From this article you will learn: Concorda tablets from what help, what active ingredient is a part of this drug, what diseases it is prescribed by doctors, how it affects the human body and its health.
- Mechanism of action
- Mechanism of action
- Use at increased pressure
- Use in heart failure
- Use in angina
- Use in myocardial infarction
- Use to reduce heart rate
Concor is an effective drug whose active ingredient is bisoprolol. According to cardiologists, this is one of the most high-quality preparations of bisoprolol.
Bisoprolol refers to beta-blockers, which are prescribed most often for treatment:
- arterial hypertension( abbreviated AH);
- angina;
- myocardial infarction;
- tachycardia( rapid heart rate);
- heart failure( CH).
This application is due to the fact that concor reduces blood pressure( BP) and heart rate( heart rate).
Concor - a preparation with many positive properties. However, its application can not be started independently. Like any medicine, it has its own indications and contraindications for admission, which can be detected only by a doctor. Self-medication with a medicine can be dangerous for a person.
Assign concor to cardiologists and therapists.
Mechanism of action
Beta-blockers are drugs acting on beta-adrenergic receptors located mainly in the heart and bronchi. There are several types of these receptors. Bisoprolol acts on the species that is placed in the heart.
The most significant effect of bisoprolol is a slowing of the heart rate at rest and during exercise. The force of the contractions of the heart decreases after applying the concore, which lowers blood pressure.
The action of the concore leads to less use of energy by the heart for pumping blood throughout the body. With heart failure, when the contractile capacity of the heart is significantly worsened, it facilitates its work.
Angina( pain in the heart) occurs when the myocardium( cardiac muscle) does not receive enough oxygen. Concor prevents her attacks, because it reduces the burden on the heart, reducing his need for oxygen.
Use with increased pressure
Concor may be used to treat AH both as monotherapy and in combination with other agents. Doctors rarely recommend a drug for starting treatment of elevated blood pressure. Most often it is prescribed to patients who failed to achieve an adequate reduction in blood pressure with the help of other drugs( angiotensin-converting enzyme inhibitors, thiazide diuretics, calcium channel blockers).
Bisoprolol blocks beta 1 -adrenergic receptors, which are located in the heart, which leads to a decrease in heart rate and a decrease in heart rate. This causes a decrease in blood pressure, which helps to prevent the development of strokes, heart attacks and kidney damage.
Mechanism of action of beta-blockers on the heart Assign concor with AH first in a dose of 2.5-5 mg once a day. Based on the degree of decrease in blood pressure and the level of heart rate, this dose can be gradually increased at an interval of about 2 weeks, 2.5 mg, up to 20 mg per day. If there are side effects from use, you need to lower the dose or cancel the appointment. But to raise or lower the dose of a medicine, as well as to cancel its reception, it is possible only after consultation with the doctor.
Use in heart failure
Due to a decrease in heart rate and blood pressure, concor reduces heart function and myocardial oxygen demand. This is very useful for heart failure, so bisoprolol is often included in the combined treatment of this disease. However, the remedy due to a decrease in the strength of the heartbeats can cause a short-term worsening of the symptoms of heart failure, which usually quickly pass. But doctors recommend appointing with CON concor starting at a low dose - from 1.25 mg per day for 2-4 weeks. With good tolerability, the dose can be increased to 2.5 mg. The next increase to 5 mg per day can be done after 2-4 weeks.
If, in the treatment with concorom, worsening symptoms of heart failure( increased dyspnea, increased edema on the legs), its dose should be reduced or temporarily canceled, and the dose of the diuretic taken is increased. After the improvement of the condition, an attempt should again be made to use the drug, since it has been scientifically proven that bisoprolol reduces the need for inpatient treatment and the risk of death in heart failure.
Use in angina
All beta-blockers, including concor, improve the supply of cardiac muscle oxygen, reducing heart rate and blood pressure. The fact is that the heart itself, unlike other organs, is not supplied with blood at the moment of its contraction( systole), but during its relaxation( diastole).The lower the heart rate, the longer the diastole and the better the blood supply to the heart.
Doctors believe that beta-blockers are the main drugs for long-term prevention of heart pain in ischemic disease. This view is due to the fact that funds from this group, including concor, reduce mortality in patients with coronary heart disease, myocardial infarction and heart failure.
At the time of an attack of angina, Concor does not relieve the pain syndrome. To do this, use other drugs - for example, nitroglycerin. The action of bisoprolol is to prevent similar seizures and increase exercise tolerance.
Application for myocardial infarction
Beta-blocker therapy is the standard treatment for myocardial infarction. Scientists and doctors recommend the use of the drug to begin in all patients with this disease, without contraindications to its use. The advantages of beta-blockers for patients with myocardial infarction include anti-ischemic, antihypertensive, antiarrhythmic and antithrombotic effects.
Most scientific evidence has confirmed the useful properties of concor, the application of which is associated with a reduction in mortality from myocardial infarction, prevention of repeated heart attacks and heart rhythm disturbances. Clinical recommendations recommend taking this drug for at least 3 years after myocardial infarction.
Use to reduce the heart rate
Sometimes doctors prescribe concor to reduce heart rate - for example, if the patient has atrial fibrillation( cardiac rhythm disturbance leading to uncoordinated atrial contractions).This drug does not restore the normal rhythm of contractions of the heart, it just slows them down.
The medication is prescribed after restoration of the normal heart rhythm to prevent the recurrence of the episode of atrial fibrillation.