Drops for eyes Kosopt

This drug is available in the form of eye drops as a combined antiglaucoma medication, which is intended to reduce intraocular pressure by reducing the secretion of secretion of fluid in organ. The action of the drug, in most cases, is well tolerated by patients.

Kosokt in the form of drops for the eyes is a clear, colorless or almost colorless, slightly viscous liquid. Produced in plastic bottles of 5 ml.

Its effectiveness is due to the joint functioning of the two active substances. Drops are produced by a French company called "Merck Sharp & Dohme".

Pharmacological action of the drug

The main components of the drug - dorzolamide hydrochloride and timolol maleate - contribute to the rapid and effective reduction of intraocular pressure.Both these active substances reduce the secretion of the aqueous humor, and timolol maleate can slightly improve its outflow.

Drops promote lowering of intraocular pressure

Dorzolamide and timolol penetrate into the systemic blood stream with topical application. Dorzolamide hydrochloride accumulates in blood erythrocytes at an extremely low concentration in the plasma, the half-life period is 4 months.With the administration of timolol maleate in the form of eye drops, the effect of reducing intraocular pressure occurs in 20 minutes, becomes maximum after 2 hours, and the drug acts for at least 24 hours.

Being complex in composition, the Kosopt drops have two active substances. One of them, dorzolamide hydrochloride, is present in an amount of 2, 6 mg per ml, equivalent to 20 mg of the base of dorzolamide. The second active ingredient is timolol maleate in an amount of 3 mg per 1 ml, which is equivalent to 5 mg of timolol base.To create a stable solution, additional substances are used to ensure storage of the drug during the claimed shelf life. These include substances such as: 50% benzalkonium chloride solution, sodium citrate, mannitol, hydroxyethylcellulose, sodium hydroxide solution, distilled water for injection.

Cosmetic eye drops are ideally suited for reducing intraocular pressure, have a long-term effect.

Indications and contraindications in use

In order to ensure that the course of treatment was most effective, it is necessary to read the indications and contraindications in the application.

Indications for use

These eye drops are ideal for:

• Treatment of open-angle glaucoma.
• Pseudoexfoliation of glaucoma.
• Increased intraocular pressure.

Contraindications for use

Kosopt is not recommended for:

• Bronchial asthma, including in the past, since cases of such patients were registered in the case of bronchospasm.
• A serious stage of chronic obstructive pulmonary disease.
• Heart Failure, with the first symptoms of which the medication should be discontinued.
• AV blockade of the second and third degree.
• Sinus bradycardia.
• A shock of cardiogenic nature.
• The process of dystrophy in the corneal region.
• problems with the work of the kidneys, when the clearance of creatinine is less than 30 milliliters per minute.
• At the age of up to eighteen years, since the safety of the drug for this group of patients is not yet fully understood.
• Pregnancy.
• Allergies or strong body reaction to the components of the drug.

Use the drug should be only after acquainting with the contraindications, so you can avoid complications.

Possible complications caused by the drug

In the vast majority of cases, the drug is transferred very well. Systemic side effects are most often expressed poorly and do not require the cancellation of treatment. In extreme cases, local reactions from the eyes, hypersensitivity or allergy develop.The most common side effects are burning and itching in the eye area, taste change, blurred vision, lacrimation, corneal erosion or conjunctiva injection.

Almost no shortness of breath, a decrease in heart rate, nausea, respiratory failure, dermatitis, atrioventricular block or detachment of the choroidal membrane of the eye.Possible corneal edema in patients who underwent intraocular surgery or with chronic corneal defects.

Complications that can cause dorsolamide hydrochloride: headaches, eyelid inflammations, fatigue, iridocyclitis, rashes, paresthesia, temporary myopia, as well as systemic reactions - pharyngeal edema, bronchospasm, nosebleeds, dry mouth, rash and itching.

Possible complications that may cause timolol maleate in topical application: conjunctivitis, blepharitis, keratitis, dryness, decrease sensitivity of the cornea, visual impairment, as well as ringing in the ears, heart rhythm disturbances, edema, lower limb temperature, bronchospasm, lowering blood pressure, coughing, headaches, fatigue, chest pains, allergic reactions, rashes of various kinds, insomnia, disorders digestion, depression, etc.With systemic application, there is rarely pain in the legs and hands, heart problems, vomiting, urination disorders, hyperglycemia or hypoglycemia, increased sweating, scabies, weakness, various types of dermatitis, drowsiness, disorders attention.

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conclusions

Kosopt - this is an excellent drug that can have a powerful pharmacological effect. But also has a number of contraindications, which should be read in person or in consultation with a specialist.

Also, read about other drops that reduce intraocular pressure, and what tools can be used for glaucoma.