Diclofenac tablets: instructions for use

Tablets Diclofenac is a non-steroidal anti-inflammatory drug.

Has anti-inflammatory, analgesic, antiplatelet and antipyretic effect. The most effective for inflammatory pain. Used for symptomatic treatment of diseases of the musculoskeletal system, reduction of various types of pain syndrome.

On this page you will find all information about Diclofenac: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used tablets Diclofenac. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

NSAIDs.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much are Diclofenac tablets? The average price in pharmacies is at the level of20 rubles.

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Form of issue and composition

Tablet forms: tablets in the k / r sheath 25 mg, in the p / o sheath 25 and 50 mg, retard 100 mg.

• Ingredients of the tablets in the enteric coating: 25 or 50 mg Diclofenac sodium, disubstituted calcium phosphate, starch, magnesium stearate, polyvinylpyrolidone K30, talc purified, cellulose acetate, indoresin, diethyl phthalate, carmosein lacquer, titanium dioxide, ponso 4R varnish, iron oxide red and yellow.
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Pharmacological effect

It suppresses the exudative and proliferative phases of inflammation. Reduces the amount of serotonin, histamine and bradykinin, increases the threshold of perception of pain receptors; reduces the concentration of PG in the center of thermoregulation, increases heat transfer, reduces body temperature; suppresses aggregation thrombocytes.

Indications for use

The tablet form of Diclofenac is prescribed to alleviate pain in attacks of psoriatic, gouty, juvenile arthritis, ligament injuries and articular apparatus of the knee joint.

Tablets can be used for pain in the spine. Arising from osteochondrosis and degenerative changes in the intervertebral discs. It is used for infringement of sciatic and lumbar nerves, tunnel syndrome of the wrist or elbow joint. It is irreplaceable in case of trauma, stretching or dislocation, including athletes and persons working in physically heavy industries.

Contraindications

Contraindications to the use of tablets:

• inflammatory bowel disease;
• exacerbation of gastrointestinal lesions (erosive-ulcerative);
• bleeding from the digestive tract;
• severe failure of kidney or liver function;
• condition after coronary artery bypass grafting;
• pregnancy and lactation;
• "Aspirin triad" - intolerance of NSAID drugs in patients with bronchial asthma and polyps in the nose;
• children under 6 years old for tablets 25 mg, other dosages - contraindicated up to 18 years;
• lactose intolerance, lactase deficiency, glucose-galactose absorption pathology.

Cautiously appointed at the following conditions: inflammatory bowel disease, alcoholism, erosive-ulcerative diseases of the gastrointestinal tract chronic exacerbations), diabetes, diverticulitis, induced porphyria, bronchial asthma, anemia, congestive heart failure, edematous syndrome, arterial hypertension, hepatic or renal insufficiency, a condition after serious surgical interventions, advanced age, systemic pathologies connective tissue.

Application in pregnancy and lactation

Contraindicated in the III trimester of pregnancy. In the I and II trimester of pregnancy should be used according to strict indications and in the lowest dosage.

Diclofenac penetrates into breast milk. If it is necessary to prescribe the drug during lactation, breastfeeding should be discontinued.

Instructions for use

The instructions for use indicate that diclofenac in the form of tablets should be taken orally, without chewing and washing down sufficient amount of water, preferably 30 minutes before meals (to achieve a rapid therapeutic effect). It is also possible to take the drug before, during or after a meal.

• Children from 15 years and adults Diclofenac appoint 2-3 times a day for 25-50 mg (maximum - 150 mg per day). After the improvement, the dose is gradually reduced and switched to maintenance therapy - 50 mg per day.

In the treatment of juvenile rheumatoid arthritis, the daily dose can be increased to 3 mg / kg of body weight.

For children, the drug is usually prescribed in the following doses (single / daily):

• 6-7 years (20-24 kg) - 25/25 mg;
• 8-11 years (25-37 kg) - 25 / 50-75 mg;
• 12-14 years (38-50 kg) - 25-50 / 75-100 mg.

How long can I apply?

Most pathologies and complications associated with the use of this drug, arise against the background of the duration of treatment. How to take Diclofenac in tablets to prevent the appearance of unpleasant symptoms? First of all, the process should be supervised by the doctor. Adult patients are prescribed 2-3 tablets per day. The dose decreases with the onset of improvement.

Duration of admission should not exceed 2 weeks, except in difficult cases.

Side effects

With oral administration, the following side effects are possible: dyspeptic phenomena, erosive and ulcerative lesions of the digestive canal, perforation of its walls, gastric and intestinal bleeding, increased drowsiness, dizziness, hypersensitivity reactions, irritability.

Overdose

Symptoms: hypotension, renal insufficiency, seizures, gastrointestinal irritation or respiratory depression may occur.

Treatment: there is no specific antidote. When acute poisoning is necessary as soon as possible to stop absorption of the drug from the digestive tract. It shows gastric lavage, the appointment of activated charcoal and other symptomatic and maintenance therapy. The use of forced diuresis, dialysis or blood transfusion is not justified, in view of the fact that NSAIDs bind to a large extent with serum proteins and have extensive metabolism.

special instructions

During the period of treatment with the drug, systematic monitoring of peripheral blood, liver function, kidney function, fecal blood test should be carried out.

Patients taking the drug should refrain from activities that require increased attention and rapid mental and motor reactions, alcohol consumption.

Drug Interactions

1. Reduces the effect of hypoglycemic agents.
2. Reduces the effects of hypotensive and hypnotics.
3. Acetylsalicylic acid reduces the concentration of diclofenac in the blood.
4. Increases the concentration in the plasma digoxin, methotrexate. preparations of lithium and cyclosporine.
5. Simultaneous use with paracetamol increases the risk of developing nephrotoxic effects of diclofenac.
6. Cefamandol, cefoperazone, cefotetan, valproic acid and plikamycin increase the incidence of hypoprothrombinemia.
7. Cyclosporine and gold preparations increase the effect of diclofenac on the synthesis of prostaglandins in the kidneys, which increases nephrotoxicity.
8. Simultaneous administration with ethanol, colchicine, corticotropin and preparations of St. John's wort increases the risk of bleeding in the gastrointestinal tract.
9. Reduces the effect of diuretics, against the background of potassium-sparing diuretics increases the risk of hyperkalemia; against the background of anticoagulants, thrombolytic agents (alteplase, streptokinase, urokinase) - the risk of bleeding (more often from the gastrointestinal tract).
10. Diclofenac enhances the effect of drugs that cause photosensitivity. Drugs that block tubular secretion increase the concentration in the plasma of diclofenac, thereby increasing its toxicity.
11. Increases the likelihood of side effects of other NSAIDs and glucocorticosteroids (bleeding in the gastrointestinal tract), toxicity of methotrexate and nephrotoxicity of cyclosporine.

Reviews

We picked up some of the people's feedback about Diclofenac tablets:

1. Irina. I have arthritis and gout. Once the doctor has appointed or nominated to drink tablets Diclofenac. Symptomics relieves very badly, the pain has not really gone, the swelling of the joints and stiffness has remained. Moreover, it also affects the stomach badly. After waking up in the morning after the reception, I noticed that my stomach was puffed up, I was a little sick, and there was a slight nausea. After reading the instructions, I realized that the side effects of the drug are much greater than the therapeutic properties. In the future I did not take this medicine. The doctor found a suitable alternative.
2. Tatyana. Diclofenac is a widely used analgesic and anti-inflammatory drug. My husband and I were often prescribed this drug, in different dosage forms, when the pains in the back and joints were disturbed. The medicine quickly relieves pain, but when long-term treatment is prescribed, the gastrointestinal tract is very afflicted. Therefore, we refrain from taking it as far as possible and choose more sparing drugs.
3. Anatoly. With serious chronic diseases, these pills can not be cured, they will only remove the symptoms. I have a chronic disease. I take on average once a year, most often by this time there is pain in the joints, stiffness in the morning and swelling. In general, a good drug, it is inexpensive.

Analogues

If for some reason you need to replace the pill, then you can choose one of the following analogs of the drug:

• Ibuprofen;
• Sulindak;
• Orthophene;
• Naproxen;
• Diklak;
• Tenoxicam;
• Clofezon;
• Piroxicam;
• Neurodiclavitis;
• Indomethacin.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The preparation should be stored in a dry place, protected from light, inaccessible to children, at a temperature not exceeding 25 ° С.

Shelf life - 3 years. Do not use after the expiry date printed on the package

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