An increased level of cholesterol in the blood leads to the development of atherosclerosis. This pathology involves the use of medications. Therapy with the use of statins begins. They help to reduce artificially the content of cholesterol. What are statins from cholesterol, what drugs are the most effective and safe - we will consider in more detail.
- Statins - what is it?
- Overview of preparations
- Atorvastatin
- Wazilip
- Atoris
- Roxer
- Rosart
- Deadlyl
- Rosacard
- Simvastatin
- Rosuvastatin
- Natural statins from cholesterol
- The benefits and harm of statins
- Contraindications
Rapid reduction of cholesterol by folk remedies Table of cholesterol in the blood of men Useful products - cleansing vessels and lowering cholesterol How to quickly lower cholesterol in the blood without drugs The level of cholesterol in adults and children - a table by age
Statins - what is it?
Statins are a group of drugs that are designed to lower cholesterol in the blood. But drugs do not directly affect him. They affect the functioning of the liver, inhibiting the release of the enzyme, which is involved in the production of cholesterol.
In the human body are its components - lipoproteins. They have a high and low density. If the metabolic processes are not violated, the lipoproteins do not pose a health hazard. But excessive production of cholesterol promotes the formation of plaques, which leads to the development of serious diseases.
Statins are aimed at reducing the number of cholesterol carriers to tissues. At the same time, the number of receptors for low-density lipoproteins on hepatocytes increases. Namely, they carry cholesterol in the opposite direction - from the bloodstream to the liver. Thanks to these drugs, the production of cholesterol is normal. Their use helps bring its content back to normal.
Important! At what cholesterol take statins? They are necessary for a person at a level above 5 mmol / l. After myocardial infarction, in severe cardiovascular diseases, the target values of cholesterol content decrease.
Overview of preparations
Consider statins, the effectiveness and safety of which is confirmed by clinical studies.
Atorvastatin
These are the most effective pills that help normalize cholesterol levels and prevent problems with the cardiovascular system. According to statistical data, the use of atorvastatin reduces the risk of stroke by 50%. The price of this drug is on average 220 UAH., Or 450 rubles.
Wazilip
This drug is prescribed for various forms of hypercholesterolemia, especially in combination with arteriosclerosis of the blood vessels and diabetes mellitus. Vasilip is used to prevent heart attack and stroke. The average cost of these pills is 150 UAH, or 320 rubles. These are inexpensive but effective pills that help to normalize the cholesterol in the blood.
Atoris
It is a complete analog of Atorvastatin. It prevents the formation of cholesterol from lipids. Also, Atoris helps to significantly increase the "good" cholesterol index. You can buy tablets for about 230 UAH., Or 500 rubles.
Roxer
This medicine lowers cholesterol. It is an effective drug with few side effects. Roxer is also prescribed for the prevention of cardiovascular pathologies in elderly people. The approximate price of this product is 90 UAH, or 250 rubles.
Rosart
The drug is used to normalize the level of cholesterol. It is contraindicated in cases of impaired liver function, active hepatitis, severe renal failure. Because of side effects, Rosart should be taken strictly following the instructions. Buy in a pharmacy this statin can be at an approximate price of 170 UAH., Or 400 rubles.
Deadlyl
One of the inexpensive and effective drugs. Contains rosuvastatin, has a long-lasting effect. To maximize the effectiveness should take Mortenil in complex therapy. The approximate price of the medicine is 150 UAH, or 300 rubles.
Rosacard
Helps to get rid of cholesterol. Also used to prevent heart disease and blood vessels, atherosclerosis. It has a number of contraindications and side effects, therefore it can be used only according to the doctor's prescription, strictly observing the dosage. You can buy Rosukard for about 180 UAH., Or 420 rubles.
Simvastatin
The drug is for a person with hypercholesterolemia. It is used as a component of complex therapy. Simvastatin is useful in the form of a preventive agent with concomitant diabetes, atherosclerosis. The average price of this product is 90 UAH, or 200 rubles.
Rosuvastatin
This is one of the most effective drugs for lowering cholesterol. Rosuvastatin has a long-lasting effect. You can buy tablets on average for 220 UAH., Or 500 rubles.
Important to remember! The safest statin will help to choose the attending physician, taking into account the individual characteristics of the patient's body and concomitant diseases!
Features of classification of statins
Classify statins can be in several ways:
- By generations: first, second, third and last generation.
- By origin: synthetic, semi-synthetic and natural.
- On the concentration of active substances: high-dose, medium-dose and low-dose.
The latter classification is most convenient, since statins are prescribed in different doses.
Natural statins from cholesterol
To lower the level of cholesterol in the blood prescribed a special diet. It is necessary, because some foods contain natural statins.
Reduction of cholesterol without medicines is possible when used:
- Products containing ascorbic acid. These include citrus, black currant, sea buckthorn, dog rose, sweet pepper.
- Products with nicotinic acid. These are all kinds of nuts, lean meat, red fish.
- Omega-3 fatty acids - red fish, any vegetable oil.
- Polikonazol. It is found in sugar cane, you can buy it in the pharmacy.
- Pectin. Its maximum concentration is noted in apples, carrots, cabbage, beans, cereals, bran.
- Resveratrol - grapes.
- Turmeric.
It also helps to reduce the cholesterol content of garlic.
Is it necessary to drink statins while following an anti-cholesterol diet? Proper nutrition is part of the therapy. Therefore, usually for the normalization of the condition, the patient changes his diet and takes medication of this group.
The benefits and harm of statins
Medicines of this group have a number of advantages. They include:
- Reducing the risk of death in the development of cardiovascular diseases.
- The probability of a heart attack decreases by 30%.
- With regular use of statins, cholesterol is reduced by 40-55%.
- Statins of the latest generation do not contain toxic substances. Side effects are observed in rare cases.
- Statins have many analogues. Everyone can choose the medicine that is suitable for him for the price.
Harm of statins is due to the fact that they can cause such reactions of the body:
- unreasonable mood changes, aggression, apathy, panic;
- general weakness of the body;
- defeat of non-inflammatory nerves;
- dysfunction of the digestive system;
- painful sensations in the joints and muscles;
- decrease in platelet concentration.
Statins can also lead to disruption of metabolic processes, so they must be used strictly following the instructions.
Contraindications
First of all, this group of drugs is contraindicated in women during pregnancy. It is also forbidden to use them in such cases:
- allergic manifestations, individual intolerance to drug components;
- serious kidney disease;
- disruption of the endocrine system;
- pathology of the musculoskeletal system;
- chronic liver disease.
If you use statins for a long time in a large dosage, they can cause such side effects:
- painful sensations in the gastrointestinal tract;
- constipation;
- nausea and vomiting;
- decreased platelet count;
- swelling of the upper and lower extremities;
- overweight, obesity;
- muscle cramps;
- backache;
- diseases of joints.
Also it is necessary to consider and compatibility of preparations at complex treatment. The use of statins incompatible with statins can lead to serious consequences.
Summing up, it should be noted that statins are quite safe and effective drugs, provided they are used correctly. When assessing the individual characteristics of the organism, accompanying illnesses of the patient, the attending physician will select the most effective remedy.