Instructions for use Antigrippin

width = Antigrippin is a combined preparation that has anti-inflammatory, antipyretic and antihistamine action, and also facilitates the course of influenza and ARVI.

Reception of the drug facilitates the rhinitis, removes the swelling of the nasal mucosa with rhinitis. Antigrippin contains paracetamol, ascorbic acid and chlorpheniramine maleate. These substances, combining their therapeutic properties, exert an enhanced effect of the drug on the body.

On this page you will find all information about Antigrippin: the full application instruction for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Antigrippin. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug for symptomatic therapy of acute respiratory diseases.

Conditions of leave from pharmacies

Released without a doctor's prescription.

Price list

How much does Antigrippin cost? The average price in pharmacies is at the level of320 rubles.

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Form of issue and composition

The given preparation is made:

in the form of an oral, water-soluble powder Antigrippin in bags of 5 grams of No. 10 in the secondary packaging;
in the form of tablets Antigrippin effervescent in plastic cases №10, blisters number 10 or strips №2, №4, №6;
in the form of tablets Antigrippin effervescent with the taste of grapefruit or raspberries in plastic cases number 10, blisters number 10 or strips number 2, number 4, 36;
in the form of effervescent tablets for children Antigrippin in plastic canisters №10, blisters №10 or strips №2, №4, №6.

Composition depends on the form of release:

1 gustatory effervescent tablet includes paracetamol 500 mg, ascorbic acid 200 mg, chlorphenamine maleate 20 mg. Additionally contains: sodium bicarbonate, citric acid, povidone, sodium carbonate, sorbitol, sodium lauryl sulfate, macrogol, riboflavin-5-phosphate sodium, and sodium saccharinate, raspberry aroma "Malina flavor enhancer and beetroot powder (for crimson tablets) or taste corrector, lemon flavorings "Lemon" and grapefruit "Grapefruit" (for grapefruit tablets).
1 packet of oral powder includes paracetamol 500 mg, ascorbic acid 200 mg, chlorphenamine maleate 20 mg. The pharmaceutical composition of the powder further includes: sodium hydrogen carbonate, citric acid, povidone, acesulfame potassium, sorbitol, sodium cyclamate, sucrose, aspartame, docusate sodium, as well as chamomile extract (for chamomile powder) or lime flavoring "Lime caramel and honey (for honey-lemon powder).
1 effervescent tablet for children includes paracetamol 250 mg, ascorbic acid 50 mg, chlorphenamine maleate 3 mg. Additionally contains: sodium bicarbonate, citric acid, sodium saccharinate, sorbitol, sodium carbonate, povidone, silicon dioxide, macrogol, and fruit flavor "Red Fruits".
1 effervescent tablet includes paracetamol 500mg, ascorbic acid 200mg, chlorphenamine maleate 20mg. Additionally contains: sodium bicarbonate, citric acid, sodium saccharinate, sorbitol, sodium carbonate, povidone, sodium lauryl sulfate, macrogol, as well as lime flavoring "Lime".

Pharmacological effect

Antigrippin is a complex preparation that surpasses many analogues due to the successful combination of several active components:

Ascorbic acid (vitamin C) is a powerful antioxidant. It helps to restore the defenses of the body, participates in the normalization of oxidation - reducing processes, reduces the permeability of small vessels and has a pronounced immunomodulating action.
Paracetamol - known to everyone since childhood, is an antipyretic and analgesic and anti-inflammatory agent. To date, according to experts from the World Health Organization, he is one of the safest of the group of non-steroidal drugs with anti-inflammatory effect.
Chlorphenamine. This component quickly removes the symptoms of inflammation of the mucous membranes of the upper respiratory tract, eliminates allergy manifestations (sneezing, lacrimation, nasal congestion). In addition, it has a mild calming effect, helps to establish sleep and adjusts the body to mobilize forces in the fight against the virus.
Diphenhydramine is a component against allergies. Actively reduces the permeability of the walls of the vessels, removes the swelling of the mucous membranes and removes the feeling of perspiration in the throat. Its presence in the composition of the drug allows you to quickly cope with allergic reactions.
Rimantadine is an active agent against influenza A virus. It blocks its ability to penetrate into cells and disrupt their functioning, preventing the virus from spreading through the body. With respect to the viral disease type B has a powerful antitoxic effect. Do not stay in the body: completely excreted by the urinary system after three days after taking.
Calcium gluconate strengthens the vascular wall, helps to stop the inflammatory process in the body.
Loratadine is a modern antihistamine. Reduces the level of release of serotonin, histamine. It removes itching, swelling, inflammation and does not cause drowsiness.

Thanks to the ingredients described above, Antigrippin quickly copes with all the signs of acute respiratory illness (temperature, headache, joint and muscle pain, fever). The drug is recommended to be taken in the first hours of the manifestation of the disease, so you can significantly shorten its duration and prevent the risk of complications.

Indications for use

Antigrippin is prescribed for the symptomatic treatment of influenza and acute respiratory diseases, which accompanied by an increase in body temperature, headaches, rhinorrhea, myalgia, sore throat and mucosal edema shell of the nose.

Antigrippin is also used for bacterial, viral and allergic rhinitis.

Contraindications

Antigrippin is contraindicated in stomach ulcers, hypersensitivity, severe violations of the liver and kidneys, closed-angle glaucoma, prostatic hyperplasia, anemia, viral hepatitis, phenylketonuria, leukopenia and alcoholism. Also, this medicine can not be taken during pregnancy and lactation. Effervescent tablets are not prescribed for children under three years of age.

The drug should be taken with caution elderly patients, as well as those who suffer from hyperoxalitis, alcoholic hepatitis and progressive malignant diseases. Antigrippin is contraindicated in children younger than one year old

Application in pregnancy and lactation

The drug is contraindicated for use during pregnancy. If it is necessary to use the drug during lactation it is recommended to solve the problem of temporary interruption of breastfeeding.

Instructions for use Antigrippin

The instructions for use indicate that Antigrippin is taken internally.

Children from 3 to 5 years on 1/2 tablets 2 times a day;
Children from 5 to 10 years, 1 tablet 2 times a day;
Children from 10 to 15 years no 1 tablet 2-3 times a day.

The tablet should be completely dissolved in a glass (200 ml) of warm water (50-60 ° C) and the resulting solution immediately drink. It is better to take the drug between the methods of poverty. The interval between doses should be at least 4 hours. Duration of admission without consulting a doctor is no more than 5 days when prescribed as an anesthetic and 3 days in quality

In patients with impaired liver or kidney function, the interval between doses should be at least 8 hours.

Instruction for powder

Inside. Adults and children over 15 years - 1 packet 2-3 times a day.

The contents of the sachet should be completely dissolved in a glass (200 ml) of warm water (50-60 ° C) and the resulting solution immediately drunk. It is better to take the drug between meals. The maximum daily dose is 3 sachets. The interval between doses should be at least 4 hours.

Side effects

In most cases, with the use of Antigrippin in recommended dosages, side effects do not develop. In isolated cases, there may be:

Anemia, hemolytic anemia (hematopoiesis);
Skin rashes, hives, itching, swelling of Quincke (allergic reactions);
Feeling tired, headache (central nervous system);
Pain in the epigastric region, nausea (digestive system);
Hypoglycemia (endocrine system);
Urinary retention, metabolic disorders, hypervitaminosis, dry mouth, fever, paresis of accommodation, drowsiness (other).

Overdose

Symptoms of overdose often develop when the active components of the drug enter the body. In case of individual intolerance to paracetamol, the symptoms of overdose develop after 5-10 hours from the moment of using the medication.

The clinical picture of an overdose includes such symptoms:

vomiting and nausea;
increased sweating;
total or partial loss of appetite;
stool disorders (diarrhea);
a pain in the abdomen that does not have a clear localization.

If there was an overdose of chlorphenamine, the clinical picture includes such symptoms:

headache;
depressive conditions;
increased emotional excitability;
insomnia;
dizziness;
convulsions.

When symptoms of an overdose appear, it is recommended to stop using the drug and seek medical advice. In such cases, symptomatic therapy is indicated.

special instructions

When taking it is necessary to take into account the toxic effect of paracetamol on the liver, as well as the effect of vitamins on proliferative diseases:

An increase in the side effect of paracetamol on the liver is observed with alcoholic hepatosis;
To avoid toxic effects on the liver, do not combine paracetamol with alcohol or use the drug for people who are prone to alcoholism;
When using products containing vitamins, persons suffering from proliferative and metastatic tumors may worsen the course;
With prolonged admission, it is necessary to monitor the condition of peripheral blood, liver and kidneys;
When concomitantly taking metoclopramide (Cerucal), domperidone (Motilium), colestyramine (Questran) it is recommended to consult a doctor;
When you receive possible distortion of the results of laboratory data on the level of glucose and uric acid in the blood, the amount of bilirubin, the activity of transaminases and lactate dehydrogenase;
Antigrippin contains sugar, which must be taken into account for people with diabetes.

Drug Interactions

The drug antigrippin and alcohol are incompatible, since ethyl alcohol enhances the effect of the antihistamine component. The use of this medication in combination with antidepressants, antipsychotic and anti-Parkinsonian drugs, leads to the development of adverse reactions from organs and systems.

Simultaneous use of paracetamol and barbiturates leads to a decrease in the therapeutic effect of paracetamol, and accelerates the excretion of ascorbic acid.

Reviews

In most cases, reviews about Antigrippin, including all of its dosage forms, are positive. Indeed, this complex of medicinal substances is quite effective for the removal of symptomsdisease states of infectious-inflammatory etiology (flu, ARVI), but needs proper application and strict adherence to the dosage regimen.

Negative manifestations during the use of Antigrippin were most often observed when the dosages were exceeded or the recommended duration of treatment,personal sensitivitypatient to its ingredients.

Analogues

Analogues of Antigrippin are:

For active substances: Antiflu Kids, FlUZiOZ-F;
By the mechanism of action: Solpadein, Iphimol, Xumapar, Dolaren, Antiflu, Caldrex, Caffetin, Grippostad, Padewiks, Rankof, Paracetamol, Daleron, Apap, Panadol, Gevadal, Novalgin, Coldfrey, No-shpalgin, Teraflu, Pentalgin, Strymol, Prohodol, Rinzasip, Saridon, Femizol, Flukoldeks, Safiston, Flukomp, Ajikold, Efferalgan.

Before using analogues, consult your doctor.