How to take hepatoprotector Heptor

The heptor is a hepatoprotector, in addition it can suppress a depressive state, it also has a neuroprotective, regenerating action.

This medicine will help to cleanse the body of toxic products. It is able to stimulate the production by the patient's organism of a specific biologically active substance ademethionine, which participates in most biological reactions as a methyl group donor, also being the basis for antitoxic connections.

On this page you will find all information about Geptor: the full instruction on the application to this medicinal medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Heptor. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Hepatoprotector, has antidepressant activity.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is the heptor? The average price in pharmacies is at the level of1 200 rubles.

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Form of issue and composition

The medicine is produced in the form of oblong tablets, covered with a yellow enteric coating. In the section, two layers are visible.

Also, the preparation is produced in the form of a powder - lyophilizate for the preparation of a solution. It is intended for intramuscular and intravenous administration.

• The main active substance is S-adenosylmethionine (400 mg).

As auxiliary substances, mannitol, microcrystalline cellulose, crospovidone and magnesium stearate are used.

Pharmacological effect

Heptor - hepatoprotective drug with antidepressant activity. Heptor has detoxification, antioxidant, regenerating, neuroprotective and antifibrozing effects.

Heptor contains the active component ademetionine (S-adenosyl-L-methionine), which is included in a number of biochemical processes in the body, and also stimulates the production of endogenous ademetionine. Ademethionine is present in virtually all tissues and body fluids, it takes part in biochemical reactions as a methyl group donor. In particular, ademetionine participates in the process of methylation of phospholipids of the cell membrane layer (transmethylation), and is also a precursor of thiol compounds, including taurine, cysteine, glutathione and CoA. Ademethionine plays an important role as a precursor of polyamines, including putrescine (which stimulates cell regeneration and proliferation of hepatocytes), spermine and spermidine (which are included in the structure ribosomes).

Tablets of the preparation Geptor are covered with an enteric coating - the active component is released in the duodenum.

Indications for use

Heptor is used to treat primary depressive conditions, as well as secondary, caused by somatic diseases, alcohol or drug dependence. It is prescribed for relief of alcohol and narcotic withdrawal syndrome.

It is used in the treatment of patients suffering from hepatitis caused by alcohol, viral diseases, or drugs, including antibiotics, chemotherapy, antituberculosis and antiviral agents, tricyclic antidepressants, hormonal contraceptives.

It is used in maintenance therapy for cirrhosis of the liver, as well as in precirototic conditions, encephalopathy of any origin, predominantly secondary.

Contraindications

Heptor can not be used on the first and second trimester of pregnancy and during lactation. Also, this drug is contraindicated for use in children who are under 18 years old.

Do not apply heptor to patients who are hypersensitive to any of the components of the drug.

Application in pregnancy and lactation

In the first and second trimesters of pregnancy, ademetionine is used only in case of emergency, when the expected benefit for the mother exceeds the potential risk to the fetus. The use of ademetionine in high doses in the III trimester of pregnancy did not cause any undesirable effects.

The use of ademetionine in the period of breastfeeding is possible only if the expected benefit for the mother exceeds the potential risk for the child.

Instructions for use

The instructions for use indicate that the method of administration of the preparation of heptor in the form of lyophilizate: intramuscularly (intravenously) or intravenously (iv), the tablets are taken orally.

1. When administered orally, the daily dose is 800-1600 mg.
2. For IV or IM, the daily dose is 400-800 mg.
3. Duration of treatment is determined individually depending on the severity and course of the disease.

In elderly patients, treatment is recommended starting at the lowest recommended dose, taking into account the reduction hepatic, renal or cardiac function, the presence of concomitant pathological conditions and the use of other medicinal products means.

Side effects

Usually the medicine is well tolerated. Sometimes there is discomfort in the stomach, which is due to the acidic pH of the main active substance. This side-effect disappears by itself, and there is no need to cancel treatment or use additional therapy.

Sometimes the manifestation of an allergic reaction is possible.

Overdose

There is no information about taking the drug at a dosage exceeding the therapeutic norm.

special instructions

1. In liver cirrhosis, which is associated with hyperosotemia, systematic monitoring of azotemia is necessary.
2. It should be taken into account that Heptor produces a tonic effect. In this regard, its use before bedtime is not recommended.
3. The drug solution must be prepared immediately before use. In cases of changing the color of the lyophilisate, it can not be used.
4. During prolonged treatment, the serum urea and creatinine levels in the blood should be determined.
5. When Hepter is prescribed to patients with bipolar disorders, it is necessary to take into account that there is information about the transition during depression therapy to mania / hypomania.

Drug Interactions

There is no information on the manifestation of the drug drug interaction.

Reviews

We picked up some of the people's feedback on the drug Heptor:

1. Ildus. Heptor and heptral are exactly the same, I drink long after viral hepatitis A, the wonderful drug is very good restores the liver, except it completely removes depression and very well soothes, but you can not drink at night!
2. Maria. I have hepatitis c (identified 4 years ago), the indicators are still quite good. At the expense of the heptor consulted with the hepatologist in the "center of the study of the liver" (via the Internet), she replied that the drug is decent, drank the course (to drink a month or two months, it still works), passed the tests: general and biochemistry for liver. The hemoglobin rose and albumin entered the norm, it was lowered all four years. And still the heptor removes depression, activity increases, mood improves. There were no pills, but I'm 70 years old and have sores of all sorts of bouquets. As the therapist told me: "not even a bouquet, but an entire armful).
3. Andrei. My uncle was sick with cirrhosis of the liver. I went to doctors for a long time, then he was appointed to take heptor before meals on the day about 3 tablets in one month. Strangely enough, my uncle began to get better, then he was once again prescribed this course and painted a strict diet. Now he is walking healthy.
4. Igor. I consider Geptor a fairly effective drug, although at the beginning of treatment I received the course of Amitriptyline and refused he could not, had to lie down on the day hospital, because he felt at the time of taking the drugs disgusting. Nauseated, my head ached, but I slept soundly and became more efficient. At the end of the course returned to normal life, the doctor recommended that after six months again drink a course for prevention.

Analogues

The only structural analogue of the drug is Heptral. Both drugs have the same active substance, so almost nothing is different. Heptral is also available in the form of tablets and powder for the preparation of a solution. When a patient has a question about which medicine to choose, it is difficult to give advice.

Analogues-hepatoprotectors, which are not structural with respect to Gepor, include:

1. Carnithen. A drug based on levocarnitine. This compound of natural origin, close to the vitamins of group B. Produced in the form of tablets and solution for injection. Assigned with a deficiency of carnitine in the body. Possible use in angina pectoris, myocardial infarction.
2. Hepadiff. The drug, consisting of 5 main components: adenosine, riboflavin and pyridoxine, cyanocobalamin and carnitine. Each of these components has its own effect on the liver, having a beneficial effect. As a rule, the medicine is used for cirrhosis and hepatitis of various etiologies, as well as for neutralizing the toxic effect on the liver of certain medicines. The medicine is available in capsules and ampoules with powder for solution preparation and can be prescribed for adults and children over 7 years of age.
3. Gepabene. Herbal preparation on the basis of the extract of milk thistle and smokey. The compounds that make up these plants normalize the outflow of bile, promote the regeneration of the cells of the organ. The medicine is used for inflammatory processes of bile ducts, dyskinesia, cholecystitis. Issued in capsules, is allowed to children from 6 years of age.
4. Livedovs. Medication based on ursodeoxycholic acid. It is used to dissolve cholesterol stones, as well as for the treatment of cirrhosis and reflux gastritis. The medication is available in the form of tablets, has many side effects.
5. Karsil. Medication, along with the auxiliary components, contains silymarin. This compound of vegetable origin, extracted from milk thistle, has a regenerating effect on liver cells, prevents the penetration of organ toxins. The medicine is used for cirrhosis, toxic effects, hepatitis, for the prevention of liver diseases. The drug is available in the form of a dragee and is approved for use by children from 12 years of age.
6. Essentiale Forte N. The drug is based on phospholipids, which strengthen the envelope of liver cells. It is used for hepatitis, cirrhosis, liver necrosis, after operations for the prevention of complications, with toxic poisoning and toxicosis of pregnant women, neurodermatitis and other skin diseases caused by disruption in work liver.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep the tablets in their original packaging, protect them from direct sunlight. The temperature should be between 15 and 25 degrees.

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