Diclofenac Candles: Instructions for Use

Diclofenac belongs to the anti-inflammatory series of drugs. Does not contain hormones or their analogues.

The medicine in the form of candles is used in the therapy of many diseases, including gynecological ones. These suppositories simultaneously anesthetize, remove edema and fight with tumors and infections.

On this page you will find all information about Diclofenac: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used candles Diclofenac. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

NSAID, a derivative of phenylacetic acid.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much are the diclofenac suppositories? The average price in pharmacies is at the level of100 rubles.

Form of issue and composition

One suppository contains:

• active substance: diclofenac sodium 50 mg or 100 mg; auxiliary substances: cetyl alcohol, semisynthetic glycerides - a sufficient amount for obtaining a suppository with a mass of 2 g.
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White or white with a yellowish tinge of the suppository cylindroconical shape. On the cut, an air and a porous rod and a funnel-shaped depression are allowed.

Pharmacological effect

Anti-inflammatory, analgesic, antipyretic. The mechanism of action is due to the suppression of biosynthesis of prostaglandins by inhibition of cyclooxygenase, a decrease formation of kinins and other mediators of inflammation and pain, stabilizing effect on lysosomal membranes.

With rheumatic diseases reduces swelling, flushing and pain in rest and motion, morning stiffness and swelling of the joints, improving their functional capacity. Relieves migraine attacks.

Indications for use

What helps diclofenac candles? Here are the main indications for use:

1. Bursits;
2. Ankylosing spondylarthrosis;
3. Thrombophlebitis;
4. Inflammation of the joints, muscles, ligaments;
5. Osteoarthritis;
6. Neuralgia;
7. Arthritis (rheumatoid, infectious, gouty, traumatic);
8. Radiculitis;
9. Myalgia;
10. Myositis (aseptic inflammation of skeletal muscles);
11. Gout;
12. Herniated or protrusion of intervertebral discs.

In combination with antispasmodics, suppositories can be used for hepatic or renal colic to relieve pain.

Additionally rectal suppositories can be prescribed for other pathologies accompanied by pain and inflammation: postoperative period, acute pains in the back or spine, dental and headaches, infectious ENT diseases with a painful course.

Contraindications

Contraindications to the use of candles Diclofenac are:

• exacerbation of peptic ulcer;
• bronchial asthma;
• patient's age up to 16 years;
• hypersensitivity to the active ingredient or excipients;
• period of aortocoronary shunting;
• cracks in the mucosa;
• erosion;
• hemorrhoids;
• bleeding not associated with menstruation;
• proctitis;
• colitis;
• hyperkalemia;
• renal, cardiac or hepatic insufficiency.

With special care it is necessary to apply the drug in the following diseases and conditions:

• liver disease;
• diabetes;
• alcoholism, a tendency to other bad habits (including smoking);
• ischemia of the heart;
• elderly patients;
• weakened organism;
• insufficient body weight;
• stomach ulcer;
• Crohn's disease;
• low volume of blood circulation;
• hypertonic disease;
• infection Helicobacter pylori;
• vascular disease.

The simultaneous use of Diclofenac with medicines requires attention:

• serotonin reuptake inhibitors;
• anticoagulants;
• antiplatelet agents;
• glucocorticosteroids;
• nonsteroidal anti-inflammatory agents.

Application in pregnancy and lactation

There is insufficient data on the safety of diclofenac in pregnant women. Therefore, the appointment in I and II trimesters of pregnancy is possible only in those cases when the expected benefit for the mother exceeds the potential risk to the fetus. Diclofenac (as other inhibitors of prostaglandin synthesis) is contraindicated in the third trimester of pregnancy (possibly suppression of uterine contractility and premature closure of the arterial duct in the fetus).

Despite the fact that diclofenac is excreted in breast milk in small amounts, application during lactation (breastfeeding) is not recommended. If it is necessary to use lactation, breastfeeding should be discontinued.

Since diclofenac (as well as other NSAIDs) can have a negative effect on fertility, it is not recommended for women planning pregnancy.

Patients undergoing examination and treatment for infertility, the drug should be canceled.

Instructions for use

The instructions for use indicate that the diclofenac suppositories are intended for rectal administration, as deep as possible after the act of defecation.

• Usually appoint 50 mg twice a day or 100 mg once a day. The maximum dose for daily use is 150 mg. The duration of treatment is determined individually.
• With migraine: 100-150 mg with the first attacks.

Suppositories are injected entirely, without cutting into parts; this can lead to impaired absorption.

Side effects

Diclofenac in the form of candles smoothes a negative effect on the digestive system, kidneys, liver, but does not protect against all side effects inherent in this group of drugs.

Unpleasant sensations appear in the intestines:

1. Nausea;
2. Abdominal pain;
3. Burning at the injection site suppository;
4. Flatulence;
5. Constipation or diarrhea;
6. Unpleasant taste in the mouth.

Side effects increase with prolonged use of suppositories, overdose, combination with other nonsteroidal anti-inflammatory agents, with individual intolerance to the components.

Overdose

When an overdose appears:

• headache;
• high blood pressure;
• convulsions;
• noise in ears;
• vomiting and nausea;
• pain in the abdomen.

special instructions

Before you start using the drug, you should carefully read the instructions to it, there are a few special instructions that should be taken into account:

1. The possibility of using the drug for pregnant women in the I and II trimester of pregnancy is determined by the doctor, comparing the expected benefit to the mother and the potential risk to the fetus.
2. In the case of prolonged use of Diclofenac suppositories, laboratory monitoring of blood coagulation, functional activity of the kidneys and liver is mandatory.
3. Parallel use of medicines from a group of non-steroidal anti-inflammatory drugs requires a reduction in the dosage of suppositories of diclofenac.

It is not recommended to perform work associated with increased concentration of attention or speed of psychomotor reactions in connection with the possible development of side effects from the central nervous system.

Drug Interactions

1. Reduces the effect of diuretics, against the background of potassium-sparing diuretics increases the risk of hyperkalemia.
2. When combined, increases the plasma concentration of lithium, digoxin.
3. The concentration of diclofenac in the plasma decreases with the simultaneous use of acetylsalicylic acid.
4. With the simultaneous administration of anticoagulants (including warfarin), antiplatelet agents (including acetylsalicylic acid, clopidogrel) and itrombolitic drugs (including increased risk of bleeding (chap granite).
5. Reduces the effect of hypoglycemic, hypotensive and hypnotics.
6. When combined with other NSAIDs and glucocorticoid drugs (including prednisolone) increases the likelihood of side effects (gastrointestinal bleeding).
7. Sharing with paracetamol, cyclosporine and gold preparations increases the risk of developing nephrotoxic effects.
8. Selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline) increase the risk of bleeding in the gastrointestinal tract.
9. Simultaneous administration with colchicine and corticotropin increases the risk of bleeding in the gastrointestinal tract.
10. Drugs that block tubular secretion (including verapamil, nifedipine, diltiazem), increase the concentration in the plasma of diclofenac, thereby increasing its effectiveness and toxicity. Antibacterial agents, quinolone derivatives increase the risk of seizures.

Reviews

We picked up some reviews of people about the candles Diclofenac:

1. Marina. Used in the treatment of cystitis in combination with other agents. The therapy lasted 10 days and ended well. There were side effects, but it's hard to tell from which medicine. I use candles periodically, as soon as the cystitis shows itself.
2. Veronica. I got an interesting situation. Appealed to the gynecologist with suspicion of inflammation. There was a delay in menstruation, characteristic for inflammation discharge, aching pain in the abdomen, lower back. The doctor examined, said there was nothing like that. As a result, she appointed herself a candle Diclofenac. Successfully healed for 5 days. On this my problem disappeared. There were unpleasant sensations in the abdomen, a chair was broken, a little nauseated. Everything came back to normal after the drug was discontinued for 3 days. Effective, effective tool. I am glad that it works in several directions at once. Do not have to stuff yourself with different medications.
3. Ksyusha. I like candles, only they help, because pains are such that even hang. I use them only during menstruation for a long time, used to help me better! Any medicine is harmful, but then you must decide for yourself what is better - to suffer pain or suffer from side effects!

Analogues

According to the active substance and therapeutic effect, candle-like products Voltaren, Diklovit are similar for Diclofenac suppositories.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The drug is usable for three years from the date of release printed on the package, after the expiration date the drug is not stored and is not used, as it is subject to disposal.

Store Diclofenac can be strictly at a temperature of 15 to 25 degrees Celsius, outside the reach of children. The storage location must be protected from moisture and direct sunlight.

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