- 1.1Form of issue
- 1.2pharmachologic effect
- 1.3Pharmacodynamics and pharmacokinetics
- 1.4Indications for use
- 1.5The use of Febrofide is indicated when:
- 1.7Side effects
- 1.8Fibrofide, instructions for use
- 1.11Terms of sale
- 1.12Storage conditions
- 1.13Shelf life
- 1.14special instructions
- 1.17In pregnancy and lactation
- 1.19Price, where to buy
- 1.21IFK Pharmacy
2Fibrofid gel: instructions for use, composition, price and analogy
- 2.1Pharmacological action of the gel
- 2.3Medicinal composition
- 2.4Instructions for use
- 2.5Indications for use
- 2.6Contraindicated! To whom?
- 2.7Mode of application
- 2.8Side effects of the drug
- 2.11Drug analogues
- 3Fibrofide: instructions for use, recommendations
4Instructions for the use of the drug Fibrofid-gel
- 4.1Instructions for the use of gel
- 4.2Indications for use of the product
- 4.3Method of application, application
- 4.4Side effect
- 4.5Special instructions of the manufacturer
- 4.6Drug Interactions
5"Fibrofid" (gel): instructions for use, description, analogues, reviews
- 5.1Description, composition and packaging
- 5.2Pharmacodynamics of the external agent
- 5.3Pharmacokinetics of the drug
- 5.5Instructions for the use of the drug "Febrofid"
- 5.6Adverse Events
- 5.7Drug Interactions
- 5.8Special recommendations for the use of external means
- 5.9Price and analogy
- 5.10Patient feedback
6"Febrofid" (gel): instructions for use, composition, description and analogues:
- 6.1In what form can I purchase a medicine?
- 6.2What is included in the composition of the drug?
- 6.3What is the use of "Fibrofide"?
- 6.4What is the route of the drug in the human body?
- 6.5How does the drug work?
- 6.6When is the medication prescribed?
- 6.7Are there any contraindications to the use?
- 6.8Possible side effects
- 6.9How to use the drug correctly?
- 6.10Reviews of patients and doctors about the drug
- 6.11Terms of sale and storage of medicinal product
- 6.12Are there any similar drugs?
100 grams of the gel include 250 mglysine salt of ketoprofen(160 mgketoprofen) Is the active ingredient.
Additional components: polyethylene glycol, triethanolamine, propylhydroxybenzoate, methylhydroxybenzoate,carbomer, purified water.
Form of issue
The company "Medana Pharma" produces Febrofid in the form of an external gel, in aluminum tubes of 30 or 50 grams (in the form of an ointment, Febrofide is not produced).
Pharmacodynamics and pharmacokinetics
Gel Febrofid is an external (local) remedy from the groupNSAIDsand has a pronouncedanti-inflammatory, analgesicandantiexudativeeffectiveness.
The scope of the drug covers disease statesmusculoskeletal system (injuriestendons, joints, muscles, ligaments), as well asVenous defeat, lymph nodes,lymphatic vesselsandskin. In the case of a gel for treatmentarticular syndrome, the effects of the drug significantly reducejoint pain(both in the resting state of the joint and in its motion) are removedswellingjoints andmorning stiffness.
The active ingredient of the external agent -ketoprofen- characterized by good penetrating ability through the skin, thereby guaranteeing its delivery to problematic tissues and providing the maximum localanti-inflammatoryandanalgesicimpact.
Bioavailability of the drug is at the level of 5%. Binding to plasma proteins is almost complete - 99%. Cumulation in the body is not observed.
Metabolic transformationsketoprofenpass in the liver, after which about 80% of the drug in the formmetabolitesand 10% in unchanged form is excreted by the kidneys.
Indications for use
The use of Febrofide is indicated when:
- disease statesmusculoskeletal systeminflammatory-degenerative nature (includingtendinitis, arthritis, synovitis, bursitis, lumbago);
- symptomatic therapymyalgia, pain in the spine,neuralgiaand so on;
- uncomplicateddamage/injuries(including sportsbruises, stretching/gapstendons and ligaments,dislocations, post traumaticpain syndrome);
- inflammatory vascular pathologies (periphlebitis, phlebitis), lesions of lymph nodes and lymphatic vessels (superficiallymphadenitis, lymphangiitis) - in the combined treatment.
The use of Febrofide is prohibited when:
- wet dermatoses;
- pregnancy (in the third trimester);
- infected wounds, abrasions, burns;
- personalhypersensitivitytoketoprofen, other components of the gel or other drugs belonging to the groupNSAIDs.
Occasionally, during the use of Febrofide, negative effectsallergicnature (including dermalhyperemia, photosensitivity, purple, dermalexanthema).
Fibrofide, instructions for use
Gel Febrofid is designed exclusively for local (outdoor) use.
To achieve maximum effectiveness of treatment, a small amount of gel (3-5 cm) should be applied to the area of the problem area of the skin over the damaged area of the body and gently rub it with light movements palms.
There is no need to apply a dry bandage after the gel application procedure, since the drug is well absorbed, does not include dyes, has no smell and does not leave greasy or sticky stains on clothing.
Due to the external use of Febrofide, which does not allow high systemic absorption of gel ingredients, the likelihood of its overdose tends to zero (unlikely).
For prolonged and frequent useketoprofen, even externally may develop manifestations of interaction with other drugs.
Ketoprofenincreases the plasma contentNifedipineandVerapamil.
Combined application withCefamandol, oralanticoagulants, Cefoperazone, Heparin, antiaggregantsandthrombolyticsincreases the possibility ofbleeding.
Parallel use together withglucocorticoids, otherNSAIDs, Corticotropin, ethanolincreases the risk of formationulcerationsandbleeding of the gastrointestinal tract.
Joint use with drugsinsulinandoral hypoglycemicLS increases their hypoglycemic effectiveness and may require adjustment of dosages.
With combined treatment withValproatesodium is possible violationplatelet aggregation.
Ketoprofenreduces efficiencydiureticsandantihypertensive drugs, due to inhibition of synthesisprostaglandins.
Terms of sale
Fibrofid enters the pharmacy as an over-the-counter drug.
The temperature range of gel storage is 15-25 ° C.
From the moment of production - 2 years.
When using the gel, all precautions should be taken to prevent it from getting into the eyes.
It must be remembered that with the previous personalhypersensitivityto anyNSAIDsand applicationketoprofenin the present, the patient is at risk ofbronchoconstriction.
It is forbidden to apply Febrofid to the areas of skin that are prone tosuppurationormechanical damage.
If you need to use the gel for a long time interval, you need to monitor patients with severepathologies of the liver / kidneys.
When detectedskin rashesdiscontinue treatment and consult a doctor.
Below are the most popular analogues of Fefrofid, represented by various external dosage forms (ointments, sprays, creams, gels):
Features of the use of the drug in childhood in the instructions for Febrofid is not described, however, judging by the information about the effects of it of the active ingredient on this age group, obtained from the descriptions of its "Synonyms it is better to refrain from using the gel up to 15 years old.
In pregnancy and lactation
It is absolutely forbidden to use Febrofide inthird trimester of pregnancyand all alongbreast-feeding. In the first and second trimester of pregnancy, its use is allowed only in exceptional cases and in minimal doses.
In general, reviews about Fefrofid position this gel as a rather effective tool for removingpainful sensations, puffinessandinflammationsin traumatized areasmusculoskeletal system. In turn, a positive evaluation in patients receive such qualities of the drug as rapid absorption and the onset of the effect, as well as the absence of unpleasant odor and stains on clothing.
Negative reviews of Febrophide, also present in various forums, are most often left by people who used it to treat rather serious injuries, where the effects of one gel simply did not suffice to achieve the desired result.
Price, where to buy
The average price of Febrofid is 250 rubles for 30 grams and 350 rubles for 50 grams.
- Online pharmacies in RussiaRussia
- Online pharmacies in KazakhstanKazakhstan
- Fibrofid,% gel 50gMeda Manufacturing GmbH
- Fibrofid,% gel 30gMedana Pharma A.O.
Phlebofeed Medana Pharma Terpol, Poland
- Fibrofid,% 30 g gel externally. Medan Pharma A.O. (Poland)
- Fibrofid,% 50 g gel externally. Medan Pharma A.O. (Poland)
NOTE! Information about medicines on the site is a reference-generalizing, collected from public sources and can not serve as a basis for making a decision about the use of medications in the course of treatment. Before using the drug, be sure to consult with your doctor.
A source: http://medside.ru/febrofid
Fibrofid gel: instructions for use, composition, price and analogy
Treatment of pathology of the musculoskeletal system, as well as preventive measures, presuppose the use of various ointments and gels.
For fresh damages, it is better to use gels, cooling action, their action is aimed at eliminating pain syndrome, puffiness, inflammation, improvement of blood circulation and stimulation of recovery of soft tissues. It is very popular in the treatment of injuries Febrofid gel.
Pharmacological action of the gel
The gel has a complex action:
- removes inflammation;
- removes pain;
- reduces puffiness.
With discomfort in the joints, Febrofide is used to reduce pain, as in the process of movement, and in a state of rest, the elimination of stiffness of movements, especially in the morning hours, and swelling of the joints.
Fibrofid - gel for external use. The color of the preparation can be light yellow or transparent, colorless, slightly flickering. Available in tubes of aluminum with a volume of 30 and 50 grams, tubes are packed in cardboard packs.
The active, active substance of the gel is ketoprofen lysine salt, its amount in 100 grams of the drug is, grams. As additional components are used:
- macrogol 200 - 5 grams;
- trolamine grams;
- Carbomer grams;
- methylarrahydroxybenzoate 5 grams;
- propylarahydroxybenzoate 5 grams;
- Purified water - up to 100 grams.
Instructions for use
Experts do not recommend the use of ointment for the treatment of fresh injuries, this is due to the fact that it is important to achieve wound cooling at the first stage of therapy, and ointments contribute to a rise in temperature skin.
Also, if the wound is fresh, you can not rub the drug, you must apply it to the affected area and wait until it is completely absorbed.
To gel absorbed into the skin, you should wipe the affected area with lotion once a day, removing the film from the previously applied drug.
Indications for use
Fibrofide is used topically as an anti-inflammatory and pain-relieving agent. The drug effectively helps with:
- discomfort in the spine;
- Myalgia - pain in muscles of different origin;
- Neuralgia - defeat of peripheral nerves;
- diseases of the musculoskeletal system, in which inflammatory processes develop, for example, arthritis, tendonitis, synovitis, lumbago and bursitis;
- light injuries, dislocations, sprains of ligaments and tendons;
- pain caused by trauma;
- complex therapy, prescribed for pathologies of veins, lymph nodes and lymphatic vessels.
Contraindicated! To whom?
- Damage to the skin in which the infection develops.
- Eczema, wetting dermatoses.
- Late gestation.
- The period of breastfeeding.
- Individual intolerance and allergic reactions to the components of the gel.
- Propensity to allergic reactions.
Mode of application
To apply on the skin use a strip of gel from three to five centimeters. The agent is rubbed with light movements. Apply a woolen shawl or other bandages does not make sense, as the Febrifide is perfectly absorbed.
The gel is applied to the skin two to four times a day.
- Do not allow the gel to get on the mucous membranes, if you can not contact with the gel failed, you need to wash the mucous membranes with soap and water.
- It is forbidden to apply gel to open wounds.
- In renal or hepatic insufficiency, the course of gel treatment must be coordinated with a specialist.
- When rashes or other allergic reactions occur, the course of therapy should be stopped and appropriate adjustments should be made.
- The gel can cause sensitivity to ultraviolet radiation, so doctors recommend maximum limit stay in places not protected from the sun during the period of therapy, exclude visit to the solarium.
- Artificial sunburn is allowed only two weeks after the end of treatment.
- In the early stages of pregnancy, the drug can be used only with the consent of the doctor, on the last terms (third trimester), the use of Febrofide is prohibited.
Side effects of the drug
From the digestive system:
- nausea and vomiting;
- lack of appetite;
- feeling of fullness of the stomach;
- development of a stomach ulcer;
- From the urinary system- failures in the functioning of the kidneys.
From the central nervous system:
- noise in ears;
- feeling sleepy.
- skin peeling;
In very rare cases, shortness of breath or bronchospasm is possible.
The manufacturer of the gel is one company - Medan Pharma, Poland, but the cost of the drug is slightly different in different pharmacies. The cost of a tube with a volume of 30 grams averages 250 rubles. The price of a tube with a volume of 50 grams varies within 380 rubles.
Strongly expressed signs of the interaction of the gel with other medications appear only in the case of prolonged and systemic use of Febrofide.
- Joint use of the gel with drugs of a similar effect is possible development of peptic ulcer and gastrointestinal bleeding.
- Treatment together with anticoagulants and thrombolytics can provoke bleeding.
- The active substance - ketoprofen, contained in the gel, reduces the effectiveness of antihypertensive drugs.
- It is necessary to correct the dose of insulin, since the gel is able to increase the hypoglycemic effect of insulin.
|Name||Manufacturer||Form of issue||Price|
|Arketal Rompharm||Rompharm Company, Romania||Injection||176 rubles.|
|Arthrosilen||Dompe, Italy||Gel||370 rubles.|
|Bystrumgel||Akrihin, Russia||Gel||300 rubles.|
|Ketonal||Lek, Slovenia||Pills||220 rubles.|
|Ketoprofen||Vertex, Russia||Gel||61 rubles.|
A therapeutic regimen adequate to the state of health can only be performed by a specialist.
If the doctor does not have the opportunity, use the gel after a careful and detailed study of the instructions.
A source: http://OsteoHondroza.net/medikamenty/mestnye-sredstva/febrofid-gel.html
Fibrofide: instructions for use, recommendations
Gel for external use 2.5%from colorless to light yellowish color, transparent or slightly opalescent.
Excipients: macrogol 200-5 g, methyl parahydroxybenzoate 0.15 g, propyl parahydroxybenzoate 0.05 g, carbomer 1.5 g, trolamine 2.5 g, purified water up to 100 g.
30 g - aluminum tubes (1) - cardboard packs.
50 g - aluminum tubes (1) - packs of cardboard.
NSAIDs for external use. Has anti-inflammatory, antiexudative and analgesic effect.
Applied with lesions of joints, tendons, ligaments, muscles, skin, veins, lymphatic vessels and lymph nodes. With articular syndrome leads to a weakening of pain in the joints at rest and during movement, reduces the morning stiffness and swelling of the joints.
Ketoprofen penetrates well through the skin, which provides a local analgesic and anti-inflammatory effect. Bioavailability of the gel is about 5%. Binding to blood plasma proteins - 99%. Do not cum in the body.
Metabolised in the liver. About 80% of the dose is excreted in the urine as metabolites, less than 10% is released unchanged.
As a drug for external use with symptomatic treatment:
- Pain in the spine;
- inflammatory-degenerative diseases of the musculoskeletal system (including arthritis, bursitis, synovitis, tendinitis, lumbago);
- uncomplicated injuries (including sports, dislocations, sprains or ruptures of ligaments and tendons, bruises, posttraumatic pains);
- as a part of combined therapy for inflammatory diseases of veins (phlebitis, periphlebitis), lymphatic vessels, lymph nodes (lymphangitis, superficial lymphadenitis).
The drug is intended for external use.
A small amount (a strip 3-5 cm long) of the gel 2-3 times / day, apply to the corresponding area of the skin and gently rub.
It is not necessary to use dry bandages, tk. the gel is well absorbed through the skin, has no odor, contains no coloring agents, leaves no greasy stains, does not stain clothes.
Maybe:allergic reactions, skin hyperemia, photosensitivity, skin exanthema, purpura.
- wet dermatoses, eczema;
- infected abrasions, wounds, burns;
- III trimester of pregnancy;
- the period of lactation (breastfeeding);
- hypersensitivity to ketoprofen and / or other components of the drug;
- hypersensitivity to other NSAIDs (ketoprofen can cause bronchospasm in persons sensitive to acetylsalicylic acid and other NSAIDs).
In the I and II trimesters of pregnancy, the drug can be used only if necessary. In the third trimester of pregnancy, the use of the drug is contraindicated.
It is not recommended to use the drug during breastfeeding.
Care should be taken with long-term use in patients with severe failure of the liver function. Care should be taken with prolonged use in patients with severe renal failure.
The drug should not be applied to damaged areas of the skin.
Care should be taken with prolonged use in patients with severe hepatic or renal insufficiency.
In case of the appearance of a rash, it is necessary to stop the use of the drug and conduct appropriate therapy.
Due to low systemic absorption, an overdose of the drug Febrofid is unlikely.
With frequent and prolonged use, symptoms of interaction with other drugs may appear (same as in systemic use).
When co-administered with other NSAIDs, GCS, ethanol, corticotropin, ulceration and the development of gastrointestinal bleeding may occur.
Simultaneous use with oral anticoagulants, heparin, thrombolytic agents, antiaggregants, cefoperazone, cefamandol increases the risk of bleeding.
Ketoprofen reduces the effect of antihypertensive drugs and diuretics (inhibition of prostaglandin synthesis).
Increases the hypoglycemic effect of insulin and oral hypoglycemic drugs (dose adjustment is necessary). Co-administration with sodium valproate causes disruption of platelet aggregation. Increases the concentration of verapamil and nifedipine in blood plasma.
List B. The drug should be stored in a place protected from light and inaccessible to children at a temperature of 15 ° to 25 ° C. Shelf life - 2 years.
The drug is approved for use as a means of OTC.
A source: https://health.yandex.ru/pills/febrofid-6934
Instructions for the use of the drug Fibrofid-gel
For easier perception of the instruction, it is written in a simplified language on the basis of the original instruction - we tried not to use special terms. Before use, read the summary attached to the medical device.
Instructions for the use of gel
These instructions for the preparation of Febrofid, as well as reviews of doctors or patients are not a recommendation for self-administration. The appointment and determination of the dosage and the regimen are determined by the doctor.
Fibrofide - a tool for external use, refers to the group of NSAIDs (nonsteroidal anti-inflammatory drugs) with analgesic effect, has an antiexudative effect. Produced in the form of a gel in tubes of 30 and 50 grams.
The active substance is ketoprofen, which contains a number of analogues of Febrofide. Analogues: Oruvel, Fort-gel, F-gel, Flexen, Fefrofid, Ketoprofen Vramed, Ketoprofen-Verte, Ketoprofen, Valusal, Artrum, Arthrosilen, Ketonal, Fastum.
Ketoprofen is rapidly absorbed into the skin and effectively acts on local inflammatory processes and relieves pain in the lesions of lymphatic vessels, lymph nodes, veins, skin, muscles, ligaments, tendons, joints. The drug helps to reduce the morning stiffness in arthritis and arthrosis, relieves swelling.
Indications for use of the product
Ointment Febrifide is used symptomatically for pain in the back, spine, neuralgia and myalgia. The drug is effective in inflammatory-degenerative diseases of the organs of motion: lumbago, synovitis, arthritis, tendonitis, bursitis.
For therapeutic purposes, the gel is used for light injuries, including sports: stretching, dislocations, ruptures of tendons and ligaments, bruises.
For combined therapy for venous diseases - superficial lymphadenitis, periflebit, lymphangitis, phlebitis.
Method of application, application
The drug is used externally 2-3 times a day in a small amount (a strip of 3-5 cm).
Apply to the affected area and massaging movements rubbed until completely absorbed. Above, the bandage is not necessary to impose due to the good absorption of the ointment.
The drug has no color, smell, does not leave greasy marks, will not spoil clothes.
- Digestive system - vomiting, nausea, bloating, abdominal pain, decreased appetite, anorexia, constipation, diarrhea, abnormalities in liver function, erosion and stomach ulcers, perforation and bleeding in the digestive tract.
- The urinary system is a disorder in the functioning of the kidneys.
- The central nervous system is tinnitus, drowsiness, dizziness, headache.
- Allergic manifestations - itching at the site of application, redness, peeling, rash. Very rarely - local edema of the skin, bronchospasm or shortness of breath.
- individual intolerance to ketoprofen, other non-steroidal and anti-inflammatory drugs, acetylsalicylic acid;
- open lesions on the skin - acne, eczema, open wounds - abrasions, cuts, wet eczema;
- children under 15;
- the last period of pregnancy.
Special instructions of the manufacturer
It is necessary to avoid getting the ointment in the eyes, after applying the hand should be washed thoroughly with soap.
With long-term use of ointment, patients with renal and hepatic insufficiency need to monitor the condition of internal organs.
In case of adverse reactions, it is recommended that the drug be discontinued.
In rare cases, the use of the product gives rise to sensitivity to ultraviolet radiation. Therefore, during treatment, do not expose the skin to sunlight and do not visit the solarium for 14 days after the end of the use of the drug.
Simultaneous reception of Febrofide with other NSAIDs, corticotropin, ethanol, GCS, cefamandole, cefoperazone, antiplatelet agents, thrombolytics, heparin, oral anticoagulants, can provoke the formation of gastric bleeding, ulcers.
Ketoprofen reduces the effect of taking nipotenzive drugs or diuretics. For patients with diabetes mellitus, dose recalculation is necessary, since Febrofide increases the effect of insulin.
A source: https://vashaspina.ru/instrukciya-po-primeneniyu-preparata-febrosid-gel/
"Fibrofid" (gel): instructions for use, description, analogues, reviews
How to use and how much is the medicine "Febrofid" (gel)? Instructions for use, the price of the drug will be presented below.
From this article you will learn about what components are included in the composition of the drug, what indications it is assigned, how it affects the person and whether it has analogues.
Description, composition and packaging
What is an external remedy such as "Febrofid" (gel)? Instructions for use, patients' reviews report that this is% colorless, slightly opalescent or transparent drug (can have a light yellow hue), which include lysine salt ketoprofen.
Also, the composition of the drug in question includes additional components in the form of polyethylene glycol, propylhydroxybenzoate, triethanolamine, methylhydroxybenzoate, carbomer and purified water.
Pharmacodynamics of the external agent
What are the pharmacological characteristics of the drug "Fibrofid"? The gel, the instruction for which is enclosed in a cardboard package, is a local remedy belonging to the NSAID group.
This drug has a pronounced anti-inflammatory, antiexudative and analgesic effect. The area of application of this medicine is painful areas of the musculoskeletal system (injuries of joints, tendons, muscle tissues and ligaments).
Also, the drug in question is actively used for lesions of veins, lymphatic vessels, lymph nodes and skin.
After applying the gel, joint pain is significantly reduced, swelling and morning stiffness are eliminated.
Pharmacokinetics of the drug
What kinetic characteristics does the drug "Febrofid" (gel) have? The instruction for use states that ketoprofen (the active ingredient of the drug) has good penetrating power. After applying the gel to the skin, the active ingredient is quickly delivered to the problematic tissues, resulting in a local analgesic and anti-inflammatory effect.
The bioavailability of this drug is at 5%. The connection with plasma proteins is 99%. In this case, cumulation in the body is not noted.
Metabolism of ketoprofen is carried out in the liver.
Approximately 10% of the drug is unchanged and 80% in the form of metabolites excreted by the kidneys.
When should you use the drug "Fibrofid" (ointment)? Instructions for use indicate the following list of pathological conditions:
- uncomplicated injuries or injuries (including sports bruises, ligament and tendon ruptures, sprains, posttraumatic pain syndromes, dislocations);
- painful conditions of the musculoskeletal system, which are inflammatory-degenerative in nature (including arthritis, tendinitis, bursitis, synovitis, lumbago);
- cardiovascular pathologies of inflammatory nature (phlebitis, periphlebitis), lesions of lymphatic vessels and lymph nodes (for example, superficial lymphangitis, lymphadenitis) - in complex therapy.
Also it should be said that this medication is often used for symptomatic treatment of myalgia, neuralgia, pain in the spine, etc.
When you can not use the drug "Febrofid" (gel)? Instruction for use informs us that this drug is prohibited from prescribing at:
- wetting dermatoses;
- infected abrasions, wounds and burns;
- pregnancy (especially in the third trimester);
- hypersensitivity to the main ingredient and other components of the gel, as well as drugs that belong to the NSAID group.
Instructions for the use of the drug "Febrofid"
Gel "Fibrofid" is designed only for outdoor use.
To achieve the maximum effect from the treatment, a small amount of the drug (a strip of 3-5 cm) should be applied to the skin area that is located above the damaged site. After that, the medication should be rubbed with light massaging movements.
The application of a dry bandage after the procedure is not required. This is due to the fact that the drug in question is well absorbed, does not include dyes, has no smell and does not leave sticky and greasy stains on clothing.
Sometimes, against the background of the use of the drug "Fibrofid" in patients there are negative manifestations of an allergic nature. These include reactions such as skin hyperemia, photosensitivity, purpura and skin exanthema.
With frequent and prolonged use of the drug "Febrofid various manifestations of interaction with other medicines can be formed.
This means increases the content of "Verapamil" and "Nifedipine" in the blood.
When the combination of "Febrofid" with oral anticoagulants, "Cefamandol antiaggregants, "Cefoperazone thrombolytic and heparin, the risk of bleeding increases.
Simultaneous use of the gel with glucocorticoids, corticotropin, other NSAIDs and ethanol increases the risk of ulceration and bleeding in the gastrointestinal tract.
Joint use of the drug with insulin and oral hypoglycemic agents increases their hypoglycemic effectiveness.
Ketoprofen worsens the effect of antihypertensive and diuretic drugs because of the inhibition of prostaglandin synthesis.
When combined with sodium valproate, platelet aggregation may be compromised.
Special recommendations for the use of external means
What do I need to know before using the drug "Fibrofid" (gel)? Instruction for use informs that this medication can not be applied to areas of skin that are prone to festering or mechanical damage. Also, all precautions should be taken to prevent the gel from getting into the eyes.
If you need to use ointment in a patient with severe kidney or liver pathologies, especially for a long time, you need to constantly monitor his health.
If a rash is found on the skin, discontinue therapy and consult a doctor.
Price and analogy
The cost of the drug "Febrofid" is about 250 rubles for 30 g. You can replace this medication with tools such as Nimulide, Diclofenac, Ketoprofen, Butadion, Bystrumgel, Indomethacin, Arthrosilen, Orthofen, Finalagel, and others.
Now you have an idea of how to use the drug "Fibrofid" (gel). Instructions for use, price, reviews about this tool are described in this article.
Most patients respond to the medication in question solely with the positivity of the party. They argue that this drug quickly and effectively removes pain, and also eliminates swelling and inflammation in injured areas.
Also, patients note that after applying the gel, it is quickly absorbed, not stained clothes and leaving sticky spots on it.
As for negative responses, they are extremely rare. As a rule, the latter indicate the occurrence of allergic reactions in patients.
A source: http://.ru/article/217446/febrofid-gel-instruktsiya-po-primeneniyu-opisanie-analogi-otzyivyi
"Febrofid" (gel): instructions for use, composition, description and analogues:
Pain, discomfort, lack of mobility in muscles and joints require the use of drugs that help to adjust the usual pace of life.
One of such means is "Febrofid" (gel).
Instructions for use of this medication will tell you when a doctor can appoint him and how to use it in treatment.
In what form can I purchase a medicine?
Medicines that help with pain in the joints, muscles, developed for various reasons, very often have an appointment for local anesthesia and removal of inflammation. It is to such preparations for external use is the gel "Febrofid." Instructions for use, price, reviews about this medicine will be discussed below in the article.
What is included in the composition of the drug?
A detailed description of the medicine for external use of the gel "Febrofid" instructions for use. The composition of this remedy is not very complicated, there is only one active ingredient in it - ketoprofen in the form of lysine salt.
This is a non-steroidal anti-inflammatory substance, included in the List of Essential and Essential Medicines, approved by the Government of Russia. The remaining substances play the role of forming auxiliary ingredients.
- carbomer - gelling agent, thickener, widely used in pharmaceuticals and cosmetics;
- methylhydroxybenzoate - a preservative with antimicrobial properties;
- polyethylene glycol - forming polymer;
- propylhydroxybenzoate - a water-based preservative;
- triethanolamine - a substance for giving gel consistency to the drug;
- purified water.
What is the use of "Fibrofide"?
One of the popular on the drugstore shelves and used to eliminate pain with local application of the drug - "Febrofid" (gel).
Instructions for use of this tool will tell you what is in the medicine, what are its pharmacokinetics and pharmacodynamics.
This drug, produced in the consistency of the gel, is used as a anti-inflammatory and analgesic for external use with some joints and muscular diseases.
What is the route of the drug in the human body?
The main active substance of the drug "Febrofid" is the lysine salt of ketoprofen. It is well absorbed through the skin, deeply penetrating to the site of the problem.
With blood proteins, this substance binds to 90%, which allows it to act inside tissues, and not just on the surface of the skin.
The huge plus of this medication is that it does not accumulate in the body, but, passing through the process of metabolism in the liver, is excreted in the urine.
How does the drug work?
Since the active component of the drug substance belongs to the non-steroidal anti-inflammatory components, it suppresses the functional of the cyclooxygenase 1 enzyme (COX1). It is this work of the drug that relieves the painful sensations caused by the inflammatory process.
Unfortunately, inhibition of COX1 does not give such a therapeutic effect as COX 2 suppression, and if the drug was taken orally or orally, it would threaten with a huge number of ulcerogenic (gastroduodenal) side effects, potentially dangerous for health. But in this case, the drug is used externally, which reduces its potential side effect and a minimum.
Before applying the "Febrofid" gel, the instructions for use should be studied by the patient himself. It details the effect of this medicine.
And in addition to the anesthetic effect, the lysine salt of ketoprofen has the ability to lower the temperature and have an anti-inflammatory effect.
In this complex therapeutic function a great advantage of this drug, belonging to the NSAID group.
When is the medication prescribed?
All the detailed information necessary tells about the non-steroidal anti-inflammatory drug "Febrofid" (gel) instructions for use. Reviews of patients and doctors about it are mostly positive.
After all, this medicine is an active component contains a substance that helps to remove inflammation and pain, as well as fever. "Febrofid" is available in the form of a gel, which is a good form for external topical application. The drug is prescribed by the attending physician after diagnosis.
Indications for the use of this drug are:
- lymphadenitis (superficial);
- post-traumatic pain syndrome;
- stretching of ligaments, muscles and tendons;
The drug "Fibrofid" is used most often in complex therapy as a symptomatic means for eliminating painful sensations, inflammatory process and temperature rise caused by it. Additional methods of treatment and medications are also prescribed by the doctor.
Are there any contraindications to the use?
For the preparation "Febrofid" (gel), the instruction for use indicates the following contraindications for use:
- dermatoses wetting;
- infected cuts, wounds, abrasions;
- eczema of various etiologies.
Since this drug belongs to the group of non-steroidal anti-inflammatory drugs, its administration is forbidden to pregnant women in the third trimester. The same applies to those who feed the baby with breast milk.
Do not use this medication for people who have an individual hypersensitivity to both ketoprofen and other non-steroidal anti-inflammatory substances.
Contraindication is also the child's age of the patient - up to 15 years.
This is due to the fact that no studies of the drug have been conducted, and the belonging of the drug to NSAIDs makes it potentially dangerous for children of early and younger age.
The drug with extreme caution is allowed to apply to pregnant women, who are in the first and second trimesters of pregnancy. This can be done only on the advice of the attending physician, informed of pregnancy, and under his regular supervision.
Possible side effects
Since the drug "Febrofid" (gel) belongs to the group of NSAIDs, this instruction also underscores the use of side effects.
These include allergic manifestations such as hyperemia (reddening of the skin), skin exanthema (rashes on the skin), purpura (small capillary hemorrhages under the skin), photosensitization (hypersensitivity of the skin and mucous to the ultraviolet portion spectrum).
Such undesirable effects of this drug are rare.
How to use the drug correctly?
The drug, belonging to the group of NSAIDs, called "Febrofid" is released in one dosage form in the form of a gel for external use.
Before applying the product, the skin should be cleaned with soap and warm water and wipe dry.
Then 3-5 cm of gel squeezed out of the tube on a painful place and rub it into the skin with soft, as if massaging movements, without pressing. It is not necessary to put any bandage over the product, as the product is quickly absorbed.
After the gel has been smeared on the problem area, you need to wash your hands thoroughly with soap, getting the gel in the eyes or on the mucous membranes, they must be washed thoroughly or rinsed clean water.
Reviews of patients and doctors about the drug
A detailed description of the preparation "Febrofid" instructions for use, price and reviews make this tool in demand in the segment of drugs of this kind.
Both doctors and patients describe the effect of the drug as effective, helping to calm soreness, swelling by reducing inflammation at the site of application of the product to the skin.
Occurrence of side effects is described extremely rarely, among the reports, several cases of hyperemia are indicated.
Separately, patients note that the gel is well absorbed into the skin, does not leave a sticky feeling, does not stain clothes and does not smell. For those who continue to work during treatment with this drug, the last item is especially relevant.
Terms of sale and storage of medicinal product
The necessary detailed information contains about the medicinal product "Febrofid" (gel) instruction for use.
The price of this drug varies among different vendors and varies depending on the volume of the tube from 250 to 400 rubles. The drug is dispensed from pharmacies without a doctor's prescription at the request of the buyer.
Keep it at room temperature. After the expiration date, and since the release date is 2 years, you can not use the drug.
Are there any similar drugs?
Describes the working substance of the drug "Febrofid" (gel) instructions for use.
Analogues of this drug, containing the same active component, and this ketoprofen lysine salt, are available in various pharmaceutical forms.
One of the most famous, widely advertised means is Ketonal, and also Fastum.
Also in pharmacies you can buy drugs that have a similar effect, but have in their composition other non-steroidal anti-inflammatory substances. Such means include "Voltaren "Nimulid "Diclofenac "Naize" and many others. Which of the means to apply in a particular case, the doctor advises.
He will tell you all the necessary information about the medicinal product used externally for the treatment of many diseases - gel "Febrofid" - instructions for use.
The drug belongs to the NSAID group, which requires the appointment of a doctor for its use after diagnosis. The drug, although it is released from the pharmacy network without a prescription, at the request of the buyer, yet it is not worth using it alone.
It is necessary to establish the cause of the pain, the severity of the disease or injury, and only then determine the necessary treatment.
A source: https://www.syl.ru/article/344670/febrofid-gel-instruktsiya-po-primeneniyu-sostav-opisanie-i-analogi