Argosulfan is an antiseptic and disinfectant in the form of a cream.
Its main purpose is to accelerate the healing of wounds, treat and prevent their infection, reduce pain, and prepare a wound for skin transplantation.
On this page you will find all information about Argosulfan: the full instructions for use on this medicinal medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied ointment Argosulfan. Want to leave your opinion? Please write in the comments.
Clinical and pharmacological group
The drug with antibacterial action for external use.
Conditions of leave from pharmacies
Available without a prescription.
Price list
How much does Argosulfan cost? The average price in pharmacies is at the level of320 rubles.
.Form of issue and composition
Argosulphan ointment 2% is produced for external application in the form of a homogeneous soft mass of white or slightly pinkish or gray hue.
- In 1 g of ointment contains active ingredient sulfatiazole silver in an amount of 2 g.
- Additional substances: sodium hydrogenphosphate, potassium dihydrogenphosphate, water for injection, alcohol cetostearyl, liquid paraffin, methylhydroxybenzoate, glycerol, white petrolatum, propylhydroxybenzoate, sodium lauryl sulfate.
In aluminum tubes of 15 and 40 g.
Pharmacological effect
Argosulfan refers to antibacterial drugs for topical application.
- Silver ions in the composition of the ointment stop the division and growth of bacteria due to the fact that they bind to the DNA of the microbial cells. Also, silver ions reduce the sensitizing properties of sulfonamide.
- Silver salt (sulfatiazole) in its composition promotes the inhibition of dihydropteroate synthetase, which leads to a halt in the synthesis of dihydrofolic acid and its active metabolite - tetrahydrofolic acid. The latter participates in the synthesis of pyrimidines of the microbe cell and the synthesis of purines.
- The minimum solubility of silver salt helps maintain a stable level of drug concentration in the wound for a long time. Resorption of the drug is minimal, no toxic effect was observed.
Indications for use
The use of Argosulfan is recommended for burns of varying severity and different genesis (including thermal, solar, radiation, chemical, caused by the action of electric current and others), as well as frostbite. In addition, Argosulfan is effective in the treatment of pressure ulcers, trophic ulcers of the legs, including those caused by chronic venous insufficiency, blood supply disorders in diabetes mellitus, erysipelas and obliterans endarteritis.
It is advisable to use the cream in the treatment of purulent wounds, minor domestic injuries (cuts and abrasions), infected dermatitis, complicated impetigo, microbial eczema, streptostafilodermia, simple contact dermatitis.
Contraindications
Argosulfan is contraindicated in hypersensitivity to sulfatiazole and other sulfonamides, as well as with congenital deficiency of glucose-6-phosphate dehydrogenase. Due to the risk of developing "nuclear" jaundice, ointment is not used to treat newborns, premature infants and infants for up to two months.
Application in pregnancy and lactation
According to studies that have been conducted for drugs with silver sulfatiazole content, it does not have any negative effect on the fetus. However, use of Argosulfan Ointment during pregnancy is recommended only in case of emergency (for example, if the surface of the burn exceeds 20% of the body surface).
During breastfeeding, the drug is contraindicated.
Instructions for use Argosulfan
In the instructions for use, it is indicated that Argosulfan ointment is applied topically both in an open manner and in the form of occlusive dressings.
- After cleansing and surgical treatment with the observance of sterility conditions on the wound, apply the drug layer 2-3 mm thick 2-3 times / day. The wound should be covered with cream during treatment. If part of the wound opens, you need to apply the cream additionally.
- The cream is applied until the wound is fully healed or until the skin is transplanted. If, as a result of the application of the cream to infected wounds, exudate appears, before the repeated application of the cream, the wound should be rinsed with 0.1% aqueous chlorhexidine solution or other antiseptic.
The maximum daily dose is 25 g. The maximum duration of treatment is 60 days.
Side effects
In rare cases, there may be a burning sensation in the place of application of the cream. In patients, skin allergic reactions may occur. The use of Argosulfan for a long time can provoke changes in the blood, desquamative dermatitis, characteristic of systemic sulfonamides (leukopenia).
special instructions
Caution should be given to patients who are in a state of shock, with extensive burns due to the impossibility of collecting a full allergological anamnesis.
For hepatic and / or renal insufficiency, the concentration of sulfatiazol in serum should be monitored.
The drug does not limit the psychophysical ability, the ability to drive vehicles and maintain machinery in motion.
Drug Interactions
It is not recommended to use Argosulfan in combination with other topical drugs.
Antibacterial action of Argosulfan reduces folic acid and p-aminosalicylic acid.
With simultaneous treatment with cimetidine and Argosulfan increases the risk of developing leukopenia.
Reviews
We picked up some feedback from people about the drug:
- Maksim.Norm cream, I'm happy. Excellent heals wounds, abrasions, cuts and stuff. Particularly pleasing to me is its antibacterial property, thanks to which it is calm even for the "natural" wound-cuts that occur in the street / country / nature, because The cream protects the wound from getting into it infection.
- Svetlana. This cream was advised to me by a pharmacist when I went to a pharmacy after an unsuccessful fall from a bicycle. Immediately washed the abrasion, the blood stopped, bought Argosulfan and smeared directly on the drugstore on his knees, bandages were bandaged. Cream thanks to silver ions in the composition has antibacterial action and accelerates healing. I think that in the medicine cabinet this cream is always useful.
In medical practice, the cream has established itself as an excellent tool in the treatment of large area burns. Thematic forums and medical portals, where ordinary patients share their impressions, contain only positive reviews about Argosulfan. Young mothers also leave their feedback about ointments, and point to its good tolerability by young children, high efficiency in the treatment of abrasions, cuts and wounds.
Analogues
Analogues of the drug according to indications for use are:
- Cream Argdin Bosnachek;
- Ointment Sulfargin;
- Cream Dermazin;
- Ointment and liniment Streptocide.
Before using analogues, consult your doctor.
Storage conditions and shelf life
List B. The drug should be stored out of the reach of children at a temperature of no higher than 25 ° C; Do not freeze. Shelf life - 2 years.
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