Melaxen

width = Melaxen is a drug used to: adapt to the rapid change of time zones; reduction of stress reactions, normalization of circadian rhythms and the process of night sleep; regulation of the sleep-wake cycle, diurnal changes in body temperature and locomotor activity; immunostimulant and pronounced antioxidant.

The active ingredient of Melaxen is a chemical analogue of the biological hormone of sleep - melatonin. Its synthesis is carried out from plant material.

Melatonin is a pituitary hormone involved in the regulation of circadian rhythms (sleep-wakefulness, thermoregulation, motor activity).

Clinical and pharmacological group

A drug used for temporary adaptation disorders.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Melaxen cost? The average price in pharmacies is at the level of600 rubles.

Form of issue and composition

The preparation is produced in the form of round biconvex, coated tablets of white or white and yellow color, containing:

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3 mg melatonin;
Auxiliary components: microcrystalline cellulose, calcium hydrophosphate and magnesium stearate;
Shellac, talc and isopropanol (composition of the shell).

Melaxen tablets are sold in 12 pcs. in blisters, packed in cardboard packs of 1 or 2 pcs.

Pharmacological effect

Melaxen is an analog of the chemical biogenic amine melatonin, which is an adaptogenic preparation. It is synthesized from plant amino acids. Therefore, being an analogue of the synthetic hormone of the epiphysis, Melaxen helps normalize the work of circadian rhythms. This drug regulates the sleep-wake cycle, as well as daily motor activity and changes in body temperature.

The use of Melaxen improves night sleep, improving its quality and speeding up the process of falling asleep. Patients who use this drug significantly reduce the number of nocturnal awakenings do not cause a feeling of sluggishness and weakness in the morning awakening.

The drug improves well-being after awakening, and dreams become brighter and emotionally saturated. In addition, the drug contributes to the rapid adaptation of the organism to the change of time zones, reducing the risk of stress. In addition, the drug will oppress the secretion of gonadotropins and other hormones of adenohypophysis (much less) - corticotropin, thyrotropin and somatotropin.

Melaxen is characterized by antioxidant and immunostimulating effects, without causing addiction and dependence.

Indications for use

The drug is used in the following cases:

As a hypnotic.
As adaptogen for the normalization of biological rhythms.

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Contraindications

There are a number of contraindications to the appointment of a medicinal product:

Severe renal dysfunction;
Chronic renal failure;
Diabetes;
Lymphoma;
Epilepsy;
Lymphogranulomatosis;
Autoimmune diseases;
Myeloma;
Leukemia;
Allergic reactions;
Pregnancy and lactation;
Hypersensitivity to the drug.

Use in pregnancy and lactation

The drug is forbidden to use during pregnancy and breastfeeding. Differences in the concentration of hormones can affect the development of the fetus in a negative way.

Women who want to become pregnant should take into account Melaxen's ability to display a mild contraceptive effect.

Dosage and route of administration

The instructions for use indicate that Melaxen should be taken orally.

As a hypnotic, appoint ½-1 tablet once a day for 30-40 minutes before bedtime.

As an adaptogenic agent, Melaxen is recommended to start taking 1 day before the change of time zones and continue taking the next 2-5 days. The recommended dose is 1 tablet 30-40 minutes before bedtime. In some cases, an increase in the daily dose of up to 2 tablets is possible.

Side effects

When using Melaxen, there may be side reactions from some organs and systems:

Digestive system: diarrhea, nausea, vomiting;
Central nervous system: headache, morning drowsiness;
Other: swelling in the first week of therapy, allergic reactions to the components of the drug.

Overdose

The likelihood of an overdose is minimized when using the Melaxen in the allowable dosages. Among the possible symptoms of overdose are:

loss of consciousness;
pain behind the sternum;
nausea and vomiting;
stomach ache;
confusion of consciousness;
decrease in body temperature.

Symptomatic treatment is used to eliminate these symptoms. It is necessary to perform gastric lavage. In case of emergency, hospitalization in hospital is indicated.

special instructions

During the use of the drug should be avoided staying in bright light.
It is necessary to inform women who want to become pregnant, about the presence of a weakly expressed contraceptive effect in the drug.

During the treatment period it is necessary to refrain from driving and other activities potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

Drug Interactions

Incompatible with MAO inhibitors, GCS and cyclosporine.

It is not recommended to take together with hormonal drugs.

With the simultaneous use of melatonin enhances the effect of drugs that have a depressing effect on the central nervous system, and beta-blockers.

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Reviews

We picked up some reviews of people who took the drug Melaxen:

Michael. Really cures insomnia, but I suffered six months, with falling asleep. I drank a couple of weeks, get up early in the morning, fall asleep well, and sleep by the way is so strong, healthy. I would say quality, even dreams that somehow dream. Vobschem I sleep perfectly. I forgot about insomnia.
Vyacheslav. When flying from west to east, it helps me get used to another time zone faster. I start taking the day before departure, I drink a pill on our time in the day and fly out the next day. Already on our far east I drink already before going to bed at night. I can say for sure that it is much easier to get used to the change of time.
Lyudmila. It did not immediately affect me, for three days there was absolutely no effect at all. The regime changed, after a maternity leave to work it was necessary to leave. Well, in principle, melaxen helped, with time, could quickly fall asleep. There were no side effects, it is normally tolerated.
Sergei. I went to the pharmacy just to ask about sleeping pills, they said that without a prescription it is not allowed. And from insomnia without a prescription, only this, melatonin, showed Melaxen. The choice was not taken a pack, and began to drink before going to sleep, as they said. I did not even think that it would be like that, but after five days I really began to fall asleep better, now I sleep well without it.

Analogues

Most of the similar substitutes are inexpensive, but their efficiency is less.

Vita-Melatonin. In addition to the active component contains a vitamin complex, which has a general strengthening effect and increases the immune status.
Melaritm. Domestic substitute exactly repeats the composition and characteristics of foreign pharmaceuticals. The Russian product is more affordable at a price of 320 rubles for a small package (12 tablets) and 400 for a large package (24 tables).
Circadian. Acts like Melaxen. It is not acceptable to combine it with fluvoxamine or use people with impaired glucose / lactose absorption functions.
Sonnivan. Also inexpensive drug produced in Russia. Sonnovan is recommended for people who need long-term treatment of insomnia or stabilization of the psycho-emotional state.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep the medicine in a dry place inaccessible to sunlight. The optimum temperature regime is from 10 to 30 ºС. If these conditions are met, the shelf life is 4 years.