In inflammatory eye diseases, doctors often recommend the use of hydrocortisone ointment. This drug not only eliminates inflammation, but also has anti-allergic effect.
In this article, we will consider in detail the instructions for the use of Hydrocortisone, since this ointment has its own specific features.
Content
- 1Description of the preparation
- 2Pharmacological action and group
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3Indications and contraindications in use
- 3.1In pregnancy
- 3.2To small children
- 4Possible complications caused by the drug
- 5Video
- 6conclusions
Description of the preparation
Ointment for the eyes Hydrocortisone is a synthetic glucocorticosteroid drug used externally for the treatment of inflammatory eye diseases.
This drug has a pronounced anti-inflammatory, anti-edematous, antipruritic and anti-allergic effect.
Hydrocortisone is produced in the form of an ointment (also the preparation can be in the form of a gel or cream), which is packaged in tubes of three and five grams.
The main active ingredient is hydrocortisone acetate (glucocorticosteroid).
One hundred grams of ointment contains one gram of hydrocortisone. Excipients: methylparaben (nipagin), propyl parahydroxybenzoate, stearic acid, lanolin anhydrous, pentaerythritol dioleate (pentol), purified water, medical Vaseline.The drug is suitable for local effects. To do this, for the lower eyelid lay a strip of ointment (about a centimeter). The procedure is carried out two to three times a day. The course of treatment lasts from one to two weeks. If necessary, the doctor can continue therapy with Hydrocortisone.
It should be remembered that during treatment it is necessary to abandon the use of contact lenses. If eye drops are used in parallel, then between their administration and use of the ointment should take at least fifteen minutes.
With special care ointment should be used for glaucoma.It is necessary to constantly monitor the intraocular pressure.
Analog Hydrocortisone - Maxidex.
The line of validity of Hydrocortisone is two years. Keep it at a temperature of five to fifteen degrees.
Pharmacological action and group
Hydrocortisone is a synthetic glucocorticosteroid drug and is used only externally. Ointment has anti-inflammatory, anti-allergic effect.
This drug inhibits the release of cytokines from lymphocytes and macrophages, inhibits the release eosinophils mediators of inflammation, disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, induces formation lipocortin.
Ointment contributes to the reduction of inflammatory cell infiltrates, reduces the migration of leukocytes and lymphocytes to the area of inflammation, reduces the degree of expression of the early immunological response, has an antimetabolic effect and inhibits the formation of connective tissue and scarring.
When the dosage is met, hydrocortisone does not cause side effects.
Hydrocortisone poorly penetrates into the intraocular fluid through the orbit. The ointment can enter only the epithelium of the mucous membrane and the epidermis, it can also be absorbed into the bloodstream in small amounts and subsequently have systemic action.
Metabolic processes occur in the epithelium of the mucosa and epidermis.After absorption, the drug enters the systemic circulation and is further metabolized in the liver. In the blood, the active substance binds to transcriticin and albumins.Metabolites of this drug are excreted by the intestines and kidneys.
Indications and contraindications in use
Indications for use Hydrocortisone:
- Allergic diseases of the eyes (dermatitis of the eyelids, conjunctivitis, keratoconjunctivitis, blepharitis).
- Inflammatory processes of the anterior part of the eye, provided the integrity of the epithelium of the cornea is preserved.
- Eye burns (thermal, chemical).
- Sympathetic ophthalmia.
- Postoperative period.
- Period after injury.
Contraindications in the application of Hydrocortisone:
- Diseases of the eyes of viral, purulent, fungal and tubercular origin.
- Primary glaucoma.
- Trachoma.
- Breach of the integrity of the shells of the eyes.
- Hypersensitivity to the components of the drug.
- Period of vaccination.
In pregnancy
During pregnancy, it may sometimes be necessary to treat with Hydrocortisone. Only a doctor can prescribe this medicine. Before use, you should read the instructions.
Hydrocortisone is a remedy that is safe for the body. But you need to pay attention to a number of its features. Hydrocortisone is a glucocorticosteroid, in which the substance hydrocortisone is used.This hormone is produced by the adrenal cortex and affects carbohydrate and protein metabolism.Therefore, Hydrocortisone can only be used when the benefit to the mother exceeds the risk to the fetus. During pregnancy, you can use the minimum dose of ointment and conduct a short-term course of treatment.
Studies have shown that Hydrocortisone can cause abnormalities in fetal development. Especially cautiously it should be used in the first trimester of pregnancy.
If the ointment is used during lactation, then breastfeeding should be temporarily interrupted.
To small children
Hydrocortisone is not contraindicated for use in children after one year.But you need to remember about precautions, since the use of hormonal ointments always carries the risk of developing side effects or complications.
If eye ointment Hydrocortisone is used externally and topically under the supervision of an ophthalmologist, there is no danger to the child. But it should be remembered that until the age of twelve years the drug is prescribed only under strict medical supervision.
If there is no improvement seven days after the beginning of treatment or the child's condition worsens, then it is necessary to stop using the ointment and consult a doctor.
Possible complications caused by the drug
Rarely Hydrocortisone can cause allergic reactions, burning, injected sclera, short-term blurred vision.
If you use the ointment for more than ten days, the intraocular pressure may increase with the possible development of steroid glaucoma with optic nerve damage and partial violation of the visual fields.
In some cases, subcapsular cataracts may occur, the wound healing process may be slowed down (in diseases that cause a strong thinning of the cornea or its perforation).
It happens that because of prolonged use of Hydrocortisone, a secondary bacterial or fungal infection is attached. In acute purulent eye diseases, glucocorticosteroids can enhance or mask existing infectious processes.
An overdose of ointment is rare. But if it occurs, there is a decrease in the effectiveness of insulin, hypotensive, oral hypoglycemic drugs, anticoagulants.It is possible to reduce the concentration of praziquantel and salicylates in the blood.
It should be remembered that with the simultaneous use of hydrocortisone and cardiac glycosides, digitalis intoxication, and when using ointments with preparations of silver and mercury, a mutual inactivation.
.Treatment of spasm of accommodation is described here.
Are colored eye lenses harmful? http://eyesdocs.ru/linzy/karnavalnye/vredny-li-cvetnye.html
.Video
conclusions
Ointment for the eyes Hydrocortisone is used to treat allergic, inflammatory diseases, as well as burns after complete healing of the cornea. The active substance of the drug is a glucocorticosteroid, which has anti-inflammatory, antipruritic, anti-allergic and anti-edema effects.
Before applying Hydrocortisone, we recommend that you read the instructions to avoid complications and side effects.
Also read about the consequences of wearing contact lenses and the specificity of the three-month lenses.