Arkoksia: instructions for use and analogues of medication

"Arkoksia reviews of doctors. Anti-inflammatory drug "Arkoksia price, analogues and contraindications

Unfortunately, a variety of inflammatory diseases are very common, and it is likely that at least once in a lifetime every person has encountered such a problem.

Naturally, there are various drugs that help stop the development of the inflammatory process. And the medicine "Arkoksia" is considered quite good.

The doctors' comments about this remedy are positive, as it really helps to cope with the disease, to eliminate pain and fever.

So what is included in its composition? In what cases can it be taken? Are there any contraindications? Many patients are interested in answering these questions.

Composition and form of the drug

Two-convex tablets of an interesting apple-like shape, covered with a film membrane - it is in this form that the drug "Arkoksia" is released. Injections, solutions for oral administration, gels, ointments - these forms of the drug do not exist.

The main active component of the drug is etorikoksib. By the way, in the pharmacy are sold tablets of different colors depending on the amount of active substance - they can be green (60 mg etorikoksiba), white (90 mg) or light green (120 mg).

Naturally, some auxiliary components are present in the composition: magnesium stearate, calcium hydrogenphosphate, croscarmellose sodium and microcrystalline cellulose.

Tablets are placed in convenient blisters for seven pieces. In the pharmacy you can buy packages with one or three such blisters.

Basic pharmacological properties

This medicine belongs to the group of non-steroidal anti-inflammatory drugs.

Etorikoksib is a substance that selectively inhibits COX-2, which in turn inhibits the synthesis of prostaglandins, blocking the development of the inflammatory process.

The drug "Arkoksia" also has a pronounced analgesic and antipyretic effect, but it does not affect the mucosa of the digestive system and the functioning of platelets.

After taking the medicine, it is quickly absorbed, its bioavailability is 100%. The maximum concentration in the blood is observed after 1 hour.

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The active component binds to plasma proteins by more than 92%.

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It is excreted from the body mainly through the kidneys, and only 20% of the substances are released with a fecal mass.

Indications for use

In what cases is it expedient to take the medicine "Arkoksia"? Its application is wide enough, as it provides a quick analgesic effect, and also allows to eliminate the inflammatory process.

Nevertheless, most often the drug is prescribed to patients suffering from osteoarthritis and rheumatoid arthritis. Indications for use are also pain caused by gouty arthritis and ankylosing spondylitis.

In some cases, pills are recommended for people who have recently undergone a dental operation.

Medication "Arkoksia" (tablets): instructions for use and dosage

In no case should you use this medication yourself. Only the doctor can prescribe and tell about how to properly take the drug "Arkoksia" (pills). The instruction contains only general recommendations.

Dosage, as a rule, depends on the patient's condition and the variety of his problem. For example, with osteoarthritis, it is most often recommended to take one tablet at a dosage of 60 mg per day, regardless of food intake.

Nevertheless, the maximum allowable period of treatment is 8-10 days, after which the reception should at least temporarily stop.

With care, the drug is prescribed for people suffering from liver failure - the daily dose in such cases should not exceed 60 mg.

Are there any contraindications?

Immediately it is worth saying that this drug can not be taken to all categories of patients. The drug has contraindications, with a list of which must be read before the reception:

• hypersensitivity to the components of the drug, as well as other non-steroidal anti-inflammatory drugs, especially in patients suffering from bronchial asthma and polyposis of the nose;
• erosive and ulcerative lesions of the mucosa of the digestive tract, gastrointestinal bleeding;
• inflammatory bowel diseases, including ulcerative colitis and Crohn's disease;
• bleeding disorders, including hemophilia;
• severe heart failure;
• severe forms of renal and hepatic insufficiency;
• severe ischemic heart disease;
• period after aortocoronary shunting;
• persistent arterial hypertension;
• children's age (the drug is not prescribed for children under 16 years of age);
• pregnancy, lactation, as well as the period of pregnancy planning.

The drug also has some relative contraindications, in which therapy is possible, but only with the constant supervision of the attending physician.

With care, the drug is prescribed for patients suffering from fluid retention in the body, as well as with severe physical illnesses, hypertension and diabetes mellitus.

The medicine also can not be combined with alcohol.

Side effects

Many patients ask the question of what complications can lead to the drug "Arkoksia." The doctors' testimonies indicate that patients taking pills rarely complain about any worsening.

Nevertheless, adverse reactions are possible. For example, against the background of therapy, an allergic reaction may occur, sometimes even anaphylactic shock.

Some patients noted the appearance of nausea, abdominal pain, diarrhea, bloating, belching, dry mouth.

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Possible side effects also include headaches, weakness, confusion, sleep disorders, anxiety, concentration problems, depressive conditions, blurred vision, vertigo, noise in the ears.

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Sometimes there are violations of the respiratory system, in particular cough, as well as nosebleeds.

The drug can act on the cardiovascular system, causing an increase in pressure, palpitation, extremely rarely - stagnation, circulatory disorders of the brain, hypertensive crisis, heart attack myocardium.

In some patients, the medicine increases the likelihood of developing infectious diseases of the respiratory and digestive systems.

Overdose: symptoms and treatments

Is an overdose of the drug Arkoksia possible? The doctors' comments and statistical studies indicate that officially such cases were not registered.

Even a single dose of 500 mg of active substance, as well as the use of small doses of the drug for three weeks, are not accompanied by serious complications.

Overdose can exacerbate the present side effects from the cardiovascular and digestive systems. Therapy in this case is symptomatic and is aimed at eliminating existing violations.

Interaction with other drugs

With the simultaneous administration of "Arkoksia" and anticoagulants, you need to carefully monitor the international normalized relationship (INR) - ratio of prothrombin time of this patient to mean prothrombin time - especially in the first few days of therapy.

Simultaneous reception of this drug with high doses of acetylsalicylic acid increases the risk of ulcerative lesions of the mucosa of the digestive tract. Simultaneous therapy with tacrolimus and cyclosporins increases the likelihood of developing nephrotoxicity.

The drug can interact with some oral contraceptives, increasing the risk of developing thromboembolism, so before starting therapy, be sure to tell your doctor about the hormones you take - probably, they will need replace.

Tablets "Arkoksia analogues and substitutes

Not every patient for one reason or another is suitable for this drug. Therefore, many people are interested in the question of what can replace the drug "Arkoksia." Analogues of this tool exist, and there are quite a few of them.

For example, if it is an analgesia, then such non-steroidal anti-inflammatory drugs are considered quite popular, as "Ibuprofen "Nurofen "Diclofenac" (by the way, it is also available in the form of a gel for external use), Ketonal and many others.

And if you suffer from osteoporosis and other diseases of the musculoskeletal system, then you can choose another substitute.

"Arkoksia" is often replaced by such drugs as "Ostalon "Alendros "Ost "Lindron". But remember that only an attending physician can choose an analogue.

Do it yourself categorically is contraindicated.

How much is the medicine?

Many patients are interested in the question of how much the drug "Arkoksia" costs. The price, of course, will depend on some factors. In particular, it is necessary to take into account the city of residence, the price policy of the pharmacy, the manufacturing company, etc.

So how much will the medicine "Arkoksia" cost? The price of packing of seven tablets of 60 mg ranges from 350 to 450 rubles. Three blisters will cost about 1100 rubles.

Dosage is another factor on which the cost of the drug "Arkoksia" depends. Tablets of 90 mg cost about 550 rubles for seven pieces. For a package of three blisters, you need to pay about 1300-1400 rubles.

Seven tablets with 120 mg of active ingredient cost about 700 rubles.

Feedback from specialists and patients

Of course, many patients are interested in the question of what experts think about the drug "Arkoksia." The doctors' reviews are mostly positive.

The fact is that the pills really relieve the pain. Moreover, they inhibit the development of the inflammatory process and help normalize body temperature with fever.

In addition, the tablets are not as destructive to the liver and digestive system as some other non-steroidal anti-inflammatory drugs.

Patients for the most part also respond positively to the drug. This remedy actually facilitates the condition and relieves soreness, while it works practically throughout the day.

Most often, one tablet per day is enough, which is very convenient.

Some people have contraindications or side effects, but it is worth noting that the reaction of the body to these or other medications is individual.

The disadvantages include high cost, which not everyone has to afford. On the other hand, one blister, as a rule, is enough for the entire course of treatment.

A source: http://.ru/article/190770/arkoksia-otzyivyi-vrachey-protivovospalitelnoe-sredstvo-arkoksia-tsena-analogi-i-protivopokazaniya

Cheap analogs and substitutes for the drug arkoksia: a list with prices

Arkoksia - an anti-inflammatory drug from the United States. Produced in the form of tablets of varying dosage.

The drug has a long list of contraindications, they must necessarily be studied before taking the tablets.

The main thing in this list is the age of patients under 16 and a complete ban for pregnant and lactating mothers.

Analogues cheaper than arkoxia have another active substance.Only one import substitute with a similar active substance is known.

The price for it is similar.

Other analogues are produced in the territories of different states: Russian, Belarusian, Ukrainian and imported analogues.

The price of tablets depends on the dosage of the active ingredient, so the smallest dosage costs 300 rubles, and the highest dosage is twice as expensive as 600 rubles.

Analogues of Russian production

Domestic drugs have been known for many generations, are inexpensive and have a noticeable effect.

Name of the preparation	Average price in rubles	Characteristic
Diclofenac	9-20	In addition to Russia, it is manufactured in Serbia, Germany, Romania. Has a triple action: anesthetizes, lowers the temperature and has an anti-inflammatory effect. The cheapest anesthetic drug. It's cheaper to find.
Dilaxa	240-250	Eliminates pain in the locomotor apparatus. Helps with fever.
Arthrin	200-230	Ointment hondoprotector. Relieves inflammation and relieves pain.
Nimesulide	42-50	Non-steroidal anti-inflammatory drug. In addition to diseases of the skeleton, it helps with dental pain, during the period of PMS or from a headache.
Arthrofoon	250-260	Suitable both during the remission of the disease, and during periods of exacerbation. It is not prescribed for children under 18 years. Released without a doctor's prescription.
Arthrovitis	128-134	Inexpensive drug from the category of dietary supplements based on natural components. Improves the condition of the musculoskeletal system for chronic joint diseases. The form of production is a drop.

Ukrainian substitutes

Replacement for a cheap analogue of Ukrainian production is the least expensive of all. Tablets are inexpensive, and their quality is checked by time.

1. Ibuprofen. It is produced not only in Ukraine, but also in Belarus and Serbia. The drug is available in the form of tablets, as well as ointments and gel, candles and a special kind for children. In children, the drug reduces the temperature for various types of diseases and as an anesthetic. Tablets are cheap from 20 to 85 rubles.

   Syrup is not more expensive than 100. Ointment and gel are cheaper 30 and 60 rubles, respectively. Baby candles cost about 65 rubles.

2. Chondroitin extra plus Rodovit. The drug is made of natural ingredients, supplemented with vitamins. In addition to facilitating the condition in diseases of the musculoskeletal system, it protects the joints from age-related changes while preserving their mobility.

   It costs about 200 rubles. The best of natural preparations and inexpensive in its sector.

3. Chondroetin forte. Returns the joints and bone tissues a healthy state. Reduces inflammation. Produced in the form of tablets. It costs 450 rubles.
4. Chondroflor. Anti-inflammatory and analgesic. It costs 280 rubles.
5. Chondroitin with glucosamine. Restores bone-cartilaginous tissue, relieves pain and inflammation. Promotes the development of its own hyaluronic acid in deep tissues. It costs 550 rubles.

Belarusian generics

Close substitutes or generics of Arkoksia are produced in Belarus by the "Belmedpreparaty" plant. This is an enterprise with a long history, a guarantee of quality and low prices. Some types include the table below.

Name of the preparation	Average price in rubles	Characteristic
Celecoxib	500-800	The medicine blocks the development of inflammatory processes in the body. Relieves fever relieves pain.
Dimexide-Belmed	26-40	The application of the device is simple: the liquid is rubbed into the area of ​​pain, the components freely penetrate through the tissues to the epicenter of pain and reduce its intensity, an anti-inflammatory and antimicrobial.
Dimexide, gel 25%, 50%	150-160	Anti-inflammatory drug. Promotes more complete penetration of other drugs to the source of pain and inflammation.
Xondrocoid	335-350	Anti-inflammatory ointment. Corrects the metabolism of bone or cartilaginous tissue. Reduces pain.

Other foreign analogs

Cheap analogues of the drug among imported products are more difficult to find, often domestic products are cheaper. But the price justifies the quality and effectiveness of medicines. Imported medicines are modern synonyms.

The composition of the drug forms the components with minimal harm and maximum benefit.

Below is a list of the most common:

• Exciseff. It is produced in Spain and the Netherlands. Contains also active substance, as arkoksia. It is forbidden to use till 16 years. It costs 300-600 rubles.
• Denebol. Manufacturers of India and the United Kingdom. Tablets cost from 250 to 610 rubles. The drug is produced in the form of a gel, costs 187 rubles.
• Dinastat. Manufactured in USA. Anti-inflammatory and antirheumatic means that affect the condition of the musculoskeletal system. The drug is available in powder form for the preparation of intramuscular injections. The medicine is not cheap - about 6000 rudders.
• Ranseleks. The manufacturer is registered in India. Indications for appointment: osteoarthritis or rheumatoid arthritis. Side effects from taking this medication do not practically arise. It costs from 90 to 140 rubles.
• Celebrex. The factory is located in Germany. The drug combines anti-inflammatory, antipyretic and analgesic effect. Packing with 10 capsules costs 400 rubles.

Arkoksia is a relatively inexpensive drug with a wide spectrum of action. Do not forget that it is prohibited for use in pregnancy, during breastfeeding, children under 16 years of age and in the presence of certain diseases.

If this is the case, you can easily select a suitable analog. What can replace arkoksia doctor or pharmacist.

A source: https://LadyTrand.ru/lekarstva/arkoksia-analogi.html

What helps Arkoksia? Instructions for use on tablets

The medicine of analgesic, antipyretic and anti-inflammatory action - tablets Arkoksia.

What helps this selective inhibitor of COX-2, NSAIDs (non-steroidal anti-inflammatory drug)? The drug Arkoksia instructions for use suggest taking with arthritis, spondylitis, pain.

Composition and form of release

Medication Arkoksia is a tablet covered with a turquoise shell, biconvex, globular, with the inscription "ACX 30" on one side and the inscription "101" on the other.

Tablets Arkoksia 60 mg, 90 mg, 120 mg sold for 7 pieces in a blister. The drug with a dosage of 30 mg is available in 2, 4, 7 or 14 pieces in a blister pack.

Tablets Arkoksia, from which the drug helps with pain, contains the active substance: etorikoksiba - 30, 60, 90 or 120 mg, depending on the dosage. Excipients are: calcium hydrogen phosphate, microcrystalline cellulose, croscarmellose sodium, magnesium stearate.

Pharmacological properties

Arkoksia's medication, instruction for use reports this, is a non-steroidal anti-inflammatory drug (NSAID).

The selective inhibitor of COX-2, at therapeutic concentrations, blocks the formation of prostaglandins and has anti-inflammatory, analgesic and antipyretic effects.

Selective oppression of COX-2 is accompanied by a decrease in the severity of clinical symptoms associated with inflammatory process, with no effect on the function of platelets and the mucosa of the gastrointestinal tract. Etorikoksib (the active substance of the preparation Arkoksia) has a dose-dependent effect of COX-2 inhibition, without affecting COX-1 when applied at a daily dose of up to 150 mg.

The agent has no effect on the production of prostaglandins in the mucous membrane of the stomach and at the time of bleeding. In the conducted studies, there was no decrease in the level of arachidonic acid and platelet aggregation caused by collagen.

Arkoxia tablets: what helps the medicine

Indications for use include:

• acute gouty arthritis;
• symptomatic treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, accompanied by inflammatory symptoms and pain;
• short-term therapy of moderate acute pain after dental operations.

The decision to appoint an electoral blocker for COX-2 should be made, taking into account all the individual risks for the patient.

Contraindications

Absolute (instruction prohibits reception):

• intolerance to acetylsalicylic acid and other NSAIDs;
• children and adolescents under 16;
• During pregnancy and breastfeeding; exacerbation of inflammatory bowel diseases (ulcerative colitis and Crohn's disease);
• severe renal failure (creatinine clearance less than 30 ml / min), confirmed hyperkalemia, progressive kidney disease;
• active gastrointestinal, cerebrovascular or other bleeding;
• persistently persistent high blood pressure with uncontrolled hypertension;
• hypersensitivity to any of the components of the drug Arkoksia, from which the tablets can cause allergies;
• disorders of blood clotting (including hemophilia);
• Clinically expressed ischemic heart disease, cerebrovascular disease and peripheral arterial disease, the period after CABG (coronary artery bypass grafting);
• severe heart failure;
• incomplete or complete combination of the following diseases (including in the history): recurrent nasal polyposis or paranasal sinuses, bronchial asthma and
• erosive and ulcerative lesions of the mucosa of the duodenum or stomach;
• severe hepatic insufficiency, liver disease in the active phase.

Relative (tablets Arkoksia instructions for use require drinking with caution):

• long-term use of NSAIDs;
• severe physical illness;
• the presence in the anamnesis of data on the development of ulcerative lesions of the gastrointestinal tract and Helicobacter pylori infection;
• arterial hypertension;
• diabetes;
• edema and fluid retention;
• dyslipidemia or hyperlipidemia;
• concomitant therapy with antiaggregants, glucocorticosteroids, anticoagulants and selective serotonin reuptake inhibitors;
• renal failure (with creatinine clearance less than 60 ml / min);
• smoking;
• frequent use of alcohol;
• elderly age.

Arkoksia preparation: instructions for use and dosing regimen

Tablets are taken orally, regardless of food intake, with a small amount of water. With osteoarthritis, the recommended dose is 60 mg 1 time per day.

The daily dose for osteoarthritis should not exceed 60 mg. In rheumatoid arthritis and ankylosing spondylitis, the recommended dose is 90 mg once a day.

The daily dose for rheumatoid arthritis and ankylosing spondylitis should not exceed 90 mg.

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In acute gouty arthritis, the recommended dose in the acute period is 120 mg once a day. The daily dose for acute gouty arthritis should not exceed 120 mg.

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The duration of use of the drug at a dose of 120 mg is not more than 8 days.

A minimum effective dose should be used with the minimum possible short course. The average therapeutic dose for pain is only 60 mg once. Acute pain after dental operations: the recommended dose is 90 mg once a day.

In the treatment of acute pain, the drug Arkoksia should be used only in the acute symptomatic period, limited to no more than 8 days.

In patients with hepatic insufficiency (5-9 points on the Child-Pugh scale), it is recommended not to exceed the daily dose of 60 mg.

Side effect

• anaphylactic / anaphylactoid reactions, including a marked decrease in blood pressure and shock;
• pain in the chest;
• cough;
• nose bleed;
• a taste disorder;
• tides;
• bronchospasm;
• diarrhea;
• congestive heart failure;
• weakness;
• atrial fibrillation;
• hypertensive crisis;
• eructation;
• edema, fluid retention;
• hives;
• swelling of the face;
• confusion of consciousness;
• noise in ears;
• depression;
• increased peristalsis;
• conjunctivitis;
• increased blood pressure;
• Gastrointestinal ulcers (with bleeding or perforation);
• irritable bowel syndrome;
• infection of the upper respiratory tract, urinary tract;
• gastritis;
• itching;
• arthralgia;
• dryness of the oral mucosa;
• influenza-like syndrome;
• headache;
• rash;
• blurred vision;
• bloating;
• drowsiness;
• anxiety;
• Stevens-Johnson syndrome;
• renal failure, usually reversible with withdrawal of the drug;
• constipation;
• dyspnea;
• palpitation;
• Lyell's syndrome;
• dizziness;
• hallucinations;
• muscle cramps;
• esophagitis;
• ulcers of the oral mucosa;
• ulcer of the mucous membrane of the stomach or duodenum;
• changes in appetite;
• nausea, vomiting;
• sensitivity disorders, incl. paresthesia / hyperesthesia;
• impaired cerebral circulation;
• flatulence;
• sleep disorders;
• weight gain;
• myalgia;
• leukopenia, thrombocytopenia;
• dyspepsia;
• epigastric pain;

Drug Interactions

With the simultaneous use of arkoksia with warfarin or similar drugs at the beginning of therapy and with each change dosage regimen should monitor prothrombin time and INR (international normalized relations).

When co-administered with ACE inhibitors, it is possible to weaken the hypotensive effect of ACE inhibitors. With violations of kidney function, this combination can lead to further aggravation of functional kidney failure. With the simultaneous use of Arkoksia:

• with cyclosporine and tacrolimus, the risk of nephrotoxicity of these drugs increases;
• with acetylsalicylic acid in low doses - it is possible to increase the frequency of ulcerative lesions of the gastrointestinal tract;
• with lithium preparations - an increase in the plasma concentration of lithium can be observed;
• with methotrexate - possible manifestation of toxicity of methotrexate (especially when using Arkoksia in a dose of 120 mg);
• with oral contraceptives (especially ethinyl estradiol) - increases the concentration of ethinyl estradiol;
• with digoxin - possible overdose of digoxin;
• with rifampicin - the plasma concentration of ethoricoxib decreases;
• with antacids and ketoconazole - there is no clinically significant interaction.

special instructions

Admission Arkoksia requires constant monitoring of blood pressure.

All patients with this drug should be monitored for blood pressure within the first 14 days of treatment.

It is also recommended to regularly monitor the indicators of kidney and liver.

If the level of hepatic enzymes is increased three times or more relative to the normal level, the drug must be canceled. It is forbidden to use the drug together with other non-steroidal anti-inflammatory drugs.

Given the increased risk of side effects due to increased duration of admission It is necessary to regularly assess the need to extend the use of Arkoxia and the possibility of reducing dose.

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The shell of the drug contains lactose in small amounts - this should be taken into account when appointing Arkoksia patients with intolerance to lactose.

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During treatment, special care must be taken when driving vehicles and engaging in potentially dangerous activities that require concentration of attention and speed of psychomotor reactions. Persons who have a history of episodes of dizziness, weakness, should refrain from such activities.

Use in children, during pregnancy and lactation

Contraindicated in children and adolescents under the age of 16 years. The drug Arkoksia during pregnancy and lactation can not be taken. The use of the drug may adversely affect female fertility and is not recommended for women planning pregnancy.

Analogues of Arkoxia medication

There are no structural analogs for the active element. The only analogue of Arkoxia containing ethoricoxib is Exinef (Spain / Netherlands).

Preparations having a similar structure and effects of the active substance: Denebol, Dinastat, Renseleks, Celebrex and others.

The price of analogues in most cases is lower than the price of Arkoksia.

To the means for the treatment of arthrosis are analogues:

• Aktasulid.
• Brufen.
• Diclofenac.
• Diklobene.
• Donalgin.
• Diprospan.
• Sanaprox.
• Piroxicam.
• Diclofen.
• Nimesil.
• Rumalon.
• Movasin.
• Rheumatic Gel.
• Glucosamine sulfate 750.
• Arthra.
• The Dolgit.
• Fllolid.
• Kartilag Vitrum.
• Miolastan.
• Butadione.
• Dexazone.
• Dimexide.
• Ibuprofen.
• Artradol.
• Dicluberl.
• Mesulide.
• Chondrolon.
• Naproxen.
• Tenikam.
• Orthophene.
• Dicclore.
• Ketonal.
• Tenoktil.
• Voltaren Emulgel.
• Apranax.
• Cefephecon.
• Feloran.
• Aulin.
• Fastum gel.
• Arthrothec.
• Alflutop.
• Cigapan.
• Zinaksin.
• Coxib.
• The Unium.
• Indomethacin.
• RONIDASE.
• Hondramine.
• Sabelnik Evalar.
• Believed.
• DONA.
• Triamsinolone.
• An arthrovitis.
• Dexamethasone phosphate.

Price

Tablets Arkoksia 120 mg in Moscow you can buy for 487 rubles (7 pieces). The price of the drug in Kiev is 207 UAH, in Kazakhstan - 9845 tenge (28 tablets of 60 mg). In Minsk, pharmacies sell the medicine for 16-25 bel. rubles.

Reviews

Medical portals and forums abound with reviews of Arkoksia.

In general, the reviews of doctors and patients on these tablets are the same: almost 100% effectiveness when using the drug and a fairly high number of reports of the occurrence of side effects. Also, many complain about the rather high cost of the drug.

"I was taking sciatic nerve with inflammation, the effect is stunning. After a week of treatment with the Dicloberla et al.

drugs, exhausted from the pain, got to a good neurologist who appointed this drug. For 3 days the pain disappeared. Do not believe.

So much took injections, but there was no effect. And these pills helped. "

"I was prescribed this drug for pain in the spine. Anesthetizes very well. One tablet a day is enough.

This drug has no negative effect on the liver, compared with other drugs. Although here you should also read the instructions. There are contraindications.

If the painkillers take it often, less impact on the liver is very important. "

"I had an inflammation of the tendons. After taking the first pill, I did not feel any relief, but

after the 3rd the result was. Tablets are very strong, and a day you can drink only 1-nu. In the package, 10 tablets and this is enough to relieve the inflammation in 10 days. "

"Rheumatologist appointed Arkoksia for the treatment of arthritis. On the second day of admission, there was a side effect - severe nausea. This symptom was not associated with taking the medication, and on the third day after taking the pill, the nausea returned. Now I drink polysorb. "

"There is no drug. The effect is zero. This is noted by pharmacists and the response of patients. The drug is not worth the money for which it is offered - 14 tablets per 2 thousand rubles. There are cheaper and very effective drugs. "

A source: http://remedy.ucoz.ru/index/tabletki_arkoksia_ot_chego_pomogaet_instrukcija_po_primeneniju_analogi_cena_otzyvy_60_90_120_mg/0-574

Arkoksia: instructions for use

Arkoksia - a drug that has an anti-inflammatory, analgesic, antipyretic effect in the treatment inflammatory diseases of the joints and intraarticular tissues, accompanied by degenerative changes and dystrophic phenomena.

Arkoksia is an inhibitor of cyclooxygenase type 2 (COX-2) selective action. COX-2 is responsible for the formation and distribution in the body of active substances that cause pain, inflammation and fever.

The effectiveness of the drug has been proved by numerous scientific studies, in which it is established:

• the use of 60 mg of the drug in the management of pain syndrome in patients with osteoarthritis significantly improves the patient's condition;

• 90 mg of active ingredient Arkoxy - etorikoksib reduce pain, signs of inflammation and facilitate the mobility of the joint in persons suffering from rheumatoid arthritis or ankylosing spondylitis;

• with an acute attack of gouty arthritis, 120 mg / day should be used, which significantly alleviates the patient's condition and reduces soreness after 4 hours after the first administration of the drug.

Form of issue

Arkoksia is available in tablets that have the shape of an apple. The surface of the tablets is protected by a film. Depending on the dosage, the tablets have a different color.

Composition

Active substance:

• etorikoksib - tablets 60 mg (green), 90 mg (white), 120 mg (blue-green).

Also, the tablet contains auxiliary substances that ensure its integrity, color and shape.

Indications for use

Arkoksia is appointed to relieve inflammation, reduce the intensity of pain and antipyretic effect in symptomatic treatment:

• Rheumatoid arthritis, polyarthritis, periarthritis;
• acute gouty arthritis;
• osteoarthritis;
• ankylosing spondylitis;
• severe pain syndrome with inflammation of soft tissue diseases;
• pain in injuries, fractures and after surgery.

Contraindications

The drug is contraindicated when:

• hypersensitivity reactions to acting or auxiliary substances that are part of the drug;
• presence in the anamnesis of bronchial asthma, polyps of nasal sinuses and intolerance to NSAIDs;
• the presence of erosions or ulcers of the digestive tract;
• presence of bleeding, inclination to clotting disorder;
• acute inflammation of the intestine (granulomatous enteritis, ulcerative colitis);
• severe cardiac, hepatic, renal failure;
• severe vascular disorders and uncontrolled increase in blood pressure;
• pregnancy and breastfeeding;
• aged less than 16 years.

Dosing and Administration

The dose is selected individually, according to the doctor's prescription. The medicine is taken regardless of the ingestion of food inside. When using it on an empty stomach, the effect manifests itself much faster. Take the pill once a day. The course of treatment should not exceed 8 days.

• with osteoarthritis, the dose can be from 30 to 60 mg, depending on the severity of the symptoms;
• with rheumatoid arthritis and ankylosing spondylitis take 90 mg;
• to relieve pain and inflammation in acute gouty arthritis - 120 mg;
• when acute pain is prescribed 90 or 120 mg, depending on the severity of the pain syndrome;
• when chronic pain is prescribed 60 mg.

With heart or vascular diseases, treatment courses are prescribed as short as possible to reduce the risk of complications.

When appointing Arkoksia, older people do not need to adjust their doses.

Side effects

In application, the following negative effects are possible:

• neurological: headache, dizziness, general weakness and lethargy, drowsiness. Sometimes there is a noise in the ears. A feeling of anxiety, a depressed state, a decrease in attention can develop. Rarely are there hallucinations or confusion;

• sensory organs: a violation of taste, vision, sensitivity, possible conjunctivitis;

• Cardiovascular: increased heart rate, increased arterial pressure, impaired cerebral circulation, heart failure, heart attack, hypertensive crisis;

• hematopoiesis: a decrease in hematocrit and hemoglobin, the number of leukocytes and platelets;

• respiratory: cough, the appearance of dyspnea, nosebleeds, respiratory infections, bronchospasm;

• digestive: dyspeptic phenomena, accompanied by nausea, vomiting, diarrhea, flatulence. Possible pain in the abdomen, increased levels of liver transaminases, constipation, dry mouth, changes in appetite, inflammation of the gastrointestinal tract (gastritis, esophagitis, gastroenteritis, hepatitis), the formation of the gastrointestinal ulcer, the development of irritable bowel syndrome, the appearance of ulcers on the mucosa mouth;

• urinary excretion: proteinuria, urinary tract infection, renal failure;

• musculoskeletal: convulsions, pain in the joints and muscles;

• cutaneous: hemorrhages in the skin or mucous membranes, face swelling, rashes on the skin, accompanied by itching, hives, as well as in isolated cases - a syndrome of exudative erythema, epidermal necrolysis;

• allergic: anaphylactic reactions, including a sharp decrease in arterial pressure, shock;

• other: flu-like syndrome, peripheral edema, fluid retention in the body, chest pain, increase in body weight, azotemia, azoturia, an increase in the level of creatinine, potassium and sodium in the blood, hyperuricemia.

special instructions

• when prescribing the drug, perforation, ulceration or bleeding from the upper parts of the digestive tract is possible, up to a lethal outcome;

• caution should be given to patients taking other non-steroidal anti-inflammatory drugs, especially acetylsalicylic acid;

• in the presence of pathology on the part of the heart or vessels, it is necessary to prescribe the drug in short courses and in the lowest effective dosage, since the use of etorikoksib possible development of thrombotic complications;

• there should be careful monitoring of kidney function in persons prone to impairment of their function, since etorikoksib can reduce renal blood flow;

• when taking medication, fluid retention in the body, the development of edema and hypertension may occur. Therefore, when prescribing a drug for patients with a tendency to such phenomena, it is necessary to observe precautions, pay special attention to control of blood pressure, and in case of deterioration, take appropriate measures until the drug is discontinued and an alternative treatment;

• at possible pathologies of the liver, it is necessary to control the level of transaminases in the blood;

• special attention should be paid to elderly people, if there is a violation of the function of any of the body systems, if there is dehydration in the patient;

• serious skin lesions manifested itself in isolated cases. Anaphylactic reactions and development of Quincke edema are possible, due to which attention should be paid to the presence of allergic reactions in the patient's history to any medication. When the first skin manifestations appear, the medicine should be discarded;

• with caution prescribed when taking warfarin and other oral anticoagulants;

• etorikoksib not recommended when planning pregnancy;

• the composition of Arkoksia includes lactose, as a result of which the drug is contraindicated for persons suffering from its intolerance.

Analogs of Arcoxia

Drugs with the same composition as Arkoksia do not. There are similar preparations with active substance from the group of coxibes:

• Dilax (KRKA-Rus, Russia), Celebrex (Pfizer Pharmaceuticals, Puerto Rico) contain celecoxib. Is issued on 100, 200 mg in capsules. It is used to treat the same pathologies as etorikoksib;

• Dinastat (parecoxib) is available as a lyophilizate for the preparation of a solution for injection (Searle, Puerto Rico). It is used for severe pain syndrome.

Terms and conditions of storage

Shelf life is 3 years. After the expiration of this period, the use of the medicinal product is prohibited. Keep the tablets in a place inaccessible to children, with a temperature range not exceeding 30 degrees.

Arkoksia Price

Arcoxia tablets 60 mg, 7 pcs. - from 355 rubles.

Arkoxia tablets 90 mg, 7 pcs. - from 430 rubles.

Arcoxia tablets 120 mg, 7 pcs. - from 536 rubles.

Estimate Arkoksia on a 5-point scale:

(174, average rating3.0862from 5)

A source: http://bezboleznej.ru/arkoksia