Ingarone drops in the nose - instructions for use

Ingarone is an antiviral agent whose active ingredient is interferon-gamma.

Gamma interferons are the only way to stimulate cellular immunity, including the most important protective mechanisms of the body. The drug makes the cells of the body immune to the invasion of the virus. It has proved its effectiveness at different stages of the infectious process, providing an early recovery both in the first moments of the disease and at the peak of the disease, even with pneumonia.

On this page you will find all information about Ingaron: the full instruction on the application for this medicine, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ingaron. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Immunomodulating agent with antiviral activity.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Ingaron cost? The average price in pharmacies is at the level of240 rubles.

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Form of issue and composition

Medicinal form - lyophilizate for the preparation of solution for injection (intramuscular and subcutaneous): loose or porous hygroscopic white mass (in vials: 1, 5, 10 or 20 bottles in a cardboard box; 1, 5, 10 or 20 vials in a planar cell package, 1 package in a cardboard bundle; 1, 5, 10 or 20 bottles in the contour cassette, 1 package in a cardboard bundle).

One vial of Ingarone may include 20, 00 IU, 50, 00 IU or 10, 00 IU of interferon-gamma.
The auxiliary component is mannitol.

Pharmacological effect

Recombinant human gamma interferon, consisting of 144 amino acid residues, is deprived of the first three amino acid residues of Cys-Tyr-Cys, replaced by Met. Molecular weight 16.9 kDa. It was obtained by microbiological synthesis in a recombinant strain of Escherichia coli and purified by column chromatography. Specific antiviral activity on cells (human fibroblasts) infected with vesicular stomatitis virus is 2 × 107 U / mg protein.

Activates the production of proteins of the acute phase of inflammation, enhances the expression of the genes C2 and C4 of the components of the complement system. Interferon gamma blocks the synthesis of β-TGF, responsible for the development of pulmonary fibrosis and liver.

Indications for use

Subcutaneous or intramuscular injection of Ingaron is used to treat viral chronic hepatitis B, C, AIDS, HIV, pulmonary tuberculosis, cancer, prostatitis chronic, chlamydiosis of urogenital, genital herpesvirus infection and depriving herpes zoster, treatment of anogenital warts caused by human papillomavirus.

There are reviews about Ingarone, effectively used in the prevention of complications of an infectious nature in patients with chronic granulomatosis.

A solution for the treatment of nasal mucous membranes is used in the treatment, prevention of influenza, ARVI.

Contraindications

Drug therapy Ingarone is contraindicated in patients of the following categories:

With intolerance to the components of the drug;
Children under 7 years;
In pregnancy;
With autoimmune problems (with intramuscular and subcutaneous application);
With diabetes (with intramuscular and subcutaneous application);
With caution in severe allergic reactions.

Application in pregnancy and lactation

Use Ingaron during pregnancy of any period is contraindicated. With lactation, the effect of the drug has not been studied.

Instructions for use

The instructions for use indicate that Ingarone is administered intramuscularly or subcutaneously. Immediately before injection, the contents of the vial are dissolved with 2 ml of injection water.

The dosage regimen is determined individually for each patient. Average applied doses:

In chronic forms of viral hepatitis C and B, as well as immunodeficient conditions, including HIV infection and AIDS, the administration of Ingarone in a daily dose of 50, 00 IU is usually prescribed. The drug should be administered daily or every two days at the specified dose. The average duration of the course is 1-3 months. If there is a need, after 1-2 months, a second course of therapy.
If it is necessary to prevent infection complications in granulomatous disease, the administration of Ingarone in a daily dose of 50, 00 IU is usually prescribed. The dose is administered daily or once every two days. The course dose is 5-15 injections, depending on the degree of risk of complications. If necessary, the course is repeated several weeks later.
In complex treatment regimens for oncological patients, 50, 00 IU of Ingaron per day are prescribed. The dose is given every day or every two days. The duration of therapy is calculated by the attending physician.
In the chronic form of prostatitis, an administration of 10, 00 IU of Ingarone per day (subcutaneously) is usually prescribed. The dose should be administered daily or every other day. Course of treatment (general) - 10 injections.
With urogenital chlamydia, shingles and genital herpes, Ingaron is usually prescribed at a daily dose of 50, 00 IU subcutaneously. The dose should be administered every day or every two days. The course dose is 5 injections.
In anogenital warts associated with HPV, an administration of 100 000 IU Ingarone per day (subcutaneously) is prescribed. The course of treatment is started after cryodestruction, injections are given every day or every two days. Course of treatment (general) - 5 injections.

With weakened immunity, frequent viral infections and against long-term antibiotic treatment, the patient is recommended to use Ingarone in the form of drops in the nose. The contents of the vial are dissolved with 2 ml of physiological sodium chloride solution and instilled in each nasal passage 2 drops 4 times a day. The dose is selected by the doctor, depending on the degree of exhaustion of the body with antibiotics. The duration of the course of therapy is 7-14 days.

Side effects

Correct dosing of the drug does not cause undesirable side effects in patients. Cases of cold symptoms in the form of weakness, fever, head and joint pain may occur with a daily dose of , 0, 00 IU or higher.

At the site of hypodermic injections, there may be a strong redness and soreness.

Overdose

The use of large doses from 1 million. ME at a time accompanied by the appearance of influenza-like syndrome: weakness, headache, fever, arthralgia. It is recommended to stop symptoms with Paracetamol.

special instructions

With pronounced local and general reactions, treatment should be discontinued, in case of severe side effects, corticosteroids should be used to stop them.

Drug Interactions

Ingarone is allowed to combine with any other medications prescribed for ARVI or flu, for example, with antipyretics.

Reviews

We picked up some of the people's reviews about Ingaron:

Larissa. I often get sick, tried many different pills. But more recently the doctor - the immunologist has written out to me Ingaron in the form of drops for a nose. This winter I survived without SARS and flu. So in this review I recommend the drug. Although, it's all purely individual. Before you start taking the drug should consult your doctor in advance.
Peter. Ingaron tried the first time when he contracted the flu. As a doctor and advised, he began digging in as soon as he felt the first signs of the disease. The virus was transferred very easily, there was no heat, weakness and other "classic" influenza symptoms. Now I use it for prophylaxis.

Analogues

Most often for intranasal use the following drugs are used:

Grippferon (Russia) - 10 ml bottle costs 250 rubles;
Interferon human leukocyte (Russia) - solution for intranasal use and performance of inhalations 1000 IU, price 120 rubles per bottle;
Alfarona (Russia) - powder lf 50000 IU, the price is 1100 rubles.

Before using analogues, consult your doctor.

Storage conditions and shelf life

It is stored in a dry place, away from sunlight, and at a temperature of no higher than 25 degrees. The diluted solution is stored for no more than 10 days (only in the refrigerator). Overdue drug will not cause any special harm, but it will not be of any use to him.