Anesthetics for arthritis

Content

  • 1Anesthetics used in arthritis
    • 1.1What anesthetics are used for arthritis
    • 1.2How to choose an anesthetic?
    • 1.3Why diclofenac remains the most sought-after remedy?
    • 1.4Modern preparations for the treatment of arthritis
    • 1.5Antirheumatic drugs
  • 2Anesthetics for arthritis: analgesics and NSAIDs
    • 2.1Arthritis and classification of the disease
    • 2.2Symptoms of arthritis of joints
    • 2.3Pain management and classification of analgesics
    • 2.4Examples of NSAIDs in joint diseases
    • 2.5Instead of concluding
  • 3The best analgesic for rheumatoid arthritis
    • 3.1Nonsteroidal anti-inflammatory drugs (NPS)
    • 3.2Non-selective nps include:
    • 3.3Selective NPS (Celebrex, Arcoxia)
    • 3.4Medications for overcoming pain in rheumatoid arthritis
    • 3.5Methods of treatment for rheumatoid arthritis
  • 4Anesthetics for arthritis: how to relieve pain with drugs
    • 4.1Arthritis of joints and its variants
    • 4.2Characteristic symptoms of arthritis
    • 4.3What drugs will help relieve the pain
    • 4.4Examples of modern NSAIDs
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  • 5Review of modern preparations for arthritis
    • 5.1Analgesics (painkillers)
    • 5.2Principle of operation
    • 5.3Application of analgesics: it is important to know
    • 5.4Principle of operation
    • 5.5NSAID use: it's important to know
    • 5.6Disease-modifying antirheumatic drugs (BMAP)
    • 5.7Application of BMPAR: it is important to know
    • 5.8Preparations-biological agents
    • 5.9Principle of operation
    • 5.10Application of biological agents: it is important to know
    • 5.11Operating principle
    • 5.12Corticosteroids: it's important to know
    • 5.13What is better to treat arthritis?
    • 5.14Conclusion

Anesthetics used in arthritis

As you know, problems with joints are one of the most unpleasant, and often you have to use painkillers for arthritis.

This ailment is most often diagnosed in the elderly. It is impossible to get rid of arthritis completely. However, with the help of special medicines, you can achieve this result in order to live a normal life and not think about your illness.

This disease brings a lot of unpleasant symptoms. One of them is pain.

In order to get rid of the pain and get the opportunity to lead a normal lifestyle, you need to choose the right medicines.

There is a huge selection of drugs that will help eliminate pain in a matter of minutes.

But many drugs of this type have a lot of contraindications and side effects, so for long-term treatment they are not suitable. That's why before choosing a suitable drug for yourself, you should definitely consult with your doctor.

What anesthetics are used for arthritis

Despite the fact that the pharmacological industry produces a huge number of different drugs to eliminate pain, not all of them are suitable for the treatment of arthritis. Moreover, much depends on the type of ailment and the reason why it originated in the human body.

Often, to eliminate severe pain during attacks of arthritis, analgesics are used. These medicines can only stop the symptom, but they do not work to stop the development of the disease.

The constant use of analgesics can lead to the fact that the disease will pass into a chronic form. In this case, the fight with pain will often and throughout life.

If such medications only bring temporary relief, after which their re-use is required, then it is necessary to abandon analgesics and urgently seek medical attention.

To eliminate pain during arthritis, non-steroidal anti-inflammatory drugs, i.e., NSAIDs, can be used. There are a number of drugs that:

  • perfectly relieve the pain in the joints;
  • relieve inflammation;
  • inhibit further development of the disease.

But they must be used as carefully as possible. Such painkillers can cause a lot of side effects if they are not applied correctly.

How to choose an anesthetic?

Drugs from this category can only have a temporary effect, so they are not suitable for treating the disease and for prolonged use. Not all drugs that give an analgesic effect have the same effect on the body.

For example, drugs with paracetamol can further reduce the elevated body temperature. Medications with analgin just relieve the pain and no longer have any effect.

If you use drugs with diclofenac, you can get rid of unpleasant symptoms, inflammation and many other problems. But such tools, as a rule, have many side effects.

Therefore, without the recommendation of a doctor, they can not be used.

The best results in the fight against arthritis are shown by NSAIDs. It is not only anesthetic tablets, but also external tools. Such drugs are very convenient to use for the treatment of arthritis, since it is possible to apply ointments and gels directly to the affected areas.

This ensures that the number of side effects will be minimal. Non-steroidal anti-inflammatory drugs can be purchased in the form of tablets, ointments, gels, injection fluids, as well as powders and patches. Everyone can find the most suitable option for themselves.

It is worth noting that for a long time diclofenac was considered the best analgesic for pain in the joints. It was a classic solution if you need to get rid of pain and inflammation.

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But people who have been treated with this drug, often faced with such side effects as gastric and intestinal pathologies.

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This can happen if you use the medicine inside.

Nowadays, the number of drugs that include diclofenac and ibuprofen is just huge. But they became safer, and most importantly, comfortable.

A huge advantage of modern painkillers is that they not only relieve unpleasant symptoms, but also have a minimum effect on internal organs. For example, if ointments and gels are used to treat arthritis, then the stomach and intestines will not suffer from this.

Why diclofenac remains the most sought-after remedy?

Recently, the number of painkillers that are offered by the pharmaceutical industry has become immense.

If a person turns to a pharmacist with a request to give something from pain in muscles and joints, then he will be offered dozens of different means.

They are very different in price, but sometimes they are absolutely similar in their impact on the problem area. Therefore, always carefully read the composition of the drug.

Very often one of the main components of analgesic ointments and gels is diclofenac. This substance is used to treat arthritis, osteochondrosis and many other ailments that cause inflammation and pain.

Diclofenac can be found in various forms of release. For example, you can buy a gel or ointment with a similar name. As a rule, they differ in the amount of active substance, in the gel it is greater.

In turn, the ointment has a longer lasting effect. But even diclofenac occurs in the form of a liquid (in order to make an injection), in the form of tablets and even rectal suppositories.

This substance is widely used in medicine for the treatment of various diseases.

If used improperly, diclofenac can lead to:

  • disruption of the gastrointestinal tract;
  • the appearance of ulcers;
  • bleeding in the stomach;
  • an allergic reaction, including rashes on the skin.

Under the influence of diclofenac, changes in blood composition may occur. But such a side effect is available only in those medicines that are intended for oral administration.

Some time ago a group of scientists found out that diclofenac has a strong influence on the blood and the work of the heart muscle. When it is used continuously in the form of tablets or injections, there may be a myocardial infarction.

But most often with the correct dosage and use of external means, such problems do not arise.

For the treatment of arthritis, diclofenac is well suited as a gel or ointment. In addition, you can use drugs with this component, for example, "Voltaren".

It acts similarly, however, it costs several times more.

Modern preparations for the treatment of arthritis

Despite the fact that many doctors still appoint their patients to get rid of pain and inflammation of ointments with diclofenac, on sale there is more and more safe and effective means. A lot of modern drugs not only relieve pain more quickly, but they have fewer side effects and contraindications.

For example, if you use the painkiller "Meloksikam then you can not be afraid for your stomach. This means does not affect the operation of the digestive tract in any way.

However, "Meloksikam" can not be called an absolutely ideal tool. Among its side effects include headache and a change in the blood formula.

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However, this analgesic has 1 indisputable plus, namely long-term effects on the body.

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One of the high-quality pain killers with a long-lasting effect is Nimesulide. This drug can often be found in the form of a powder that is diluted in water and taken internally. "Nimesulide" has no side effects, if not to break the dosage.

A good modern drug, which is often prescribed to patients with arthritis, is "Celecoxib." It can be purchased at the pharmacy only by prescription from a doctor. Therefore, in advance, you still need to consult a specialist.

There are no special restrictions when using this tool. Nevertheless, if a person is allergic to one or more of the components of "celecoxib it is necessary to abandon the use of an anesthetic of this type.

At the moment, this drug is considered one of the most effective and safe in rheumatoid arthritis.

Antirheumatic drugs

Such medicines are prescribed for people with rheumatoid arthritis. In general, their use is considered justified with a serious risk of irreversible destruction of the articular tissue.

Properly selected drugs make it possible to stop the disease, which plays an important role for patients with arthritis. Completely cure this ailment will not work, but to slow down its progression is quite real.

This ensures that the pain will return much less often.

Antirheumatic drugs have no analgesic effect. However, they directly affect the problem site and protect the joints from further destruction, while the rheumatic disease stops its development. The category of such medicines includes:

  • "Imuran
  • Arava;
  • "Plakvenil."

Their peculiarity is that even prolonged use does not lead to side effects. But despite the safety of such drugs, it is better to consult a doctor before using them.

A source: https://OrtoCure.ru/kosti-i-sustavy/artrit/obezbolivayushhie.html

Anesthetics for arthritis: analgesics and NSAIDs

In our country, any pensioner will tell about the treatment of arthritis more than all academicians of the Russian Academy of Sciences.

Pensioners will confidently advise you and anesthetic for arthritis.

However, no matter how many times the truth is repeated, that self-medication and word of mouth will not replace a trip to the doctor, it will not become less popular.

Our goal is not to prescribe to you a universal anesthetic.

The main thing for us is to understand the terminology of the disease and describe the existing medicines.

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That you, having this information, could receive a high-quality medical consultation and understand the prescription for treatment.

Arthritis and classification of the disease

Arthritis is not a specific disease. This is a collective designation for a number of joint diseases. It used to be that arthritis is a disease of the elderly, but due to a number of external and internal factors this disease is getting younger.

Distinguish between chronic and acute arthritis.

Arthritis can be:

  • an independent disease,
  • a symptom of another disease (for example, with rheumatism arthritis is called rheumatoid);
  • the manifestation of an adverse reaction of the body (for example, reactive arthritis after intestinal infections).

The cause of arthritis can be:

  • hereditary abnormalities;
  • inflammatory processes (infections);
  • injuries;
  • age disorders (due to the gradual destruction of connective tissue with age or prolonged deposition in the body of products of life).

As you can see, the causes of arthritis and polyarthritis (multiple joints at the same time) are so many that there can not be a single prescription for treatment.

And yet the most frequent option, age-related arthritis, is a disease of the elderly. And they are familiar with the symptoms better than anyone.

Symptoms of arthritis of joints

Naturally, each separate type of disease has its own, special symptoms, which help to diagnose it, but we will describe the general ones.

They include:

  • pain in the joints (the type of pain is absolutely different: stitching, aching, pulling, etc.);
  • swelling;
  • redness of the skin;
  • change in the shape of the joint;
  • the lack of mobility or its limitation;
  • a crunch of bones in the joints.

The very first and most intolerable symptom for any person, of course, is pain. To remove it, people and use various painkillers.

Pain management and classification of analgesics

We hope that after reading it becomes clear that with the help of analgesics arthritis can not be cured. You can only stop the pain symptom.

This means that the fight against the disease as such does not happen. Especially it is important to understand with acute arthritis.

If you do not overcome the disease in time, do not reveal its cause, arthritis will become chronic. Then the war with pain will become permanent.

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Naturally, you yourself can not prescribe a treatment, but it's easy to understand the assortment of painkillers.

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After all, your health is the only thing that will ultimately show the effectiveness of a drug.

And no matter how the doctor, advertising or numerous sympathizers praised the drug, if you do not feel relief, it is useless.

A little pharmacology. The action of analgesics is very diverse and depends on the chemical structure of the substance. Analgesics can be divided into:

  • narcotic;
  • non-narcotic.

Naturally, we will stop at the second. They mostly operate on enzymes, the isolation of which provokes pain and inflammation, the so-called enzymes COX1 and COX2.

Not all analgesics anesthetize and help fight pain with arthritis.

Some drugs have only antipyretic effect (paracetamol), some poorly penetrate into the joint tissues (eg, diclofenac for external use), some do not exhibit anti-inflammatory effects (analgin).

Anesthetic drugs that also suppress inflammatory processes are called non-steroidal anti-inflammatory drugs, or NSAIDs. Here they are most effective for pain in the joints.

Do not forget that pills - this is not the only method to combat pain. There are also anesthetic powders, ointments, gels, patches, injections with severe pain. However, most often the active substances in them are the same.

Examples of NSAIDs in joint diseases

Since the days of Hippocrates, pharmaceuticals do not stand still, but constantly explore the human body, medicinal substances and their interaction.

Modern painkillers for arthritis quickly move forward from the classic and well-known diclofenac and ibuprofen.

The current medicines are deprived of many side effects, because of which whole generations of patients suffered.

The main effect, in addition to anesthesia, of almost all NSAIDs was a negative effect on the mucosa of the gastrointestinal tract.

The ulcer was a constant companion of patients using anti-inflammatory drugs.

Today, thanks to the preparations of the following generations, if not to solve this problem, then in many ways to reduce this action.

Consider a few of the most common NSAIDs (we will not have in mind trademarks of drugs, but only the active substance). Find out which drug is based on this substance, you can by reading the information on the package or by asking the pharmacist at the pharmacy.

Diclofenac sodium is one of the old and proven drugs. He is referred to as "Vital essential and essential medicines" (a list created by the Government of the Russian Federation).

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Produced in the form of tablets, capsules, ointments, gels, patches, suppositories, lipogels, in ampouled form. Has an anti-inflammatory and analgesic effect.

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However, this drug has a wide range of contraindications and side effects.

Among them:

  • disorders of the digestive system;
  • gastric bleeding;
  • skin rashes;
  • violations of the blood formula;
  • can mask infectious diseases at the initial stages;
  • increased risk of heart attack.

Today there are more effective drugs that are used for chronic arthritis.

Preparations meloxicam have a pronounced anti-inflammatory and analgesic effect.

Meloksikam - NSAID of the next generation, it selectively blocks enzymes, which allows to avoid a dramatically negative effect on the stomach.

Of the side effects remains:

  • change in the blood formula;
  • headache;
  • digestive disorders;
  • skin rashes.

Meloksikam is convenient in that it is applied once a day. This is important for the elderly, who forget the complicated schedules of taking medication.

Nimesulide is an effective preparation, which began to be produced in the form of powders. It is easily digested, it is convenient to drink this solution immediately after ingestion. Long and effective. Has a selective effect on the enzymes COX-2.

Side effects almost does not cause, only for patients with exacerbations of diseases of the digestive and excretory systems.

However, do not forget to monitor the function of the kidneys and liver of older people with prolonged use of nimesulide drugs.

Tselecomib is the representative of the new generation of the NSPF. Also selective in action at the OCT-2. It is used, like nimesulide, only after consultation with a doctor, it is released by prescription. One of the fastest analgesics.

Has no significant contraindications, only with the aggravation of any disease, as well as with increased sensitivity to the active substance.

For the elderly, it is very important to adjust the course of treatment taking into account the body weight, since the dose of the drug may be overestimated.

Instead of concluding

As we see, diseases of the joints are very well known to mankind, therefore, they have been studied as much as possible.

For them, treatment protocols have been developed, and medicines are constantly being improved.

Do not just treat yourself or using unskilled help.

Be sure to consult a doctor before treatment of illnesses. This will help to take into account individual tolerance, confirm the diagnosis, make sure the treatment is correct and exclude the negative interactions of the drugs. If you use prescriptions without consulting a doctor, it is entirely at your own risk. All information on the site is provided for informational purposes and is not a medical benefit. All responsibility for the application lies with you.

A source: http://artrozmed.ru/artrit/primenenie-obezbolivayushhix-pri-artrite.html

The best analgesic for rheumatoid arthritis

There is a large spectrumpainkillersfor pain relief withchronic joint diseases- arthritis, arthrosis, with rheumatitis, from which your doctor will choose the drugs that suit you.

Unlike the basic drugs for the treatment of rheumatoid arthritis (DMARD), these drugs do not slow down the destructive process in the joints, which can be triggered by rheumatoid arthritis.

But they make life easier for people with this disease.

Below are the most popular analgesic anti-inflammatory drugs prescribed for rheumatoid arthritis in German clinics.

Nonsteroidal anti-inflammatory drugs (NPS)

Non-steroidal anti-inflammatory drugs- the main drugs that eliminate pain in rheumatoid arthritis. They effectively anesthetize, eliminate puffiness and stiffness in the joint.

Non-steroidal anti-inflammatory drugsblock the production of prostaglandins - substances that cause pain.

NPS (Non-steroidal anti-inflammatory drugs)can be selective and non-selective, depending on the mode of their action.

Non-selective nps include:

  • Diclofenac (diclofenac) (Voltaren, Cataflam)
  • Etodolac (etodolac) (Lodine)
  • Ibuprofen (ibuprofen) (Motrin, Advil)
  • Indomethacin (indomethacin) (Indocin)
  • Meloxicam (meloxicam) (Mobic)
  • Naproxen (naproxen) (Aleve, Naprosyn)

The main drawbackNon-steroidal anti-inflammatory drugs- the possibility of provoking an ulcer or bleeding in the stomach or intestines. Taking an inhibitor of the proton pump, a drug that suppresses the production of hydrochloric acid in the stomach, can reduce this risk.Non-steroidal anti-inflammatory drugsoften cause a general feeling of discomfort in the stomach or upset stomach.

NPS (Non-steroidal anti-inflammatory drugs)can exacerbate manifestations of renal or heart failure. You should be under the close supervision of a doctor if you have such problems and you are taking NPCs.

Selective NPS (Celebrex, Arcoxia)

These drugs are alsoNon-steroidal anti-inflammatory agents. but when they are taken lower risk of ulcers or gastrointestinal bleeding. In doing so, they alleviate the pain as effectively as non-selective NPCs.

SelectiveNon-steroidal anti-inflammatory drugssuitable for people with a high risk of developing gastroenterological bleeding, which requires frequent intake of painkillers.

  • Acetaminophen (acetaminophen) (Tylenol).Acetaminophen- a well-known medicine that is dispensed without a prescription. Its main advantage is security. With compliance with the rules of reception, this drug rarely gives side effects. Exception - people with liver diseases who can take acetaminophen only under the supervision of a doctor.
  • Corticosteroids(Corticosteroids). Corticosteroids are potent drugs that can stop inflammation. They differ from anabolic steroids, such as testosterone, that cause muscle growth. Corticosteroids act on the whole body. with different effects. With rheumatoid arthritis, these drugs suppressexcessive immune activity. which reduces the symptoms and activity of the disease.

Because thecorticosteroidshave a wide range of effects, affecting not only the immune system, they are ideal for the treatment of short flashes of inflammation, thus avoiding side effects.

In acute rheumatoid arthritis, corticosteroids are taken for a long period.

Consult with your doctor regarding possible problems with prolonged use of this drug group, such as an increased predisposition to infections, increased blood sugar (diabetes), thinning bones.

Corticosteroids are sometimes injected directly into the joint, affectedrheumatoid arthritis. This type of use reduces the occurrence of side effects and has a rapid effective therapeutic effect.

Medications for overcoming pain in rheumatoid arthritis

If you have been diagnosed with rheumatoid arthritis, it is important to know about the existing types of painkillers.

One of the fundamental and at the same time, the most obvious principle of treating rheumatoid arthritis is overcoming pain.

There are many effective analgesics that your doctor can recommend.

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In contrast to BPPR (basic anti-inflammatory drugs that modify the course of the disease), these drugs do not slow down the erosion of joints in rheumatoid arthritis. Nevertheless, they help to combat discomfort.

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We offer an overview of the traditional painkillers and anti-inflammatory drugs used in the treatment of rheumatoid arthritis.

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Non-steroidal anti-inflammatory drugs (NSAIDs)

NSAIDs occupy the main place among painkillers used for rheumatoid arthritis. They effectively reduce pain, swelling and stiffness.

The effect of NSAIDs is to suppress the synthesis of specific enzymes (prostaglandins) that cause pain.

They are classified into "selective" and "non-selective" depending on their action.

There are the following non-selective NSAIDs:

Diclofenac (Voltaren, Kataflam)

Ibuprofen (Motrin, Advil)

Naproksen (Aliv, Naprosin)

The main drawbacks of NSAIDs are their ability to cause ulcers and bleeding in the gastrointestinal tract.

To reduce the risk of these complications, you should take a proton pump inhibitor - a drug that suppresses the production of acid in the stomach.

NSAIDs can also cause stomach upsets and general discomfort.

NSAIDs can cause complications if you suffer from kidney failure or heart disease. Before you start taking NSAIDs, you need to notify your doctor about these conditions.

Selective NSAIDs (Celebrex, Arcoxia)

These drugs are included in the category of NSAIDs, but have a lower risk of ulcers and gastrointestinal bleeding. They alleviate pain to the same extent as non-selective NSAIDs.

In 2004 and 2005, two selective NSAIDs, Viks and Bekstra, were withdrawn from the market by producers.

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The results of clinical studies revealed an increased risk of heart attacks and strokes due to the use of these drugs.

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Celebrex, used in certain doses (200 milligrams daily), showed no similar effects, and is still used in RA.

Selective NSAIDs are most suitable for persons highly prone to gastrointestinal bleeding and in need of regular use of painkillers.

Acetaminophen is a common drug that is on sale. Its main advantage is safety of use.

In appropriate doses, it causes a minimum of side effects in most people.

The exception is people with complications of the liver, so they should take acetaminophen under the supervision of a doctor.

Corticosteroids are potent drugs that stop the inflammatory process. They are different from anabolic steroids, such as testosterone, which promotes the growth of muscle mass.

The action of corticosteroids extends to the entire body.

In rheumatoid arthritis, the main advantage of corticosteroids is their ability to suppress the hyperactivity of the immune system, alleviate symptoms and slow the course of the disease.

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Due to the fact that the action of corticosteroids in addition to the immune system extends to other body systems, they are more suitable for the elimination of short-term outbreaks of the disease. This reduces the risk of side effects.

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If you have acute rheumatoid arthritis, you may need a longer course of corticosteroid treatment. During this course, your doctor will monitor the manifestation of side effects.

Among the complications may be increased susceptibility to infections, high blood sugar (diabetes) and thinning of bone tissue (osteoporosis).

Corticosteroids are sometimes injected directly into the joints affected by rheumatoid arthritis. This is the optimal option to achieve a therapeutic effect with a low spectrum of side effects.

Methods of treatment for rheumatoid arthritis

Rheumatoid arthritis is a systemic chronic connective tissue disease. Small peripheral joints are most often affected, where erosive and destructive changes subsequently develop. It belongs to the class of autoimmune diseases.

The disease is more common in women. This is due to the peculiarities of the female body.

The causes of the disease are still unknown. It is assumed that the disease occurs as a result of an infection that leads to disturbances in the immune system in people with a hereditary predisposition. An important factor affecting the onset of the disease is the external environment.

Modern medicine uses a comprehensivetreatment for rheumatoid arthritis. However, the disease is not completely cured. Complex treatment combines: symptomatic therapy, which aims to relieve pain, therapy that affects the development of the disease.

Than to treat rheumatoid arthritis. The first thing the patient wants is to reduce pain. In this case, non-steroidal anti-inflammatory drugs, analgesics are most often used.

But it is worth considering the fact that these drugs can cause side effects from the gastrointestinal tract. As an alternative use another group of drugs - inhibitors.

This group includesrheumatoid arthritis medication. namedArkoxia. Thisrheumatoid arthritis- Selective inhibitor reduces the formation of prostaglandins.

Arkoxiahas anti-inflammatory, antipyretic, analgesic effect. The drug is used asanalgesic for rheumatoid arthritis.

Before using, consult a doctor!

As drugs that affect the development of the disease, use glucocorticoids and injections, Protecting the joint and bone tissue from destruction, immunosuppressors, which reduce the activity immune system.

In the treatment,recipes from rheumatoid arthritis. related to folk medicine.

Medicinal plants are used: elm, gentian yellow, oats, thistle, wheat germ, pine, poplar, beans, mint, primula, walnut, dandelion, sorrel, St. John's wort, cherry, raspberry, celery, tansy, sunflower, horsetail, heather, chestnut, burdock, cabbage.

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In addition, they use: rubbing with salt, paraffin, mud treatment, treatment with honey, bee venom, royal jelly, bile, acupuncture, therapeutic gymnastics.

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Sources: http://clinics-de.org/blog/2013-03-03-104, http://www.eurolab.ua/rheumatoid-arthritis/2195/2197/16637, http://mediki-online.ru/metody-lecheniya-pri-revmatoidnom-artrite.html

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Anesthetics for arthritis: how to relieve pain with drugs

Arthritis is a joint disease that is prevalent among elderly patients.

And if you ask them, they will readily advise a lot of miraculous recipes of folk medicine that help to remove swelling, inflammation, joint stiffness, and most importantly - painful pain.

Traditional medicine does not deny the benefits of these prescriptions, but it recalls that with the help of folk remedies it is impossible to completely remove the inflammation of the joints.

They give good results if they are supplemented by properly selected medications: pills, painkillers, gels and injections, as well as various physiotherapy procedures.

This article will help to understand the abundance of modern medicines used to treat arthritis, and understand what, how and why to take when immunosuppressants are required, and when an anesthetic will help.

Arthritis of joints and its variants

Arthritis is a collective term used to refer to numerous pathologies of joints. Arthritis is primarily classified according to its course: distinguish between acute and chronic forms. Also, arthritis is distinguished by its origin:

  • The independent form;
  • As a symptom of another disease - for example, with rheumatism, a disease affecting numerous internal organs and systems, inflammation of the joints is diagnosed rheumatoid arthritis;
  • As an adverse reaction to an infection - if arthritis has occurred under the influence, for example, of an intestinal infection, it is called reactive.

Causes of development may include factors such as heredity and genetic predisposition, trauma, deterioration of joint tissues due to age-related changes in the body.

Obviously, with so many different forms of the disease, a single medicine, effective for each case, can not be.

But since, despite the rapidly growing age of the disease, the most common inflammation of the joints due to age-related changes, drugs for this form of the disease and will be considered in detail.

Characteristic symptoms of arthritis

Symptomatology of the disease may differ depending on its form, but there are common signs by which it is possible to recognize the inflammation of the joints:

  1. Pain can be periodic, permanent, abrupt, aching, scalding, or pulsating.
  2. Puffiness of the joints.
  3. Limitation of mobility.
  4. Changing the contours of the joint.
  5. Crunch when moving, bending, squatting, walking.

What drugs will help relieve the pain

Analgesics and other pain relievers for pain in the joints can not cure the disease - it only reduces pain. This should be remembered, including such drugs in the treatment program, especially if it is a question of rheumatoid arthritis or of an acute form of the disease.

If the acute form eliminates only the pain, and not the root cause, the disease quickly goes into a chronic form. When choosing a drug that relieves pain and inflammation, of course, first and foremost you need to rely on the recommendations of a doctor.

But if the drugs are ineffective, there is no point in their admission.

It is in order to be able to correctly choose an alternative remedy that really effectively removes pain in arthritis, this section of the article is written. All pain relievers are divided into two groups:

  • Narcotic;
  • Non-narcotic.

In acute, rheumatoid or chronic arthritis used drugs of the second group. They have an overwhelming effect on the enzymes that cause pain - these are the enzymes COX1 and COX2.

Not all analgesics are able to eliminate pain in arthritis. For example, paracetamol removes heat very well, but practically does not affect the abovementioned enzymes, which provoke pain syndrome.

Diclofenac in the form of a gel penetrates into the joint tissues only partially, which means it also removes the pain inefficiently.

Analgin, a universal remedy for any pain, will help to feel comfortable for the patient, but will not eliminate inflammation.

Best in the complex treatment of arthritis have proved to be NSAIDs.

NSAIDs are non-steroidal anti-inflammatory ointments and drugs that quickly relieve even very severe pain in the joints, while at the same time stopping the inflammatory process. Ibuprofen, indomethacin, voltaren - these drugs are really effective in joint arthritis.

Most patients are used to fighting with pain pills. However, the same active substance that is contained in the tablets can also be presented in other pharmacological forms, in the form of an ointment, cream, gel, powder or liquid for injection.

What is the advantage of anesthetics of such forms?

Examples of modern NSAIDs

Classical representatives of the NSAID group are diclofenac and ibuprofen.

These drugs are effective and tested, but have one significant drawback - with prolonged admission arise undesirable side effects from the gastrointestinal tract, hematopoietic system, as well as allergic reaction.

Earlier, patients suffering from arthritis and other articular pathologies had to choose: either an ulcer stomach and digestive problems due to the systematic use of NSAIDs, or persistent pain, swelling and discomfort. Nonsteroid drugs with the anti-inflammatory effect of the new generation solved this problem.

A new active substance, which replaced diclofenac sodium - meloxicam.

This chemical agent also effectively removes the symptoms of inflammation and pain syndrome.

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But at the same time it blocks enzymes selectively, and therefore does not act so aggressively on the mucosa of the esophagus, stomach and intestines.

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Some side effects have remained, but they are less frequent and less intense. These include:

  1. Skin rash allergic type;
  2. Changes in blood composition;
  3. Migraine;
  4. Digestive disorders.

A great advantage is that it is enough to take meloxicam once a day - this is important in the home treatment of elderly patients, who often violate the schedule of taking medicines due to senile forgetfulness. And it can have the most negative consequences, especially with rheumatoid arthritis.

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Nimesulide is another substance that is a major component of many new NSAIDs.

Nimesulide gel selectively affects the enzymes COX2, but it has practically no side effects and contraindications. With it, you can combine immunosuppressants, prescribed for rheumatoid arthritis.

The only caveat for arthritis remedies: should be cautious elderly patients with long course of treatment with nimesulide, since renal or hepatic failure.

Celecocib is similar in its effect to nimesulide, it suppresses selectively only the enzymes of COX2. It is also available in the form of a powder and is taken after a meal. But without a doctor's prescription in a pharmacy you can not buy it.

Tselecikib relieves pain faster than all of the substances listed above. Contraindications, like nimesulide, are almost absent, side effects are insignificant.

Medications containing this substance are not prescribed for exacerbation of any diseases.

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It is important to correctly calculate the dosage based on the patient's body weight, especially for people older than middle age.

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A source: https://joints.propto.ru/article/obezbolivayushchie-sredstva-pri-artrite-kak-snyat-bol-preparatami

Review of modern preparations for arthritis

articles:

There are many ways of treating arthritis.

One of the main methods of traditional medicine is drug therapy, which is aimed at eliminating inflammation, alleviating the symptoms of the disease and restoring the functions of the joints. What medicines are used for this? Let's talk more about the pros, cons and features of each group of medicines.

Analgesics (painkillers)

Analgesics are drugs that relieve pain. There are several types of analgesics: on the basis of acetaminophen (released from pharmacies without a prescription), opioid analgesics (dispensed according to the doctor's prescription) and combined agents, which include acetaminophen, and opioid.

Acetaminophen-based medications (eg, Tylenol) are suitable for alleviating moderate pain and discomfort. Opioid and mixed analgesics - Oxycodone, Methadone, Tramadol, Morphine, Oxicontrin, Vicodin and others. - prescribe for severe pain.

Principle of operation

Opioids (synthetic narcotic drugs) bind to the receptors of the cells of the brain, spinal cord and gastrointestinal tract and thus "cut off" the pain centers and block the transmission of painful impulses.

Opioid analgesics are in many cases more effective than acetaminophen, but their use is often accompanied by side effects.

Such medications are taken either on demand or on schedule at regular intervals.

Previously, opioids were used mainly to relieve acute pain (for example, after surgery or serious trauma), but now they are prescribed to alleviate chronic pain, including arthritis. These drugs are a suitable option for patients suffering primarily from severe pain, and not from inflammation.

Non-narcotic analgesics based on acetaminophen act in a different way: they suppress the synthesis certain enzymes involved in the formation of prostaglandins, which are the cause the occurrence of pain. More about prostaglandins a little further.

Advantages of analgesics over non-steroidal anti-inflammatory drugs (namely, to eliminate pain) are higher efficacy and no side effects from the gastrointestinal tract. A significant disadvantage of painkillers is that they do not relieve inflammation, and with prolonged use it is possible to get addictive.

Application of analgesics: it is important to know

If you are advised to treat arthritis with analgesics, be aware:

  • Do not abruptly stop taking medication - this can trigger the occurrence of serious side effects.
  • After the first use of the opioid analgesic, do not drive and do not take other actions that require concentration.

    The medicine has different effects on the body, in some people the rate of reaction decreases, there is drowsiness and light dizziness.

  • If you experience discomfort when swallowing tablets, discuss with your doctor the possibility of using an analgesic in another form, for example, in the form of a patch. The active substance in this case will get to the focus of pain through the skin.

Click on the image to enlarge

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat arthritis: they reduce inflammation and pain.

Principle of operation

If analgesics fight directly with pain, NSAIDs reduce both of the most unpleasant symptoms of the disease: both pain and inflammation. To this group of drugs are Motrin, Advil, Ecotrin, Celebrex, Klinoril, Voltaren, Naprosin, and others.

Nonsteroidal anti-inflammatory drugs block the work of hormone-like substances - prostaglandins. These substances have an important function - they protect the gastric mucosa from their own digestive fluids.

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At the same time it is prostaglandins that are involved in pain and inflammation. NSAIDs just block the work of prostaglandins.

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Pain and inflammation are weakened, but the gastric mucosa becomes more vulnerable to ulceration and bleeding.

NSAID use: it's important to know

Non-steroidal anti-inflammatory drugs demonstrate excellent results in the therapy of arthritis, but the use of these medicines has its own nuances:

  • These drugs are not recommended for patients with gastric ulcer, the presence of gastric bleeding in the past, liver, kidney, heart, asthma and hypertension.
  • The intake of any NSAID is accompanied by a risk of blood clots, the development of a heart attack or stroke. Risks are higher in patients suffering from diseases of the cardiovascular system.
  • NSAIDs can not be used in patients undergoing coronary artery bypass graft surgery.
  • The use of NSAIDs can cause sudden bleeding in the digestive tract. In this regard, you should regularly take tests (blood, liver enzymes) to monitor the effect of the drug.

Disease-modifying antirheumatic drugs (BMAP)

Different BMAPP have different principles of action, a positive effect in all cases is achieved the same - the progression of the disease either stops or slows down. The use of BMPA allows to avoid damage to the joints and internal organs.

This group includes preparations: Plakvenil, Arava, Neoral, Imuran, Cytoxan.

Disease-modifying antirheumatic drugs are most often prescribed to patients who are at high risk of irreversible damage to the joints. The use of these medications is indicated for rheumatoid, psoriatic and juvenile idiopathic arthritis.

The main advantage of BMPA is that even with prolonged use, they do not cause addiction and serious side effects.

A significant disadvantage of this group of drugs is a slow action.

This is why, in the treatment of arthritis, BARMP is often used in combination with other drugs that have a faster action, such as NSAIDs, corticosteroids, etc.

Application of BMPAR: it is important to know

  • BMPARs are slow enough, sometimes it takes weeks or even months of treatment to get the first tangible effects.
  • Before you start taking BMAP, be sure to notify your doctor about infectious diseases, if any, at the time of treatment.

    If during the treatment there are signs of infectious diseases (fever, sore throat, painful urination, etc.), immediately consult a doctor.

  • Do not use these medications in patients with hypertension, liver and kidney disease, as well as after vaccination.

Preparations-biological agents

Biological agents (biological response modifiers) are medicines obtained by genetic engineering from living organisms (viruses, genes or proteins).

The most popular biological agents prescribed for arthritis are Actemra, Orencia, Rituximab, Simponi, and others.

Principle of operation

The task of these drugs is to stimulate the body's natural reaction to infection or disease.

The purpose of biological agents that have entered the body are proteins, cells and intercellular communication routes, responsible for the symptoms and destructive effect of rheumatoid and other types of arthritis. These drugs work in one of the following ways:

  • block extracellular protein (tumor necrosis factor), which is produced by white blood cells and causes inflammation of the joints;
  • block white blood cells (B-lymphocytes) that produce antibodies and are present in the body of patients with arthritis in large numbers;
  • block proteins involved in the development of inflammatory processes in the joints;
  • suppress the activation of white blood cells (T-lymphocytes), thereby interrupting the chain reaction leading to the development of inflammation.

Application of biological agents: it is important to know

The use of biological response modifiers, like any other medication, entails certain risks:

  • When treating arthritis with these agents, the risk of developing infectious diseases increases. If there are signs of infection during the treatment period, the patient should immediately consult a doctor.
  • Before starting treatment, a patient should be examined for tuberculosis and other infectious diseases.
  • During the treatment, vaccination is not allowed.

Corticosteroids are medications that mimic the action of the hormone cortisol, which is naturally produced in the body by the adrenal glands. Cortisol has an effect on various systems of the body, including the immune system.

This group includes Celeston, Prednisolon, Diprospan, Metipred, and others.

Operating principle

Corticosteroids lower the level of prostaglandins and disrupt the interaction between certain white blood cells (T and B lymphocytes) involved in the immune response. Due to this, corticosteroids control the inflammatory processes.

Medicines are produced in various forms: tablets, medicines, sprays, drops, injections, ointments, etc. They act quickly and are often prescribed to patients suffering from arthritis and related diseases.

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Compared with NSAIDs, corticosteroids have a more potent anti-inflammatory effect, and these medicines are simply irreplaceable for autoimmune diseases, when it is necessary to suppress the immune response organism.

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However, due to this action the body becomes more vulnerable to infections - this is the main drawback of these funds.

Corticosteroids: it's important to know

Drugs in this category can be used both separately and in combination with other medicines. Remember:

  • You can not independently change the dose of corticosteroids, otherwise it can lead to a decrease in the natural hormone cortisol to a dangerous level.
  • Dose reduction should be gradual to allow the adrenal glands to adapt to changes.
  • Admission corticosteroids for a long time in low doses is often prescribed for rheumatoid arthritis, but the doctors debate about the benefits and side effects of such treatment have not abated until now.

What is better to treat arthritis?

Appoint a suitable preparation, correctly calculate the dosage and make a chart of taking the medicine only the doctor can.

Conclusion

A huge variety of medicines to alleviate the symptoms and therapy of arthritis allows to select the optimal treatment regimen for each patient, taking into account all the specific features of the specific of the situation.

If one method is not suitable, you can try another one or combine the preparations of different groups.

The most important conditions for the successful treatment of an ailment are reliable information about the state of the organism (features functioning of certain organs, the presence or absence of disease), a well-designed treatment regimen and the correct dosage of drugs.

A source: http://SustavZdorov.ru/artrit/preparaty-dlya-lecheniya-114.html

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