Eye Drops Dexatobropt: Instructions for Use

Infectious diseases of the eye, like other infections, increasingly require the use of new potent drugs with additional properties. Therefore, combined medicines are in high demand among the population - they, in addition content in the traditional antibiotic, most often have anti-inflammatory or antihistamine effect. An example of such a drug may serve as eye drops Dexatobropt.

Description of the preparation

The drug is a combination of two active ingredients: antibiotic Tevomycin (3 mg in 1 ml) and glucocorticosteroid Dexamethasone (1 mg in 1 ml).The number of excipients includes sodium sulfate, sodium chloride, tyloxapol, purified water, etc.

The preparation is a suspension of white or almost white color, in which a precipitate is possible.It quickly disappears even with slight shaking. Every 5 ml of the suspension are in a plastic bottle with a built-in dropper covered with a cap. Vials are packed in cardboard packs one at a time and are equipped with instructions.

The storage conditions of the preparation contain the following requirements: protection against direct sunlight, t not higher than + 25 ° C, inaccessibility to young children. If the conditions are met, Dexatobropt retains medicinal properties for at least 3 years. After opening the bottle it is recommended to use drops for 1 month.

Pharmacological action and group

The drug belongs to the group of anti-inflammatory and antimicrobial medicines. Its pharmacological action consists of the therapeutic effects of its active ingredients:

• Tobramycin- antibacterial agent belonging to the group of aminoglycosides. It has bactericidal activity (destroys microbes) against staphylococci, Pseudomonas aeruginosa, Escherichia coli, Enterobacter, Salmonella, Proteus, Klebsiella, etc. Has no therapeutic effect when infected with Group D streptococci (most strains). According to the instructions for use, Tobramycin penetrates well into the tissues of the cornea and conjunctiva, but in the systemic circulation it is found in very low concentrations;
• Dexamethasone- a substance from the group of synthetic glucocorticosteroids, which have anti-allergic and anti-inflammatory properties. The product perfectly penetrates the epithelium of the cornea and conjunctiva, and the penetration rate increases with traumatic inflammations.

The greatest effect when using the drug is observed after 10-20 minutes. after instillation. Minimal doses of the drug enter the systemic circulation, are metabolized in the liver and kidneys and are excreted in the urine.

Indications and contraindications

Dexatobroplet is effective in most infectious inflammations caused by microorganisms that are sensitive to the preparation, as well as in mixed forms of diseases. Its purpose is justified in case of appearance of the following pathologies:

• Blepharitis- inflammation of the edges of the eyelids due to infection of the microbes of the eyelash follicles. The causative agents can be mites demodex, viruses, bacteria. Symptoms of the disease, in addition to rubbing and itching in the eyes, include the appearance of a sticky secretion at the edge of the eyelids;
• Conjunctivitis- inflammatory process in the conjunctiva, the mucous membrane of the eyeball. It can also have a different nature of infection, and the main symptom is the redness of the eye proteins, accompanied by itching and lacrimation with an admixture of pus;
• Blepharoconjunctivitis- Mixed pathology, when the conjunctiva and eyelids are involved in the inflammatory process. The flow of mixed infection is characterized by more pronounced signs of inflammation, edema of the eyelids, the formation of acne and tumors;
• Keratite- Inflammation of the cornea, accompanied by opacity, ulceration and pain. The color of opacity can be from dull white to yellowish. With incorrect treatment, such a stain can degenerate into a thorn. Dexatobroplet is used to treat keratitis in the deep layers of the cornea.

Blepharoconjunctivitis

The drug is successfully used to prevent and treat inflammatory processes during rehabilitation after trauma or surgery.

Contraindications

The official instruction indicates a number of conditions in which the use of the drug is inexpedient or dangerous. These include:

• Individual intolerance of the drug components, both basic and auxiliary;
• Mycobacterial and fungal eye infections;
• Identification of the viral nature of inflammation;
• Damage to the epithelium as a result of trauma or removal of a foreign body;
• Gestational period;
• Persons under the age of 18 years.

The period of breastfeeding is highlighted in a separate line indicating the possibility of using with extreme caution.

In pregnancy

The drug contains a corticosteroid and an antibiotic - substances that are extremely undesirable for admission during pregnancy.Some instructions indicate this period in the list of contraindications, but the ban is based on insufficient study of the drug.Therefore, an ophthalmologist, if absolutely necessary, can prescribe a medicine even when the child is pregnant.

However, one should know that it is undesirable to use it for more than 2 weeks, and if necessary, change the drug - replace the antibiotic and use an NSAID.When dropping drops, pinch the corner of the eye - in this case, systemic penetration will be minimized and the risk of negative effects on the fetus will be significantly reduced.

To small children

In the treatment of children under the age of 18, Dexatobropt does not apply, since the mechanism of its effect in this the age group has not been studied, and reliable data on the effect of the components of the drug on the growing children's organism are absent.

Possible complications caused by the drug

In the treatment of eye drops, it is possible to develop some negative phenomena that occur rarely:

• Burning and pain in the eyes;
• Redness and swelling of the conjunctiva;
• Headache (with an increase in IOP).

With long-term use (more than 3 months. ) of the drug, side effects can become more severe and extensive:

• Mycosis of the cornea;
• Deceleration of tissue regeneration;
• Development of secondary infection;
• Occurrence of posterior subcapsular cataract.

The use of dexatobropt for a long time requires constant monitoring of IOP in order to prevent serious complications.

When treating eye drops should pay attention to several points:

• Do not touch the tip of the dropper to the surface of the eye to avoid infection;
• Do not use the drug with other aminoglycosides, because you can provoke their overdose in the body;
• Before use, remove contact lenses and wear them only after 15 minutes. break;
• To maintain a time interval after instillation, if necessary, to perform activities requiring increased attention.

When developing allergic reactions or other side effects, stop taking the medication and consult a doctor for advice.

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conclusions

Eye Drops Dexatobroplet is an effective ophthalmic product with a combined action: antibacterial and anti-inflammatory. It is successfully used in a number of infectious inflammations of the eyes caused by microorganisms sensitive to the active components of the preparation.

The drug has a number of contraindications and side effects, so it can only be used after a thorough examination of the ophthalmologist and the appointment of appropriate treatment.