only intended to eliminate the symptoms of cough, and for greater effect it is recommended to use it together with vitamin complexes. Remember, do not self-medicate, it can lead to negative consequences, so before using, consult with your doctor.
note
Sinecode does not contain narcotic substances, thus it is considered safer.
Strictly observe the dose, as an overdose can lead to dizziness, increased blood pressure, vomiting, general malaise, nausea. In case of such consequences it is necessary to cancel the taking of tablets and start using activated charcoal. Sinekod - a preparation against cough that acts directly, blocking the focus of cough, while not touching the respiratory center.
It acts as a relaxing musculature of the bronchi and improves the patency of the respiratory tract.It is worth noting that the drug works and as anti-inflammatory, improving the performance of external respiration functions, and is also an expectorant. After ingestion, the medicine is immediately absorbed by the gastrointestinal tract.
The substance in the composition has a great connection with the plasma protein, so reaching the highest concentration of the drug in the blood comes after one and a half (,) hours.
A sinecode from a cough is metabolized in the body, it forms pharmacologically active metabolites, and the repeated use of Sinecode does not change the pharmacokinetics.Practically complete elimination of the drug occurs in six hours and is excreted mostly by the kidneys.
Indication for use is cough, and almost any origin. The medicine can be used in the postoperative period, after or before bronchoscopy, and before surgery it is recommended to take inside in the amount of twenty milligrams. The drug is available in the form of tablets, covered with a dense shell (20 milligrams) of syrup and drops for children 5 milligrams / milliliter.
A sinecode from a cough does not have pretty bright contraindications, so it can be eaten even by children.However, the drug should not be used in case of intolerance to any substances that make up its composition. Particular attention should be paid to people suffering from allergic reactions, since the drug can cause itching, redness of skin areas, rash and other side effects.
In order to find out if you are allergic, just hold a small easy test: apply a few drops on the a small patch of skin and observe the reaction if there are no prerequisites for redness or rash - the drug can be used inside.
Important
Do not use for children up to two months (drops), up to three years (syrup), during pregnancy and lactation.
The prices for the medicine are quite budgetary, the cost for syrup ranges from one hundred and fifty (150) to three hundred (300) rubles. Acquire the drug in drops perhaps for one hundred and fifty (150) - two hundred (200) rubles, and you can buy in tablets for two hundred (200) rubles.
Sinecode cough syrup and ways of using it
Coughing in children is much more difficult to treat than for adults, it is for this purpose that a special syrup for Cynecoda cough is developed, which can be given to nursing infants. He is often advised by leading pediatricians, since he is one of the effective drugs.It, as well as dragees, acts directly, acting on the cough center, has an anti-inflammatory effect, removes swelling of the mucous membrane. The positive thing is that the syrup can be taken along with other medicines.
The syrup from the cough sinekod is given to children from the age of three, for babies there are specially drops, in which a sweetening agent is added. The bottle has a dispenser, which makes it easier for parents to give the baby a medicine in the right proportions.
Cough preparation Sinecond in the form of a syrup is released in a darkened glass bottle of 100 and 200 milliliters, has a measuring cap and is protected from unwanted opening by children with a special system.
note
Drops are produced in a darkened glass bottle of 20 milliliters, equipped with a drip dispenser.
Drops for oral administration are prescribed for children from 2 months to a year, 10 drops 4 times a day, from a year up to 3 years for 15 drops 4 times a day, older children should take 25 drops 4 times a day.
Syrup is prescribed for children 3-6 years for 5 ml 3 times a day, children 6-12 years for 10 ml 3 times a day, the elder recommended to take 15 ml 3 times a day. Also, the syrup is prescribed to adults 15 ml 4 times a day. In the form of pills for children 6-12 years old, 1 dragee is prescribed 2 times a day, the older children are prescribed 1 dragee 3 times a day. Adults take 2 pills 2-3 times a day.
What is better Sinecode or Stoptussin, as well as other analogues of the drug
Virtually all drugs have analogs. The closest analogue of the Sinecode is Stoppussin, which is considered to be an excellent cough suppressant, so it's better Sinecode or Stoptussin?
Stopoutsin, like Sinecodus, copes well with children's cough, but it's worth remembering that it is possible to give the Sinecode to babies from two months old, and Stoptussin to children who already have a year.
note
These two medicines are safe and almost no different, but Stopoutsin is cheaper and costs about 85-220 rubles.
There are other analogues of the drug. A good analogue of Sinekod is Broncholitin syrup, it can be given to children from the age of three. The composition of this product includes basil oil, glacine alkaloid and ephedrine. He coughs, but do not recommend using the drug yourself.By the speed of action is considered one of the best, the main thing to observe the dosage, since Broncholitin is toxic. The price of the medicine varies from 80 to 110 rubles.Libexin - is a bronchodilator, slightly reduces the activity of the center of respiration. For children it is specially issued in the form of a syrup, it is applied from two years. There are contraindications: cystitis, pathology, pregnancy, ulcers and others. The price is about 350 rubles.
Erespal - is considered the most effective, has anti-inflammatory properties, cleanses the bronchi and eliminates any cough. It can be prescribed for coughing, expressed by allergy, bronchitis, laryngitis and so on. Price: up to 450 rubles.
Important
The drug has a huge number of contraindications, in addition, it causes side effects. With the greatest caution should be taken people suffering from spasms of bronchi, as this can be very dangerous.
Ascoril - the composition of the drug includes three active ingredients: bromhexine, salbutamol, guaifenesin. The components have expectorant and bronchodilator properties, it is recommended to take with the cough and acute chronic ailments of the respiratory system. The cost of the medicine depends on the dosage and form of release, and the price ranges from 150 to 610 rubles. Russian and, perhaps, the cheapest analogue is the syrup "Licorice root".
The natural remedy for cough that passed the test of time, but it refers to ineffective drugs, so the drug is recommended to be taken together with other medicines. It is positive that the licorice root has a low toxicity. The price is from 17 to 35 rubles. Remember, always consult a doctor before use! Health to you and your loved ones.
.gajmorit.com
Sinekod
Sinekod - a drug with antitussive effect. The active substance in its composition is butamyrate. This substance is not related to opium derivatives (such as codeine), which are also widely represented in the antitussive group, but are only released on prescription. Therefore sinecode is successfully used in children and is sold in pharmacies without a prescription.
Mechanism of action (pharmacodynamics)
With inflammation in the trachea and bronchi, irritation of sensitive nerve endings (receptors) occurs in their walls. On sensitive nerves, the signal from the receptors enters the cough center in the brain. This center generates impulses and sends them along the motor nerves to the muscles of the chest wall. There is a cough, aimed at clearing the bronchi and trachea from sputum and other harmful substances.
Sinekod - antitussive drug of central action.This means that its action is associated with the depression of the cough center in the brain.The sensitivity of this center decreases, and the number of pulses it generates decreases. The cough stops.
It becomes clear why the sinecode can not be taken to relieve coughing with phlegm.With a damp cough, cleansing of the respiratory tract is necessary. When suppressing cough, sputum accumulation in the bronchi will occur, which will lead to the spread of infection and the development of pneumonia. The sinecode should be taken only to facilitate a dry "scratching" cough.
Sinecod has a bronchodilator effect, it promotes the expansion of the bronchi and the reduction of resistance to their air flow. At its application improvement of instrumental indices of airway patency (spirometry) was noted. Its effect is also manifested in an increase in the oxygen content in the blood (oxygenation of the blood).
Distribution in the body (pharmacodynamics)
The sinecode is rapidly absorbed in the gastrointestinal tract. Even in the blood begins its disintegration to metabolites, which also have antitussive efficacy. The maximum concentration of the drug in the blood is noted after, hours after ingestion. Metabolites of butamirate bind well to blood plasma proteins and circulate in it for a long time. Therefore, the sinecode has a fairly long effect. The medicine is excreted in the urine.
Indications for use
Sinekod instructions for use recommend the appointment of a drug for suppressing dry cough with the following diseases and conditions:
- Laryngitis, laryngotracheitis.
- Whooping cough.
- Before bronchoscopy (endoscopic examination of the bronchi).
- Cough before and after the surgery.
If the patient is worried about a severe debilitating cough without sputum, accompanied by sore throat, behind the sternum, a feeling of "scratching "rending" in the throat, his condition will help ease the sinecode. Do not forget that this medicine is predominantly symptomatic. It does not affect the very cause of the disease. Therefore, the sinecode should only be used to temporarily relieve the symptoms. Simultaneously, you need to see a doctor, find out the cause of the cough and start the correct etiotropic (directed to the cause) and pathogenetic (affecting the mechanisms of the development of the disease) treatment. The use of only this drug with a cough will lead to a prolonged course of the disease, increase the risk of complications and most often will be ineffective.
Contraindications
Sinecod is not prescribed for allergic reactions to butamate or other components of the drug (ethyl alcohol, vanillin, benzoic acid, sodium hydroxide, sodium saccharinate, sorbitol, glycerol).
Drops of the synecone are prescribed for children up to 2 months, syrup for children under 3 years. Dragee can be taken from 6 years.
The effect of the drug on the fetus during pregnancy has not been studied, so it is not recommended to take it in the I trimester, and in II and III - with caution, only on strict indications.
It is not recommended to use the medication during breastfeeding.
You can not simultaneously (in one day) take a sinecode and any means with an expectorant action in order to avoid stagnation of sputum in the airways.
Side effects
The sinecode is usually well tolerated. Instructions for use indicate the possibility of developing an allergic reaction.
After taking the sinecode drug sometimes there is nausea, there may be a loose stool.
The drug can cause dizziness and drowsiness, so during its use, you need to be careful when driving vehicles and when working with moving mechanisms.
Syrup and sinekod drops have a pleasant vanilla flavor and sweet taste. Therefore, care should be taken to ensure that children do not have access to this medication. When an overdose of the drug may appear nausea, vomiting, diarrhea, as well as drowsiness, lower blood pressure and dizziness. If such signs appear, the affected person should be given activated carbon and call an ambulance. An overdosage with gastric lavage is treated, with severe poisoning, appropriate therapy is performed. The antidote for sinecode poisoning is unknown.
Form of issue
Drops of sinecodes for oral administration for children are released at a dosage of 5 mg / ml. It is a transparent, almost colorless liquid with a vanilla flavor.
Syrup sinekod has a dosage of 1.5 mg / ml. The volume of the bottle can be 100 or 200 ml. For the convenience of dosage in the package there is a measuring cup. The syrup has a vanilla flavor.
Dragee blueberries are dosed with a dosage of 20 mg of active ingredient in 1 piece.
Tablets sinekod with a dosage of 50 mg of butamirate in 1 piece.
Solution for injection 10 mg in 1 ml.
Dosing and Administration
Drops are taken orally, preferably before meals.
Children up to a year give 10 drops 4 times a day, from year to 3 years - 15 drops 4 times a day, from 3 to 6 years - 25 drops 4 times a day. For older children, it is more convenient to use syrup.
The syrup is taken orally, preferably before meals.
Children 3-6 years are prescribed 5 ml 3 times a day, from 6 to 12 years - 10 ml 3 times a day, from 12 to 18 years - 15 ml of syrup 3 times a day. Adults can take 15 ml of medication 4 times a day.
Dragee is taken orally, washed down with water, without cracking. Children under 6 to 12 years are prescribed 1 tablet twice a day, 12 to 18 years - 1 tablet 3 times a day, adults - 2 tablets 2-3 times a day.
Sinekod tablets can be taken to children over 12 years old for 1 piece 1-2 times a day, adults - 1 piece 2-3 times a day before meals, without chewing.
The solution for injections is administered intravenously 1-2 ml or intramuscularly 1 ml up to 5 times a day at need (mainly in the pre- and postoperative period, as well as during the operational interventions).
ingalin.ru
Cyanosis syrup: how to treat?
Children have catarrhal diseases that are much heavier than adults, especially when they are troubled by a severe cough. Before you start treating the symptom, you need to determine the type of cough - dry or wet. Cough syrup Sinekod is a popular remedy for the treatment of dry cough, it is he who prefers many pediatricians and parents.Effect of the drug
Sinekod - a powerful drug, which has bronchodilator, antitussive, anti-inflammatory properties. The manufacturer of the drug is the Swiss pharmacological company Novaris Consiemer Health SA. The preparation is represented by such pharmacological forms:- children's drops;
- syrup for children and adults;
- tablets covered with a special coating.
Experts note that the use of Sinecode accelerates the elimination of the inflammatory process, As a result, the frequency of coughing attacks is reduced, sputum discharge improves, and recovery.
The main active substance Sinekoda is Butamirate, which has a direct effect on the brain, blocking the cough center. Butamir is cured by a painful paroxysmal cough that occurs with inflammatory-infectious diseases of the respiratory system.Due to the broncholytic properties of the drug, there is a reduction of spasm of the lungs and bronchi, an increase in their lumen. As a result of this action on the bronchi improves the process of sputum discharge, which contains viruses, bacteria, particles of blood. In addition, in the treatment of dry cough Sinekodom reduces the swelling of the bronchi, which is due to the action of the active substance on nonspecific factors of inflammation.
Half an hour after taking the drug, the intensity of coughing attacks decreases and the patient feels better by moistening the bronchial surface. Thus, the drug removes from this organ of the respiratory system inflammation and irritation caused by the penetration of the infection.
Butamirate after ingestion is absorbed in the small intestine, half-elimination of the drug occurs through the kidneys approximately after the expiration of 6 hours after its application.
When is Sinecode appointed?
Sinecod is prescribed for inflammatory processes in the respiratory system, accompanied by a dry cough. Specialists prescribe the drug in such pathological processes:
- acute and chronic bronchitis;
- whooping cough;
- cough from smokers;
- for cough relief during the examination of the respiratory system.
With a damp cough, the drug is not prescribed, it can only be taken at night to relieve the patient of debilitating coughing attacks.
Treatment of cough in children
For the purpose of eliminating cough, Sinekod drops are mostly prescribed in children. If the child is between the ages of 2 months and 1 year, he is prescribed 10 drops 4 times a day. The medicine is taken orally on an empty stomach. You can dilute the drops in a small amount of boiled warm water. Children from one year to three give 15 drops, the rest - 25. Usually, after 3 years, syrup is used to treat cough, and after 12 years - tablets.Contraindications and side effects
Sinecod, like any other medicine, has its contraindications. First of all, therapy with hypersensitivity of the patient's body to the components of the drug becomes impossible. Often, with improper application or overdose, these side effects can occur:- headache;
- dizziness;
- increased fatigue;
- nausea;
- vomiting;
- diarrhea;
- itching;
- hives.
It is strictly prohibited to use expectorants at the same time as Sinecod, as this combination can cause mucus congestion in the airways. It is dangerous in that it increases the risk of developing bronchospasm and possible infection of the respiratory tract.
Analogues Sinekoda are antitussives of bronchodilator and anti-inflammatory action. Among them are Erespal, Ascoril, Fljuditek, Stoptussin.
NasmorkuNet.ru
Sinecode - instructions for use
pharmachologic effect
Sinecode, the instruction on which application is presented below, is an antitussive non-narcotic pharmaceutical agent of direct action. As part of the sinecode, the substance butamate is contained. This drug has a blocking effect on the cough center located in the medulla oblongata. Moreover, as the abstract emphasizes, the sinecode does not act depressingly on respiratory functions.
In addition to antitussive action, the sinecode also has a bronchodilator and some anti-inflammatory action. The drug significantly improves the indices of blood oxygenation and spirometry. When taken orally, the drug is quickly absorbed by the intestinal mucosa. Butamate is characterized by a high degree of connection with the protein substances of the plasma. The highest concentration of sinecode in the blood plasma is observed within one and a half hours after administration. In the body, the metabolism of the drug leads to the formation of metabolites active in pharmacological action. Hydrolysis of the sinecode is carried out in the blood. The metabolites obtained are similar to butamirate in pharmacological activity.
The drug does not accumulate in the body, repeated use of the drug does not change the pharmacokinetics. The half-life of the sinecode is 6 hours. It is excreted from the body mainly by the kidneys in the form of metabolites or in an unchanged form.
Indications for use
Sinecode is used for the manifestation of debilitating non-productive cough of various origin, including with dry debilitating cough during pertussis, coughing of smokers, dry cough with respiratory ways. It is also used to suppress the cough reflex during diagnostic studies (bronchoscopy) and surgical intervention.
Mode of application
The sinecode is recommended to be taken before eating, the drops can be dissolved in a small volume of water. The course of treatment and dose of the drug is prescribed by the attending physician individually.
Sinekod-syrup, instructions for use
Patients aged 3-6 years receive, as a rule, 5 ml of sinecode three times during the day. Patients aged 6-12 years - 10 ml three times a day. 12 years and more - 15 ml three times a day. Adults - 15 ml each, three to four doses per day. When dosing the syrup, it is recommended to use a measuring cap.
Sinecode - instruction for oral administration
The drug is prescribed for children starting from the age of two months. 2 months - 1 year: 10 drops - four times a day.
After one-year age the dose increases. From one to three: 13-15 drops - four times a day.
After the age of three, the maximum dose of "Sinekod" is allowed. Instruction for patients older than 3 years, adolescents and adults: 25 drops four times throughout the day.
Side effects
Treatment with this drug can cause the following side effects in patients: dizziness, headache, fatigue, nausea, stools, itching on the skin, rash, hives.
Contraindications
With individual hypersensitivity to the components of the drug; pulmonary haemorrhage; in the first trimester of pregnancy. Also, syrup is contraindicated in children under the age of three; drops (per os) are contraindicated in children under the age of three months.
Pregnancy
The sinecode is contraindicated in women during the first trimester. In further periods of pregnancy the drug is used solely for the doctor's prescription. At present, there is no information on the allocation of a sinecode with breast milk. When appointing butamirate during lactation, it is recommended to decide on the termination of breastfeeding.
Overdose with the drug "Sinekod"
The instruction warns that overdose can cause the following phenomena: nausea with vomiting, disruption of the intestine, a drop in blood pressure, drowsiness, dizziness and loss consciousness. In cases of overdosage, rinsing of the stomach is done, and enterosorbents are prescribed. Also prescribe osmotic laxatives and drugs to maintain the respiratory system and heart activity.
The preparation is produced in the following forms:
Syrup - bottles made from shaded glass (200 ml), in a set - one bottle with a measuring cap. Drops for oral administration are vials made of shaded glass (20 ml).
Storage conditions
The sinecode is stored in a dry place, the temperature is 15-30 ° C. Shelf life - not more than 5 years. Components of the preparation: 1 cm3 of drops contains: 5 mg of butamirate citrate; auxiliary substances + ethyl alcohol. 10 cm3 of syrup contains: 15 mg of butamirate citrate; Excipients.
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