What helps Miramistin: instructions for use

Miramistin is an antiseptic drug for local and external use.

It is endowed with a wide spectrum of antibacterial action, including hospital-acquired microbial strains resistant to antibiotics. The drug has a pronounced bactericidal (disastrous for bacteria) effect on gram-positive (Staphylococcus spp., Streptococcus spp.) and Gram-negative (Escherichia coli, Klebsiella spp., Pseudomonas aeruginosa) bacteria.

The development of this effective tool was carried out back in the 70s of the last century by Professor Krivoshein and a group of researchers from Russia and Ukraine. Due to various political events in the USSR, scientific work often stopped because of a lack of funding. Therefore, the drug was registered as a drug only in 1991.

Clinical and pharmacological group

MIRAMISTIN is an antiseptic drug of complex action.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Miramistin cost in pharmacies? The average price in 2018 is at the level of200 rublesfor solution and370 rublesfor the spray.

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Form of issue and composition

The medicine is available in the form of a solution that is applied topically. It is a clear liquid without color, which foams if it is shaken. Miramistin solution is contained in polyethylene bottles of 50 ml, 100 ml, 150 ml or 200 ml, which are embedded in cardboard boxes. The kit also includes a spray nozzle or a spray pump. The form of release for use in a hospital is 500 ml bottles.

Active ingredient: benzyldimethyl-myristoylamino-propylammonium chloride monohydrate, 100 mg
Excipients: purified water, up to 1 liter

Candles and Miramistin tablets are not available.

Pharmacological effect

With topical use, Miramistin is not absorbed into the mucous membranes and skin. It is active against hospital strains, even resistant to antibiotics. The active substance interacts with the lipid layer of membranes of microorganisms. This causes their destruction and increases permeability.

Under the influence of Miramistin, aerobic and anaerobic bacteria, gram-positive and gram-negative organisms die. Simultaneously, there is an increase in the activity of immune cells. This leads to stimulation of nonspecific immunity, acceleration of the healing process. Stimulation of protective properties occurs due to activation of various functions of phagocytes.

Indications for use

What helps? Miramistin is used for a variety of diseases in different areas of medicine:

Otorhinolaryngology: treatment of otitis (acute and chronic form), tonsillitis, laryngitis, sinusitis, as well as pharyngitis.
Traumatology and surgery: treatment of purulent wound surfaces, prevention of suppuration, therapeutic therapy in the purulent-inflammatory process of the musculoskeletal system.
Gynecology and obstetrics: carrying out preventive and curative procedures aimed at eliminating suppuration in the injured crotch area, arresting the inflammatory process, treatment of infections after childbirth.
Combustiology: therapeutic therapy for severe burns (grade 2 and 3), preparatory treatment of the burn surface before dermaplasty.
Dentistry: preventive measures, medical procedures for inflammatory diseases of the oral cavity of infectious nature (stomatitis, periodontitis, gingivitis, periodontitis), hygienic care for dentures.
Dermatology, as well as venereology: the implementation of therapeutic and preventive procedures aimed at eliminating fungal lesions of the skin, as well as mucous membranes.
Urology: treatment for urethritis, cystitis or urethrostrostitis (acute or chronic form), if the disease is caused by specific and nonspecific pathogenic microorganisms.

The drug can be used for the individual prevention of diseases that are transmitted sexually (including genital candidiasis and herpes, chlamydia, syphilis, trichomoniasis, and gonorrhea).

Contraindications

Do not use Miramistin in the form of a solution with increased sensitivity. It is not used to treat children under 3 years old.

Ointment is also not used for hypersensitivity to the components. Children under one year and in general in pediatric practice ointment is not used.

Use in pregnancy and lactation

Miramistin at pregnancy, and also at thoracal feeding can be applied at presence of corresponding indications.

If a throat rinse is performed during pregnancy, or is buried in the nose during pregnancy Miramistin, the likelihood of absorption of the active substance into the bloodstream is unlikely. Therefore, for the throat, as well as for disinfection of the affected surfaces in the process of bearing the child, Miramistin can be used. How to use the medicine, you should ask the doctor in detail.

During pregnancy during treatment, this drug should be periodically observed by a specialist.

Dosage and route of administration

The instructions for use indicate that the particular application of Miramistin will depend on the scope of medicine and the specific disease.

Prevention of FBP

To prevent sexually transmitted diseases, miramistin will be effective if it is used no later than 2 hours after the sexual intercourse.

To do this, using the attached urological applicator, the contents of the vial are introduced into the urethra for 2-3 minutes: 2-3 ml (for men), 1-2 ml and an additional 5-10 ml in the vagina (for women). The skin is also exposed to the inner surfaces of the thighs, peribola region and external genitalia.

After this procedure, it is recommended to refrain from urinating for 2 hours.

Stomatology

In dental practice, antiseptic Miramistin in the form of a solution is applied in accordance with the following recommendations and instructions:

With gingivitis and periodontal treatment, the composition is expedient only after the enamel has been cleared of soft deposits and tartar.
After tooth extraction or dissection of the abscess, the "baths" with antiseptic are shown: it is necessary to take a tablespoon of solution into the mouth and hold for at least 1 minute.
In the treatment of herpetic stomatitis, the remedy is used to rinse together with immunomodulating and antiviral drugs, the procedure is performed 3 times a day for 1 minute.
In order to disinfect dentures, you must first clean them, then apply antiseptic.
In case of fungal diseases of the oral cavity, Miramistin is used both for mouth and throat rinsing and for topical application for mucosal treatment with a cotton swab.

ENT

With ENT diseases, the drug is used for rinsing and local treatment, as well as when washing the nose. Use antiseptic 3-4 times a day, 10-15 ml of funds for 1 procedure. Dosages and schedules may vary depending on the nature of the disease and the age of the patient.

Miramistine for the throat

Inhalations with miramistin in a nebulizer are shown to children with infectious diseases of the upper respiratory tract. Adults like this are rarely prescribed because of their low effectiveness. To carry out inhalation with Miramistin in a nebulizer, children need to take 10 drops of antiseptic and dissolve them in 30-40 drops of saline.

The resulting mixture to breathe through the mask for 5-7 minutes. Frequency - twice a day. Inhalations with Miramistin in a nebulizer are administered to children for 5 days. During the procedure, breathe should be strictly nose.

Miramistine Spray: instructions for use

Below, we describe how to optimally use Miramistin for irrigation of the mouth and throat, or for traditional rinsing of the mouth, both in children and adults. Miramistin Spray Instruction for Use contains the following indications ...

First you need to activate the nozzle-sprayer -

Remove the cap from the vial,
Remove the nebulizer from the packaging,
Attach it to the vial,
Activate the nozzle by pressing twice.

One click on the spray nozzle results in the release of about 4 ml of the solution. Multiplicity of application is 3-4 times a day (regardless of age). The scheme is approximately the same: they ate, brushed their teeth, rinsed or irrigated. If it's not about treating the throat, but about rinsing the mouth, then the duration of the latter is optimal in 30-60 seconds.

Course of application: with inflammation of the gums - strictly 10 days, with the treatment of herpetic form of stomatitis - until the clinical recovery (but no more than 10 days), with tonsillitis and other inflammatory diseases of ENT organs - from 4 to 10 days.

Dosage of ointment

The ointment is applied to a previously treated antiseptic surface, and a dressing or bandage is applied over it. Tampons, impregnated with ointment, fill the fistulas and cavities of purulent wounds.

In phase 1 wound process - once a day, in phase 2, once for 1-3 days. The course of treatment is determined by the rate of purging purulent wounds and tissue regeneration.

In dermatological practice - ointment is applied to the affected areas with a thin layer, several times a day. You can impregnate a sterile bandage and apply to damage (1-2 times a day). Apply up to 6 weeks in a row.

Side effects

There is rarely a local reaction - a burning sensation that goes on alone for a short time (5-20 seconds). This does not require the abolition of the drug.

With increased sensitivity to miramistin, local skin irritation can occur: itching, hyperemia, burning sensation, dry skin.

Overdose

No data available.

special instructions

The mutagenic effect of drugs in the study was not revealed.

Do not allow the product to get into the eyes. Miramistin for eyes is used exclusively after the appointment of a specialist. At the same time about whether you can rinse your eyes with this solution, and how to do it correctly, you must always find out from your doctor. For the treatment of eye diseases, Ocomistin is used based on miramistine.

Since this drug has a wide range of effects, it is prescribed for mixed fungal and bacterial infections. As a rule, this occurs at the first stage of therapy, before the diagnosis is established.

Drug Interactions

In combination with antibiotics, there is an increase in their antibacterial properties.

Reviews

We picked up some reviews of people who used Miramistin:

Catherine. Miramistin is always at hand in the bathroom. An excellent drug, I use for any reason for the whole family-cuts, wounds, stomatitis, ulcers or sores which, sore throat or even if the tooth hurts. Originally recommended to us by his doctor, when his son had chicken pox, and the rashes were even on the mucous in the mouth. Very convenient dispenser, the drug is not consumed much. A large bottle is enough for a long time. And there is no unpleasant taste, for children this is important.
Karina. Miramistin I have been using for a long time, I liked the drug very much. Especially well helped with inflammation in the throat. But recently I bought it and was disappointed, they do not have the effect of treatment (my throat hurt), my daughter caused an allergy, I also had a throat treatment. Previously, did not cause allergies. I had an opinion that the composition of the drug has changed. Very upset. It's a pity the drug was good.
Svetlana. Myramistin was first appointed to my daughter for the treatment of a cold. She drank the medicine for almost a week, but did not notice much improvement. Then I tried to bury it in my ears: this medicine is meant for both the nose, the ears, and, apparently, even for the eyes. I can not say that my ears hurt badly, but there was discomfort. I did not want to go to the doctor, and here's a medicine like at hand. I read the instructions and started to drip. The next day the pain almost passed, only echoes remained. A few days later my ears were in perfect order. It seems to me that the medicine still helps, but, probably, everything depends on the specific disease.

Analogues

Among the structural analogues of Miramistin containing the identical active substance are:

Okomistin.
Miramistin-Darnitsa.
Septomirin.

Before using analogues, consult your doctor.

What is the difference between Miramistin and Chlorhexidine?

These drugs are similar in terms of pharmaceutical effects. However, they are not complete analogues. General properties of the preparations:

They have high activity and effectively kill the pathogenic flora;
Are antiseptics, i.e. are included in one pharmaceutical series.

This concludes their similarity. What is the difference? The drug does not contain chlorine in an explicit form, because it is not as aggressive as Chlorhexidine in the minimum dosage. Therefore, it is the first that is safer. In addition, it has a wider range of therapeutic effects.

So which is better? It is possible to answer unequivocally: Miramistin is better. Answering the question "What is the difference between Miramistin and Chlorhexidine?" It is worth noting:

Less aggressiveness of the first.
Greater opportunities for use (broader).
Fewer contraindications and side effects.

Storage conditions and shelf life

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 ° C. Shelf life 3 years. After the expiration date the preparation is not suitable for use.