Driptan is an M-cholinolytic drug that has an antispasmodic and myotropic drug effect on the smooth muscles of the internal organs.
The greatest tropicity he has in relation to the urinary canals. Relaxing the muscle tissue that forms the walls of the bladder, the drug increases its volume. In addition, the frequency of muscle contractions of this organ decreases, cramps stop, which helps to remove the symptoms of false urge to urinate.
On this page you will find all information about Driptan: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Driptan. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
M-holinoblokator from the group of tertiary amines.
Conditions of leave from pharmacies
It is released on prescription.
Price list
How much does Driptan cost? The average price in pharmacies is at the level of700 rubles.
Form of issue and composition
The drug is offered in the form of white tablets, sometimes yellowish. The package contains 30 pieces. Also in the pharmacies you can buy a package of 60 tablets.
Composition of the product:
- active substance hydroxybutine hydrochloride 0.005 g;
- MCC (excipient);
- lactose (excipient);
- calcium stearate (auxiliary component).
Pharmacological effect
This drug helps reduce the tone of the smooth muscles of the bile ducts, the bladder, the gastrointestinal tract, increases the volume of the urinary tract bladder, helps reduce the number of contractions of the muscles of the bladder, relieves spasms, and also provides a restraining urge to urinate.
Indications for use
Adults are prescribed in such cases:
- Urinary incontinence;
- Instability of detrusor function;
- In order to control the hyperactivity of the bladder, which can occur after surgery on the prostate gland or bladder, as well as with concomitant cystitis;
- Rapid urination or imperative urges for unstable bladder function as a result of its neurogenic dysfunction (hyperreflexia detrusor), which can be observed in diseases such as multiple sclerosis, spina bifida, idiopathic hyperactivity of the bladder.
Children are indicated for use in such situations:
- Night enuresis, which is associated with detrusor hyperactivity.
- Urinary incontinence, frequent urination or imperative urges for unstable bladder function as a result of its neurogenic dysfunction, idiopathic hyperactivity of the bladder.
Contraindications
Driptan is not prescribed for:
- bleeding;
- lactation;
- GI tract obstruction;
- angle-closure glaucoma;
- myasthenia gravis;
- obstructive uropathy;
- atony of the intestine;
- expansion of the colon;
- ulcerative colitis;
- hypersensitivity to the acting, auxiliary components of Driptan tablets;
- indications in children under 5 years.
With extreme caution, Driptan is prescribed for:
- hernia of esophagus;
- hepatic insufficiency;
- arterial hypotension;
- pregnancy;
- renal failure;
- IHD;
- hyperplasia of the prostate of benign nature;
- arrhythmias;
- hyperthyroidism;
- heart failure.
Application in pregnancy and lactation
In pregnancy, oxybutynin is used only on strict indications, when the expected benefit to the mother exceeds the potential risk to the fetus.
Oxibutinin is contraindicated in lactation.
Instructions for use
The instructions for use indicate that Driptan is taken orally.
- Adults - 5 mg 2-3 times / day. At elderly patients at the beginning of treatment apply 2.5-3 mg 2 times / day, then if necessary, gradually increase the dose to 5 mg 2 times / day.
- Children older than 5 years - the initial dose of 2.5-3 mg 2 times / day, if necessary gradually increase the dose to 5 mg 2-3 times / day. At night enuresis, the last dose should be taken immediately before bedtime.
Side effects
The use of Driptan can cause the following side effects on the part of various life systems of the body:
- Central nervous system: general weakness, insomnia or drowsiness, headache, vertigo;
- Digestive system: dry mouth, diarrhea and / or constipation, nausea, discomfort in the abdominal area;
- Organs of vision: dilated pupils, impaired vision, dry conjunctiva, increased intraocular pressure, narrow-angle glaucoma;
- Other: decreased sweating, delayed urination, allergic reactions, arrhythmias, impotence.
Overdose
When ingesting tablets in a high dose or against a background of prolonged uncontrolled use of the drug, the patients develop signs of an overdose that are manifested by the following symptoms:
- Vomiting, nausea;
- Decrease in blood pressure;
- Febrile state;
- Development of insufficiency on the part of the respiratory system;
- Anxiety, irritability, disorientation in space, hallucinations, delirium, sleep disturbances, nightmares.
- In severe cases, in the absence of adequate medical care, the patient may develop coma and paralysis.
Treatment of an overdose: gastric lavage, symptomatic therapy, artificial ventilation, the use of neostigmine, diazepam or propranolol. If urinary retention occurs, the bladder can be catheterized.
special instructions
They are used with caution in elderly patients, with NCD, violations of liver or kidney function, thyrotoxicosis, arrhythmia, IHD, chronic heart failure, arterial hypertension, primary manifestations of benign prostatic hyperplasia, NNC, in patients with ileostomy, colostomy, and hernia of the esophagus of the diaphragm, accompanied by reflux esophagitis.
Drug Interactions
When used simultaneously with drugs that have an anticholinergic effect, it can be amplified.
With simultaneous application of itraconazole increases the concentration of oxybutynin in the blood plasma.
Reviews
We picked up some of the people's opinions about Driptan:
- Lera. The drug was taken last year. The doctor said that it should take no more than 5 days. It seemed to me that I began to run to the toilet less often. Analyzes and ultrasound is normal. And the symptoms are: very strong to unbearable pain, the urge to urinate. Already to trembling and moisturizing the eyes, tk has to very strongly compress the muscles and legs and generally exert a superhuman effort. If there are already forces to restrain, then urine leaves and it can not be stopped. I go wet, the maxi urological pads can not absorb everything. And a constant feeling of fullness of the bladder. Quality of life on ZERO. Today I turned again to Driptan. Maybe something will change.
Reviews about Driptane for children are ambiguous. Doctors often prescribe Driptan for enuresis and bedwetting in children. But due to the fact that side effects in children are more often and more pronounced, parents stop giving the drug to their children. Many believe that the drug is not suitable for children, replace it with analogs.
Analogues
Driptan analogues include Oxybutynin, Sibutin, Vesicar, Dream-Apo, Detrusitol, Spasmox, Urocholum, Zevesin, Urotol.
Before using analogues, consult your doctor.
Storage conditions and shelf life
The drug is stored for three years from the date of manufacture. Pharmacological properties of the drug are preserved when stored in a room with room temperature - not above 25 degrees and not below 10 degrees. If there is a violation of the temperature regime of storage, a more rapid deterioration is possible.
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