Tobrex

Tobrex is an antibacterial medicinal product that is intended for the treatment of various infectious eye diseases.

It is an eye drop, the basis of which is based on a broad-spectrum antibiotic called tobramycin. Tobramycin is active against a variety of pathogenic microflora, the active substance has a harmful effect on proteins, E. coli, staphylococcus and streptococci, klebsiella, gonococci, enterobacteria and other microorganisms.

Eye drops Tobrex are designed for topical application, so the active substance is not practically absorbed into the bloodstream. This explains the safety of the drug, the minimum amount of contraindications to its use and the absence of side effects.

Clinical and pharmacological group

Antibiotic of a group of aminoglycosides of a wide spectrum of action.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Tobrex cost in pharmacies? The average price is at the level of200 rubles.

Composition and form of release

Tobrex is available in the following dosage forms:

• eye drops , %: clear solution, colorless or light yellow (5 ml in Droptainer dropper bottles, one bottle in a cardboard bundle);
• ointment eye 0.3%: homogeneous, white or almost white (3.5 grams in aluminum tubes, in a cardboard bundle one tube).

Composition of 1 ml eye drops:

• active substance: tobramycin - 3 mg;
• auxiliary components: benzalkonium chloride solution, sodium sulfate anhydrous, tyloxapol, boric acid, sodium hydroxide and / or sulfuric acid (for pH adjustment), sodium chloride, purified water.

Composition 1 g ointment ophthalmic:

• active substance: tobramycin - 3 mg;
• auxiliary components: petrolatum white, mineral oil (liquid paraffin), chlorobutanol anhydrous.

pharmachologic effect

The basis of the drug tobrebs are substances that disrupt the membrane cells of pathogenic microorganisms and suppress the synthesis of protein in them. This effect extends to the causative agents of diphtheria, staphylococcus, streptococcus and Escherichia coli. The main active component of drops is the antibiotic tobramycin.

The disadvantage of this antibacterial component is that it operates only with systematic instillations. If the instillation is discontinued, the surviving pathogenic microorganisms will begin to multiply again. This can be avoided by increasing the amount and dosage of instillations, but in this case there is a risk of side effects.

The advantages of the drug include its speed: the first symptoms of the diseases are eliminated during the first hours after instillation, but if the disease has turned into a serious form - positive results should be expected at least three days after the start of treatment.

Indications for use

According to the instructions for use, eye drops Tobrex prescribe when the eyes are affected by bacteria that cause a number of diseases:

• blepharitis (chronic inflammation of the eyelids caused by golden staphylococcus);
• conjunctivitis (inflammatory process on the mucous membranes of the eyes);
• keratitis (inflammation, turbidity of sclera and ulceration on the cornea of ​​the eyeball);
• blepharoconjunctivitis and keratoconjunctivitis;
• Idocyclitis (inflammation of the iris of the eye and its vascular membrane).

Contraindications

Individual hypersensitivity to the drug and its components.

Caution should be given to tobramycin in patients in childhood, during pregnancy and breastfeeding.

Intended use for pregnancy and lactation

There is no unequivocal opinion about the use of the drug for the treatment of women during pregnancy and lactation, since There is insufficient experience on the use of this drug by the above-mentioned groups of patients. Therefore, the use of Tobrex for the treatment of pregnant women is justified only if the expected therapeutic effect exceeds the risk of side effects.

Dosage and route of administration

As indicated in the instructions for use, the Tobrex drops are for topical application by instillation into the conjunctival sac.

Recommended dosing:

• non-severe infections: 1-2 drops every 4 hours;
• acute period of severe infections: 2 drops every hour, then as the inflammatory process decreases, the instillation frequency should be reduced.

When using drops, it is not recommended to wear soft lenses. If lenses still use, then they need to be removed before instillation and put on not earlier than 15 minutes after instillation.

It is not recommended after driving in less than 30 minutes, drive the vehicle or work with potentially dangerous equipment.

Tobex for children

Children older than one year are prescribed Tobrex 1 drop 5 times a day. The course of treatment - no more than 7 days.

Tobrex for newborns

Despite the fact that the instruction to the drug has an indication of an inadequate study of the use of Tobrex in children up to 1 year, the practical experience of pediatricians testifies to the high efficiency of Tobrex in newborns. It is also positive that the effect comes quickly, without requiring long-term treatment.

Tobrex is prescribed to newborn children 1 drop five times a day, not more than 7 days.

With proper compliance with the dosage of complications does not occur. If the recommendations of the doctor are violated, an overdose of the drug in the baby may cause hearing damage, impaired kidney function, paralysis of the respiratory muscles. At occurrence of any deviations it is necessary to stop treatment Tobreksom and to address to the pediatrist or the children's oculist.

Do not use Tobres alone without prescribing a doctor to your child!

Side effects

In general, eye drops Tobreks are transferred well enough. Sometimes, against the background of their use, it is possible to develop local allergic reactions in the form of redness of the conjunctiva, swelling of the eyelids. In this case, the use of the drug should be discontinued and consult a medical professional.

Overdose

In case of excessive instillation with Tobrex solution, a sensation of burning, swelling of the eyelids, reddening of the conjunctiva may appear. In this case, symptomatic therapy is performed.

special instructions

Unreasonable increase in the frequency of administration and duration of use of the drug may lead to the appearance insensitive to the components of the preparation of microorganisms, including fungal infection of the eye. If symptoms of superinfection occur, it is recommended that you consult a doctor.

Interaction with other drugs

It is necessary to exclude the joint use of Tobrex with the following drugs:

• with capreomycin, carboplatinum, teicoplanin, cefepime, cefotaxime, t. oto- and nephrotoxic effect is observed;
• with vancomycin, tk. oto-, nephro- and neurotochemical effect is observed;
• with ethacrylic acid or furosemide, because ototoxic effect is observed;
• with cifamandol, cefapazone, cefuroxime, amphotericin B, because nephrotoxic effect is observed.

Also, do not simultaneously use Tobrex with drugs that have in the composition tetracycline (due to the content in the first tyloxapol).

Reviews

We offer you to familiarize yourself with the opinions of people who used Tobrex drops:

1. Svetlana. Tobrex in conjunctivitis is very helpful. The eyes do not twitch, it passes quickly. The child treated as follows: 3-4 times albucite in the eye (7 days), 1 time in the evening tobrebs and at night tetracycline ointment 7 days + 2 days for prophylaxis). Everything passes in a week.
2. Masha. To my child droplets Tobreks for eyes have appointed or nominated still in a maternity home. The baby had an inflammatory process in the tear duct. Bury the medicine in the eyes twice a day. In the early days of the son flowed tears all the time, but after 2 days everything stopped. Only about 5 days used this medicine. I was worried, but the pediatrician explained that there would be no harm from him. Active substance Tobreksa does not penetrate into the blood, it acts only at the local level, so nothing can harm the baby.
3. Nastya. I drip these eyes with blepharitis. I love. There is an effect. And the eye reacts well to them, I do not observe side reactions. Since blepharitis is almost not treated, I periodically use these droplets. At the first reddening I start to drip my eyes And I am very pleased with them!

Analogues

Analogues of Tobrex are: drops - Tobrup, Tobrex 2X, Dilaterol, Tobrosopt; ointments - Gentamicin, Levomycetin, Kolbiotin, Erythromycin.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Keep away from children.

Store at a temperature of 8-30 ° C.

Shelf life - 3 years.

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